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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Osteoporosis &#40;OP&#41; and fragility fractures are a public health problem due to the increase in morbidity and mortality that they generate&#46; Because prevalence of the disease is directly proportional to age&#44; OP is becoming increasingly frequent in a population that tends to live longer&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> However&#44; OP is not on the agenda of public health priorities in Colombia&#44; where other chronic diseases such as cancer&#44; HIV infection&#44; chronic kidney disease&#44; cardiovascular disease&#44; diabetes mellitus&#44; among others&#44; are the focus of the state budget and the interventions of health decision-makers&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> This paper aims to establish the prevalence of OP in Colombia&#44; describe the basic demographic characteristics of patients with this disease and give visibility to a problem that is silent but with multiple repercussions on our country&#8217;s health system&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Material and method</span><p id="par0010" class="elsevierStylePara elsevierViewall">A cross-sectional study was conducted based on official data from the Colombian Ministry of Health&#46; The official data from the Colombian Ministry of Health come from an information collection and storage tool called the Integral Social Protection Information System &#40;SISPRO&#41;&#44; which has four components&#58; health&#44; pensions&#44; occupational risks&#44; and social promotion&#46; The first component stores and processes the basic and minimum data required by the General System of Social Security in Health for management&#44; regulation&#44; and control processes&#46; This data is entered from the Individual Registry of Health Service Delivery&#46; The information contained in these databases is for public use&#46; The dynamic tables that the Ministry of Health has online were consulted and the data were obtained to conduct this study&#46; Information was obtained for Colombia for the period from 1 January 2012 to 31 December 2018&#44; for which an analysis of the Individual Registry of Health Service Delivery databases was undertaken&#44; using the international codes of diseases &#40;ICD-10&#41; for osteoporosis &#40;M800&#44; M801&#44; M802&#44; M803&#44; M804&#44; M805&#44; M808&#44; M809&#44; M810&#44; M811&#44; M812&#44; M813&#44; M814&#44; M815&#44; M818&#44; M819&#41;&#44; and we analysed variables such as sex&#44; type of insurance and distribution in five-year age groups&#44; according to the official projections of the National Administrative Department of Statistics&#44; based on the projections of the 2005 national census&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> The data collected were analysed with descriptive statistics&#44; using means and measures of central tendency for quantitative variables and proportions for qualitative variables&#46; Prevalence was adjusted by sex and age group to the 2015 population over 50 years of age&#44; projected for each of the 32 departments during the period analysed&#46; The diagnostic criteria for OP in the SISPRO database are not standardised&#59; they depend on the clinical and diagnostic judgement of each physician when registering a patient with an ICD-10 code related to OP&#46; Patients who were registered with a diagnosis of OP as the &#8220;principal diagnosis&#8221; were included&#46; It is important to highlight that the coverage of the Colombian health system is one of the highest in Latin America &#40;95&#46;1&#37;&#41;&#44;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> which allows for a significant amount of data from the entire population of the country&#46; This project was approved by our institution&#8217;s Central Research Committee&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Results</span><p id="par0015" class="elsevierStylePara elsevierViewall">We identified 249&#44;803 cases &#40;&#8220;persons attended&#8221;&#41; with a principal diagnosis of OP&#44; which allowed us to calculate an unadjusted prevalence of 2440 cases per 100&#44;000 inhabitants over 50 years of age&#44; and to establish that the condition is more frequent in women &#40;92&#37; of cases&#41;&#44; with a female&#58; male ratio of 12&#46;3&#58;1&#46; An analysis of the prevalence of OP by five-year age groups shows an increase in prevalence as the population ages &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a> and <a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; The number of patients according to sex and age group is presented in <a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#46; It can be observed that the prevalence of OP is higher in women &#40;4210 per 100&#44;000 inhabitants&#41; compared to men &#40;395 per 100&#44;000 inhabitants&#41;&#44; and that prevalence increases as the population ages&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">We also analysed the presence of OP with fractures&#44; which corresponded to 18&#37; of the total cases of osteoporosis&#46; Due to the characteristics of the Registry&#44; it was not possible to establish the fracture site&#46; In the analysis by sex&#44; we observed that 22&#37; of men with OP have fractures compared to 18&#37; of women&#46; Given these results&#44; we undertook an analysis of the prevalence of OP with fracture adjusted for sex and age&#44; which showed that the prevalence of OP with fracture is 1&#37; in women and &#46;1&#37; in men&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Regarding the distribution of OP by department&#44; we found that the national population-adjusted prevalence in men ranged between 2&#46;3 and 206&#46;2 per 100&#44;000 inhabitants&#44; while the adjusted prevalence in women was between 12 and 2190 per 100&#44;000 inhabitants &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; The areas with the highest adjusted prevalence in both men and women are three departments of the coffee-growing region&#58; Risaralda &#40;6&#46;8 per 100&#44;000 inhabitants&#41;&#44; Antioquia &#40;6&#46;2 per 100&#44;000 inhabitants&#41; and Caldas &#40;5&#46;8 per 100&#44;000 inhabitants&#41;&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Discussion</span><p id="par0030" class="elsevierStylePara elsevierViewall">Colombia is in a process of demographic transition&#44; as are other countries in the region&#44; due to increased longevity of the population&#46; Life expectancy according to the WHO for Colombia is 77 years&#44; and when differentiated by sex&#44; it is 80 years for women and 74 years for men&#46;<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">5&#44;6</span></a> One of the notable consequences of this demographic phenomenon is an increase in the prevalence of chronic non-communicable diseases&#46; This phenomenon has been documented worldwide in the case of OP&#44; which is a disease considered a public health problem because it affects postmenopausal women and the elderly population&#44; increasing the risk and incidence of fractures&#44; with significant social and economic costs for health systems&#46;<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">7&#44;8</span></a> It is estimated that approximately 200 million people suffer from OP worldwide&#44; with a progressive increase associated with the global ageing of the population&#44; although the prevalence of OP is difficult to establish&#44; given its asymptomatic course until the onset of fractures&#46;<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">7&#8211;9</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">According to the projections of the International Osteoporosis Foundation&#8217;s report presented in 2012&#44; it was evident that the data in Latin America were insufficient&#44; but the estimates indicated that there were 1&#44;423&#44;559 women with OP in Colombia and 8000&#8211;10&#44;000 hip fractures per year&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> However&#44; the data obtained from the Ministry of Health registry reports only 249&#44;803 people with OP&#44; which is one-fifth of the estimate of the International Osteoporosis Foundation&#46; Other work such as that by Morales-Torres et al&#46; collected data from Latin America&#44; where the range of vertebral OP was 7&#46;6&#37;&#8211;12&#46;1&#37; and of femoral neck OP was 7&#46;9&#37;&#8211;22&#37;&#44;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> which again is higher than that found in our study&#44; where the overall prevalence is 2&#46;4&#37; in those over 50 years of age&#46; A report from Bogota in 1999 reported a prevalence of OP of 32&#37; in a group of patients who underwent bone scans&#44;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> which again contrasts with the findings of the national registry&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">The results of this study show that OP occurs more frequently in women of all age ranges and its prevalence increases in a directly proportional manner&#44; which is in line with that reported in other studies in Latin America &#40;LAVOS&#44; Brazil&#41;<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">11&#44;12</span></a> and in other regions &#40;Spain&#44; China&#44; Canada&#41;&#46;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">13&#8211;15</span></a> However&#44; the lower prevalence than that reported in other studies may be due to under-diagnosis and under-recording in the SISPRO information system&#44; as well as the difference in the methodology of the studies&#44; since the methodology used to measure prevalence in the studies that we took as the reference for this article&#8217;s discussion was taking densitometry measurements of specific population groups using the active search mode&#44; or by analysing hospital records in at-risk populations&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">In terms of the prevalence of OP fractures&#44; these are two to three times more common in women&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">16</span></a> Worldwide&#44; about 8&#46;9 million fractures per year are attributable to OP&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">16</span></a> However&#44; there is likely to be under-reporting&#44; because some fragility fractures are under-diagnosed and under-treated&#44;<a class="elsevierStyleCrossRefs" href="#bib0085"><span class="elsevierStyleSup">17&#44;18</span></a> leading to the functional impairment of sufferers&#44; decreased quality of life and high mortality rates&#46;<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">11&#44;16</span></a> In 2010&#44; around 3&#46;5 million fractures in Europe were attributed to OP&#44; hip fracture being the most frequent&#46;<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">19</span></a> The LAVOS study&#44; conducted in 5 Latin American countries &#40;Argentina&#44; Brazil&#44; Colombia&#44; Mexico and Puerto Rico&#41; showed a standardised prevalence of vertebral fractures in women over 50 years of age of 11&#46;18&#37; &#40;95&#37; CI 9&#46;23&#8211;13&#46;4&#41;&#44; which increases from 6&#46;9&#37; in women aged 50&#8211;59 years to 27&#46;8&#37; in women over 80 years&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">12</span></a> This direct relationship between ageing and increased prevalence of fractures is also determined by the findings of our study&#44; as is the higher prevalence of OP among women&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">The Colombian health system is based on single-payer public financing and mixed public and private provision&#44; with almost universal coverage &#40;95&#46;1&#37; according to the latest official measurement in June 2019&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> However&#44; the main limitation of this study is underreporting&#44; due to the characteristics of the Registry&#44; which only records the main diagnoses&#44; not comorbidities&#44; which in the case of OP&#44; as it is often a comorbidity&#44; is not adequately recorded&#46; Neither is it possible to calculate the incidence because there is no criterion to determine the &#8220;main diagnosis&#8221; from one year to another&#46; As there can be variations in recording&#44; it is not possible to calculate the incidence or duration of the disease&#46;<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">20</span></a> Also&#44; due to the nature of the data&#44; it is not possible to establish the course of the disease&#44; the patients&#8217; specific clinical characteristics&#44; fracture sites&#44; or response to treatment&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">Our study shows information taken from the Colombian Ministry of Health database&#46; From this information we made demographic and epidemiological analyses of the population and projections for the care of patients with OP in our country&#46; These results alert us to the importance of improving the characteristics of the Registry&#44; and of designing public health policies for a disease which is possibly being under-diagnosed and therefore&#44; with a lower rate of treatment for patients&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Conflict of interests</span><p id="par0060" class="elsevierStylePara elsevierViewall">The authors have no conflict of interests to declare&#46;</p></span></span>"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Introduction</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Osteoporosis is considered a healthcare problem due to the increased risk of fractures and high cost of care&#46; In Colombia&#44; the Ministry of Health introduced SISPRO&#44; a tool to collect nationwide information from the health system&#46; The information collected from SISPRO is available for scientific analysis&#46; This article presents an analysis of the prevalence and characteristics of patients with osteoporosis using data from 2012 to 2018&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Aim</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">To estimate prevalence of osteoporosis between January 2012 to December 2018 and describe the patients&#8217; demographic characteristics&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Methods</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">This is a descriptive epidemiological study using the International Statistical Classification of Diseases and Related Health Problems related to osteoporosis as search terms using the SISPRO database&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Results</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">National records report 249&#44;803 patients over 50 years old diagnosed with osteoporosis&#46; The estimated prevalence is 2440 cases per 100&#44;000 inhabitants over 50 years old &#40;based on a total population of 10&#44;236&#44;132&#41;&#44; being more frequent in women &#40;92&#37; of cases&#41;&#44; with a female&#47;male ratio of 12&#46;3&#58;1&#46;</p></span> <span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Conclusion</span><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">This study shows a lower prevalence than previous estimates or projections&#46; Given these findings we think it is necessary to act to promote health policies for patients with osteoporosis&#46;</p></span>"
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        "resumen" => "<span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Introducci&#243;n</span><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">La osteoporosis es considerada un problema de salud p&#250;blica&#44; ya que&#44; al aumentar el riesgo de fracturas&#44; genera un alto coste para el sistema de salud&#46; En Colombia&#44; el Ministerio de Salud utiliza la herramienta SISPRO para recolectar informaci&#243;n del sistema de salud&#46; La informaci&#243;n almacenada en SISPRO es p&#250;blica y disponible para la investigaci&#243;n&#46; Este art&#237;culo presenta un an&#225;lisis de la prevalencia y caracter&#237;sticas de los pacientes con osteoporosis a partir de los datos del 2012 al 2018&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Objetivos</span><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Estimar la prevalencia de osteoporosis entre enero de 2012 a diciembre de 2018 y describir las caracter&#237;sticas demogr&#225;ficas de los pacientes&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">M&#233;todos</span><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Estudio descriptivo de corte transversal en el que se tomaron los datos de SISPRO&#44; utilizando como palabras clave los diagn&#243;sticos del manual internacional de enfermedades relacionados con el diagn&#243;stico de osteoporosis&#46;</p></span> <span id="abst0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Resultados</span><p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Se documentaron 249&#46;803 individuos mayores de 50 a&#241;os con diagn&#243;stico de osteoporosis&#44; estimando una prevalencia de 2&#46;440 casos por 100&#46;000 habitantes mayores de 50 a&#241;os &#40;basado en una poblaci&#243;n total de 10&#46;236&#46;132&#41;&#44; siendo m&#225;s frecuente en mujeres &#40;92&#37;&#41;&#44; con una relaci&#243;n mujer a hombre de 12&#44;3&#58;1&#46;</p></span> <span id="abst0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Conclusi&#243;n</span><p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">Este estudio muestra una baja prevalencia respecto a las estimaciones y proyecciones&#46; Dados estos resultados es necesario trabajar en promover pol&#237;ticas en salud para los pacientes con osteoporosis&#46;</p></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Fern&#225;ndez-&#193;vila DG&#44; Bernal-Mac&#237;as S&#44; Parra MJ&#44; Rinc&#243;n DN&#44; Guti&#233;rrez JM&#44; Rosselli D&#46; Prevalencia de osteoporosis en Colombia&#58; datos del registro nacional de salud del 2012 al 2018&#46; Reumatol Clin&#46; 2021&#59;17&#58;570&#8211;574&#46;</p>"
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          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Geographical distribution of the prevalence of osteoporosis for the period 2012&#8211;2018&#44; adjusting for sex and age group of the Columbian population&#46; Prevalence is calculated with the mean population of the period as the denominator per 100&#44;000 inhabitants&#46; &#40;A&#41; Males&#46; &#40;B&#41; Females&#46;</p>"
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                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Age group&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">2012&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">2013&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">2014&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">2015&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">2016&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">2017&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">2018&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Total patients&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Prevalence&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th></tr></thead><tbody title="tbody"><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">50&#8211;54&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;050&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;208&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;623&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;638&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1&#44;608&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;275&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;313&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#44;217&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">381&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">55&#8211;59&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;786&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;135&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;404&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;234&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;545&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#44;481&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#44;638&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">24&#44;571&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">1107&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">60&#8211;64&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;453&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;894&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#44;573&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#44;267&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#44;025&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">10&#44;916&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&#44;059&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">37&#44;910&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;193&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">65&#8211;69&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#44;471&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#44;895&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#44;665&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#44;820&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#44;485&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">12&#44;779&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">14&#44;973&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">43&#44;954&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">3&#44;362&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">70&#8211;74&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#44;660&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#44;853&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#44;172&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#44;150&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">8&#44;748&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11&#44;638&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&#44;546&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">40&#44;570&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">4&#44;377&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">75&#8211;79&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#44;854&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#44;716&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#44;879&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">6&#44;701&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">7&#44;194&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">9&#44;769&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">11&#44;130&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">35&#44;206&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">5&#44;142&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr><tr title="table-row"><td class="td-with-role" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t ; entry_with_role_rowhead " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">80 or more&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td><td class="td" title="\n
                  \t\t\t\t\ttable-entry\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t">13&#44;067&nbsp;\t\t\t\t\t\t\n
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                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2753051.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Patients seen with a primary diagnosis of osteoporosis by age group between 2012 and 2018&#46;</p>"
        ]
      ]
      3 => array:8 [
        "identificador" => "tbl0010"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
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        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0020"
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        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">COL&#58; Colombia&#59; OP&#58; osteoporosis&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
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                  \t\t\t\t" scope="col">&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " colspan="5" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Males</th><th class="td" title="\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Females</th></tr><tr title="table-row"><th class="td" title="\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Age group&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Males with OP&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Prevalence of OP &#40;&#215;100&#44;000 inhab&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Males with fractures and OP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">OP with fractures &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Prevalence of OP with fractures in COL &#40;&#215;100&#44;000 inhab&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Females with OP&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Prevalence of OP &#40;&#215;100&#44;000 inhab&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Females with fractures and OP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">OP with fractures &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Prevalence of OP with fractures in COL &#40;&#215;100&#44;000 inhab&#41;&nbsp;\t\t\t\t\t\t\n
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          "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Patients diagnosed with osteoporosis by sex and age group between 2012 and 2018&#46;</p>"
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                  ]
                ]
              ]
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              "etiqueta" => "9"
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                      "autores" => array:1 [
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                          "etal" => false
                          "autores" => array:3 [
                            0 => "L&#46; Alonso Gonz&#225;lez"
                            1 => "G&#46; Mar&#237;a V&#225;squez"
                            2 => "J&#46; Fernando Molina"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Colomb Reumatol"
                        "fecha" => "2009"
                        "volumen" => "16"
                        "paginaInicial" => "61"
                        "paginaFinal" => "75"
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib0050"
              "etiqueta" => "10"
              "referencia" => array:1 [
                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Densitometria &#243;sea&#58; utilidad diagn&#243;stica"
                      "autores" => array:1 [
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                          "etal" => false
                          "autores" => array:1 [
                            0 => "A&#46; P&#225;ez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev del Hosp Cent la Polic&#237;a Nac"
                        "fecha" => "1999"
                        "volumen" => "2"
                        "paginaInicial" => "27"
                        "paginaFinal" => "31"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "11"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The burden of osteoporosis in Brazil"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "B&#46;C&#46;G&#46; Marinho"
                            1 => "L&#46;P&#46; Guerra"
                            2 => "J&#46;B&#46; Drummond"
                            3 => "B&#46;C&#46; Silva"
                            4 => "M&#46;M&#46;S&#46; Soares"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1590/0004-2730000003203"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arq Bras Endocrinol Metabol"
                        "fecha" => "2014"
                        "volumen" => "58"
                        "paginaInicial" => "434"
                        "paginaFinal" => "443"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25166033"
                            "web" => "Medline"
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                      ]
                    ]
                  ]
                ]
              ]
            ]
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                    0 => array:2 [
                      "doi" => "10.1007/s00198-008-0657-4"
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                        "volumen" => "20"
                        "paginaInicial" => "275"
                        "paginaFinal" => "282"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18584111"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib0065"
              "etiqueta" => "13"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The population-based prevalence of osteoporotic vertebral fracture and densitometric osteoporosis in postmenopausal women over 50 in Valencia&#44; Spain &#40;the FRAVO study&#41;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
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                            1 => "B&#46; Reig-Molla"
                            2 => "G&#46; Sanf&#233;lix-Gimeno"
                            3 => "S&#46; Peir&#243;"
                            4 => "M&#46; Graells-Ferrer"
                            5 => "M&#46; Vega-Mart&#237;nez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
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                        "volumen" => "47"
                        "paginaInicial" => "610"
                        "paginaFinal" => "616"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20601286"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Osteoporosis in China"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "Y&#46; Wang"
                            1 => "Y&#46; Tao"
                            2 => "M&#46;E&#46; Hyman"
                            3 => "J&#46; Li"
                            4 => "Y&#46; Chen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00198-009-0925-y"
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                        "tituloSerie" => "Osteoporos Int"
                        "fecha" => "2009"
                        "volumen" => "20"
                        "paginaInicial" => "1651"
                        "paginaFinal" => "1662"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19415374"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The burden of illness of osteoporosis in Canada"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;E&#46; Tarride"
                            1 => "R&#46;B&#46; Hopkins"
                            2 => "W&#46;D&#46; Leslie"
                            3 => "S&#46; Morin"
                            4 => "J&#46;D&#46; Adachi"
                            5 => "A&#46; Papaioannou"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Osteoporos Int"
                        "fecha" => "2012"
                        "volumen" => "23"
                        "paginaInicial" => "2591"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An estimate of the worldwide prevalence and disability associated with osteoporotic fractures"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "O&#46; Johnell"
                            1 => "J&#46;A&#46; Kanis"
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                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00198-006-0172-4"
                      "Revista" => array:6 [
                        "tituloSerie" => "Osteoporos Int"
                        "fecha" => "2006"
                        "volumen" => "17"
                        "paginaInicial" => "1726"
                        "paginaFinal" => "1733"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16983459"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Treatment of osteoporosis&#58; are physicians missing an opportunity&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "K&#46;B&#46; Freedman"
                            1 => "F&#46;S&#46; Kaplan"
                            2 => "W&#46;B&#46; Bikler"
                            3 => "B&#46;L&#46; Strom"
                            4 => "R&#46;A&#46; Lowe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Bone Jt Surg Am"
                        "fecha" => "2000"
                        "volumen" => "82"
                        "paginaInicial" => "1063"
                        "paginaFinal" => "1070"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Identification and fracture outcomes of undiagnosed low bone mineral density in postmenopausal women&#58; results from the national osteoporosis risk assessment"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46;S&#46; Siris"
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                            2 => "E&#46; Barrett-Connor"
                            3 => "K&#46;G&#46; Faulkner"
                            4 => "L&#46;E&#46; Wehren"
                            5 => "T&#46;A&#46; Abbott"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:2 [
                        "tituloSerie" => "J Am Med Assoc"
                        "fecha" => "2001"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Osteoporosis in the European Union&#58; medical management&#44; epidemiology and economic burden"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Hernlund"
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                            4 => "C&#46; Cooper"
                            5 => "J&#46; Stenmark"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s11657-013-0136-1"
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                        "paginaInicial" => "136"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24113837"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "identificador" => "bib0100"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Burden of epilepsy in Colombia"
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                      ]
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                        "paginaInicial" => "144"
                        "paginaFinal" => "148"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25895443"
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Original Article
Prevalence of osteoporosis in Colombia: Data from the National Health Registry from 2012 to 2018
Prevalencia de osteoporosis en Colombia: datos del registro nacional de salud del 2012 al 2018
Daniel G. Fernández-Ávilaa,b,d,
Corresponding author
, Santiago Bernal-Macíasa,b,d, María J. Parrab,d, Diana N. Rincónc,d, Juan M. Gutiérreza,b,d, Diego Rossellic,d
a Unidad de Reumatología, Departamento de Medicina Interna, Hospital Universitario San Ignacio, Bogotá, Colombia
b Facultad de Medicina, Pontificia Universidad Javeriana, Bogotá, Colombia
c Servicio Reumatología, Hospital Militar Central, Bogotá, Colombia
d Departamento de Epidemiología Clínica y Bioestadística, Facultad de Medicina Pontificia Universidad Javeriana, Bogotá, Colombia
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    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0075">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Osteoporosis &#40;OP&#41; and fragility fractures are a public health problem due to the increase in morbidity and mortality that they generate&#46; Because prevalence of the disease is directly proportional to age&#44; OP is becoming increasingly frequent in a population that tends to live longer&#46;<a class="elsevierStyleCrossRef" href="#bib0005"><span class="elsevierStyleSup">1</span></a> However&#44; OP is not on the agenda of public health priorities in Colombia&#44; where other chronic diseases such as cancer&#44; HIV infection&#44; chronic kidney disease&#44; cardiovascular disease&#44; diabetes mellitus&#44; among others&#44; are the focus of the state budget and the interventions of health decision-makers&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> This paper aims to establish the prevalence of OP in Colombia&#44; describe the basic demographic characteristics of patients with this disease and give visibility to a problem that is silent but with multiple repercussions on our country&#8217;s health system&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0080">Material and method</span><p id="par0010" class="elsevierStylePara elsevierViewall">A cross-sectional study was conducted based on official data from the Colombian Ministry of Health&#46; The official data from the Colombian Ministry of Health come from an information collection and storage tool called the Integral Social Protection Information System &#40;SISPRO&#41;&#44; which has four components&#58; health&#44; pensions&#44; occupational risks&#44; and social promotion&#46; The first component stores and processes the basic and minimum data required by the General System of Social Security in Health for management&#44; regulation&#44; and control processes&#46; This data is entered from the Individual Registry of Health Service Delivery&#46; The information contained in these databases is for public use&#46; The dynamic tables that the Ministry of Health has online were consulted and the data were obtained to conduct this study&#46; Information was obtained for Colombia for the period from 1 January 2012 to 31 December 2018&#44; for which an analysis of the Individual Registry of Health Service Delivery databases was undertaken&#44; using the international codes of diseases &#40;ICD-10&#41; for osteoporosis &#40;M800&#44; M801&#44; M802&#44; M803&#44; M804&#44; M805&#44; M808&#44; M809&#44; M810&#44; M811&#44; M812&#44; M813&#44; M814&#44; M815&#44; M818&#44; M819&#41;&#44; and we analysed variables such as sex&#44; type of insurance and distribution in five-year age groups&#44; according to the official projections of the National Administrative Department of Statistics&#44; based on the projections of the 2005 national census&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a> The data collected were analysed with descriptive statistics&#44; using means and measures of central tendency for quantitative variables and proportions for qualitative variables&#46; Prevalence was adjusted by sex and age group to the 2015 population over 50 years of age&#44; projected for each of the 32 departments during the period analysed&#46; The diagnostic criteria for OP in the SISPRO database are not standardised&#59; they depend on the clinical and diagnostic judgement of each physician when registering a patient with an ICD-10 code related to OP&#46; Patients who were registered with a diagnosis of OP as the &#8220;principal diagnosis&#8221; were included&#46; It is important to highlight that the coverage of the Colombian health system is one of the highest in Latin America &#40;95&#46;1&#37;&#41;&#44;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> which allows for a significant amount of data from the entire population of the country&#46; This project was approved by our institution&#8217;s Central Research Committee&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0085">Results</span><p id="par0015" class="elsevierStylePara elsevierViewall">We identified 249&#44;803 cases &#40;&#8220;persons attended&#8221;&#41; with a principal diagnosis of OP&#44; which allowed us to calculate an unadjusted prevalence of 2440 cases per 100&#44;000 inhabitants over 50 years of age&#44; and to establish that the condition is more frequent in women &#40;92&#37; of cases&#41;&#44; with a female&#58; male ratio of 12&#46;3&#58;1&#46; An analysis of the prevalence of OP by five-year age groups shows an increase in prevalence as the population ages &#40;<a class="elsevierStyleCrossRef" href="#tbl0005">Table 1</a> and <a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; The number of patients according to sex and age group is presented in <a class="elsevierStyleCrossRef" href="#tbl0010">Table 2</a>&#46; It can be observed that the prevalence of OP is higher in women &#40;4210 per 100&#44;000 inhabitants&#41; compared to men &#40;395 per 100&#44;000 inhabitants&#41;&#44; and that prevalence increases as the population ages&#46;</p><elsevierMultimedia ident="tbl0005"></elsevierMultimedia><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="tbl0010"></elsevierMultimedia><p id="par0020" class="elsevierStylePara elsevierViewall">We also analysed the presence of OP with fractures&#44; which corresponded to 18&#37; of the total cases of osteoporosis&#46; Due to the characteristics of the Registry&#44; it was not possible to establish the fracture site&#46; In the analysis by sex&#44; we observed that 22&#37; of men with OP have fractures compared to 18&#37; of women&#46; Given these results&#44; we undertook an analysis of the prevalence of OP with fracture adjusted for sex and age&#44; which showed that the prevalence of OP with fracture is 1&#37; in women and &#46;1&#37; in men&#46;</p><p id="par0025" class="elsevierStylePara elsevierViewall">Regarding the distribution of OP by department&#44; we found that the national population-adjusted prevalence in men ranged between 2&#46;3 and 206&#46;2 per 100&#44;000 inhabitants&#44; while the adjusted prevalence in women was between 12 and 2190 per 100&#44;000 inhabitants &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41;&#46; The areas with the highest adjusted prevalence in both men and women are three departments of the coffee-growing region&#58; Risaralda &#40;6&#46;8 per 100&#44;000 inhabitants&#41;&#44; Antioquia &#40;6&#46;2 per 100&#44;000 inhabitants&#41; and Caldas &#40;5&#46;8 per 100&#44;000 inhabitants&#41;&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0090">Discussion</span><p id="par0030" class="elsevierStylePara elsevierViewall">Colombia is in a process of demographic transition&#44; as are other countries in the region&#44; due to increased longevity of the population&#46; Life expectancy according to the WHO for Colombia is 77 years&#44; and when differentiated by sex&#44; it is 80 years for women and 74 years for men&#46;<a class="elsevierStyleCrossRefs" href="#bib0025"><span class="elsevierStyleSup">5&#44;6</span></a> One of the notable consequences of this demographic phenomenon is an increase in the prevalence of chronic non-communicable diseases&#46; This phenomenon has been documented worldwide in the case of OP&#44; which is a disease considered a public health problem because it affects postmenopausal women and the elderly population&#44; increasing the risk and incidence of fractures&#44; with significant social and economic costs for health systems&#46;<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">7&#44;8</span></a> It is estimated that approximately 200 million people suffer from OP worldwide&#44; with a progressive increase associated with the global ageing of the population&#44; although the prevalence of OP is difficult to establish&#44; given its asymptomatic course until the onset of fractures&#46;<a class="elsevierStyleCrossRefs" href="#bib0035"><span class="elsevierStyleSup">7&#8211;9</span></a></p><p id="par0035" class="elsevierStylePara elsevierViewall">According to the projections of the International Osteoporosis Foundation&#8217;s report presented in 2012&#44; it was evident that the data in Latin America were insufficient&#44; but the estimates indicated that there were 1&#44;423&#44;559 women with OP in Colombia and 8000&#8211;10&#44;000 hip fractures per year&#46;<a class="elsevierStyleCrossRef" href="#bib0010"><span class="elsevierStyleSup">2</span></a> However&#44; the data obtained from the Ministry of Health registry reports only 249&#44;803 people with OP&#44; which is one-fifth of the estimate of the International Osteoporosis Foundation&#46; Other work such as that by Morales-Torres et al&#46; collected data from Latin America&#44; where the range of vertebral OP was 7&#46;6&#37;&#8211;12&#46;1&#37; and of femoral neck OP was 7&#46;9&#37;&#8211;22&#37;&#44;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">8</span></a> which again is higher than that found in our study&#44; where the overall prevalence is 2&#46;4&#37; in those over 50 years of age&#46; A report from Bogota in 1999 reported a prevalence of OP of 32&#37; in a group of patients who underwent bone scans&#44;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">10</span></a> which again contrasts with the findings of the national registry&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">The results of this study show that OP occurs more frequently in women of all age ranges and its prevalence increases in a directly proportional manner&#44; which is in line with that reported in other studies in Latin America &#40;LAVOS&#44; Brazil&#41;<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">11&#44;12</span></a> and in other regions &#40;Spain&#44; China&#44; Canada&#41;&#46;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">13&#8211;15</span></a> However&#44; the lower prevalence than that reported in other studies may be due to under-diagnosis and under-recording in the SISPRO information system&#44; as well as the difference in the methodology of the studies&#44; since the methodology used to measure prevalence in the studies that we took as the reference for this article&#8217;s discussion was taking densitometry measurements of specific population groups using the active search mode&#44; or by analysing hospital records in at-risk populations&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">In terms of the prevalence of OP fractures&#44; these are two to three times more common in women&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">16</span></a> Worldwide&#44; about 8&#46;9 million fractures per year are attributable to OP&#46;<a class="elsevierStyleCrossRef" href="#bib0080"><span class="elsevierStyleSup">16</span></a> However&#44; there is likely to be under-reporting&#44; because some fragility fractures are under-diagnosed and under-treated&#44;<a class="elsevierStyleCrossRefs" href="#bib0085"><span class="elsevierStyleSup">17&#44;18</span></a> leading to the functional impairment of sufferers&#44; decreased quality of life and high mortality rates&#46;<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">11&#44;16</span></a> In 2010&#44; around 3&#46;5 million fractures in Europe were attributed to OP&#44; hip fracture being the most frequent&#46;<a class="elsevierStyleCrossRef" href="#bib0095"><span class="elsevierStyleSup">19</span></a> The LAVOS study&#44; conducted in 5 Latin American countries &#40;Argentina&#44; Brazil&#44; Colombia&#44; Mexico and Puerto Rico&#41; showed a standardised prevalence of vertebral fractures in women over 50 years of age of 11&#46;18&#37; &#40;95&#37; CI 9&#46;23&#8211;13&#46;4&#41;&#44; which increases from 6&#46;9&#37; in women aged 50&#8211;59 years to 27&#46;8&#37; in women over 80 years&#46;<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">12</span></a> This direct relationship between ageing and increased prevalence of fractures is also determined by the findings of our study&#44; as is the higher prevalence of OP among women&#46;</p><p id="par0050" class="elsevierStylePara elsevierViewall">The Colombian health system is based on single-payer public financing and mixed public and private provision&#44; with almost universal coverage &#40;95&#46;1&#37; according to the latest official measurement in June 2019&#41;&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> However&#44; the main limitation of this study is underreporting&#44; due to the characteristics of the Registry&#44; which only records the main diagnoses&#44; not comorbidities&#44; which in the case of OP&#44; as it is often a comorbidity&#44; is not adequately recorded&#46; Neither is it possible to calculate the incidence because there is no criterion to determine the &#8220;main diagnosis&#8221; from one year to another&#46; As there can be variations in recording&#44; it is not possible to calculate the incidence or duration of the disease&#46;<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">20</span></a> Also&#44; due to the nature of the data&#44; it is not possible to establish the course of the disease&#44; the patients&#8217; specific clinical characteristics&#44; fracture sites&#44; or response to treatment&#46;</p><p id="par0055" class="elsevierStylePara elsevierViewall">Our study shows information taken from the Colombian Ministry of Health database&#46; From this information we made demographic and epidemiological analyses of the population and projections for the care of patients with OP in our country&#46; These results alert us to the importance of improving the characteristics of the Registry&#44; and of designing public health policies for a disease which is possibly being under-diagnosed and therefore&#44; with a lower rate of treatment for patients&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0095">Conflict of interests</span><p id="par0060" class="elsevierStylePara elsevierViewall">The authors have no conflict of interests to declare&#46;</p></span></span>"
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        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Introduction</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Osteoporosis is considered a healthcare problem due to the increased risk of fractures and high cost of care&#46; In Colombia&#44; the Ministry of Health introduced SISPRO&#44; a tool to collect nationwide information from the health system&#46; The information collected from SISPRO is available for scientific analysis&#46; This article presents an analysis of the prevalence and characteristics of patients with osteoporosis using data from 2012 to 2018&#46;</p></span> <span id="abst0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Aim</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">To estimate prevalence of osteoporosis between January 2012 to December 2018 and describe the patients&#8217; demographic characteristics&#46;</p></span> <span id="abst0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Methods</span><p id="spar0045" class="elsevierStyleSimplePara elsevierViewall">This is a descriptive epidemiological study using the International Statistical Classification of Diseases and Related Health Problems related to osteoporosis as search terms using the SISPRO database&#46;</p></span> <span id="abst0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Results</span><p id="spar0050" class="elsevierStyleSimplePara elsevierViewall">National records report 249&#44;803 patients over 50 years old diagnosed with osteoporosis&#46; The estimated prevalence is 2440 cases per 100&#44;000 inhabitants over 50 years old &#40;based on a total population of 10&#44;236&#44;132&#41;&#44; being more frequent in women &#40;92&#37; of cases&#41;&#44; with a female&#47;male ratio of 12&#46;3&#58;1&#46;</p></span> <span id="abst0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Conclusion</span><p id="spar0055" class="elsevierStyleSimplePara elsevierViewall">This study shows a lower prevalence than previous estimates or projections&#46; Given these findings we think it is necessary to act to promote health policies for patients with osteoporosis&#46;</p></span>"
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        "resumen" => "<span id="abst0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Introducci&#243;n</span><p id="spar0060" class="elsevierStyleSimplePara elsevierViewall">La osteoporosis es considerada un problema de salud p&#250;blica&#44; ya que&#44; al aumentar el riesgo de fracturas&#44; genera un alto coste para el sistema de salud&#46; En Colombia&#44; el Ministerio de Salud utiliza la herramienta SISPRO para recolectar informaci&#243;n del sistema de salud&#46; La informaci&#243;n almacenada en SISPRO es p&#250;blica y disponible para la investigaci&#243;n&#46; Este art&#237;culo presenta un an&#225;lisis de la prevalencia y caracter&#237;sticas de los pacientes con osteoporosis a partir de los datos del 2012 al 2018&#46;</p></span> <span id="abst0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Objetivos</span><p id="spar0065" class="elsevierStyleSimplePara elsevierViewall">Estimar la prevalencia de osteoporosis entre enero de 2012 a diciembre de 2018 y describir las caracter&#237;sticas demogr&#225;ficas de los pacientes&#46;</p></span> <span id="abst0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">M&#233;todos</span><p id="spar0070" class="elsevierStyleSimplePara elsevierViewall">Estudio descriptivo de corte transversal en el que se tomaron los datos de SISPRO&#44; utilizando como palabras clave los diagn&#243;sticos del manual internacional de enfermedades relacionados con el diagn&#243;stico de osteoporosis&#46;</p></span> <span id="abst0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Resultados</span><p id="spar0075" class="elsevierStyleSimplePara elsevierViewall">Se documentaron 249&#46;803 individuos mayores de 50 a&#241;os con diagn&#243;stico de osteoporosis&#44; estimando una prevalencia de 2&#46;440 casos por 100&#46;000 habitantes mayores de 50 a&#241;os &#40;basado en una poblaci&#243;n total de 10&#46;236&#46;132&#41;&#44; siendo m&#225;s frecuente en mujeres &#40;92&#37;&#41;&#44; con una relaci&#243;n mujer a hombre de 12&#44;3&#58;1&#46;</p></span> <span id="abst0050" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Conclusi&#243;n</span><p id="spar0080" class="elsevierStyleSimplePara elsevierViewall">Este estudio muestra una baja prevalencia respecto a las estimaciones y proyecciones&#46; Dados estos resultados es necesario trabajar en promover pol&#237;ticas en salud para los pacientes con osteoporosis&#46;</p></span>"
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        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Fern&#225;ndez-&#193;vila DG&#44; Bernal-Mac&#237;as S&#44; Parra MJ&#44; Rinc&#243;n DN&#44; Guti&#233;rrez JM&#44; Rosselli D&#46; Prevalencia de osteoporosis en Colombia&#58; datos del registro nacional de salud del 2012 al 2018&#46; Reumatol Clin&#46; 2021&#59;17&#58;570&#8211;574&#46;</p>"
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          "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Geographical distribution of the prevalence of osteoporosis for the period 2012&#8211;2018&#44; adjusting for sex and age group of the Columbian population&#46; Prevalence is calculated with the mean population of the period as the denominator per 100&#44;000 inhabitants&#46; &#40;A&#41; Males&#46; &#40;B&#41; Females&#46;</p>"
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                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">2015&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">2016&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">2017&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Total patients&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">50&#8211;54&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">1&#44;050&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">1&#44;208&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">1&#44;623&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t">1&#44;638&nbsp;\t\t\t\t\t\t\n
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                  \t\t\t\t\ttop\n
                  \t\t\t\t">2&#44;440&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t</td></tr></tbody></table>
                  """
              ]
              "imagenFichero" => array:1 [
                0 => "xTab2753051.png"
              ]
            ]
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Patients seen with a primary diagnosis of osteoporosis by age group between 2012 and 2018&#46;</p>"
        ]
      ]
      3 => array:8 [
        "identificador" => "tbl0010"
        "etiqueta" => "Table 2"
        "tipo" => "MULTIMEDIATABLA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "detalles" => array:1 [
          0 => array:3 [
            "identificador" => "at0020"
            "detalle" => "Table "
            "rol" => "short"
          ]
        ]
        "tabla" => array:2 [
          "leyenda" => "<p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">COL&#58; Colombia&#59; OP&#58; osteoporosis&#46;</p>"
          "tablatextoimagen" => array:1 [
            0 => array:2 [
              "tabla" => array:1 [
                0 => """
                  <table border="0" frame="\n
                  \t\t\t\t\tvoid\n
                  \t\t\t\t" class=""><thead title="thead"><tr title="table-row"><th class="td" title="\n
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                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col">&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " colspan="5" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Males</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " colspan="5" align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Females</th></tr><tr title="table-row"><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Age group&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Males with OP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Prevalence of OP &#40;&#215;100&#44;000 inhab&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Males with fractures and OP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">OP with fractures &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Prevalence of OP with fractures in COL &#40;&#215;100&#44;000 inhab&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Females with OP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Prevalence of OP &#40;&#215;100&#44;000 inhab&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Females with fractures and OP&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">OP with fractures &#40;&#37;&#41;&nbsp;\t\t\t\t\t\t\n
                  \t\t\t\t\t\t</th><th class="td" title="\n
                  \t\t\t\t\ttable-head\n
                  \t\t\t\t  " align="left" valign="\n
                  \t\t\t\t\ttop\n
                  \t\t\t\t" scope="col" style="border-bottom: 2px solid black">Prevalence of OP with fractures in COL &#40;&#215;100&#44;000 inhab&#41;&nbsp;\t\t\t\t\t\t\n
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                          "autores" => array:3 [
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                        "tituloSerie" => "Nat Rev Rheumatol"
                        "fecha" => "2010"
                        "volumen" => "6"
                        "paginaInicial" => "99"
                        "paginaFinal" => "105"
                        "link" => array:1 [
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                    0 => array:2 [
                      "doi" => "10.1016/j.bone.2010.06.015"
                      "Revista" => array:6 [
                        "tituloSerie" => "Bone"
                        "fecha" => "2010"
                        "volumen" => "47"
                        "paginaInicial" => "610"
                        "paginaFinal" => "616"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/20601286"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib0070"
              "etiqueta" => "14"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Osteoporosis in China"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "Y&#46; Wang"
                            1 => "Y&#46; Tao"
                            2 => "M&#46;E&#46; Hyman"
                            3 => "J&#46; Li"
                            4 => "Y&#46; Chen"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00198-009-0925-y"
                      "Revista" => array:6 [
                        "tituloSerie" => "Osteoporos Int"
                        "fecha" => "2009"
                        "volumen" => "20"
                        "paginaInicial" => "1651"
                        "paginaFinal" => "1662"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19415374"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib0075"
              "etiqueta" => "15"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The burden of illness of osteoporosis in Canada"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46;E&#46; Tarride"
                            1 => "R&#46;B&#46; Hopkins"
                            2 => "W&#46;D&#46; Leslie"
                            3 => "S&#46; Morin"
                            4 => "J&#46;D&#46; Adachi"
                            5 => "A&#46; Papaioannou"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:4 [
                        "tituloSerie" => "Osteoporos Int"
                        "fecha" => "2012"
                        "volumen" => "23"
                        "paginaInicial" => "2591"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib0080"
              "etiqueta" => "16"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An estimate of the worldwide prevalence and disability associated with osteoporotic fractures"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "O&#46; Johnell"
                            1 => "J&#46;A&#46; Kanis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00198-006-0172-4"
                      "Revista" => array:6 [
                        "tituloSerie" => "Osteoporos Int"
                        "fecha" => "2006"
                        "volumen" => "17"
                        "paginaInicial" => "1726"
                        "paginaFinal" => "1733"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16983459"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib0085"
              "etiqueta" => "17"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Treatment of osteoporosis&#58; are physicians missing an opportunity&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "K&#46;B&#46; Freedman"
                            1 => "F&#46;S&#46; Kaplan"
                            2 => "W&#46;B&#46; Bikler"
                            3 => "B&#46;L&#46; Strom"
                            4 => "R&#46;A&#46; Lowe"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Bone Jt Surg Am"
                        "fecha" => "2000"
                        "volumen" => "82"
                        "paginaInicial" => "1063"
                        "paginaFinal" => "1070"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib0090"
              "etiqueta" => "18"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Identification and fracture outcomes of undiagnosed low bone mineral density in postmenopausal women&#58; results from the national osteoporosis risk assessment"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46;S&#46; Siris"
                            1 => "P&#46;D&#46; Miller"
                            2 => "E&#46; Barrett-Connor"
                            3 => "K&#46;G&#46; Faulkner"
                            4 => "L&#46;E&#46; Wehren"
                            5 => "T&#46;A&#46; Abbott"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:2 [
                        "tituloSerie" => "J Am Med Assoc"
                        "fecha" => "2001"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib0095"
              "etiqueta" => "19"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Osteoporosis in the European Union&#58; medical management&#44; epidemiology and economic burden"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "E&#46; Hernlund"
                            1 => "A&#46; Svedbom"
                            2 => "M&#46; Iverg&#229;rd"
                            3 => "J&#46; Compston"
                            4 => "C&#46; Cooper"
                            5 => "J&#46; Stenmark"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s11657-013-0136-1"
                      "Revista" => array:6 [
                        "tituloSerie" => "Arch Osteoporos&#46;"
                        "fecha" => "2013"
                        "volumen" => "8"
                        "numero" => "1&#8211;2"
                        "paginaInicial" => "136"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24113837"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib0100"
              "etiqueta" => "20"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Burden of epilepsy in Colombia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46; M&#233;ndez-Ayala"
                            1 => "D&#46; Nari&#241;o"
                            2 => "D&#46; Rosselli"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1159/000381424"
                      "Revista" => array:6 [
                        "tituloSerie" => "Neuroepidemiology"
                        "fecha" => "2015"
                        "volumen" => "44"
                        "paginaInicial" => "144"
                        "paginaFinal" => "148"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25895443"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
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ISSN: 21735743
Original language: English
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