Reumatología Clínica (English Edition) Reumatología Clínica (English Edition)
Case Report
Visceral Leishmaniasis in a Rheumatoid Arthritis Patient Receiving Methotrexate
Kala-azar en un paciente con artritis reumatoide tratada con metotrexato
Delia Reinaa,, , Dacia Cerdàa, Elena Güellb, Joaquín Martínez Montautib, Antonio Pinedac, Hèctor Corominasa
a Servicio de Reumatología, Hospital Moisès Broggi, Consorci Sanitari Integral, Sant Joan Despí, Barcelona, Spain
b Servicio de Medicina Interna, Hospital de Barcelona, Barcelona, Spain
c Servicio de Hematología, Hospital de Barcelona, Barcelona, Spain
Received 12 May 2016, Accepted 14 July 2016
Abstract

Patients with rheumatoid arthritis (RA) treated with disease-modifying antirheumatic drugs are susceptible to severe infections such as leishmaniasis. As L. infantum is endemic in the Mediterranean region, it is necessary to rule this infectious process out in any RA patient presenting with fever and pancytopenia. An early diagnosis based on a high suspicion can prevent a fatal outcome.

Resumen

Los pacientes con artritis reumatoide (AR) tratados con fármacos modificadores del curso de la enfermedad están expuestos a desarrollar infecciones potencialmente graves como la leishmaniasis. L. infantum es endémica en el Mediterráneo, hecho que obliga ante un paciente con AR que presenta fiebre y pancitopenia, a descartar este proceso. Un diagnóstico de sospecha precoz, puede evitar un curso y pronóstico fatal.

Keywords
Kala-azar, Rheumatoid arthritis, Methotrexate
Palabras clave
Kala-azar, Artritis reumatoide, Metotrexato

Article

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