Can we see pain?
¿Se puede ver el dolor?
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New concepts" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "223" "paginaFinal" => "227" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Del edema de médula ósea a la osteonecrosis. Nuevos conceptos" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Guillermo Fernández-Cantón" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Guillermo" "apellidos" => "Fernández-Cantón" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217357430970125X?idApp=UINPBA00004M" "url" => "/21735743/0000000500000005/v1_201305061559/S217357430970125X/v1_201305061559/en/main.assets" ] "en" => array:15 [ "idiomaDefecto" => true "titulo" => "Can we see pain?" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "228" "paginaFinal" => "232" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "Joan Deus" "autores" => array:1 [ 0 => array:4 [ "nombre" => "Joan" "apellidos" => "Deus" "email" => array:1 [ 0 => "joan.deus@uab.cat" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Unidad de Investigación en RM, CRC-Hospital del Mar, Parc de Recerca Biomédica de Barcelona (PRBB), Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Departamento de Psicología Clínica y de la Salud, Universidad Autónoma de Barcelona, Barcelona, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "¿Se puede ver el dolor?" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-02-05" "fechaAceptado" => "2008-02-28" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec112201" "palabras" => array:5 [ 0 => "Functional neuroimaging" 1 => "Functional magnetic resonance imaging" 2 => "Neural system of pain" 3 => "Chronic pain" 4 => "Fibromyalgia" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec112202" "palabras" => array:5 [ 0 => "Neuroimagen funcional" 1 => "Resonancia magnética funcional" 2 => "Circuito neural del dolor" 3 => "Dolor crónico" 4 => "Fibromyalgia" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Pain is a highly subjective experience that is difficult to measure objectively due to its varied expression. It is defined as a complex sensory-emotional experience; it is modulated by cognitive factors and involves a broad neural system. Functional neuroimaging has helped to define that neural circuit involved in the perception, modulation and response to painful experience, both in healthy controls and in patients with acute and chronic pain disorders. However, functional activation of the so-called “pain matrix” may also be differentially modulated by sensory and emotional processing components. The latter, for example, can influence the intensity to which a stimulus is perceived as painful. Such a threshold seems to be lower in patients with clinical diagnosis of fibromyalgia (FM) and has been linked to an abnormal pattern of activation of the “pain matrix” when assessed with functional magnetic resonance imaging (fMRI), considering a “syndrome of central susceptibility.” Supporting an etiological explanation for FM, studies have noted that a significant proportion of patients with FM demonstrate this abnormal pattern of activation to stimuli of low intensity. Additionally, there is an important and significant temporal dimension to this activation pattern observed in FM patients, where areas commonly associated with the emotional experience of pain show a prolonged response to painful stimuli compared to healthy subjects. Accordingly, fMRI may assist in objectifying the experience of pain in patients with FM in response to nociceptive stimulation.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El dolor es una experiencia subjetiva difícilmente evaluable de forma objetiva por su variada expresión. Se define como una compleja experiencia sensorioemocional, modulada por factores cognitivos y que involucra un amplio sistema neural. La neuroimagen funcional ha contribuido a definir este circuito neural en controles sanos y en pacientes con un síndrome de dolor agudo o crónico implicado en la modulación, la percepción y la respuesta de una experiencia dolorosa. Sin embargo, la activación funcional de la “matriz neural” del dolor puede modularse, bien por un componente sensorial bien por un componente emocional. Este último podría mediatizar la intensidad apartir de la que un estímulo se percibe como doloroso. Este umbral parece ser menor en pacientes con diagnóstico clínico de fibromialgia (FM), pacientes que generan una anormal activación funcional del circuito neural del dolor, evaluada mediante resonancia magnética funcional (RMF), lo que se considera un síndrome de susceptibilidad central. En apoyo a esta explicación etiológica, los estudios de RMF constatan que una proporción significativa de pacientes con FM presenta una consistente y anormal activación de la “matriz neural” del dolor a estímulos de baja intensidad. Adicionalmente, se constata una importante y una significativa activación funcional con una duración temporal de activación cerebral superior a la del estímulo nociceptivo aplicado y, específicamente, en las áreas neuroanatómicas implicadas en la dimensión emocional del dolor. En consecuencia, la RMF permite observar, de manera incruenta, la anormal respuesta funcional cerebral a un estímulo nociceptivo en pacientes con diagnóstico clínico de FM.</p>" ] ] "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara">Accredited section by the SEAFORMEC with 11.9 credits. See questions from each article at <span class="elsevierStyleInterRef" href="http://www.reumatologiaclinica.org/">http://www.reumatologiaclinica.org</span>.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:29 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Neuroimaging: Visualizing the brain in pain" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:1 [ 0 => "A. 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| Year/Month | Html | Total | |
|---|---|---|---|
| 2024 November | 6 | 15 | 21 |
| 2024 October | 26 | 37 | 63 |
| 2024 September | 26 | 22 | 48 |
| 2024 August | 44 | 33 | 77 |
| 2024 July | 42 | 28 | 70 |
| 2024 June | 38 | 27 | 65 |
| 2024 May | 29 | 39 | 68 |
| 2024 April | 33 | 23 | 56 |
| 2024 March | 33 | 37 | 70 |
| 2024 February | 32 | 24 | 56 |
| 2024 January | 25 | 22 | 47 |
| 2023 December | 25 | 21 | 46 |
| 2023 November | 21 | 22 | 43 |
| 2023 October | 20 | 36 | 56 |
| 2023 September | 31 | 33 | 64 |
| 2023 August | 10 | 13 | 23 |
| 2023 July | 34 | 33 | 67 |
| 2023 June | 19 | 21 | 40 |
| 2023 May | 9 | 13 | 22 |
| 2023 April | 11 | 7 | 18 |
| 2023 March | 20 | 33 | 53 |
| 2023 February | 16 | 37 | 53 |
| 2023 January | 13 | 23 | 36 |
| 2022 December | 14 | 34 | 48 |
| 2022 November | 22 | 30 | 52 |
| 2022 October | 15 | 42 | 57 |
| 2022 September | 13 | 51 | 64 |
| 2022 August | 23 | 56 | 79 |
| 2022 July | 16 | 60 | 76 |
| 2022 June | 10 | 46 | 56 |
| 2022 May | 20 | 49 | 69 |
| 2022 April | 12 | 59 | 71 |
| 2022 March | 21 | 50 | 71 |
| 2022 February | 20 | 40 | 60 |
| 2022 January | 14 | 49 | 63 |
| 2021 December | 20 | 48 | 68 |
| 2021 November | 22 | 49 | 71 |
| 2021 October | 32 | 68 | 100 |
| 2021 September | 19 | 43 | 62 |
| 2021 August | 20 | 55 | 75 |
| 2021 July | 12 | 35 | 47 |
| 2021 June | 19 | 46 | 65 |
| 2021 May | 20 | 43 | 63 |
| 2021 April | 44 | 67 | 111 |
| 2021 March | 31 | 32 | 63 |
| 2021 February | 28 | 20 | 48 |
| 2021 January | 21 | 26 | 47 |
| 2020 December | 19 | 20 | 39 |
| 2020 November | 31 | 19 | 50 |
| 2020 October | 19 | 16 | 35 |
| 2020 September | 18 | 30 | 48 |
| 2020 August | 17 | 15 | 32 |
| 2020 July | 17 | 13 | 30 |
| 2020 June | 19 | 21 | 40 |
| 2020 May | 15 | 22 | 37 |
| 2020 April | 17 | 22 | 39 |
| 2020 March | 13 | 6 | 19 |
| 2020 February | 1 | 0 | 1 |
| 2019 June | 1 | 0 | 1 |
| 2019 March | 2 | 0 | 2 |
| 2018 May | 4 | 2 | 6 |
| 2018 April | 14 | 8 | 22 |
| 2018 March | 16 | 10 | 26 |
| 2018 February | 13 | 4 | 17 |
| 2018 January | 7 | 6 | 13 |
| 2017 December | 14 | 4 | 18 |
| 2017 November | 14 | 8 | 22 |
| 2017 October | 7 | 3 | 10 |
| 2017 September | 15 | 6 | 21 |
| 2017 August | 8 | 9 | 17 |
| 2017 July | 13 | 25 | 38 |
| 2017 June | 20 | 7 | 27 |
| 2017 May | 20 | 13 | 33 |
| 2017 April | 8 | 4 | 12 |
| 2017 March | 12 | 7 | 19 |
| 2017 February | 7 | 1 | 8 |
| 2017 January | 8 | 2 | 10 |
| 2016 December | 27 | 14 | 41 |
| 2016 November | 9 | 2 | 11 |
| 2016 October | 29 | 7 | 36 |
| 2016 September | 23 | 9 | 32 |
| 2016 August | 24 | 6 | 30 |
| 2016 July | 18 | 10 | 28 |
| 2016 May | 1 | 0 | 1 |
| 2016 April | 1 | 0 | 1 |
| 2016 February | 4 | 0 | 4 |
| 2016 January | 2 | 0 | 2 |
| 2015 December | 2 | 0 | 2 |
| 2015 October | 3 | 0 | 3 |
| 2015 September | 2 | 0 | 2 |
| 2015 July | 18 | 5 | 23 |
| 2015 June | 15 | 7 | 22 |
| 2015 May | 20 | 17 | 37 |
| 2015 April | 21 | 14 | 35 |
| 2015 March | 21 | 9 | 30 |
| 2015 February | 15 | 10 | 25 |
| 2015 January | 18 | 6 | 24 |
| 2014 December | 20 | 13 | 33 |
| 2014 November | 13 | 10 | 23 |
| 2014 October | 19 | 16 | 35 |
| 2014 September | 13 | 12 | 25 |
| 2014 August | 18 | 14 | 32 |
| 2014 July | 22 | 12 | 34 |
| 2014 June | 42 | 8 | 50 |
| 2014 May | 24 | 16 | 40 |
| 2014 April | 25 | 12 | 37 |
| 2014 March | 31 | 15 | 46 |
| 2014 February | 33 | 7 | 40 |
| 2014 January | 27 | 9 | 36 |
| 2013 December | 31 | 9 | 40 |
| 2013 November | 19 | 8 | 27 |
| 2013 October | 34 | 15 | 49 |
| 2013 September | 27 | 19 | 46 |
| 2013 August | 23 | 5 | 28 |
| 2013 July | 24 | 6 | 30 |
| 2013 June | 22 | 11 | 33 |
| 2013 May | 25 | 15 | 40 |
| 2013 April | 16 | 11 | 27 |
| 2013 March | 22 | 11 | 33 |
| 2013 February | 14 | 5 | 19 |
| 2013 January | 20 | 5 | 25 |
| 2012 December | 12 | 5 | 17 |
| 2012 November | 4 | 2 | 6 |
| 2012 October | 7 | 6 | 13 |
| 2012 September | 7 | 3 | 10 |
| 2012 June | 3 | 0 | 3 |
| 2012 April | 1 | 0 | 1 |
| 2012 March | 7 | 0 | 7 |
| 2012 February | 1 | 0 | 1 |
| 2012 January | 4 | 0 | 4 |
| 2011 December | 2 | 0 | 2 |
| 2011 November | 5 | 0 | 5 |
| 2011 October | 2 | 0 | 2 |
| 2011 September | 2 | 0 | 2 |
| 2011 August | 3 | 0 | 3 |
| 2011 July | 1 | 0 | 1 |
| 2011 June | 4 | 0 | 4 |
| 2011 May | 1 | 0 | 1 |
| 2011 April | 3 | 0 | 3 |
| 2011 March | 3 | 0 | 3 |
| 2011 February | 4 | 0 | 4 |
| 2011 January | 5 | 0 | 5 |
| 2010 December | 2 | 0 | 2 |
| 2010 November | 8 | 0 | 8 |
| 2010 October | 9 | 0 | 9 |
| 2010 September | 4 | 0 | 4 |
| 2010 July | 6 | 0 | 6 |
| 2010 May | 4 | 0 | 4 |
| 2010 April | 14 | 0 | 14 |
| 2010 March | 12 | 0 | 12 |
| 2010 February | 11 | 0 | 11 |
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