was read the article
array:24 [ "pii" => "S2173574314001762" "issn" => "21735743" "doi" => "10.1016/j.reumae.2014.12.002" "estado" => "S300" "fechaPublicacion" => "2015-05-01" "aid" => "733" "copyright" => "Elsevier España, S.L.U.. All rights reserved" "copyrightAnyo" => "2014" "documento" => "simple-article" "subdocumento" => "cor" "cita" => "Reumatol Clin. 2015;11:184" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1388 "formatos" => array:3 [ "EPUB" => 54 "HTML" => 1028 "PDF" => 306 ] ] "Traduccion" => array:1 [ "es" => array:19 [ "pii" => "S1699258X14002216" "issn" => "1699258X" "doi" => "10.1016/j.reuma.2014.10.010" "estado" => "S300" "fechaPublicacion" => "2015-05-01" "aid" => "733" "copyright" => "Elsevier España, S.L.U." "documento" => "simple-article" "crossmark" => 1 "subdocumento" => "cor" "cita" => "Reumatol Clin. 2015;11:184" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:2 [ "total" => 8760 "formatos" => array:3 [ "EPUB" => 155 "HTML" => 7389 "PDF" => 1216 ] ] "es" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Carta al Editor</span>" "titulo" => "Síndrome de fatiga crónica y sensibilidad al gluten no celíaca. Asociación o causa?" "tienePdf" => "es" "tieneTextoCompleto" => "es" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "184" ] ] "titulosAlternativos" => array:1 [ "en" => array:1 [ "titulo" => "Chronic fatigue syndrome and non-celiac gluten sensitivity. Association or cause?" ] ] "contieneTextoCompleto" => array:1 [ "es" => true ] "contienePdf" => array:1 [ "es" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Carlos Isasi Zaragozá" "autores" => array:1 [ 0 => array:2 [ "nombre" => "Carlos" "apellidos" => "Isasi Zaragozá" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2173574314001762" "doi" => "10.1016/j.reumae.2014.12.002" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574314001762?idApp=UINPBA00004M" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X14002216?idApp=UINPBA00004M" "url" => "/1699258X/0000001100000003/v2_201504190227/S1699258X14002216/v2_201504190227/es/main.assets" ] ] "itemSiguiente" => array:18 [ "pii" => "S217357431400166X" "issn" => "21735743" "doi" => "10.1016/j.reumae.2014.09.003" "estado" => "S300" "fechaPublicacion" => "2015-05-01" "aid" => "723" "copyright" => "Elsevier España, S.L.U." "documento" => "simple-article" "subdocumento" => "cor" "cita" => "Reumatol Clin. 2015;11:185" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1409 "formatos" => array:3 [ "EPUB" => 80 "HTML" => 948 "PDF" => 381 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Response to: Fibromyalgia and Chronic Fatigue Syndrome Caused by Non-celiac Gluten Sensitivity" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "185" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Respuesta a: Fibromialgia y fatiga crónica causada por sensibilidad al gluten no celíaca" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Rami Qanneta, Ramon Fontova, Antoni Castel" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Rami" "apellidos" => "Qanneta" ] 1 => array:2 [ "nombre" => "Ramon" "apellidos" => "Fontova" ] 2 => array:2 [ "nombre" => "Antoni" "apellidos" => "Castel" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S1699258X14002113" "doi" => "10.1016/j.reuma.2014.09.008" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X14002113?idApp=UINPBA00004M" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217357431400166X?idApp=UINPBA00004M" "url" => "/21735743/0000001100000003/v2_201505050301/S217357431400166X/v2_201505050301/en/main.assets" ] "itemAnterior" => array:18 [ "pii" => "S2173574314001786" "issn" => "21735743" "doi" => "10.1016/j.reumae.2014.12.004" "estado" => "S300" "fechaPublicacion" => "2015-05-01" "aid" => "713" "copyright" => "Elsevier España, S.L.U." "documento" => "article" "subdocumento" => "sco" "cita" => "Reumatol Clin. 2015;11:182-3" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1178 "formatos" => array:3 [ "EPUB" => 55 "HTML" => 893 "PDF" => 230 ] ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Images in Clinical Rheumatology</span>" "titulo" => "Ossifying Myositis of the Neck Muscles" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "182" "paginaFinal" => "183" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Miositis osificante en los músculos del cuello" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 800 "Ancho" => 995 "Tamanyo" => 67789 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Axial maximum intensity projection (MIP) showing abnormal linear calcification.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Anna Pàmies, Alex Samitier, Javier Rodríguez-Fernández, Ramon Fontova" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Anna" "apellidos" => "Pàmies" ] 1 => array:2 [ "nombre" => "Alex" "apellidos" => "Samitier" ] 2 => array:2 [ "nombre" => "Javier" "apellidos" => "Rodríguez-Fernández" ] 3 => array:2 [ "nombre" => "Ramon" "apellidos" => "Fontova" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S1699258X14001703" "doi" => "10.1016/j.reuma.2014.08.004" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X14001703?idApp=UINPBA00004M" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574314001786?idApp=UINPBA00004M" "url" => "/21735743/0000001100000003/v2_201505050301/S2173574314001786/v2_201505050301/en/main.assets" ] "asociados" => array:1 [ 0 => array:18 [ "pii" => "S217357431400166X" "issn" => "21735743" "doi" => "10.1016/j.reumae.2014.09.003" "estado" => "S300" "fechaPublicacion" => "2015-05-01" "aid" => "723" "copyright" => "Elsevier España, S.L.U." "documento" => "simple-article" "subdocumento" => "cor" "cita" => "Reumatol Clin. 2015;11:185" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 1409 "formatos" => array:3 [ "EPUB" => 80 "HTML" => 948 "PDF" => 381 ] ] "en" => array:10 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Response to: Fibromyalgia and Chronic Fatigue Syndrome Caused by Non-celiac Gluten Sensitivity" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "185" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Respuesta a: Fibromialgia y fatiga crónica causada por sensibilidad al gluten no celíaca" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Rami Qanneta, Ramon Fontova, Antoni Castel" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Rami" "apellidos" => "Qanneta" ] 1 => array:2 [ "nombre" => "Ramon" "apellidos" => "Fontova" ] 2 => array:2 [ "nombre" => "Antoni" "apellidos" => "Castel" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S1699258X14002113" "doi" => "10.1016/j.reuma.2014.09.008" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X14002113?idApp=UINPBA00004M" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S217357431400166X?idApp=UINPBA00004M" "url" => "/21735743/0000001100000003/v2_201505050301/S217357431400166X/v2_201505050301/en/main.assets" ] ] "en" => array:13 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>" "titulo" => "Chronic Fatigue Syndrome and Non-celiac Gluten Sensitivity. Association or Cause?" "tieneTextoCompleto" => true "saludo" => "To the editor:" "paginas" => array:1 [ 0 => array:1 [ "paginaInicial" => "184" ] ] "autores" => array:1 [ 0 => array:3 [ "autoresLista" => "Carlos Isasi Zaragozá" "autores" => array:1 [ 0 => array:3 [ "nombre" => "Carlos" "apellidos" => "Isasi Zaragozá" "email" => array:1 [ 0 => "cisasi.hpth@salud.madrid.org" ] ] ] "afiliaciones" => array:1 [ 0 => array:2 [ "entidad" => "Servicio de Reumatología, Hospital Puerta de Hierro, Majadahonda, Spain" "identificador" => "aff0005" ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Síndrome de fatiga crónica y sensibilidad al gluten no celíaca. ¿Asociación o causa?" ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">In their letter to the editor <span class="elsevierStyleItalic">Response to: Fibromyalgia and chronic fatigue caused by non-celiac gluten sensitivity</span>, Qanneta et al. pose a conceptual problem between the association of chronic fatigue syndrome (CFS) with non-celiac gluten sensitivity (SGNC) from the prevalent conception of considering chronic fatigue as a distinct disease. From this perspective, being chronic fatigue the central disease associated with other processes, they consider NCGS as a comorbid condition and not as an underlying cause.</p><p id="par0010" class="elsevierStylePara elsevierViewall">From my point of view fibromyalgia and chronic fatigue (FM/CFS) are not defined diseases but just syndromic terms that reflect reality. In the same way that diagnosing unexplained fever is no more than describing a clinical condition for which the cause of the fever is unknown, diagnosing FM/CFS is to describe a symptomatic set of unknown cause. Considering FM/CFS as defined diseases may even have negative effects, since the diagnosis seems to mean that the doctor knows what is happening to the patient, when I believe it is accepting a good deal of ignorance regarding the cause in the case of the physician and resignation in the case of the patient. I work based on the model considering FM/FC as a syndromic description. In this model, various more or less complex causes, which are probably interrelated, and that we are beginning to understand can produce the same clinical syndrome. Qanneta et al. proposes classifying CFS as pure and secondary.<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> I believe all CFS are secondary. NCGS of course does not explain all cases of FM/CFS, but it is an explanation for some of the patients. If the treatment of NCGS solves the FM/CFS syndrome, it may be reasonably said that the NCGS was the cause, especially if symptomatic recurrence occurs after ingesting gluten. There are other causes of FM/CFS different from NGCS which may not be detected using complementary explorations. For example, I have had patients in which the withdrawal of statins and psychotropic drugs formally resolved the symptoms of patients diagnosed with fibromyalgia. Even if the clinical manifestations have been resolved, one cannot say that “then the patient had no fibromyalgia,” as I do not think that the case presented had FM/CFS-like symptoms but in reality had no FM/CFS, as stated in their letter.</p><p id="par0015" class="elsevierStylePara elsevierViewall">Qanneta et al. refer poor experiences with GFD regarding systemic symptoms of patients with chronic fatigue. However we have observed a clear response of systemic symptoms, including mental fatigue, in fibromyalgia patients when treating NCGS. More than 30% of patients achieved remission of fibromyalgia or regained a normal life or went back to work or suspended treatment. The following case, treated during the preparation of this manuscript, illustrates this relationship: a 23 year old woman with 3 years since the onset of FM/CFS with severe fatigue that limited daily life activities, mental fatigue, generalized pain, headache, diarrhea and oral ulcers. She had been evaluated by gastroenterology, rheumatology, internal medicine and cardiology, with multiple studies that had ruled out pathology, including celiac disease. HLA typing showed DQ8 and the presence of duodenal biopsy showed type 1 Marsh enteropathy and intraepithelial lymphocytosis (29 CD3 lymphocytes per 100 enterocytes). After one year of follow-up, after starting diet without gluten or dairy, she presented complete remission of all her symptoms, with a normal life, practicing sports and without medication. She chose not to eat triggering foodstuffs.</p><p id="par0020" class="elsevierStylePara elsevierViewall">There may be several explanations for the observed different experience with the treatment of NCGS such as patient selection, time of treatment or the treatment modality of NGCS.</p><p id="par0025" class="elsevierStylePara elsevierViewall">In conclusion, we agree that the problem of FM/CFS is complex and requires multifactorial treatment, but there is a clear difference in perspective from which to address the problem. I prefer to dispense with the prevalent concept of FM/CFS as a disease, avoid the use of psychotropic drugs and seek causes that not show their faces in laboratory testing we usually perform.</p></span>" "pdfFichero" => "main.pdf" "tienePdf" => true "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Isasi Zaragozá C. Síndrome de fatiga crónica y sensibilidad al gluten no celíaca. ¿Asociación o causa? Reumatol Clin. 2015;11:184.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "Reference" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:1 [ 0 => array:3 [ "identificador" => "bib0005" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Tipología clínica del síndrome de fatiga crónica: hipótesis clasificatoria" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "R. Qanneta" 1 => "R. Fontova" 2 => "M.J. Poveda" 3 => "S. Castro" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1016/j.reuma.2013.04.004" "Revista" => array:6 [ "tituloSerie" => "Reumatol Clin" "fecha" => "2014" "volumen" => "10" "paginaInicial" => "132" "paginaFinal" => "133" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/23849741" "web" => "Medline" ] ] ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735743/0000001100000003/v2_201505050301/S2173574314001762/v2_201505050301/en/main.assets" "Apartado" => array:4 [ "identificador" => "8400" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Letters to the Editor" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735743/0000001100000003/v2_201505050301/S2173574314001762/v2_201505050301/en/main.pdf?idApp=UINPBA00004M&text.app=https://reumatologiaclinica.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574314001762?idApp=UINPBA00004M" ]
Year/Month | Html | Total | |
---|---|---|---|
2024 November | 12 | 10 | 22 |
2024 October | 44 | 39 | 83 |
2024 September | 75 | 13 | 88 |
2024 August | 93 | 36 | 129 |
2024 July | 77 | 32 | 109 |
2024 June | 103 | 45 | 148 |
2024 May | 101 | 31 | 132 |
2024 April | 81 | 25 | 106 |
2024 March | 88 | 29 | 117 |
2024 February | 50 | 25 | 75 |
2024 January | 45 | 16 | 61 |
2023 December | 59 | 27 | 86 |
2023 November | 52 | 31 | 83 |
2023 October | 62 | 37 | 99 |
2023 September | 73 | 25 | 98 |
2023 August | 52 | 11 | 63 |
2023 July | 79 | 25 | 104 |
2023 June | 59 | 27 | 86 |
2023 May | 60 | 20 | 80 |
2023 April | 45 | 17 | 62 |
2023 March | 66 | 25 | 91 |
2023 February | 59 | 30 | 89 |
2023 January | 64 | 27 | 91 |
2022 December | 58 | 43 | 101 |
2022 November | 89 | 29 | 118 |
2022 October | 73 | 47 | 120 |
2022 September | 62 | 36 | 98 |
2022 August | 62 | 44 | 106 |
2022 July | 59 | 43 | 102 |
2022 June | 69 | 29 | 98 |
2022 May | 84 | 42 | 126 |
2022 April | 74 | 47 | 121 |
2022 March | 101 | 46 | 147 |
2022 February | 102 | 33 | 135 |
2022 January | 78 | 38 | 116 |
2021 December | 58 | 41 | 99 |
2021 November | 73 | 51 | 124 |
2021 October | 68 | 47 | 115 |
2021 September | 62 | 40 | 102 |
2021 August | 68 | 44 | 112 |
2021 July | 56 | 33 | 89 |
2021 June | 73 | 46 | 119 |
2021 May | 81 | 38 | 119 |
2021 April | 180 | 108 | 288 |
2021 March | 91 | 32 | 123 |
2021 February | 79 | 29 | 108 |
2021 January | 57 | 23 | 80 |
2020 December | 65 | 38 | 103 |
2020 November | 78 | 21 | 99 |
2020 October | 54 | 13 | 67 |
2020 September | 108 | 32 | 140 |
2020 August | 54 | 23 | 77 |
2020 July | 52 | 21 | 73 |
2020 June | 66 | 30 | 96 |
2020 May | 55 | 22 | 77 |
2020 April | 45 | 28 | 73 |
2020 March | 22 | 10 | 32 |
2020 February | 1 | 0 | 1 |
2018 May | 5 | 0 | 5 |
2018 April | 39 | 10 | 49 |
2018 March | 62 | 7 | 69 |
2018 February | 29 | 3 | 32 |
2018 January | 41 | 9 | 50 |
2017 December | 27 | 6 | 33 |
2017 November | 26 | 9 | 35 |
2017 October | 35 | 7 | 42 |
2017 September | 34 | 3 | 37 |
2017 August | 20 | 12 | 32 |
2017 July | 31 | 10 | 41 |
2017 June | 38 | 19 | 57 |
2017 May | 56 | 15 | 71 |
2017 April | 30 | 8 | 38 |
2017 March | 19 | 4 | 23 |
2017 February | 18 | 6 | 24 |
2017 January | 31 | 4 | 35 |
2016 December | 55 | 18 | 73 |
2016 November | 49 | 3 | 52 |
2016 October | 68 | 10 | 78 |
2016 September | 64 | 11 | 75 |
2016 August | 55 | 6 | 61 |
2016 July | 26 | 8 | 34 |
2015 December | 2 | 0 | 2 |
2015 November | 1 | 21 | 22 |
2015 October | 1 | 22 | 23 |
2015 September | 3 | 0 | 3 |
2015 August | 1 | 22 | 23 |
2015 July | 24 | 10 | 34 |
2015 June | 67 | 21 | 88 |
2015 May | 70 | 22 | 92 |