Update of the Consensus Statement of the Spanish Society of Rheumatology on the management of biologic therapies in rheumatoid arthritis

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] 7 => array:3 [ "nombre" => "Juan" "apellidos" => "Gómez-Reino Carnota" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "h" "identificador" => "aff0040" ] ] ] 8 => array:3 [ "nombre" => "Luis" "apellidos" => "Carreño Pérez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "i" "identificador" => "aff0045" ] ] ] 9 => array:3 [ "nombre" => "Enrique" "apellidos" => "Batlle Gualda" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "j" "identificador" => "aff0050" ] ] ] 10 => array:3 [ "nombre" => "Alejandro" "apellidos" => "Balsa Criado" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "d" "identificador" => "aff0020" ] ] ] 11 => array:3 [ "nombre" => "José" "apellidos" => "Luis Andreu" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "k" "identificador" => "aff0055" ] ] ] 12 => array:3 [ "nombre" => "José" "apellidos" => "María Álvaro-Gracia" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "f" "identificador" => "aff0030" ] ] ] 13 => array:3 [ "nombre" => "Juan" "apellidos" => "Antonio Martínez López" "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "f" "identificador" => "aff0030" ] 1 => array:2 [ "etiqueta" => "l" "identificador" => "aff0060" ] ] ] 14 => array:4 [ "nombre" => "Estíbaliz" "apellidos" => "Loza Santamaría" "email" => array:1 [ 0 => "estibaliz.loza@ser.es" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "l" "identificador" => "aff0060" ] 1 => array:2 [ "etiqueta" => "¿" "identificador" => "cor0005" ] ] ] ] "afiliaciones" => array:12 [ 0 => array:3 [ "entidad" => "Servicio de Reumatología, Hospital General de Guadalajara, Guadalajara, Spain" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Reumatología, Hospital Clínic i Provincial, Barcelona, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Servicio de Reumatología, Hospital Marqués de Valdecilla, Santander, Spain" "etiqueta" => "c" "identificador" => "aff0015" ] 3 => array:3 [ "entidad" => "Servicio de Reumatología, Hospital La Paz, Madrid, Spain" "etiqueta" => "d" "identificador" => "aff0020" ] 4 => array:3 [ "entidad" => "Servicio de Reumatología, Hospital de Valme, Sevilla, Spain" "etiqueta" => "e" "identificador" => "aff0025" ] 5 => array:3 [ "entidad" => "Servicio de Reumatología, Hospital de la Princesa, Madrid, Spain" "etiqueta" => "f" "identificador" => "aff0030" ] 6 => array:3 [ "entidad" => "Servicio de Reumatología, Hospital Infanta Sofía, Madrid, Spain" "etiqueta" => "g" "identificador" => "aff0035" ] 7 => array:3 [ "entidad" => "Servicio de Reumatología, Hospital General de Santiago, Santiago de Compostela, A Coruña, Spain" "etiqueta" => "h" "identificador" => "aff0040" ] 8 => array:3 [ "entidad" => "Servicio de Reumatología, Hospital Gregorio Marañón, Madrid, Spain" "etiqueta" => "i" "identificador" => "aff0045" ] 9 => array:3 [ "entidad" => "Servicio de Reumatología, Hospital General de Alicante, Alicante, Spain" "etiqueta" => "j" "identificador" => "aff0050" ] 10 => array:3 [ "entidad" => "Servicio de Reumatología, Hospital Puerta de Hierro, Madrid, Spain" "etiqueta" => "k" "identificador" => "aff0055" ] 11 => array:3 [ "entidad" => "Unidad de Investigación, Sociedad Española de Reumatología, Madrid, Spain" "etiqueta" => "l" "identificador" => "aff0060" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Actualización del Documento de Consenso de la Sociedad Española de Reumatología sobre el uso de terapias biológicas en la artritis reumatoide" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-10-15" "fechaAceptado" => "2009-10-26" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec112313" "palabras" => array:5 [ 0 => "Consensos" 1 => "Recommendations" 2 => "Guidelines" 3 => "Biologic therapies" 4 => "Rheumatoid arthritis" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec112312" "palabras" => array:5 [ 0 => "Consenso" 1 => "Recomendaciones" 2 => "Guías" 3 => "Terapias biológicas" 4 => "Artritis reumatoide" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "ObjectiveTo provide a reference to rheumatologists and to those involved in the treatment of RA who are using, or about to use biologic therapy. MethodsRecommendations were developed following a nominal group methodology and based on systematic reviews. The level of evidence and grade of recommendation were classified according to the model proposed by the Center for Evidence Based Medicine at Oxford. The level of agreement was established through Delphi technique. ResultsWe have produced recommendations on the use of the seven biologic agents available for RA in our country. The objective of treatment is to achieve the remission of the disease as quickly as possible. Indications and nuances regarding the use of biologic therapy were reviewed as well as the evaluation that should be performed prior to administration and the follow up of patients undergoing this therapy. ConclusionsWe present an update on the SER recommendations for the use of biologic therapy in patients with RA." ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "ObjetivoServir de referencia para reumatólogos e implicados en el tratamiento de la artritis reumatoide que vayan a utilizar o consideren la utilización de terapias biológicas en su manejo. MétodosLas recomendaciones se emitieron siguiendo la metodología de grupos nominales y basadas en revisiones sistemáticas. El nivel de evidencia y el grado de recomendación se clasificaron según el modelo del Center for Evidence Based Medicine de Oxford y el grado de acuerdo se extrajo por técnica Delphi. ResultadosSe realizan recomendaciones sobre el uso de los siete agentes biológicos disponibles para la artritis reumatoide en la actualidad en nuestro país. El objetivo del tratamiento es lograr la remisión de la enfermedad lo más precozmente posible. Se revisan las indicaciones y matizaciones del uso de terapias biológicas y cuál debe ser la evaluación previa y la vigilancia del paciente con estos fármacos. ConclusionesSe presentan las actualizaciones a las recomendaciones SER para el uso de terapias biológicas en pacientes con artritis reumatoide." ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:111 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." 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Actualización del Documento de Consenso de la Sociedad Española de Reumatología sobre el uso de terapias biológicas en la artritis reumatoide

Jesús Tornero Molinaa, Raimon Sanmartí Salab, Vicente Rodríguez Valverdec, Emilio Martín Molad, José Luis Marenco de la Fuentee, Isidoro González Álvarof, Santiago Muñoz Fernándezg, Juan Gómez-Reino Carnotah, Luis Carreño Pérezi, Enrique Batlle Gualdaj, Alejandro Balsa Criadod, José Luis Andreuk, José María Álvaro-Graciaf, Juan Antonio Martínez Lópezf,l, Estíbaliz Loza Santamaríal,

Corresponding author

estibaliz.loza@ser.es

Corresponding author.

a Servicio de Reumatología, Hospital General de Guadalajara, Guadalajara, Spain

b Servicio de Reumatología, Hospital Clínic i Provincial, Barcelona, Spain

c Servicio de Reumatología, Hospital Marqués de Valdecilla, Santander, Spain

d Servicio de Reumatología, Hospital La Paz, Madrid, Spain

e Servicio de Reumatología, Hospital de Valme, Sevilla, Spain

f Servicio de Reumatología, Hospital de la Princesa, Madrid, Spain

g Servicio de Reumatología, Hospital Infanta Sofía, Madrid, Spain

h Servicio de Reumatología, Hospital General de Santiago, Santiago de Compostela, A Coruña, Spain

i Servicio de Reumatología, Hospital Gregorio Marañón, Madrid, Spain

j Servicio de Reumatología, Hospital General de Alicante, Alicante, Spain

k Servicio de Reumatología, Hospital Puerta de Hierro, Madrid, Spain

l Unidad de Investigación, Sociedad Española de Reumatología, Madrid, Spain

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        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To provide a reference to rheumatologists and to those involved in the treatment of RA who are using&#44; or about to use biologic therapy&#46;</p> <span class="elsevierStyleSectionTitle">Methods</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Recommendations were developed following a nominal group methodology and based on systematic reviews&#46; The level of evidence and grade of recommendation were classified according to the model proposed by the Center for Evidence Based Medicine at Oxford&#46; The level of agreement was established through Delphi technique&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">We have produced recommendations on the use of the seven biologic agents available for RA in our country&#46; The objective of treatment is to achieve the remission of the disease as quickly as possible&#46; Indications and nuances regarding the use of biologic therapy were reviewed as well as the evaluation that should be performed prior to administration and the follow up of patients undergoing this therapy&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">We present an update on the SER recommendations for the use of biologic therapy in patients with RA&#46;</p>"
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Article information

ISSN: 21735743
Original language: English

DOI:10.1016/S2173-5743(10)70006-X

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Year/Month	Html	Pdf	Total

2024 November	5	15	20
2024 October	28	70	98
2024 September	37	33	70
2024 August	49	56	105
2024 July	33	43	76
2024 June	47	44	91
2024 May	34	65	99
2024 April	28	48	76
2024 March	32	60	92
2024 February	36	60	96
2024 January	27	60	87
2023 December	30	57	87
2023 November	24	46	70
2023 October	36	69	105
2023 September	39	64	103
2023 August	38	44	82
2023 July	28	58	86
2023 June	23	45	68
2023 May	40	36	76
2023 April	25	30	55
2023 March	48	71	119
2023 February	28	65	93
2023 January	31	53	84
2022 December	41	50	91
2022 November	40	50	90
2022 October	40	61	101
2022 September	29	81	110
2022 August	58	85	143
2022 July	34	70	104
2022 June	59	61	120
2022 May	38	70	108
2022 April	39	48	87
2022 March	39	63	102
2022 February	39	36	75
2022 January	30	28	58
2021 December	24	42	66
2021 November	32	42	74
2021 October	40	54	94
2021 September	37	45	82
2021 August	39	39	78
2021 July	23	35	58
2021 June	33	49	82
2021 May	38	33	71
2021 April	41	71	112
2021 March	57	28	85
2021 February	46	21	67
2021 January	33	27	60
2020 December	42	19	61
2020 November	26	18	44
2020 October	16	13	29
2020 September	35	28	63
2020 August	22	19	41
2020 July	21	19	40
2020 June	40	20	60
2020 May	48	21	69
2020 April	29	15	44
2020 March	24	10	34
2020 February	1	0	1
2020 January	4	0	4
2019 September	3	0	3
2019 June	2	0	2
2019 March	2	0	2
2019 January	1	0	1
2018 May	4	1	5
2018 April	41	7	48
2018 March	36	14	50
2018 February	27	5	32
2018 January	22	4	26
2017 December	32	7	39
2017 November	21	5	26
2017 October	31	3	34
2017 September	23	16	39
2017 August	30	6	36
2017 July	23	8	31
2017 June	50	13	63
2017 May	52	9	61
2017 April	44	7	51
2017 March	40	16	56
2017 February	23	0	23
2017 January	32	2	34
2016 December	103	10	113
2016 November	74	4	78
2016 October	121	17	138
2016 September	81	8	89
2016 August	49	7	56
2016 July	30	5	35
2016 June	0	14	14
2016 May	1	12	13
2016 April	0	20	20
2016 March	0	22	22
2016 February	2	0	2
2016 January	2	13	15
2015 December	3	0	3
2015 September	1	0	1
2015 August	2	0	2
2015 July	17	4	21
2015 June	25	9	34
2015 May	62	16	78
2015 April	31	15	46
2015 March	24	9	33
2015 February	33	8	41
2015 January	40	7	47
2014 December	32	20	52
2014 November	22	8	30
2014 October	17	10	27
2014 September	16	9	25
2014 August	15	8	23
2014 July	27	11	38
2014 June	37	9	46
2014 May	37	15	52
2014 April	45	15	60
2014 March	43	18	61
2014 February	26	13	39
2014 January	28	15	43
2013 December	37	8	45
2013 November	26	6	32
2013 October	26	14	40
2013 September	43	12	55
2013 August	33	15	48
2013 July	28	7	35
2013 June	20	17	37
2013 May	25	13	38
2013 April	24	13	37
2013 March	15	11	26
2013 February	15	10	25
2013 January	17	6	23
2012 December	17	7	24
2012 November	15	4	19
2012 October	4	8	12
2012 September	5	3	8
2012 June	4	0	4
2012 April	6	0	6
2012 March	2	0	2
2012 February	4	0	4
2012 January	4	0	4
2011 December	1	0	1
2011 November	2	0	2
2011 October	4	0	4
2011 September	1	0	1
2011 August	1	0	1
2011 June	3	0	3
2011 May	5	0	5
2011 April	1	0	1
2011 March	6	0	6
2011 February	9	0	9
2011 January	21	0	21
2010 December	12	0	12
2010 November	8	0	8
2010 October	13	0	13
2010 September	3	0	3
2010 August	26	0	26
2010 July	20	0	20
2010 June	13	0	13

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