array:23 [
  "pii" => "S2173574308701655"
  "issn" => "21735743"
  "doi" => "10.1016/S2173-5743(08)70165-5"
  "estado" => "S300"
  "fechaPublicacion" => "2008-05-01"
  "aid" => "70165"
  "copyright" => "Sociedad Española de Reumatología and Colegio Mexicano de Reumatología"
  "copyrightAnyo" => "2008"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Reumatol Clin. 2008;4:96-9"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 1795
    "formatos" => array:3 [
      "EPUB" => 39
      "HTML" => 1247
      "PDF" => 509
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S2173574308701667"
    "issn" => "21735743"
    "doi" => "10.1016/S2173-5743(08)70166-7"
    "estado" => "S300"
    "fechaPublicacion" => "2008-05-01"
    "aid" => "70166"
    "copyright" => "Sociedad Española de Reumatología and Colegio Mexicano de Reumatología"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Reumatol Clin. 2008;4:100-6"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 1852
      "formatos" => array:3 [
        "EPUB" => 37
        "HTML" => 1244
        "PDF" => 571
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Validity and Usefulness of Echography in the Carpal Tunnel Syndrome"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "100"
          "paginaFinal" => "106"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Validez y utilidad de la ecografía en el síndrome del túnel carpiano"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Diana Peiteado López, Cristina Bohórquez Heras, Eugenio de Miguel Mendieta, Susana Santiago Pérez, Arturo Ugalde Canitro, Emilio Martín Mola"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Diana"
              "apellidos" => "Peiteado López"
            ]
            1 => array:2 [
              "nombre" => "Cristina"
              "apellidos" => "Bohórquez Heras"
            ]
            2 => array:2 [
              "nombre" => "Eugenio"
              "apellidos" => "de Miguel Mendieta"
            ]
            3 => array:2 [
              "nombre" => "Susana"
              "apellidos" => "Santiago Pérez"
            ]
            4 => array:2 [
              "nombre" => "Arturo"
              "apellidos" => "Ugalde Canitro"
            ]
            5 => array:2 [
              "nombre" => "Emilio"
              "apellidos" => "Martín Mola"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574308701667?idApp=UINPBA00004M"
    "url" => "/21735743/0000000400000003/v1_201305061545/S2173574308701667/v1_201305061545/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S2173574308701643"
    "issn" => "21735743"
    "doi" => "10.1016/S2173-5743(08)70164-3"
    "estado" => "S300"
    "fechaPublicacion" => "2008-05-01"
    "aid" => "70164"
    "copyright" => "Sociedad Española de Reumatología and Colegio Mexicano de Reumatología"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Reumatol Clin. 2008;4:90-5"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2123
      "formatos" => array:3 [
        "EPUB" => 41
        "HTML" => 1456
        "PDF" => 626
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Adverse Reactions Related to the Administration of TNF Inhibitors. Analysis of a Registry of Biologic Therapy"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "90"
          "paginaFinal" => "95"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Reacciones adversas relacionadas con la administración de inhibidores del TNF. Análisis de un registro de terapias biológicas"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Beatriz Pérez-Zafrilla, Miguel Ángel Descalzo, Loreto Carmona"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Beatriz"
              "apellidos" => "Pérez-Zafrilla"
            ]
            1 => array:2 [
              "nombre" => "Miguel"
              "apellidos" => "Ángel Descalzo"
            ]
            2 => array:2 [
              "nombre" => "Loreto"
              "apellidos" => "Carmona"
            ]
            3 => array:1 [
              "colaborador" => "the BIOBADASER study group"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574308701643?idApp=UINPBA00004M"
    "url" => "/21735743/0000000400000003/v1_201305061545/S2173574308701643/v1_201305061545/en/main.assets"
  ]
  "en" => array:14 [
    "idiomaDefecto" => true
    "titulo" => "Effect of the Coexistence of Fibromyalgia in the DAS28 Index in Women With Rheumatoid Arthritis"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "96"
        "paginaFinal" => "99"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Daniel Roig Vilaseca, Carmen Hoces Otero"
        "autores" => array:2 [
          0 => array:4 [
            "nombre" => "Daniel"
            "apellidos" => "Roig Vilaseca"
            "email" => array:1 [
              0 => "26188drv@comb.es"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "Carmen"
            "apellidos" => "Hoces Otero"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Unitat de Reumatolog&#237;a&#44; Centre d&#8217;Atenci&#243; Especialitzada Cornell&#224;&#44; Servei d&#8217;Atenci&#243; Prim&#224;ria Baix Llobregat Centre&#44; Cornell&#224; de Llobregat&#44; Barcelona&#44; Spain"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Correspondence&#58; Unitat de Reumatologia&#46; Centre d&#8217;Atenci&#243; Especialitzada Cornell&#224;&#46; Servei d&#8217;Atenci&#243; Prim&#224;ria Baix Llobregat Centre&#46; Bellaterra&#44; 41&#46; 08940 Cornell&#224; de Llobregat&#46; Barcelona&#46; Espa&#241;a&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Efecto de la coexistencia de fibromialgia en el &#237;ndice DAS28 en mujeres con artritis reumatoide"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2007-12-12"
    "fechaAceptado" => "2008-03-04"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Key words"
          "identificador" => "xpalclavsec111817"
          "palabras" => array:4 [
            0 => "Rheumatoid arthritis"
            1 => "Fibromyalgia"
            2 => "Disease Activity Score"
            3 => "DAS28"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec111816"
          "palabras" => array:4 [
            0 => "Artritis reumatoide"
            1 => "Fibromialgia"
            2 => "<span class="elsevierStyleItalic">Disease Activity Score</span>"
            3 => "DAS28"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To compare the effect of coexisting fibromyalgia in DAS28 in RA female patients&#46;</p> <span class="elsevierStyleSectionTitle">Patients and method</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Fifty-three RA women seen consecutively in an outpatient rheumatology clinic were included and classified according to the presence &#40;9 women&#41; or absence &#40;44 women&#41; of fibromyalgia&#46; ESR&#44; number of tender and swollen joints&#44; and global assessment by the patient through a visual analogue scale were recorded&#44; as well as other functional and emotional variables&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">There were no differences in age&#44; time since onset of the arthritis&#44; number of swollen joints&#44; ESR&#44; and CRP&#46; Number of tender joints&#44; global assessment by the patient&#44; and functional and emotional aspects were worse in patients with fibromyalgia&#46; DAS28 was higher when fibromyalgia was associated to RA &#40;5&#46;55 &#91;0&#46;78&#93; vs 3&#46;39 &#91;1&#46;15&#93;&#59; <span class="elsevierStyleItalic">P</span>&#61;&#46;000&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Coexistence of fibromyalgia increases DAS28 in women with RA&#46;</p>"
      ]
      "es" => array:1 [
        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Evaluar el efecto de la coexistencia de fibromialgia y artritis reumatoide en el valor del &#237;ndice DAS28 en mujeres&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todo</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Se incluy&#243; a 53 mujeres con artritis reumatoide &#40;9 con fibromialgia y 44 sin fibromialgia&#41; visitadas de forma consecutiva en una consulta extrahospitalaria de reumatolog&#237;a&#46; Se recogieron la velocidad de sedimentaci&#243;n globular &#40;VSG&#41;&#44; la PCR&#44; el n&#250;mero de articulaciones dolorosas y tumefactas&#44; la valoraci&#243;n general de las pacientes mediante escala visual anal&#243;gica y otros par&#225;metros referentes a la enfermedad articular y el estado funcional y emocional de las pacientes&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">No se encontraron diferencias significativas en la edad de las pacientes&#44; la duraci&#243;n de la artritis&#44; el n&#250;mero de articulaciones tumefactas&#44; la VSG y la PCR&#59; por el contrario&#44; hubo diferencias en el n&#250;mero de articulaciones dolorosas&#44; la evaluaci&#243;n global de la enfermedad por las pacientes y en aspectos funcionales y emocionales&#46; El DAS28 fue mayor en las mujeres que ten&#237;an fibromialgia asociada &#40;5&#44;55 &#177; 0&#44;78 frente a 3&#44;39 &#177; 1&#44;15&#59; p &#61; 0&#44;000&#41;&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">La coexistencia de fibromialgia en mujeres con artritis reumatoide se asocia a un mayor valor del DAS28&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:10 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalence of primary and secondary fibromyalgia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "F&#46; Wolfe"
                            1 => "M&#46;A&#46; Catie"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Rheumatol"
                        "fecha" => "1983"
                        "volumen" => "10"
                        "paginaInicial" => "965"
                        "paginaFinal" => "968"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/6582268"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fibromyalgia in patients with rheumatoid arthritis is associated with higher scores of disability"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A&#46; Naranjo"
                            1 => "S&#46; Ojeda"
                            2 => "F&#46; Francisco"
                            3 => "C&#46; Erausquin"
                            4 => "I&#46; R&#250;a-Figueroa"
                            5 => "C&#46; Rodr&#237;guez-Lozano"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Rheum Dis"
                        "fecha" => "2002"
                        "volumen" => "61"
                        "paginaInicial" => "660"
                        "paginaFinal" => "661"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12079919"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Severe rheumatoid arthritis &#40;RA&#41;&#44; worse outcomes&#44; comorbid illness&#44; and sociodemographic disadvantage characterize RA patients with fibromyalgia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Wolfe"
                            1 => "K&#46; Michaud"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Rheumatol"
                        "fecha" => "2004"
                        "volumen" => "31"
                        "paginaInicial" => "695"
                        "paginaFinal" => "700"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15088293"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The American Rheumathism Association 1987 revised criteria for the classification of rheumatoid arthritis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46;C&#46; Arnett"
                            1 => "S&#46;M&#46; Edworthy"
                            2 => "D&#46;A&#46; Bloch"
                            3 => "D&#46;J&#46; McShane"
                            4 => "F&#46;J&#46; Fries"
                            5 => "N&#46;S&#46; Cooper"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arthritis Rheum"
                        "fecha" => "1988"
                        "volumen" => "31"
                        "paginaInicial" => "315"
                        "paginaFinal" => "324"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/3358796"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The American College of Rheumatology 1990 criteria for the classification of fibromyalgia&#46; Report of the multicenter criteria committee"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46; Wolfe"
                            1 => "H&#46;A&#46; Smythe"
                            2 => "M&#46;B&#46; Yunus"
                            3 => "R&#46;M&#46; Bennett"
                            4 => "C&#46; Bombardier"
                            5 => "D&#46;L&#46; Goldenberg"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arthritis Rheum"
                        "fecha" => "1990"
                        "volumen" => "33"
                        "paginaInicial" => "160"
                        "paginaFinal" => "172"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/2306288"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The burden of musculoskeletal disease in the general population of Spain&#58; Results from a national survey"
                      "autores" => array:1 [
                        0 => array:3 [
                          "colaboracion" => "EPISER study group"
                          "etal" => false
                          "autores" => array:4 [
                            0 => "L&#46; Carmona"
                            1 => "J&#46; Ballina"
                            2 => "R&#46; Gabriel"
                            3 => "A&#46; Laffon"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Rheum Dis"
                        "fecha" => "2001"
                        "volumen" => "60"
                        "paginaInicial" => "1040"
                        "paginaFinal" => "1045"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11602475"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "&#191;C&#243;mo se eval&#250;a una respuesta inadecuada en un paciente con artritis reumatoide en la pr&#225;ctica cl&#237;nica&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46; Balsa"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S1699-258X(07)73597-0"
                      "Revista" => array:6 [
                        "tituloSerie" => "Reumatol Clin"
                        "fecha" => "2007"
                        "volumen" => "3"
                        "paginaInicial" => "38"
                        "paginaFinal" => "44"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21794394"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Development and validation of the European League Against Rheumatism response criteria for rheumatoid artritis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A&#46;M&#46; van Gestel"
                            1 => "M&#46;L&#46; Prevoo"
                            2 => "M&#46;A&#46; van&#8217;t Hof"
                            3 => "M&#46;H&#46; van Rijswijk"
                            4 => "P&#46;L&#46;B&#46; van-de"
                            5 => "P&#46;L&#46; van Riel"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Arthritis Rheum"
                        "fecha" => "1996"
                        "volumen" => "39"
                        "paginaInicial" => "34"
                        "paginaFinal" => "40"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/8546736"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "III Actualizaci&#243;n del Consenso de la Sociedad Espa&#241;ola de Reumatolog&#237;a sobre terapia biol&#243;gica en la artritis reumatoide"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "V&#46; Rodr&#237;guez-Valverde"
                            1 => "R&#46; C&#225;liz C&#225;liz"
                            2 => "J&#46;M&#46; &#193;lvaro-Gracia &#193;lvaro"
                            3 => "J&#46;L&#46; Marenco de la Fuente"
                            4 => "J&#46; Mulero Mendoza"
                            5 => "J&#46; Tornero Molina"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S1699-258X(06)73097-2"
                      "Revista" => array:7 [
                        "tituloSerie" => "Reumatol Clin"
                        "fecha" => "2006"
                        "volumen" => "2"
                        "numero" => "Suppl 2"
                        "paginaInicial" => "S52"
                        "paginaFinal" => "S59"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21794377"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The DAS28 in rheumatoid arthritis and fibromyalgia patients"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "B&#46;F&#46; Leeb"
                            1 => "I&#46; Andel"
                            2 => "J&#46; Sautner"
                            3 => "T&#46; Nothnagl"
                            4 => "B&#46; Rintelen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1093/rheumatology/keh322"
                      "Revista" => array:7 [
                        "tituloSerie" => "Rheumatology"
                        "fecha" => "2004"
                        "volumen" => "43"
                        "paginaInicial" => "1504"
                        "paginaFinal" => "1507"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15252215"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0140673611608271"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735743/0000000400000003/v1_201305061545/S2173574308701655/v1_201305061545/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "17338"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Original Article"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735743/0000000400000003/v1_201305061545/S2173574308701655/v1_201305061545/en/main.pdf?idApp=UINPBA00004M&text.app=https://reumatologiaclinica.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574308701655?idApp=UINPBA00004M"
]
Share
Journal Information
Vol. 4. Issue 3.
Pages 96-99 (May - June 2008)
Share
Share
Download PDF
More article options
Vol. 4. Issue 3.
Pages 96-99 (May - June 2008)
Full text access
Effect of the Coexistence of Fibromyalgia in the DAS28 Index in Women With Rheumatoid Arthritis
Efecto de la coexistencia de fibromialgia en el índice DAS28 en mujeres con artritis reumatoide
Visits
4804
Daniel Roig Vilaseca
Corresponding author
26188drv@comb.es

Correspondence: Unitat de Reumatologia. Centre d’Atenció Especialitzada Cornellà. Servei d’Atenció Primària Baix Llobregat Centre. Bellaterra, 41. 08940 Cornellà de Llobregat. Barcelona. España.
, Carmen Hoces Otero
Unitat de Reumatología, Centre d’Atenció Especialitzada Cornellà, Servei d’Atenció Primària Baix Llobregat Centre, Cornellà de Llobregat, Barcelona, Spain
This item has received
Article information
Objective

To compare the effect of coexisting fibromyalgia in DAS28 in RA female patients.

Patients and method

Fifty-three RA women seen consecutively in an outpatient rheumatology clinic were included and classified according to the presence (9 women) or absence (44 women) of fibromyalgia. ESR, number of tender and swollen joints, and global assessment by the patient through a visual analogue scale were recorded, as well as other functional and emotional variables.

Results

There were no differences in age, time since onset of the arthritis, number of swollen joints, ESR, and CRP. Number of tender joints, global assessment by the patient, and functional and emotional aspects were worse in patients with fibromyalgia. DAS28 was higher when fibromyalgia was associated to RA (5.55 [0.78] vs 3.39 [1.15]; P=.000).

Conclusions

Coexistence of fibromyalgia increases DAS28 in women with RA.

Key words:
Rheumatoid arthritis
Fibromyalgia
Disease Activity Score
DAS28
Objetivo

Evaluar el efecto de la coexistencia de fibromialgia y artritis reumatoide en el valor del índice DAS28 en mujeres.

Pacientes y método

Se incluyó a 53 mujeres con artritis reumatoide (9 con fibromialgia y 44 sin fibromialgia) visitadas de forma consecutiva en una consulta extrahospitalaria de reumatología. Se recogieron la velocidad de sedimentación globular (VSG), la PCR, el número de articulaciones dolorosas y tumefactas, la valoración general de las pacientes mediante escala visual analógica y otros parámetros referentes a la enfermedad articular y el estado funcional y emocional de las pacientes.

Resultados

No se encontraron diferencias significativas en la edad de las pacientes, la duración de la artritis, el número de articulaciones tumefactas, la VSG y la PCR; por el contrario, hubo diferencias en el número de articulaciones dolorosas, la evaluación global de la enfermedad por las pacientes y en aspectos funcionales y emocionales. El DAS28 fue mayor en las mujeres que tenían fibromialgia asociada (5,55 ± 0,78 frente a 3,39 ± 1,15; p = 0,000).

Conclusiones

La coexistencia de fibromialgia en mujeres con artritis reumatoide se asocia a un mayor valor del DAS28.

Palabras clave:
Artritis reumatoide
Fibromialgia
Disease Activity Score
DAS28
Full text is only aviable in PDF
References
[1.]
F. Wolfe, M.A. Catie.
Prevalence of primary and secondary fibromyalgia.
J Rheumatol, 10 (1983), pp. 965-968
[2.]
A. Naranjo, S. Ojeda, F. Francisco, C. Erausquin, I. Rúa-Figueroa, C. Rodríguez-Lozano.
Fibromyalgia in patients with rheumatoid arthritis is associated with higher scores of disability.
Ann Rheum Dis, 61 (2002), pp. 660-661
[3.]
J. Wolfe, K. Michaud.
Severe rheumatoid arthritis (RA), worse outcomes, comorbid illness, and sociodemographic disadvantage characterize RA patients with fibromyalgia.
J Rheumatol, 31 (2004), pp. 695-700
[4.]
F.C. Arnett, S.M. Edworthy, D.A. Bloch, D.J. McShane, F.J. Fries, N.S. Cooper, et al.
The American Rheumathism Association 1987 revised criteria for the classification of rheumatoid arthritis.
Arthritis Rheum, 31 (1988), pp. 315-324
[5.]
F. Wolfe, H.A. Smythe, M.B. Yunus, R.M. Bennett, C. Bombardier, D.L. Goldenberg, et al.
The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the multicenter criteria committee.
Arthritis Rheum, 33 (1990), pp. 160-172
[6.]
L. Carmona, J. Ballina, R. Gabriel, A. Laffon, EPISER study group.
The burden of musculoskeletal disease in the general population of Spain: Results from a national survey.
Ann Rheum Dis, 60 (2001), pp. 1040-1045
[7.]
A. Balsa.
¿Cómo se evalúa una respuesta inadecuada en un paciente con artritis reumatoide en la práctica clínica?.
Reumatol Clin, 3 (2007), pp. 38-44
[8.]
A.M. van Gestel, M.L. Prevoo, M.A. van’t Hof, M.H. van Rijswijk, P.L.B. van-de, P.L. van Riel.
Development and validation of the European League Against Rheumatism response criteria for rheumatoid artritis.
Arthritis Rheum, 39 (1996), pp. 34-40
[9.]
V. Rodríguez-Valverde, R. Cáliz Cáliz, J.M. Álvaro-Gracia Álvaro, J.L. Marenco de la Fuente, J. Mulero Mendoza, J. Tornero Molina, et al.
III Actualización del Consenso de la Sociedad Española de Reumatología sobre terapia biológica en la artritis reumatoide.
Reumatol Clin, 2 (2006), pp. S52-S59
[10.]
B.F. Leeb, I. Andel, J. Sautner, T. Nothnagl, B. Rintelen.
The DAS28 in rheumatoid arthritis and fibromyalgia patients.
Rheumatology, 43 (2004), pp. 1504-1507
Copyright © 2008. Sociedad Española de Reumatología and Colegio Mexicano de Reumatología
Download PDF
Idiomas
Reumatología Clínica (English Edition)
Article options
Tools
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?