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she was studied using positron emission tomography &#40;PET&#41; to identify a small nodule in the lateral and deep region of the left breast&#44; with pathology findings suggesting a metabolic origin &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#44; which led to an ultrasound-guided biopsy and a histological diagnosis of moderately differentiated infiltrating ductal carcinoma &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41;&#46; Hormonal treatment and lumpectomy of the nodule as well as left axillary lymphadenectomy was performed with a good outcome&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">The spine is the most common site of bone metastases&#59; it is estimated that about 10&#37; of cancer patients develop spinal metastases &#40;&#62;50&#37;<span class="elsevierStyleHsp" style=""></span>multilevel metastases&#41;&#44; especially associated to carcinoma of the breast&#44; prostate and lung&#46; While up to 36&#37; of spinal lesions may be asymptomatic&#44; low back pain secondary to a pathologic fracture is the predominant symptom&#46;<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;2</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">Occult breast cancer consists in the appearance of a metastatic axillary lymph node&#44; without a clinically and radiologically primary breast tumor&#59; this is rare&#44; and described in 0&#46;3&#37;&#8211;0&#46;8&#37; of all breast tumors&#46;<a class="elsevierStyleCrossRefs" href="#bib0015"><span class="elsevierStyleSup">3&#44;4</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">The first images&#44; during the initial approach&#44; are based on plain x rays&#46; However&#44; in most cases these findings are often nonspecific&#44; making the use of other complementary imaging tests such as GO&#44; CT&#44; MRI and PET for providing great help in determining the cause of vertebral involvement&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">5</span></a>Of these&#44; PET will identify lesions with an abnormal metabolism without an objective anatomic abnormality &#40;sensitivity 62&#37;&#8211;100&#37; and specificity 96&#37;&#8211;100&#37;&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">6</span></a> As for hidden breast cancer&#44; the detection of such small lesions allows for the diagnosis when other conventional imaging tests do not lead to identification&#46;<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">7&#44;8</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Ethical Responsibilities</span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Protection of people and animals</span><p id="par0025" class="elsevierStylePara elsevierViewall">The authors declare that this study did not perform experiments on humans or animals&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Data confidentiality</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors declare that they have followed the protocols of their workplace on the publication of data from patients&#44; and all patients included in the study have received sufficient information and gave written informed consent to participate in the study&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Right to privacy and informed consent</span><p id="par0035" class="elsevierStylePara elsevierViewall">The authors state that patient data does not appear in this article&#46;</p></span></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Disclosures</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors have no disclosures to make&#46;</p></span></span>"
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Images in Clinical Rheumatology
Lumbar Pain as the Single Manifestation of an Occult Breast Cancer. Usefulness of Positron Emission Tomography
Dolor lumbar como única manifestación de un cáncer oculto de mama, utilidad de la tomografía por emisión de positrones
Marco Aurelio Ramírez Huarangaa,
Corresponding author
hurauma@hotmail.com

Corresponding author.
, Verónica Salas Manzanedoa, Marcos Paulino Huertasa, Yolanda Torres Sousab, Claudia Carolina Ramos Rodríguezc
a Servicio de Reumatología, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
b Servicio de Radiología, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
c Servicio de Anatomía Patológica, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
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ISSN: 21735743
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