Responsiveness of Outcome Measures
Sensibilidad al cambio de las medidas de desenlace
María Jesús García de Yébenes Prousa,
, Francisco Rodríguez Salvanésb, Loreto Carmona Ortellsa
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mjesus.garciadeyebenes@ser.es
Correspondence: Unidad de Investigación. Fundación Española de Reumatología. Marqués del Duero, 5, 1.° A. 28001 Madrid. España.
Correspondence: Unidad de Investigación. Fundación Española de Reumatología. Marqués del Duero, 5, 1.° A. 28001 Madrid. España.
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Fundación Española de Reumatología. Marqués del Duero, 5, 1.° A. 28001 Madrid. España." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Sensibilidad al cambio de las medidas de desenlace" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-06-27" "fechaAceptado" => "2008-07-24" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Key words" "identificador" => "xpalclavsec111945" "palabras" => array:3 [ 0 => "Responsiveness" 1 => "Outcome measures" 2 => "Responsiveness statistics" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec111944" "palabras" => array:3 [ 0 => "Sensibilidad al cambio" 1 => "Medidas de desenlace" 2 => "Estadísticos de sensibilidad al cambio" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">In medical research, particularly in the field of rheumatology, there is great interest about the concept of responsiveness of outcome measures as a sign of changes in the patient's health status. However, the terminology surrounding this concept and the methods of analysis are confusing and lacking in consensus.</p><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">We present a review about the concept and analysis of responsiveness taking into account both, the characteristics of the responsiveness and the type of design and predictable change in the sample being studied.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">En la investigación médica, y en especial en el ámbito de la reumatología, hay gran interés sobre el concepto de sensibilidad al cambio de un instrumento de medida como posible reflejo de modificaciones en la situación clínica del paciente. Sin embargo, la terminología de este concepto y su metodología de análisis están rodeadas de confusión y falta de consenso.</p><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Se presenta un trabajo de revisión sobre el concepto y el análisis de la sensibilidad al cambio teniendo en cuenta tanto las características de la sensibilidad como el tipo de diseño y cambio previsible en la muestra en estudio.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Measuring health status: what are the necessary measurement properties?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "G.H. Guyatt" 1 => "B. Kirshner" 2 => "R. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 6 | 16 | 22 |
| 2024 October | 33 | 77 | 110 |
| 2024 September | 28 | 30 | 58 |
| 2024 August | 38 | 42 | 80 |
| 2024 July | 34 | 33 | 67 |
| 2024 June | 29 | 77 | 106 |
| 2024 May | 38 | 56 | 94 |
| 2024 April | 32 | 66 | 98 |
| 2024 March | 32 | 62 | 94 |
| 2024 February | 17 | 55 | 72 |
| 2024 January | 21 | 63 | 84 |
| 2023 December | 15 | 85 | 100 |
| 2023 November | 16 | 28 | 44 |
| 2023 October | 25 | 58 | 83 |
| 2023 September | 56 | 44 | 100 |
| 2023 August | 26 | 29 | 55 |
| 2023 July | 15 | 34 | 49 |
| 2023 June | 19 | 32 | 51 |
| 2023 May | 15 | 21 | 36 |
| 2023 April | 10 | 23 | 33 |
| 2023 March | 30 | 35 | 65 |
| 2023 February | 17 | 33 | 50 |
| 2023 January | 21 | 27 | 48 |
| 2022 December | 28 | 34 | 62 |
| 2022 November | 30 | 38 | 68 |
| 2022 October | 19 | 42 | 61 |
| 2022 September | 44 | 41 | 85 |
| 2022 August | 68 | 51 | 119 |
| 2022 July | 47 | 60 | 107 |
| 2022 June | 51 | 53 | 104 |
| 2022 May | 38 | 44 | 82 |
| 2022 April | 29 | 63 | 92 |
| 2022 March | 38 | 57 | 95 |
| 2022 February | 19 | 32 | 51 |
| 2022 January | 24 | 37 | 61 |
| 2021 December | 21 | 43 | 64 |
| 2021 November | 23 | 54 | 77 |
| 2021 October | 40 | 52 | 92 |
| 2021 September | 21 | 36 | 57 |
| 2021 August | 26 | 42 | 68 |
| 2021 July | 17 | 35 | 52 |
| 2021 June | 17 | 46 | 63 |
| 2021 May | 21 | 25 | 46 |
| 2021 April | 90 | 65 | 155 |
| 2021 March | 40 | 47 | 87 |
| 2021 February | 37 | 22 | 59 |
| 2021 January | 31 | 22 | 53 |
| 2020 December | 36 | 22 | 58 |
| 2020 November | 21 | 19 | 40 |
| 2020 October | 9 | 5 | 14 |
| 2020 September | 32 | 32 | 64 |
| 2020 August | 15 | 18 | 33 |
| 2020 July | 17 | 23 | 40 |
| 2020 June | 19 | 23 | 42 |
| 2020 May | 30 | 12 | 42 |
| 2020 April | 27 | 11 | 38 |
| 2020 March | 29 | 11 | 40 |
| 2020 February | 5 | 0 | 5 |
| 2020 January | 4 | 0 | 4 |
| 2019 December | 3 | 0 | 3 |
| 2019 September | 4 | 0 | 4 |
| 2019 July | 2 | 0 | 2 |
| 2019 June | 2 | 0 | 2 |
| 2019 March | 4 | 0 | 4 |
| 2019 January | 1 | 0 | 1 |
| 2018 December | 1 | 0 | 1 |
| 2018 May | 2 | 1 | 3 |
| 2018 April | 20 | 8 | 28 |
| 2018 March | 40 | 11 | 51 |
| 2018 February | 10 | 3 | 13 |
| 2018 January | 11 | 5 | 16 |
| 2017 December | 14 | 6 | 20 |
| 2017 November | 14 | 7 | 21 |
| 2017 October | 18 | 10 | 28 |
| 2017 September | 10 | 8 | 18 |
| 2017 August | 9 | 7 | 16 |
| 2017 July | 13 | 10 | 23 |
| 2017 June | 26 | 20 | 46 |
| 2017 May | 27 | 12 | 39 |
| 2017 April | 19 | 7 | 26 |
| 2017 March | 20 | 7 | 27 |
| 2017 February | 8 | 6 | 14 |
| 2017 January | 16 | 7 | 23 |
| 2016 December | 37 | 15 | 52 |
| 2016 November | 20 | 3 | 23 |
| 2016 October | 36 | 8 | 44 |
| 2016 September | 29 | 8 | 37 |
| 2016 August | 29 | 10 | 39 |
| 2016 July | 12 | 5 | 17 |
| 2016 April | 1 | 0 | 1 |
| 2016 March | 1 | 0 | 1 |
| 2015 December | 3 | 0 | 3 |
| 2015 November | 1 | 0 | 1 |
| 2015 October | 1 | 0 | 1 |
| 2015 July | 8 | 5 | 13 |
| 2015 June | 13 | 8 | 21 |
| 2015 May | 25 | 11 | 36 |
| 2015 April | 28 | 13 | 41 |
| 2015 March | 13 | 5 | 18 |
| 2015 February | 13 | 8 | 21 |
| 2015 January | 9 | 14 | 23 |
| 2014 December | 19 | 23 | 42 |
| 2014 November | 9 | 9 | 18 |
| 2014 October | 15 | 13 | 28 |
| 2014 September | 12 | 7 | 19 |
| 2014 August | 24 | 14 | 38 |
| 2014 July | 18 | 14 | 32 |
| 2014 June | 32 | 10 | 42 |
| 2014 May | 28 | 18 | 46 |
| 2014 April | 28 | 7 | 35 |
| 2014 March | 31 | 19 | 50 |
| 2014 February | 31 | 14 | 45 |
| 2014 January | 24 | 11 | 35 |
| 2013 December | 18 | 9 | 27 |
| 2013 November | 18 | 6 | 24 |
| 2013 October | 28 | 9 | 37 |
| 2013 September | 26 | 9 | 35 |
| 2013 August | 29 | 8 | 37 |
| 2013 July | 23 | 2 | 25 |
| 2013 June | 18 | 8 | 26 |
| 2013 May | 22 | 5 | 27 |
| 2013 April | 25 | 6 | 31 |
| 2013 March | 26 | 8 | 34 |
| 2013 February | 17 | 4 | 21 |
| 2013 January | 18 | 3 | 21 |
| 2012 December | 18 | 4 | 22 |
| 2012 November | 12 | 3 | 15 |
| 2012 October | 8 | 6 | 14 |
| 2012 September | 9 | 3 | 12 |
| 2012 May | 2 | 0 | 2 |
| 2012 April | 4 | 0 | 4 |
| 2012 March | 5 | 0 | 5 |
| 2012 February | 2 | 0 | 2 |
| 2012 January | 1 | 0 | 1 |
| 2011 December | 5 | 0 | 5 |
| 2011 November | 2 | 0 | 2 |
| 2011 October | 4 | 0 | 4 |
| 2011 June | 3 | 0 | 3 |
| 2011 May | 1 | 0 | 1 |
| 2011 April | 1 | 0 | 1 |
| 2011 March | 2 | 0 | 2 |
| 2011 February | 4 | 0 | 4 |
| 2011 January | 3 | 0 | 3 |
| 2010 December | 3 | 0 | 3 |
| 2010 November | 5 | 0 | 5 |
| 2010 October | 9 | 0 | 9 |
| 2010 September | 3 | 0 | 3 |
| 2010 August | 2 | 0 | 2 |
| 2010 July | 2 | 0 | 2 |
| 2010 May | 8 | 0 | 8 |
| 2010 April | 7 | 0 | 7 |
| 2010 March | 2 | 0 | 2 |
| 2010 February | 6 | 0 | 6 |
| 2010 January | 5 | 0 | 5 |
| 2009 December | 2 | 0 | 2 |
| 2009 November | 7 | 0 | 7 |
| 2009 October | 15 | 0 | 15 |
| 2009 September | 9 | 0 | 9 |
| 2009 August | 4 | 0 | 4 |
| 2009 July | 3 | 0 | 3 |
| 2009 June | 8 | 0 | 8 |
| 2009 May | 6 | 0 | 6 |
| 2009 April | 28 | 0 | 28 |
| 2009 March | 10 | 0 | 10 |
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