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Las imágenes híbridas de SPECT/TC y reconstrucción 3<span class="elsevierStyleHsp" style=""></span>D (B) muestran actividad osteoblástica en epífisis de ambas tibias sin afectación de partes blandas adyacentes.</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Barbara Russo, Juan José Martin-Marcuartu, Alvaro de Bonilla-Damia, Rosario Garcia-Jimenez" "autores" => array:4 [ 0 => array:2 [ "nombre" => "Barbara" "apellidos" => "Russo" ] 1 => array:2 [ "nombre" => "Juan José" "apellidos" => "Martin-Marcuartu" ] 2 => array:2 [ "nombre" => "Alvaro" "apellidos" => "de Bonilla-Damia" ] 3 => array:2 [ "nombre" => "Rosario" "apellidos" => "Garcia-Jimenez" ] ] ] ] ] "idiomaDefecto" => "es" "Traduccion" => array:1 [ "en" => array:9 [ "pii" => "S2173574319300486" "doi" => "10.1016/j.reumae.2017.12.006" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "en" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574319300486?idApp=UINPBA00004M" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X17303121?idApp=UINPBA00004M" "url" => "/1699258X/0000001500000006/v1_201911200727/S1699258X17303121/v1_201911200727/es/main.assets" ] ] "itemSiguiente" => array:19 [ "pii" => "S2173574319300206" "issn" => "21735743" "doi" => "10.1016/j.reumae.2019.02.002" "estado" => "S300" "fechaPublicacion" => "2019-11-01" "aid" => "1163" "copyright" => "Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología" "documento" => "article" "crossmark" => 1 "subdocumento" => "sco" "cita" => "Reumatol Clin. 2019;15:e138-e139" "abierto" => array:3 [ "ES" => false "ES2" => false "LATM" => false ] "gratuito" => false "lecturas" => array:2 [ "total" => 2 "HTML" => 2 ] "en" => array:11 [ "idiomaDefecto" => true "cabecera" => "<span class="elsevierStyleTextfn">Images in Clinical Rheumatology</span>" "titulo" => "Digital Clubbing: A Patient With Hypertrophic Osteoarthropathy and the Presence of Acro-osteolysis" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "e138" "paginaFinal" => "e139" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Hipocratismo digital: paciente con osteoartropatía hipertrófica y presencia de acro-osteólisis" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0010" "etiqueta" => "Figure 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 1050 "Ancho" => 2000 "Tamanyo" => 149295 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">(A) Anteroposterior X-ray of both hands. Thickening of the soft tissues at the level of the distal fingers. Marked destructive changes with acro-osteolysis in all of the distal fingers (arrowed), with formation of flat surfaces in both the fifth fingers, bone proliferation at the level of the left radius and more discretely at the base of several distal fingers (arrow points). (B) Oblique X-ray of the right foot. 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"titulo" => "Double Cervical Rib: A Case Report" "tienePdf" => "en" "tieneTextoCompleto" => "en" "paginas" => array:1 [ 0 => array:2 [ "paginaInicial" => "370" "paginaFinal" => "371" ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Doble costilla cervical: a propósito de un caso" ] ] "contieneTextoCompleto" => array:1 [ "en" => true ] "contienePdf" => array:1 [ "en" => true ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1048 "Ancho" => 900 "Tamanyo" => 57790 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Proximal cervical rib (thin arrow) originating in vertebral body C3 (star) in a caudal direction and articulating with another distal supernumerary rib (thick arrow) originating and ascending from vertebral body C7 (arrow tip).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Nahia Plaza Aulestia, Sergio Rodríguez Montero, María Luisa Velloso Feijoo" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Nahia" "apellidos" => "Plaza Aulestia" ] 1 => array:2 [ "nombre" => "Sergio" "apellidos" => "Rodríguez Montero" ] 2 => array:2 [ "nombre" => "María Luisa" "apellidos" => "Velloso Feijoo" ] ] ] ] ] "idiomaDefecto" => "en" "Traduccion" => array:1 [ "es" => array:9 [ "pii" => "S1699258X17301754" "doi" => "10.1016/j.reuma.2017.06.015" "estado" => "S300" "subdocumento" => "" "abierto" => array:3 [ "ES" => true "ES2" => true "LATM" => true ] "gratuito" => true "lecturas" => array:1 [ "total" => 0 ] "idiomaDefecto" => "es" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X17301754?idApp=UINPBA00004M" ] ] "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574318301436?idApp=UINPBA00004M" 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array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 1 => array:2 [ "etiqueta" => "*" "identificador" => "cor0005" ] ] ] 2 => array:3 [ "nombre" => "Alvaro" "apellidos" => "de Bonilla-Damia" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 3 => array:3 [ "nombre" => "Rosario" "apellidos" => "Garcia-Jimenez" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] ] "afiliaciones" => array:2 [ 0 => array:3 [ "entidad" => "Servicio de Medicina Nuclear, Hospital Universitario Federico II, Naples, Italy" "etiqueta" => "a" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Servicio de Medicina Nuclear, Hospital Universitario Virgen del Rocío, Seville, Spain" "etiqueta" => "b" "identificador" => "aff0010" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Utilidad de las imágenes híbridas SPECT/TC en el infarto óseo" ] ] "resumenGrafico" => array:2 [ "original" => 0 "multimedia" => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1451 "Ancho" => 2551 "Tamanyo" => 169278 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">2-Stage scintigraphy (A) showing intense increased radiotracer uptake in the proximal thirds of the tibias. The hybrid SPECT/CT images and 3D reconstruction (B) show osteoblastic activity in the epiphysis of both tibias with no involvement of adjacent soft tissues.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 36-year-old male, amateur cyclist, presenting with intermittent pain in both knees of long duration. Physical examination found no signs of infection or inflammation. A radiograph was taken that showed no fracture lines, although serpiginous lesions were observed of oval-shaped morphology, and sclerotic borders in the proximal third of both tibias.</p><p id="par0010" class="elsevierStylePara elsevierViewall">A 2-stage scintigraphy was performed of both tibias after injection of 740<span class="elsevierStyleHsp" style=""></span>MBq 99mTc-hydroxymethylene biphosphonate. Increased radiotracer distribution was observed in the early images (5<span class="elsevierStyleHsp" style=""></span>min post injection) compatible with alteration of the vascular pool in the proximal thirds of both tibias (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A, arrow). In the later stage, 3<span class="elsevierStyleHsp" style=""></span>h post injection, bilateral and symmetrical deposition of biphosphonates were observed in both proximal tibial metaphyses (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>A, tips of arrow), which indicates increased osteoblastic activity at that level. We then performed hybrid SPECT/CT images, and 3D reconstruction (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>B), which enabled us to relate the increased radiotracer activity to certain regions of the sclerotic bone lesions that were metabolically active, and therefore with bone remodelling capacity, differentiating them from the regions that were necrotic. Moreover, no soft tissue involvement was seen on this study.<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">1</span></a></p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">Hybrid SPECT/TC images are useful in the suspicion of bone infarction since they increase the diagnostic precision of conventional scintigraphy and provide more precise information on the location and extension of the infarction, and on the possible involvement of adjacent soft tissue.<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">2</span></a> Hybrid SPECT/CT images also make it possible to distinguish necrotic tissue from tissue that is still viable,<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">3,4</span></a> enabling more individualised and targeted treatment.</p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Conflict of interests</span><p id="par0020" class="elsevierStylePara elsevierViewall">The authors have no conflict of interests to declare.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:2 [ 0 => array:2 [ "identificador" => "sec0005" "titulo" => "Conflict of interests" ] 1 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2017-08-21" "fechaAceptado" => "2017-12-19" "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Russo B, Martin-Marcuartu JJ, de Bonilla-Damia A, Garcia-Jimenez R. Utilidad de las imágenes híbridas SPECT/TC en el infarto óseo. Reumatol Clin. 2019;15:e136–e137.</p>" ] ] "multimedia" => array:1 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1451 "Ancho" => 2551 "Tamanyo" => 169278 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">2-Stage scintigraphy (A) showing intense increased radiotracer uptake in the proximal thirds of the tibias. The hybrid SPECT/CT images and 3D reconstruction (B) show osteoblastic activity in the epiphysis of both tibias with no involvement of adjacent soft tissues.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0015" "bibliografiaReferencia" => array:4 [ 0 => array:3 [ "identificador" => "bib0025" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Osteonecrosis of the jaw: more heat than light" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:3 [ 0 => "M. Pazianas" 1 => "R. Russell" 2 => "I. Fogelman" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2967/jnumed.108.057885" "Revista" => array:6 [ "tituloSerie" => "J Nucl Med" "fecha" => "2009" "volumen" => "50" "paginaInicial" => "6" "paginaFinal" => "7" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19091893" "web" => "Medline" ] ] ] ] ] ] ] ] 1 => array:3 [ "identificador" => "bib0030" "etiqueta" => "2" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A review on the clinical uses of SPECT/CT" "autores" => array:1 [ 0 => array:2 [ "etal" => true "autores" => array:6 [ 0 => "G. Mariani" 1 => "L. Bruselli" 2 => "T. Kuwert" 3 => "E. Kim" 4 => "A. Flotats" 5 => "O. Israel" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.1007/s00259-010-1390-8" "Revista" => array:6 [ "tituloSerie" => "Eur J Nucl Med Mol Imaging" "fecha" => "2010" "volumen" => "37" "paginaInicial" => "1959" "paginaFinal" => "1985" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20182712" "web" => "Medline" ] ] ] ] ] ] ] ] 2 => array:3 [ "identificador" => "bib0035" "etiqueta" => "3" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bone scintigraphy and SPECT/CT of bisphosphonate-induced osteonecrosis of the jaw" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:6 [ 0 => "F. Dore" 1 => "L. Filippi" 2 => "M. Biasotto" 3 => "S. Chiandussi" 4 => "F. Cavalli" 5 => "R. di Lenarda" ] ] ] ] ] "host" => array:1 [ 0 => array:2 [ "doi" => "10.2967/jnumed.107.048785" "Revista" => array:6 [ "tituloSerie" => "J Nucl Med" "fecha" => "2009" "volumen" => "50" "paginaInicial" => "30" "paginaFinal" => "35" "link" => array:1 [ 0 => array:2 [ "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19091894" "web" => "Medline" ] ] ] ] ] ] ] ] 3 => array:3 [ "identificador" => "bib0040" "etiqueta" => "4" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Bone infarcts: unsuspected gray areas?" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:2 [ 0 => "P. Lafforgue" 1 => "S. Trijau" ] ] ] ] ] "host" => array:1 [ 0 => array:1 [ "Revista" => array:5 [ "tituloSerie" => "Jt Bone Spine" "fecha" => "2016" "volumen" => "83" "paginaInicial" => "495" "paginaFinal" => "499" ] ] ] ] ] ] ] ] ] ] ] "idiomaDefecto" => "en" "url" => "/21735743/0000001500000006/v1_201911250632/S2173574319300486/v1_201911250632/en/main.assets" "Apartado" => array:4 [ "identificador" => "5795" "tipo" => "SECCION" "en" => array:2 [ "titulo" => "Images in Clinical Rheumatology" "idiomaDefecto" => true ] "idiomaDefecto" => "en" ] "PDF" => "https://static.elsevier.es/multimedia/21735743/0000001500000006/v1_201911250632/S2173574319300486/v1_201911250632/en/main.pdf?idApp=UINPBA00004M&text.app=https://reumatologiaclinica.org/" "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574319300486?idApp=UINPBA00004M" ]
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