TY - JOUR T1 - Prevalence and pattern of myocardial involvement on cardiac magnetic resonance imaging in Takayasu arteritis and its relationship with disease activity JO - Reumatología Clínica (English Edition) T2 - AU - Chattopadhyay,Arghya AU - Singhal,Manphool AU - Debi,Uma AU - Bhal,Ajay AU - Sharma,Aman AU - Jain,Sanjay SN - 1699258X M3 - 10.1016/j.reuma.2021.11.003 DO - 10.1016/j.reuma.2021.11.003 UR - https://reumatologiaclinica.org/es-prevalence-pattern-myocardial-involvement-on-articulo-S1699258X22000225 AB - BackgroundCardiac involvement in Takayasu arteritis (TA) is the major cause of morbidity and mortality. Cardiovascular magnetic resonance (CMR) is an excellent modality for the assessment of myocardial involvement. Studies have shown myocardial involvement in 25%–27% of patients. ObjectivesTo evaluate the prevalence and pattern of myocardial involvement in TA on CMR. We also evaluated any correlation between CMR changes and disease activity score (ITAS 2010 and ITAS-A) assessed at the time of CMR. MethodsPatients classified as Takayasu arteritis according to Sharma et al. criteria were enrolled in the study. Demographic, clinical, and laboratory data were documented in the predesigned proforma. CMR was performed on a dedicated cardiac 3Tesla MR machine. Disease activity was recorded by ITAS2010 and ITAS-A. ResultsA total of 37 TA patients were included. Mean (±SD) age was 29±11 years. Female to male ratio was 3:1. Five patients (14%) had myocardial involvement on CMR. Two (2/5) had myocarditis and three (3/5) patients had features of ischaemic myocardial fibrosis. ConclusionThe myocardium is affected in TA, however the prevalence of subclinical myocardial involvement in our study was less (8% vs. 25%–27%) compared to the previous studies. Myocardial involvement trends towards early age of onset, less disease duration, lack of classical risk factors, and more with disease activity. ER -