Reumatología Clínica (English Edition) Reumatología Clínica (English Edition)
Case report
Hyponatremia as presentation in a patient with neurosarcoidosis
Hiponatremia como presentación en un paciente con neurosarcoidosis
Ekin Akyildiza, Murat Yalcina, Fidan Severb, Hüseyin Semiza, Senol Kobakc,,
a Sifa University, Faculty of Medicine, Department of Rheumatology, Turkey
b Sifa University, Faculty of Medicine, Department of Chest Diseases, Turkey
c Istinye University, Faculty of Medicine, LIV Hospital, Department of Rheumatology, Turkey
Received 19 May 2016, Accepted 12 August 2016

Sarcoidosis is an inflammatory disease with unknown cause characterized by non-caseating granuloma formations. It may present with bilateral hilar lymphadenopathy, skin lesions, eye and musculoskeletal system involvement. Hypercalcemia and hypercalciuria are important electrolyte imbalances resulting from sarcoidosis and sometimes they may cause nephrolitiasis and kidney failure. Hyponatremia, although being quite rare, has been found in some patients with sarcoidosis. Herein, we have reported a patient with neurosarcoidosis who presented with hyponatremia and responded well to corticosteroid treatment.


La sarcoidosis es una enfermedad inflamatoria, de causa desconocida, que se caracteriza por la formación de granulomas no caseificantes. Se puede presentar con linfadenopatía hiliar bilateral, lesiones en la piel, en los ojos, y la implicación del sistema musculoesquelético. La hipercalcemia y la hipercalciuria son importantes desequilibrios electrolíticos resultantes de la sarcoidosis, y algunas veces pueden causar nefrolitiasis e insuficiencia renal. La hiponatremia, a pesar de ser bastante rara, se ha encontrado en algunos pacientes con sarcoidosis. Aquí, hemos informado de un paciente con neurosarcoidosis que se presentó con hiponatremia y respondió bien al tratamiento con glucocorticoides.

Hyponatremia, Neurosarcoidosis, Presentation
Palabras clave
Hiponatremia, Neurosarcoidosis, Presentación


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