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Qualitative research study" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "16" "paginaFinal" => "22" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Fibromialgia: percepción de pacientes sobre su enfermedad y el sistema de salud. Estudio de investigación cualitativa" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "María José Escudero-Carretero, Noelia García-Toyos, María Ángeles Prieto-Rodríguez, Olivia Pérez-Corral, Joan Carles March-Cerdá, Manuela López-Doblas" "autores" => array:6 [ 0 => array:2 [ "nombre" => "María José" "apellidos" => "Escudero-Carretero" ] 1 => array:2 [ "nombre" => "Noelia" "apellidos" => "García-Toyos" ] 2 => array:2 [ "nombre" => "María Ángeles" "apellidos" => "Prieto-Rodríguez" ] 3 => array:2 [ "nombre" => "Olivia" "apellidos" => "Pérez-Corral" ] 4 => array:2 [ "nombre" => "Joan Carles" "apellidos" => "March-Cerdá" ] 5 => array:2 [ "nombre" => "Manuela" "apellidos" => "López-Doblas" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574310700058?idApp=UINPBA00004M" "url" => "/21735743/0000000600000001/v1_201305061603/S2173574310700058/v1_201305061603/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S2173574310700034" "issn" => "21735743" "doi" => "10.1016/S2173-5743(10)70003-4" "estado" => "S300" "fechaPublicacion" => "2010-01-01" "aid" => "70003" "copyright" => "Sociedad Española de Reumatología and Colegio Mexicano de Reumatología" "documento" => "article" "crossmark" => 0 "subdocumento" => "fla" "cita" => "Reumatol Clin. 2010;6:5-10" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 3070 "formatos" => array:3 [ "EPUB" => 43 "HTML" => 1499 "PDF" => 1528 ] ] "en" => array:10 [ "idiomaDefecto" => true "titulo" => "Hiperlaxity ligamentous (Beighton test) in the 8 to 12 years of age school population in the province of Granada" "tienePdf" => "en" "tieneTextoCompleto" => 0 "tieneResumen" => array:2 [ 0 => "en" 1 => "es" ] "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "5" "paginaFinal" => "10" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Hiperlaxitud ligamentosa (test de Beighton) en la población escolar de 8 a 12 aĩos de la provincia de Granada" ] ] "contieneResumen" => array:2 [ "en" => true "es" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Félix Zurita Ortega, Luis Ruiz Rodríguez, Asunción Martínez Martínez, Manuel Fernández Sánchez, Concepción Rodríguez Paiz, Remedios López Liriaa" "autores" => array:6 [ 0 => array:2 [ "nombre" => "Félix" "apellidos" => "Zurita Ortega" ] 1 => array:2 [ "nombre" => "Luis" "apellidos" => "Ruiz Rodríguez" ] 2 => array:2 [ "nombre" => "Asunción" "apellidos" => "Martínez Martínez" ] 3 => array:2 [ "nombre" => "Manuel" "apellidos" => "Fernández Sánchez" ] 4 => array:2 [ "nombre" => "Concepción" "apellidos" => "Rodríguez Paiz" ] 5 => array:2 [ "nombre" => "Remedios" "apellidos" => "López Liriaa" ] ] ] ] ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574310700034?idApp=UINPBA00004M" "url" => "/21735743/0000000600000001/v1_201305061603/S2173574310700034/v1_201305061603/en/main.assets" ] "en" => array:14 [ "idiomaDefecto" => true "titulo" => "Damage in Cuban patients with systemic lupus erythematosus. Relation with disease features" "tieneTextoCompleto" => 0 "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "11" "paginaFinal" => "15" ] ] "autores" => array:1 [ 0 => array:4 [ "autoresLista" => "Miguel Estévez del Toro, Araceli Chico Capote, Rafael Hechavarría, Rosa Jiménez Paneque, Elena Kokuina" "autores" => array:5 [ 0 => array:4 [ "nombre" => "Miguel" "apellidos" => "Estévez del Toro" "email" => array:1 [ 0 => "mestevez@infomed.sld.cu" ] "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:2 [ "nombre" => "Araceli" "apellidos" => "Chico Capote" ] 2 => array:2 [ "nombre" => "Rafael" "apellidos" => "Hechavarría" ] 3 => array:2 [ "nombre" => "Rosa" "apellidos" => "Jiménez Paneque" ] 4 => array:2 [ "nombre" => "Elena" "apellidos" => "Kokuina" ] ] "afiliaciones" => array:1 [ 0 => array:1 [ "entidad" => "Servicio de Reumatología, Hospital Hermanos Ameijeiras, Havana City, Cuba" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Daño en pacientes cubanos con lupus eritematoso sistémico. Relación con características de la enfermedad" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2008-09-05" "fechaAceptado" => "2009-04-27" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec112300" "palabras" => array:3 [ 0 => "Systemic lupus erythematosus" 1 => "Damage" 2 => "Damage predictor" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec112301" "palabras" => array:3 [ 0 => "Lupus eritematoso sistémico" 1 => "Daño" 2 => "Predictor de daño" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To determine damage presence and predictors factors for its appearance in a cohort of Cuban patients with systemic lupus erythematosus (SLE).</p> <span class="elsevierStyleSectionTitle">Patients and methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">A retrospective cohort study included 80 patients presenting with SLE seen in Rheumatology Service of “Hermanos Ameijeiras” Clinical Surgical Hospital in Havana City, Cuba. Damage was assessed using The Systemic Lupus International Collaborating Clinics/American College of Rheumatology (ACR) Damage Index (SLIC/ACR), a tool approved for damage measurement. Damage presence was related to initial disease features to diagnose this condition, to sociodemographic elements, to treatments used, and to the disease course time. Statistical analysis had two variants: the univariate and multivariate type using Chi2 and statistical significance was established in <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span><<span class="elsevierStyleHsp" style=""></span>.05.</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">We found that 39 patients (48.8%) had some degree of damage. More involved domains were the musculoskeletal (18.8%), neuropsychiatric, and skin, 16.3%, pulmonary and ocular, present in 15% of cases. In the multivariate analysis, damage was associated with the use of higher than 30<span class="elsevierStyleHsp" style=""></span>mg/day Prednisone doses for more of 4 weeks (OR=54.68, CI 95%=3.56–97.45, <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>.001), presence of leukopenia (RO=18.73, CI 95%=2.74–62.23 m <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>.004), and time course of disease (OR=1.02, CI 95%=1.00 2–1.09, <span class="elsevierStyleItalic">P</span><span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>.006).</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Damage was practically present in half of the study patients, the most involved domain was the musculoskeletal, and use of higher than 30<span class="elsevierStyleHsp" style=""></span>mg prednisone doses were the factor most associated with the presence of damage.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Determinar la presencia de daño y factores predictores de su aparición en una cohorte de pacientes cubanos con lupus eritematoso sistémico (LES).</p> <span class="elsevierStyleSectionTitle">Pacientes y método</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Se realizó un estudio de cohorte retrospectivo que incluyó a 80 pacientes con LES atendidos en el Servicio de Reumatología del Hospital Hermanos Ameijeiras en la ciudad de La Habana, Cuba. El daño fue determinado aplicando el Systemic Lupus International Collaborating Clinics/American College of Rheumatology (SLICC/ACR) Damage Index. La presencia de daño se relacionó con las características iniciales de la enfermedad al diagnóstico, con elementos sociodemográficos, con los tratamientos utilizados y con el tiempo de evolución de la enfermedad. El análisis estadístico incluyó estudios univariante y multivariado, y se utilizó el test de Chi-cuadrado (la significación estadística se fijó en p<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>0,05).</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Encontramos que 39 pacientes (48,8%) tenían algún grado de daño. Los dominios más afectados fueron el músculo esquelético (18,8%), el neuropsiquiátrico y la piel, ambos con un 16,3%. En el análisis multivariado el daño se asoció con la utilización de dosis de prednisona mayores de 30<span class="elsevierStyleHsp" style=""></span>mg diarios por más de cuatro semanas (OR = 54,68; IC 95%: 3,56–97,45; p<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>0,001), presencia de leucopenia (OR = 18,73; IC 95%: 2,74–62,23; p<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>0,004) y el tiempo mayor de evolución de la enfermedad (OR = 1,02; IC 95%:1,002–1,09; p<span class="elsevierStyleHsp" style=""></span>=<span class="elsevierStyleHsp" style=""></span>0,006).</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">El daño estuvo presente prácticamente en la mitad de los pacientes estudiados, el dominio más afectado fue el musculoesquelético y la utilización de dosis mayores a 30<span class="elsevierStyleHsp" style=""></span>mg de prednisona fue el factor más asociado con la presencia de daño.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:47 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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Year/Month | Html | Total | |
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2024 November | 4 | 16 | 20 |
2024 October | 30 | 38 | 68 |
2024 September | 26 | 21 | 47 |
2024 August | 34 | 37 | 71 |
2024 July | 30 | 48 | 78 |
2024 June | 22 | 40 | 62 |
2024 May | 27 | 55 | 82 |
2024 April | 23 | 31 | 54 |
2024 March | 29 | 39 | 68 |
2024 February | 21 | 33 | 54 |
2024 January | 24 | 32 | 56 |
2023 December | 10 | 23 | 33 |
2023 November | 35 | 45 | 80 |
2023 October | 27 | 41 | 68 |
2023 September | 26 | 151 | 177 |
2023 August | 21 | 17 | 38 |
2023 July | 25 | 40 | 65 |
2023 June | 12 | 22 | 34 |
2023 May | 24 | 24 | 48 |
2023 April | 11 | 13 | 24 |
2023 March | 22 | 29 | 51 |
2023 February | 22 | 32 | 54 |
2023 January | 28 | 39 | 67 |
2022 December | 20 | 28 | 48 |
2022 November | 22 | 31 | 53 |
2022 October | 28 | 30 | 58 |
2022 September | 19 | 30 | 49 |
2022 August | 20 | 44 | 64 |
2022 July | 26 | 50 | 76 |
2022 June | 18 | 39 | 57 |
2022 May | 34 | 51 | 85 |
2022 April | 36 | 44 | 80 |
2022 March | 31 | 50 | 81 |
2022 February | 17 | 30 | 47 |
2022 January | 19 | 29 | 48 |
2021 December | 14 | 51 | 65 |
2021 November | 23 | 45 | 68 |
2021 October | 34 | 44 | 78 |
2021 September | 22 | 39 | 61 |
2021 August | 22 | 40 | 62 |
2021 July | 22 | 32 | 54 |
2021 June | 10 | 36 | 46 |
2021 May | 35 | 28 | 63 |
2021 April | 65 | 74 | 139 |
2021 March | 37 | 26 | 63 |
2021 February | 42 | 26 | 68 |
2021 January | 23 | 23 | 46 |
2020 December | 26 | 17 | 43 |
2020 November | 25 | 21 | 46 |
2020 October | 16 | 13 | 29 |
2020 September | 33 | 16 | 49 |
2020 August | 24 | 16 | 40 |
2020 July | 19 | 13 | 32 |
2020 June | 27 | 18 | 45 |
2020 May | 19 | 10 | 29 |
2020 April | 25 | 19 | 44 |
2020 March | 20 | 10 | 30 |
2020 February | 1 | 0 | 1 |
2020 January | 4 | 0 | 4 |
2019 September | 4 | 0 | 4 |
2019 June | 1 | 0 | 1 |
2019 March | 2 | 0 | 2 |
2019 January | 1 | 0 | 1 |
2018 May | 4 | 2 | 6 |
2018 April | 19 | 7 | 26 |
2018 March | 23 | 14 | 37 |
2018 February | 12 | 8 | 20 |
2018 January | 8 | 11 | 19 |
2017 December | 9 | 8 | 17 |
2017 November | 9 | 13 | 22 |
2017 October | 19 | 5 | 24 |
2017 September | 12 | 5 | 17 |
2017 August | 8 | 7 | 15 |
2017 July | 19 | 10 | 29 |
2017 June | 23 | 15 | 38 |
2017 May | 34 | 19 | 53 |
2017 April | 17 | 11 | 28 |
2017 March | 17 | 39 | 56 |
2017 February | 10 | 2 | 12 |
2017 January | 11 | 6 | 17 |
2016 December | 31 | 14 | 45 |
2016 November | 21 | 5 | 26 |
2016 October | 36 | 6 | 42 |
2016 September | 32 | 7 | 39 |
2016 August | 24 | 8 | 32 |
2016 July | 10 | 1 | 11 |
2016 June | 0 | 11 | 11 |
2016 May | 0 | 14 | 14 |
2016 April | 0 | 13 | 13 |
2016 March | 0 | 16 | 16 |
2016 February | 3 | 0 | 3 |
2016 January | 2 | 17 | 19 |
2015 December | 3 | 0 | 3 |
2015 September | 1 | 0 | 1 |
2015 August | 4 | 0 | 4 |
2015 July | 12 | 4 | 16 |
2015 June | 21 | 9 | 30 |
2015 May | 59 | 25 | 84 |
2015 April | 21 | 13 | 34 |
2015 March | 14 | 13 | 27 |
2015 February | 25 | 10 | 35 |
2015 January | 25 | 17 | 42 |
2014 December | 31 | 20 | 51 |
2014 November | 10 | 13 | 23 |
2014 October | 17 | 14 | 31 |
2014 September | 10 | 14 | 24 |
2014 August | 21 | 16 | 37 |
2014 July | 16 | 21 | 37 |
2014 June | 38 | 12 | 50 |
2014 May | 28 | 18 | 46 |
2014 April | 25 | 19 | 44 |
2014 March | 39 | 21 | 60 |
2014 February | 24 | 14 | 38 |
2014 January | 28 | 16 | 44 |
2013 December | 21 | 12 | 33 |
2013 November | 28 | 14 | 42 |
2013 October | 33 | 21 | 54 |
2013 September | 25 | 17 | 42 |
2013 August | 22 | 12 | 34 |
2013 July | 25 | 5 | 30 |
2013 June | 27 | 18 | 45 |
2013 May | 31 | 15 | 46 |
2013 April | 32 | 18 | 50 |
2013 March | 21 | 22 | 43 |
2013 February | 13 | 14 | 27 |
2013 January | 18 | 13 | 31 |
2012 December | 11 | 14 | 25 |
2012 November | 12 | 15 | 27 |
2012 October | 4 | 6 | 10 |
2012 September | 8 | 3 | 11 |
2012 July | 1 | 0 | 1 |
2012 June | 1 | 0 | 1 |
2012 April | 3 | 0 | 3 |
2012 March | 4 | 0 | 4 |
2012 February | 2 | 0 | 2 |
2012 January | 4 | 0 | 4 |
2011 December | 2 | 0 | 2 |
2011 November | 4 | 0 | 4 |
2011 October | 3 | 0 | 3 |
2011 August | 2 | 0 | 2 |
2011 July | 2 | 0 | 2 |
2011 June | 3 | 0 | 3 |
2011 May | 2 | 0 | 2 |
2011 April | 1 | 0 | 1 |
2011 March | 3 | 0 | 3 |
2011 February | 3 | 0 | 3 |
2011 January | 5 | 0 | 5 |
2010 December | 7 | 0 | 7 |
2010 November | 4 | 0 | 4 |
2010 October | 6 | 0 | 6 |
2010 September | 1 | 0 | 1 |
2010 August | 13 | 0 | 13 |
2010 July | 11 | 0 | 11 |
2010 June | 9 | 0 | 9 |