A study on the subjective compliance and acceptance of oral lanzoprazole in traumatology. The ECOFT-TR Study
Estudio sobre el cumplimiento subjetivo y la aceptabilidad de lansoprazol comprimidos bucodipersables en traumatología. Estudio ECOF-TR
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The ECOFT-TR Study" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "49" "paginaFinal" => "54" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Emilio Márquez-Contreras, Vicente Gil-Guillén, Albert Nadal-Sánchez, M. José Plazas-Fernández, Joan Heras-Navarro, Jordi Galván-Cervera, Joana Porcel-Carbonell" "autores" => array:7 [ 0 => array:4 [ "nombre" => "Emilio" "apellidos" => "Márquez-Contreras" "email" => array:1 [ 0 => "emarquezc@papps.org" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Vicente" "apellidos" => "Gil-Guillén" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "Albert" "apellidos" => "Nadal-Sánchez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "M." 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Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">e</span>" "identificador" => "aff0025" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Estudio sobre el cumplimiento subjetivo y la aceptabilidad de lansoprazol comprimidos bucodipersables en traumatología. Estudio ECOF-TR" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-05-15" "fechaAceptado" => "2008-06-27" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec112016" "palabras" => array:4 [ 0 => "Lansoprazolee" 1 => "Orally disintegrating tablets" 2 => "Acceptability" 3 => "Subjetive compliance" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec112017" "palabras" => array:4 [ 0 => "Lansoprazol" 1 => "Comprimidos bucodispersables" 2 => "Cumplimiento subjetivo" 3 => "Aceptabilidad" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To assess compliance with oral lansoprazolee disintegrating tablets (LODT) in patients treated by traumatology specialists.</p> <span class="elsevierStyleSectionTitle">Material and method</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A multicenter, observational, cross-sectional study involving 370 traumatology specialists and patients aged 18 or more. Study logistics were sponsored by Almirall Laboratories, S.A.; neither investigators nor patients received any economic compensation for their participation. Patient subjective compliance with LODT was assessed with the Haynes Sackett test. Acceptability was based on patients global assessments of the drug organoleptic characteristics and properties of use, and preferences regarding previous treatments, recorded by means of a self-administered 15-item ad hoc questionnaire with a 2–5-point Likert-type scale, that patients fulfilled once.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">One thousand and eighty five patients were analyzed for the main endpoint. Mean age was 56.09 (13.8) years; 56.77% were women. Mean treatment duration was 51.24 (38.8) days. 94.74% of the patients complied with the treatment. Mean percentage of compliance was 94.5 (12.12); 91.09% of patients rated the treatment as “acceptable or highly acceptable.” No significant differences were observed between compliant and non-compliant patients in terms of demographic or clinical variables. Mean percentage of compliance was significantly higher among patients without concomitant illness or treatment and without difficulties in taking tablets. One non-serious adverse reaction was reported in one (0.09%) patient.</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Compliance with lansoprazolee orally disintegrating tablets was high. Patients reported that this formulation improved their compliance and that they preferred LODT to previous medication. Tolerability was excellent.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Valorar el cumplimiento terapéutico con lansoprazol, comprimidos bucodispersables, en pacientes tratados por especialistas en traumatología.</p> <span class="elsevierStyleSectionTitle">Material y método</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Estudio observacional, transversal. Participaron 370 especialistas en traumatología que incluyeron a pacientes con un mínimo de 18 años. Los aspectos logísticos del estudio fueron financiados por Laboratorios Almirall, S.A.; los investigadores y pacientes no percibieron compensación alguna por su participación en el estudio. La valoración subjetiva del cumplimiento con lansoprazol comprimidos bucodispersables se realizó mediante el test de Haynes-Sackett. La aceptabilidad del tratamiento, considerada como la valoración general del paciente tras evaluar las características organolépticas y propiedades de uso, y su preferencia con respecto a tratamientos previos, se evaluó mediante un cuestionario ad hoc, autoaplicado, de 15 ítems con una escala tipo Likert con 2–5 posibles respuestas, que los pacientes cumplimentaron en una única ocasión.</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Fueron valorables 1.085 pacientes, con una media<span class="elsevierStyleHsp" style=""></span>±<span class="elsevierStyleHsp" style=""></span>desviación estándar de edad de 56,09<span class="elsevierStyleHsp" style=""></span>±<span class="elsevierStyleHsp" style=""></span>13,8 años; un 56,77% eran mujeres. La media de tiempo en tratamiento fue 51,24<span class="elsevierStyleHsp" style=""></span>±<span class="elsevierStyleHsp" style=""></span>38,8 días. El 94,74% de los pacientes cumplieron con el tratamiento. El grado medio de cumplimiento fue 94,5<span class="elsevierStyleHsp" style=""></span>±<span class="elsevierStyleHsp" style=""></span>12,12. El 91,09% de los pacientes calificó el tratamiento como «muy aceptable/aceptable». No hubo diferencias significativas en el porcentaje de pacientes cumplidores según las variables demográficas y clínicas. El grado o porcentaje de cumplimiento fue significativamente mejor entre los pacientes sin enfermedades y tratamientos concomitantes y sin dificultad en la toma de comprimidos. Para 1 (0,09%) paciente se notificó una reacción adversa no grave.</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">El cumplimiento con lansoprazol comprimidos bucodispersables fue muy elevado. Los pacientes valoraron que la formulación bucodispersable de lansoprazol les ayudaba a cumplir mejor con el tratamiento y lo prefirieron al que recibían previamente. La tolerabilidad fue excelente.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:25 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:1 [ "referenciaCompleta" => "Catálogo de especialidades, farmacéuticas. Consejo General de Colegios Oficiales de Farmacéuticos; 2000." ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Lansoprazole fast disgregating tablet: a new formulation for an established proton pump inhibitor" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "F. Baldi" 1 => "P. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 6 | 19 | 25 |
| 2024 October | 22 | 61 | 83 |
| 2024 September | 23 | 20 | 43 |
| 2024 August | 31 | 44 | 75 |
| 2024 July | 37 | 51 | 88 |
| 2024 June | 26 | 43 | 69 |
| 2024 May | 24 | 23 | 47 |
| 2024 April | 28 | 26 | 54 |
| 2024 March | 21 | 44 | 65 |
| 2024 February | 20 | 41 | 61 |
| 2024 January | 17 | 44 | 61 |
| 2023 December | 14 | 27 | 41 |
| 2023 November | 20 | 26 | 46 |
| 2023 October | 16 | 44 | 60 |
| 2023 September | 31 | 41 | 72 |
| 2023 August | 22 | 15 | 37 |
| 2023 July | 19 | 26 | 45 |
| 2023 June | 14 | 20 | 34 |
| 2023 May | 16 | 20 | 36 |
| 2023 April | 26 | 10 | 36 |
| 2023 March | 32 | 24 | 56 |
| 2023 February | 30 | 37 | 67 |
| 2023 January | 19 | 24 | 43 |
| 2022 December | 25 | 35 | 60 |
| 2022 November | 32 | 25 | 57 |
| 2022 October | 30 | 28 | 58 |
| 2022 September | 25 | 26 | 51 |
| 2022 August | 35 | 43 | 78 |
| 2022 July | 44 | 47 | 91 |
| 2022 June | 34 | 51 | 85 |
| 2022 May | 32 | 47 | 79 |
| 2022 April | 35 | 50 | 85 |
| 2022 March | 30 | 45 | 75 |
| 2022 February | 18 | 32 | 50 |
| 2022 January | 21 | 45 | 66 |
| 2021 December | 23 | 42 | 65 |
| 2021 November | 25 | 49 | 74 |
| 2021 October | 29 | 71 | 100 |
| 2021 September | 30 | 55 | 85 |
| 2021 August | 34 | 55 | 89 |
| 2021 July | 16 | 55 | 71 |
| 2021 June | 28 | 55 | 83 |
| 2021 May | 27 | 48 | 75 |
| 2021 April | 50 | 76 | 126 |
| 2021 March | 45 | 29 | 74 |
| 2021 February | 33 | 22 | 55 |
| 2021 January | 31 | 19 | 50 |
| 2020 December | 30 | 17 | 47 |
| 2020 November | 29 | 26 | 55 |
| 2020 October | 14 | 11 | 25 |
| 2020 September | 39 | 24 | 63 |
| 2020 August | 25 | 16 | 41 |
| 2020 July | 18 | 20 | 38 |
| 2020 June | 40 | 19 | 59 |
| 2020 May | 24 | 28 | 52 |
| 2020 April | 27 | 22 | 49 |
| 2020 March | 17 | 11 | 28 |
| 2020 February | 2 | 0 | 2 |
| 2020 January | 6 | 0 | 6 |
| 2019 September | 4 | 0 | 4 |
| 2019 August | 1 | 0 | 1 |
| 2019 June | 2 | 0 | 2 |
| 2019 March | 5 | 0 | 5 |
| 2019 January | 2 | 0 | 2 |
| 2018 December | 3 | 0 | 3 |
| 2018 May | 3 | 1 | 4 |
| 2018 April | 26 | 9 | 35 |
| 2018 March | 15 | 11 | 26 |
| 2018 February | 10 | 5 | 15 |
| 2018 January | 10 | 5 | 15 |
| 2017 December | 16 | 6 | 22 |
| 2017 November | 11 | 3 | 14 |
| 2017 October | 7 | 5 | 12 |
| 2017 September | 10 | 3 | 13 |
| 2017 August | 11 | 7 | 18 |
| 2017 July | 10 | 3 | 13 |
| 2017 June | 25 | 5 | 30 |
| 2017 May | 26 | 4 | 30 |
| 2017 April | 17 | 7 | 24 |
| 2017 March | 17 | 4 | 21 |
| 2017 February | 11 | 2 | 13 |
| 2017 January | 16 | 3 | 19 |
| 2016 December | 46 | 11 | 57 |
| 2016 November | 34 | 5 | 39 |
| 2016 October | 42 | 11 | 53 |
| 2016 September | 28 | 5 | 33 |
| 2016 August | 28 | 6 | 34 |
| 2016 July | 10 | 2 | 12 |
| 2016 March | 1 | 0 | 1 |
| 2016 February | 3 | 0 | 3 |
| 2015 December | 2 | 0 | 2 |
| 2015 November | 1 | 0 | 1 |
| 2015 September | 1 | 0 | 1 |
| 2015 August | 2 | 0 | 2 |
| 2015 July | 17 | 6 | 23 |
| 2015 June | 16 | 13 | 29 |
| 2015 May | 33 | 25 | 58 |
| 2015 April | 22 | 17 | 39 |
| 2015 March | 20 | 14 | 34 |
| 2015 February | 15 | 15 | 30 |
| 2015 January | 17 | 17 | 34 |
| 2014 December | 21 | 12 | 33 |
| 2014 November | 12 | 13 | 25 |
| 2014 October | 16 | 18 | 34 |
| 2014 September | 8 | 14 | 22 |
| 2014 August | 23 | 14 | 37 |
| 2014 July | 21 | 15 | 36 |
| 2014 June | 24 | 13 | 37 |
| 2014 May | 33 | 15 | 48 |
| 2014 April | 22 | 11 | 33 |
| 2014 March | 33 | 16 | 49 |
| 2014 February | 22 | 15 | 37 |
| 2014 January | 25 | 10 | 35 |
| 2013 December | 25 | 11 | 36 |
| 2013 November | 11 | 14 | 25 |
| 2013 October | 28 | 7 | 35 |
| 2013 September | 28 | 13 | 41 |
| 2013 August | 19 | 16 | 35 |
| 2013 July | 19 | 12 | 31 |
| 2013 June | 22 | 15 | 37 |
| 2013 May | 18 | 16 | 34 |
| 2013 April | 20 | 11 | 31 |
| 2013 March | 15 | 10 | 25 |
| 2013 February | 15 | 9 | 24 |
| 2013 January | 13 | 12 | 25 |
| 2012 December | 19 | 7 | 26 |
| 2012 November | 10 | 6 | 16 |
| 2012 October | 2 | 2 | 4 |
| 2012 September | 5 | 1 | 6 |
| 2012 June | 1 | 0 | 1 |
| 2012 May | 1 | 0 | 1 |
| 2012 April | 2 | 0 | 2 |
| 2012 March | 2 | 0 | 2 |
| 2012 February | 2 | 0 | 2 |
| 2012 January | 7 | 0 | 7 |
| 2011 December | 6 | 0 | 6 |
| 2011 November | 6 | 0 | 6 |
| 2011 October | 2 | 0 | 2 |
| 2011 July | 1 | 0 | 1 |
| 2011 June | 5 | 0 | 5 |
| 2011 May | 1 | 0 | 1 |
| 2011 March | 7 | 0 | 7 |
| 2011 February | 2 | 0 | 2 |
| 2011 January | 3 | 0 | 3 |
| 2010 December | 7 | 0 | 7 |
| 2010 November | 1 | 0 | 1 |
| 2010 October | 6 | 0 | 6 |
| 2010 September | 4 | 0 | 4 |
| 2010 August | 8 | 0 | 8 |
| 2010 July | 3 | 0 | 3 |
| 2010 June | 4 | 0 | 4 |
| 2010 May | 14 | 0 | 14 |
| 2010 April | 24 | 0 | 24 |
| 2010 March | 13 | 0 | 13 |
| 2010 February | 7 | 0 | 7 |
| 2010 January | 6 | 0 | 6 |
| 2009 December | 5 | 0 | 5 |
| 2009 November | 14 | 0 | 14 |
| 2009 October | 15 | 0 | 15 |
| 2009 September | 17 | 0 | 17 |
| 2009 August | 30 | 0 | 30 |
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