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Immunological techniques that support the diagnosis of the autoimmune diseases
Técnicas inmunológicas que apoyan el diagnóstico de las enfermedades autoinmunes
Diego F. Hernández Ramírez, Javier Cabiedes
Corresponding author
cabiedesj@yahoo.com

Corresponding author.
Laboratorio de Inmunología, Departamento de Inmunología y Reumatología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico
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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">During the past few years technological advance have been allowed the developing of techniques that help to the diagnosis of multiple diseases&#46; In the case of the autoimmune diseases&#44; immunological techniques are helpful since they allow the detection of multiple autoantibodies at the same time with small volumes of sample&#46; Together with the development of the new techniques&#44; sensitivity and specificity in the detection of the antibodies specificities&#8217; also have been increased&#44; in such a way that the clinicians can count with tests that allow them to make early diagnoses with greater certainty and also to follow the course of the disease based on the variation of the antibodies presents in the patient&#39;s samples&#46; It is important to emphasize that the new techniques of laboratory that are used for the support of the diagnosis of autoimmune diseases&#44; no longer are exclusive for research laboratories but by their facility of standardization&#44; quality control and reproducibility they can be used in clinical laboratory of medium and small sizes&#46; In the present paper we describe those techniques with greater application in the clinical laboratory of autoimmune diseases&#46;</p>"
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        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Durante los &#250;ltimos a&#241;os el avance tecnol&#243;gico ha permitido desarrollar t&#233;cnicas que ayudan al diagn&#243;stico de m&#250;ltiples enfermedades&#46; En el caso de las enfermedades autoinmunes&#44; las t&#233;cnicas inmunol&#243;gicas son de gran ayuda ya que permiten la detecci&#243;n de varios autoanticuerpos simult&#225;neamente a partir de vol&#250;menes de muestra peque&#241;os&#46; Aunado al desarrollo de las nuevas t&#233;cnicas&#44; la sensibilidad y especificidad en la detecci&#243;n de las especificidades de los anticuerpos tambi&#233;n han ido en aumento&#44; de tal manera que el cl&#237;nico puede contar con pruebas que le permiten hacer los diagn&#243;sticos tempranos con mayor certeza y hacer tambi&#233;n el seguimiento del curso de la enfermedad en funci&#243;n de la variaci&#243;n de los anticuerpos presentes en las muestras de los pacientes&#46; Cabe destacar que las nuevas t&#233;cnicas de laboratorio que se utilizan para el apoyo en el diagn&#243;stico de las enfermedades autoinmunes ya no son exclusivas de laboratorios de investigaci&#243;n&#44; sino que por su control de calidad&#44; facilidad de estandarizaci&#243;n y reproducibilidad pueden usarse en laboratorios cl&#237;nicos medianos y peque&#241;os&#46; En el presente trabajo se describen las t&#233;cnicas de mayor aplicaci&#243;n en el laboratorio cl&#237;nico para enfermedades autoinmunes&#46;</p>"
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ISSN: 21735743
Original language: English
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