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        "titulo" => "Abstract"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Sj&#246;gren&#39;s syndrome &#40;SS&#41; is an autoimmune disorder affecting primarily the exocrine glands&#44; leading to keratoconjunctivitis sicca &#40;KCS&#41; and xerostomia&#44; but that can also include extraglandular features1&#46; Due the anatomical&#44; physiological and pathological similarity between the pancreas and the salivary glands&#44; it has been described that the pancreas it is not exempt from the damage produced by this syndrome&#46; Some authors have assessed pancreatic involvement of SS by analyzing the histopathological changes&#44; evaluating the pancreatic endocrine and exocrine function &#40;serum pancreatic enzymes&#44; elastase&#44; lipase or trypsin determinations&#44; N-benzoyl-L-tyrosyl-para-aminobenzoic acid excretion test&#44; etc&#41;&#44; searching specific pancreatic antibodies &#40;antiductal&#41; or performing endoscopic retrograde colangiopancreatography or noninvasive imaging studies such as computed tomography or ultrasound&#46; Herein we review the literature regarding the prevalence and type of pancreatic involvement in the SS and we discuss the differential diagnosis with multiorganic Lymphoproliferative Syndrome&#46;</p>"
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        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El s&#237;ndrome de Sj&#246;gren &#40;SS&#41; es una enfermedad autoinmunitaria que afecta principalmente a las gl&#225;ndulas exocrinas&#44; aunque puede ocasionar tambi&#233;n manifestaciones extraglandulares&#46; Dada la similitud anat&#243;mica&#44; fisiol&#243;gica y patol&#243;gica del p&#225;ncreas y las gl&#225;ndulas salivales&#44; se ha descrito que el p&#225;ncreas no est&#225; exento del da&#241;o producido por el s&#237;ndrome de Sj&#246;gren&#46; Por esta similitud&#44; algunos autores han estudiado la influencia del SS en el p&#225;ncreas analizando los cambios histopatol&#243;gicos&#44; evaluando la funci&#243;n pancre&#225;tica endocrina y exocrina &#40;medici&#243;n de enzimas pancre&#225;ticas s&#233;ricas&#44; prueba de excreci&#243;n de &#225;cido N-benzoil-Ltirosil- para-aminobenzoico&#44; medici&#243;n de elastasa&#44; lipasa o tripsina&#41;&#44; por la detecci&#243;n de anticuerpos espec&#237;ficos para p&#225;ncreas &#40;Ac&#46; anticonductos&#41;&#44; o mediante la realizaci&#243;n de colangiopancreatograf&#237;a endosc&#243;pica retr&#243;grada o estudios de imagen no invasivos &#40;tomograf&#237;a computarizada y ultrasonido&#41;&#46; En el presente trabajo revisamos la literatura cient&#237;fica en relaci&#243;n con la prevalencia y el grado de afecci&#243;n pancre&#225;tica en SS y discutimos sobre el diagn&#243;stico diferencial con el s&#237;ndrome linfoproliferativo multiorg&#225;nico&#46;</p>"
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                      "titulo" => "Primary Sj&#246;gren&#39;s Syndrome&#58; current and emergent aetiopathogenic concepts"
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                        0 => array:2 [
                          "etal" => false
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                            1 => "J&#46; Font"
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                      "doi" => "10.1093/rheumatology/keh714"
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                            2 => "J&#46; Rosas"
                            3 => "M&#46; Camps"
                            4 => "A&#46; Gil"
                            5 => "J&#46; Del Pino-Montes"
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                      "titulo" => "A case of autoimmune pancreatitis associated with sclerosing cholangitis&#44; retroperitoneal fibrosis and Sj&#246;gren&#39;s syndrome"
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                          "etal" => true
                          "autores" => array:6 [
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                            2 => "H&#46; Yoshizawa"
                            3 => "S&#46; Ohashi"
                            4 => "H&#46; Tamaki"
                            5 => "K&#46; Kawasaki"
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                      "titulo" => "Systemic extrapancreatic lesions associated with autoimmune pancreatitis"
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                            0 => "H&#46; Ohara"
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                            2 => "H&#46; Sano"
                            3 => "T&#46; Ando"
                            4 => "T&#46; Okamoto"
                            5 => "H&#46; Takada"
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                            "web" => "Medline"
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                      "titulo" => "Overlap syndrome of autoimmune pancreatitis and cholangitis associated with secondary Sj&#246;gren&#39;s syndrome"
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                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
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                            2 => "H&#46; Lochs"
                            3 => "J&#46; Ockenga"
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Review
Sjögren's syndrome and pancreatic affection
Afección pancreática en el síndrome de Sjögren
Gabriela Hernández-Molina
Corresponding author
gabyhm@yahoo.com

Corresponding author.
, Martha L. Michel-Peregrina
Departamento de Inmunología y Reumatología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico
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        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">El s&#237;ndrome de Sj&#246;gren &#40;SS&#41; es una enfermedad autoinmunitaria que afecta principalmente a las gl&#225;ndulas exocrinas&#44; aunque puede ocasionar tambi&#233;n manifestaciones extraglandulares&#46; Dada la similitud anat&#243;mica&#44; fisiol&#243;gica y patol&#243;gica del p&#225;ncreas y las gl&#225;ndulas salivales&#44; se ha descrito que el p&#225;ncreas no est&#225; exento del da&#241;o producido por el s&#237;ndrome de Sj&#246;gren&#46; Por esta similitud&#44; algunos autores han estudiado la influencia del SS en el p&#225;ncreas analizando los cambios histopatol&#243;gicos&#44; evaluando la funci&#243;n pancre&#225;tica endocrina y exocrina &#40;medici&#243;n de enzimas pancre&#225;ticas s&#233;ricas&#44; prueba de excreci&#243;n de &#225;cido N-benzoil-Ltirosil- para-aminobenzoico&#44; medici&#243;n de elastasa&#44; lipasa o tripsina&#41;&#44; por la detecci&#243;n de anticuerpos espec&#237;ficos para p&#225;ncreas &#40;Ac&#46; anticonductos&#41;&#44; o mediante la realizaci&#243;n de colangiopancreatograf&#237;a endosc&#243;pica retr&#243;grada o estudios de imagen no invasivos &#40;tomograf&#237;a computarizada y ultrasonido&#41;&#46; En el presente trabajo revisamos la literatura cient&#237;fica en relaci&#243;n con la prevalencia y el grado de afecci&#243;n pancre&#225;tica en SS y discutimos sobre el diagn&#243;stico diferencial con el s&#237;ndrome linfoproliferativo multiorg&#225;nico&#46;</p>"
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                            1 => "L&#46; Dong"
                            2 => "N&#46; Kurose"
                            3 => "K&#46; Kitaggawa"
                            4 => "Y&#46; Morikawa"
                            5 => "M&#46; Yamamaoto"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/ard.2008.089169"
                      "Revista" => array:6 [
                        "tituloSerie" => "Ann Rheum Dis"
                        "fecha" => "2009"
                        "volumen" => "68"
                        "paginaInicial" => "1310"
                        "paginaFinal" => "1315"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18701557"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735743/0000000700000002/v1_201305061619/S2173574311700247/v1_201305061619/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "8381"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Review"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735743/0000000700000002/v1_201305061619/S2173574311700247/v1_201305061619/en/main.pdf?idApp=UINPBA00004M&text.app=https://reumatologiaclinica.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574311700247?idApp=UINPBA00004M"
]
Article information
ISSN: 21735743
Original language: English
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Idiomas
Reumatología Clínica (English Edition)
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