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        "titulo" => "Abstract"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The Catalan Agency for Health Technology Assessment and Research &#40;AETIM&#41; proposed&#44; in 2001&#44; criteria for performing a bone densitometry &#40;BD&#41; for use in the consultations of the public health system&#46;</p> <span class="elsevierStyleSectionTitle">Objective</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">To determine the sensitivity&#44; specificity&#44; positive predictive value and negative predictive value of the criteria to indicate BD&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Five groups of volunteers &#40;premenopausal women aged 46 to 65 years&#44; postmenopausal women aged 46 to 65 years&#44; postmenopausal women aged &#62;65 years and men 46 to 65 years and &#62;65 years&#41; underwent BD and a questionnaire on risk factors&#46; The results obtained with the AETIM criteria are related to criteria for indication of BD proposed by the World Health Organization &#40;1999 and 2003 criteria&#41;&#44; the National Osteoporosis Foundation &#40;1998 and 2010 criteria&#41; and the International Committee of Clinical Guidelines on Osteoporosis&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Criteria from the Catalan Agency have low sensitivity to detect both low bone mass &#40;T index &#60;&#8722;1&#41; and osteoporosis &#40;T index &#60;&#8722;2&#46;5&#41;&#44; specificity varied according to the group&#46; The positive predictive value is low&#44; but the negative predictive value for osteoporosis is high in all groups &#40;except for postmenopausal women aged &#62;65 years&#41;&#46; The remaining criteria have a high negative predictive value and&#44; in women&#44; good sensitivity and low specificity&#44; especially for identifying patients with osteoporosis&#46;</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Catalan Agency criteria are useful for selecting patients who would not need BD&#44; but lack sufficient sensitivity to identify individuals with low bone mass&#46; The other criteria also have a high negative predictive value for osteoporosis&#44; and a better sensitivity&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">La Agencia de Evaluaci&#243;n de Tecnolog&#237;as e Investigaci&#243;n M&#233;dicas &#40;AETIM&#41; de Catalu&#241;a propuso en 2001 unos criterios de indicaci&#243;n de densitometr&#237;a &#243;sea &#40;DO&#41; para su uso en las consultas del sistema sanitario p&#250;blico&#46; El objetivo fue conocer la sensibilidad&#44; la especificidad&#44; el valor predictivo positivo &#40;VPP&#41; y valor predictivo negativo &#40;VPN&#41; de los criterios de indicaci&#243;n de DO de la AETIM&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todo</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Cinco grupos de voluntarios &#40;mujeres premenop&#225;usicas de 46 a 65 a&#241;os&#44; posmenop&#225;usicas de 46 a 65 a&#241;os y posmenop&#225;usicas de &#62; 65 a&#241;os&#44; y varones de 46 a 65 a&#241;os y de &#62; 65 a&#241;os&#41; a los que se realiz&#243; DO y una encuesta sobre factores de riesgo&#46; Se calcularon la sensibilidad&#44; la especificidad&#44; el VPP y el VPN de los criterios de la AETIM&#44; y los resultados se compararon con los criterios de indicaci&#243;n de DO propuestos por la Organizaci&#243;n Mundial de la Salud &#40;en 1999 y 2003&#41;&#44; la National Osteoporosis Foundation &#40;en 1998 y 2010&#41; y el Comit&#233; Internacional de Gu&#237;as Cl&#237;nicas en Osteoporosis&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Los criterios de la AETIM tienen una baja sensibilidad tanto para detectar baja masa &#243;sea &#40;&#237;ndice T &#60; &#8722;1&#41; como osteoporosis &#40;&#237;ndice T &#60; &#8722;2&#44;5&#41;&#59; la especificidad var&#237;a seg&#250;n el grupo&#46; El VPP es bajo&#44; pero el VPN para osteoporosis es alto en todos los grupos &#40;excepto el de mujeres posmenop&#225;usicas &#62; 65 a&#241;os&#41;&#46; El resto de los criterios tienen un VPN alto y&#44; en mujeres&#44; buena sensibilidad y muy baja especificidad&#44; especialmente para identificar pacientes con osteoporosis&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Los criterios de la AETIM son &#250;tiles para seleccionar pacientes a los que no ser&#237;a necesario realizar una DO&#44; pero carecen de sensibilidad suficiente para identificar individuos con baja masa &#243;sea&#46; El resto de criterios tienen tambi&#233;n un VPN alto para osteoporosis y una sensibilidad algo mejor&#46;</p>"
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Original article
Sensitivity, specificity, positive and negative predictive values of the criteria for indicating a bone densitometry in the Evaluation of Medical Techniques and Research in Cataluña
Sensibilidad, especificidad y valor predictivo positive y negativo de los criterios de indicación de densitometría ósea de la Agencia de Evaluación de Tecnologías e Investigación Médicas de Cataluña
Daniel Roig Vilasecaa,
Corresponding author
26188drv@comb.cat

Corresponding author.
, Carles Valero Garcíab, M. Pilar Boncompte Vilanovac, Juli Muñoz Lópezc, Carme Contreras Garcíad, Montserrat Romera Baurése, on behalf of the densitometry referral study group
a Unitat de Reumatologia, Centre d’Atenció Especialitzada Cornellà, Servei d’Atenció Primària Baix Llobregat Centre, Cornellà de Llobregat, Barcelona, Spain
b Servei d’Atenció Primària Baix Llobregat Centre, Cornellà de Llobregat, Barcelona, Spain
c Àrea Bàsica de Salut Les Planes, Servei d’Atenció Primària Baix Llobregat Centre, Sant Joan Despí, Barcelona, Spain
d Àrea Bàsica de Salut Pubilla Cases, Servei d’Atenció Primària L’Hospitalet, L’Hospitalet de Llobregat, Barcelona, Spain
e Servei de Reumatologia, Hospital Universitari de Bellvitge (IDIBELL), L’Hospitalet de Llobregat, Barcelona, Spain
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        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">The Catalan Agency for Health Technology Assessment and Research &#40;AETIM&#41; proposed&#44; in 2001&#44; criteria for performing a bone densitometry &#40;BD&#41; for use in the consultations of the public health system&#46;</p> <span class="elsevierStyleSectionTitle">Objective</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">To determine the sensitivity&#44; specificity&#44; positive predictive value and negative predictive value of the criteria to indicate BD&#46;</p> <span class="elsevierStyleSectionTitle">Material and methods</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Five groups of volunteers &#40;premenopausal women aged 46 to 65 years&#44; postmenopausal women aged 46 to 65 years&#44; postmenopausal women aged &#62;65 years and men 46 to 65 years and &#62;65 years&#41; underwent BD and a questionnaire on risk factors&#46; The results obtained with the AETIM criteria are related to criteria for indication of BD proposed by the World Health Organization &#40;1999 and 2003 criteria&#41;&#44; the National Osteoporosis Foundation &#40;1998 and 2010 criteria&#41; and the International Committee of Clinical Guidelines on Osteoporosis&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Criteria from the Catalan Agency have low sensitivity to detect both low bone mass &#40;T index &#60;&#8722;1&#41; and osteoporosis &#40;T index &#60;&#8722;2&#46;5&#41;&#44; specificity varied according to the group&#46; The positive predictive value is low&#44; but the negative predictive value for osteoporosis is high in all groups &#40;except for postmenopausal women aged &#62;65 years&#41;&#46; The remaining criteria have a high negative predictive value and&#44; in women&#44; good sensitivity and low specificity&#44; especially for identifying patients with osteoporosis&#46;</p> <span class="elsevierStyleSectionTitle">Conclusion</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Catalan Agency criteria are useful for selecting patients who would not need BD&#44; but lack sufficient sensitivity to identify individuals with low bone mass&#46; The other criteria also have a high negative predictive value for osteoporosis&#44; and a better sensitivity&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">La Agencia de Evaluaci&#243;n de Tecnolog&#237;as e Investigaci&#243;n M&#233;dicas &#40;AETIM&#41; de Catalu&#241;a propuso en 2001 unos criterios de indicaci&#243;n de densitometr&#237;a &#243;sea &#40;DO&#41; para su uso en las consultas del sistema sanitario p&#250;blico&#46; El objetivo fue conocer la sensibilidad&#44; la especificidad&#44; el valor predictivo positivo &#40;VPP&#41; y valor predictivo negativo &#40;VPN&#41; de los criterios de indicaci&#243;n de DO de la AETIM&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todo</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Cinco grupos de voluntarios &#40;mujeres premenop&#225;usicas de 46 a 65 a&#241;os&#44; posmenop&#225;usicas de 46 a 65 a&#241;os y posmenop&#225;usicas de &#62; 65 a&#241;os&#44; y varones de 46 a 65 a&#241;os y de &#62; 65 a&#241;os&#41; a los que se realiz&#243; DO y una encuesta sobre factores de riesgo&#46; Se calcularon la sensibilidad&#44; la especificidad&#44; el VPP y el VPN de los criterios de la AETIM&#44; y los resultados se compararon con los criterios de indicaci&#243;n de DO propuestos por la Organizaci&#243;n Mundial de la Salud &#40;en 1999 y 2003&#41;&#44; la National Osteoporosis Foundation &#40;en 1998 y 2010&#41; y el Comit&#233; Internacional de Gu&#237;as Cl&#237;nicas en Osteoporosis&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Los criterios de la AETIM tienen una baja sensibilidad tanto para detectar baja masa &#243;sea &#40;&#237;ndice T &#60; &#8722;1&#41; como osteoporosis &#40;&#237;ndice T &#60; &#8722;2&#44;5&#41;&#59; la especificidad var&#237;a seg&#250;n el grupo&#46; El VPP es bajo&#44; pero el VPN para osteoporosis es alto en todos los grupos &#40;excepto el de mujeres posmenop&#225;usicas &#62; 65 a&#241;os&#41;&#46; El resto de los criterios tienen un VPN alto y&#44; en mujeres&#44; buena sensibilidad y muy baja especificidad&#44; especialmente para identificar pacientes con osteoporosis&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">Los criterios de la AETIM son &#250;tiles para seleccionar pacientes a los que no ser&#237;a necesario realizar una DO&#44; pero carecen de sensibilidad suficiente para identificar individuos con baja masa &#243;sea&#46; El resto de criterios tienen tambi&#233;n un VPN alto para osteoporosis y una sensibilidad algo mejor&#46;</p>"
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