Measurement of health-related quality of life and functional capacity in patients with chronic tophaceous gout
Medición de la calidad de vida asociada a la salud y a la capacidad funcional en pacientes con gota crónica tofácea
Everardo Álvarez-Hernández
, Jorge A. Zamudio-Lerma, Gabriela Burgos-Martínez, Sandra E. Álvarez-Etchegaray, Ingris Peláez-Ballestas, J. Vázquez-Mellado
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Servicio de Reumatología, Hospital General de México, México D.F., Mexico
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Zamudio-Lerma, Gabriela Burgos-Martínez, Sandra E. Álvarez-Etchegaray, Ingris Peláez-Ballestas, J. Vázquez-Mellado" "autores" => array:6 [ 0 => array:4 [ "nombre" => "Everardo" "apellidos" => "Álvarez-Hernández" "email" => array:1 [ 0 => "everalvh@yahoo.com.mx" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Jorge A." "apellidos" => "Zamudio-Lerma" ] 2 => array:2 [ "nombre" => "Gabriela" "apellidos" => "Burgos-Martínez" ] 3 => array:2 [ "nombre" => "Sandra E." "apellidos" => "Álvarez-Etchegaray" ] 4 => array:2 [ "nombre" => "Ingris" "apellidos" => "Peláez-Ballestas" ] 5 => array:2 [ "nombre" => "J." "apellidos" => "Vázquez-Mellado" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Reumatología, Hospital General de México, México D.F., Mexico" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Medición de la calidad de vida asociada a la salud y a la capacidad funcional en pacientes con gota crónica tofácea" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-05-27" "fechaAceptado" => "2008-11-27" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec112079" "palabras" => array:3 [ 0 => "Tophaceus gout" 1 => "Health-related quality of life" 2 => "Functional capacity" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec112080" "palabras" => array:3 [ 0 => "Gota crónica tofácea" 1 => "Calidad de vida relacionada con la salud" 2 => "Capacidad funcional" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Introduction</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">In gout there are few instruments validated for the evaluation of activity, functional capacity, or quality of life. It is not known if generic instruments such as the MOS-20, or specific for other illnesses, such as the AIMS, can be applied to patients with gout.</p> <span class="elsevierStyleSectionTitle">Objective</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">To evaluate the clinimetric characteristic of the MOS-20 and AIMS questionnaires, and their correlation with HAQ-DI, as well as with clinical variables in patients with tophaceous gout (TG).</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Fortyy-nine patients with TG were included. Demographic and clinical variables were obtained. The 3 questionnaires were applied at the basal evaluation. A second evaluation was applied to 20 patients, 8 weeks later.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">All patients were male. The time of since onset of the illness was 14.9 (8.3) years. The HAQ-DI was 0.43 (0.56) with an alpha of Cronbach (αC) of 0.95 and the intraclass correlation coefficient (ICC) was 0.86. The MOS-20 had an αC of 0.68 to 1.0 and a ICC of 0.27 to 0.61 between the several components. The AIMS had an αC of 0.66 to 0.96, and a ICC of 0.11 to 0.79 between the several components. Reliability was better between the physical components in MOS-20 and AIMS. The MOS-20, AIMS and the HAQ-DI correlated with the presence of joints with functional limitation. There weren’t any significant differences among the patients with inflamed joints, nor in those with tophi. The HAQ-DI was best correlated with the physical component than with the mental component of the AIMS and the MOS-20.</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">The AIMS, the MOS-20 and the HAQ-DI are useful in measuring the functional capacity and the quality of life in patients with TG.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Introducción</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Hay pocos instrumentos en el estudio de gota validados para evaluar la actividad, la capacidad funcional o la calidad de vida de los pacientes. Se desconoce si los instrumentos genéricos como el cuestionario MOS-20 (Medical Outcomes Study Short Form Health Survey “Resultados médicos del formulario corto del estudio de la encuesta de salud”) o los instrumentos específicos para otras enfermedades, como el cuestionario AIMS (Arthritis Impact Measurement Scales “Escala de medición del impacto de la artritis”) puedan aplicarse a pacientes con gota.</p> <span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Evaluar las características clinimétricas de los cuestionarios MOS-20 y AIMS y su correlación con el cuestionario HAQ-DI (Health Assessment Questionnaire ‘Cuestionario de evaluación de salud’) así como con variables clínicas en los pacientes con gota crónica tofácea (GCT).</p> <span class="elsevierStyleSectionTitle">Pacientes y métodos</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Se incluyeron 49 pacientes con GCT. Se obtuvieron las variables demográficas y clínicas. Se aplicaron los 3 cuestionarios en la valoración basal. En 20 pacientes se realizó una segunda evaluación después de 8 semanas.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:20 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Gout and hiperuricemia" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "R.L. Wortmann" 1 => "W.N. Kelley" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "LibroEditado" => array:4 [ "titulo" => "Kelley's texbook of Rheumatology" "paginaInicial" => "1339" "paginaFinal" => "1376" "serieFecha" => "2000" ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib2" "etiqueta" => "2." 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 6 | 18 | 24 |
| 2024 October | 23 | 37 | 60 |
| 2024 September | 22 | 15 | 37 |
| 2024 August | 33 | 38 | 71 |
| 2024 July | 21 | 29 | 50 |
| 2024 June | 34 | 26 | 60 |
| 2024 May | 32 | 34 | 66 |
| 2024 April | 29 | 24 | 53 |
| 2024 March | 28 | 38 | 66 |
| 2024 February | 24 | 26 | 50 |
| 2024 January | 24 | 24 | 48 |
| 2023 December | 16 | 28 | 44 |
| 2023 November | 27 | 33 | 60 |
| 2023 October | 21 | 29 | 50 |
| 2023 September | 27 | 35 | 62 |
| 2023 August | 21 | 18 | 39 |
| 2023 July | 19 | 41 | 60 |
| 2023 June | 15 | 19 | 34 |
| 2023 May | 21 | 12 | 33 |
| 2023 April | 11 | 10 | 21 |
| 2023 March | 26 | 29 | 55 |
| 2023 February | 26 | 37 | 63 |
| 2023 January | 14 | 21 | 35 |
| 2022 December | 28 | 28 | 56 |
| 2022 November | 32 | 27 | 59 |
| 2022 October | 18 | 28 | 46 |
| 2022 September | 25 | 34 | 59 |
| 2022 August | 21 | 50 | 71 |
| 2022 July | 17 | 49 | 66 |
| 2022 June | 23 | 43 | 66 |
| 2022 May | 23 | 54 | 77 |
| 2022 April | 21 | 49 | 70 |
| 2022 March | 31 | 48 | 79 |
| 2022 February | 20 | 36 | 56 |
| 2022 January | 23 | 31 | 54 |
| 2021 December | 18 | 54 | 72 |
| 2021 November | 27 | 57 | 84 |
| 2021 October | 30 | 46 | 76 |
| 2021 September | 25 | 39 | 64 |
| 2021 August | 20 | 53 | 73 |
| 2021 July | 24 | 28 | 52 |
| 2021 June | 24 | 46 | 70 |
| 2021 May | 27 | 39 | 66 |
| 2021 April | 110 | 84 | 194 |
| 2021 March | 40 | 27 | 67 |
| 2021 February | 49 | 18 | 67 |
| 2021 January | 22 | 24 | 46 |
| 2020 December | 22 | 22 | 44 |
| 2020 November | 23 | 14 | 37 |
| 2020 October | 11 | 14 | 25 |
| 2020 September | 26 | 19 | 45 |
| 2020 August | 20 | 18 | 38 |
| 2020 July | 22 | 19 | 41 |
| 2020 June | 27 | 8 | 35 |
| 2020 May | 23 | 13 | 36 |
| 2020 April | 17 | 13 | 30 |
| 2020 March | 17 | 4 | 21 |
| 2020 February | 2 | 0 | 2 |
| 2020 January | 4 | 0 | 4 |
| 2019 September | 6 | 0 | 6 |
| 2019 June | 2 | 0 | 2 |
| 2019 March | 2 | 0 | 2 |
| 2019 January | 1 | 0 | 1 |
| 2018 May | 4 | 3 | 7 |
| 2018 April | 18 | 14 | 32 |
| 2018 March | 29 | 12 | 41 |
| 2018 February | 12 | 6 | 18 |
| 2018 January | 14 | 6 | 20 |
| 2017 December | 13 | 7 | 20 |
| 2017 November | 17 | 5 | 22 |
| 2017 October | 10 | 5 | 15 |
| 2017 September | 12 | 6 | 18 |
| 2017 August | 5 | 6 | 11 |
| 2017 July | 10 | 6 | 16 |
| 2017 June | 21 | 7 | 28 |
| 2017 May | 26 | 10 | 36 |
| 2017 April | 8 | 5 | 13 |
| 2017 March | 14 | 11 | 25 |
| 2017 February | 14 | 2 | 16 |
| 2017 January | 10 | 2 | 12 |
| 2016 December | 34 | 12 | 46 |
| 2016 November | 23 | 3 | 26 |
| 2016 October | 34 | 14 | 48 |
| 2016 September | 30 | 4 | 34 |
| 2016 August | 17 | 4 | 21 |
| 2016 July | 11 | 8 | 19 |
| 2016 January | 2 | 0 | 2 |
| 2015 December | 3 | 0 | 3 |
| 2015 October | 1 | 0 | 1 |
| 2015 September | 5 | 0 | 5 |
| 2015 July | 22 | 3 | 25 |
| 2015 June | 28 | 8 | 36 |
| 2015 May | 30 | 12 | 42 |
| 2015 April | 30 | 7 | 37 |
| 2015 March | 16 | 7 | 23 |
| 2015 February | 15 | 10 | 25 |
| 2015 January | 13 | 14 | 27 |
| 2014 December | 21 | 18 | 39 |
| 2014 November | 19 | 18 | 37 |
| 2014 October | 23 | 20 | 43 |
| 2014 September | 16 | 20 | 36 |
| 2014 August | 22 | 20 | 42 |
| 2014 July | 22 | 17 | 39 |
| 2014 June | 45 | 14 | 59 |
| 2014 May | 32 | 18 | 50 |
| 2014 April | 30 | 12 | 42 |
| 2014 March | 38 | 24 | 62 |
| 2014 February | 30 | 15 | 45 |
| 2014 January | 27 | 17 | 44 |
| 2013 December | 32 | 10 | 42 |
| 2013 November | 24 | 9 | 33 |
| 2013 October | 38 | 10 | 48 |
| 2013 September | 22 | 11 | 33 |
| 2013 August | 22 | 12 | 34 |
| 2013 July | 32 | 4 | 36 |
| 2013 June | 18 | 9 | 27 |
| 2013 May | 14 | 9 | 23 |
| 2013 April | 17 | 13 | 30 |
| 2013 March | 26 | 6 | 32 |
| 2013 February | 14 | 9 | 23 |
| 2013 January | 16 | 3 | 19 |
| 2012 December | 19 | 2 | 21 |
| 2012 November | 15 | 3 | 18 |
| 2012 October | 6 | 5 | 11 |
| 2012 September | 4 | 3 | 7 |
| 2012 May | 2 | 0 | 2 |
| 2012 April | 2 | 0 | 2 |
| 2012 March | 3 | 0 | 3 |
| 2012 February | 6 | 0 | 6 |
| 2012 January | 5 | 0 | 5 |
| 2011 December | 4 | 0 | 4 |
| 2011 November | 7 | 0 | 7 |
| 2011 October | 6 | 0 | 6 |
| 2011 September | 1 | 0 | 1 |
| 2011 August | 1 | 0 | 1 |
| 2011 June | 4 | 0 | 4 |
| 2011 May | 1 | 0 | 1 |
| 2011 April | 2 | 0 | 2 |
| 2011 March | 3 | 0 | 3 |
| 2011 February | 4 | 0 | 4 |
| 2011 January | 7 | 0 | 7 |
| 2010 December | 4 | 0 | 4 |
| 2010 November | 6 | 0 | 6 |
| 2010 October | 5 | 0 | 5 |
| 2010 September | 12 | 0 | 12 |
| 2010 August | 7 | 0 | 7 |
| 2010 July | 5 | 0 | 5 |
| 2010 June | 2 | 0 | 2 |
| 2010 May | 2 | 0 | 2 |
| 2010 April | 13 | 0 | 13 |
| 2010 March | 2 | 0 | 2 |
| 2010 February | 3 | 0 | 3 |
| 2010 January | 1 | 0 | 1 |
| 2009 December | 12 | 0 | 12 |
| 2009 November | 14 | 0 | 14 |
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