Reumatología Clínica (English Edition) Reumatología Clínica (English Edition)
Case report
Necrotizing fasciitis in a patient receiving tocilizumab for rheumatoid arthritis • Case report
Fascitis necrosante en un paciente bajo tocilizumab para la artritis reumatoide. Presentación de un caso
Diana Rosa-Gonçalves, , Miguel Bernardes, Lúcia Costa
Rheumatology Department, Centro Hospitalar São João, Portugal
Received 03 August 2016, Accepted 28 October 2016

We present a case of necrotizing fasciitis in a 66-year-old Caucasian woman with rheumatoid arthritis receiving tocilizumab, and provide a review of published cases. The patient exhibited no systemic symptoms and discreet cutaneous inflammatory signals at presentation. She was successfully treated with broad-spectrum empiric antibiotic therapy and surgical debridement.


Presentamos un caso de fascitis necrosante en una mujer caucásica de 66 años de edad con artritis reumatoide en tratamiento con tocilizumab y se ha realizado una revisión de casos publicados. La paciente ha presentado falta de síntomas sistèc)micos y señales inflamatorias cutáneas discretas. Ha sido tratada con èc)xito con terapia antibiótica empírica de amplio espectro y desbridamiento quirúrgico.

Rheumatoid arthritis, Infection, Necrotizing fasciitis, Skin, Tocilizumab, Tumor necrosis factor antagonists
Palabras clave
Artritis reumatoide, Infección, Fascitis necrosante, Piel, Tocilizumab, Antagonistas del factor de necrosis tumoral alfa


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