TY - JOUR T1 - Dermatomyositis and Myasthenia Gravis: An Uncommon Association With Therapeutic Implications JO - Reumatología Clínica (English Edition) T2 - AU - Sangüesa Gómez,Clara AU - Flores Robles,Bryan Josué AU - Méndez Perles,Clara AU - Barbadillo,Carmen AU - Godoy,Hildegarda AU - Andréu,José Luis SN - 21735743 M3 - 10.1016/j.reumae.2014.12.008 DO - 10.1016/j.reumae.2014.12.008 UR - https://reumatologiaclinica.org/en-dermatomyositis-myasthenia-gravis-an-uncommon-articulo-S2173574314001828 AB - The association of dermatomyositis with myasthenia gravis (MG) is uncommon, having been reported so far in only 26 cases. We report the case of a 69 year-old man diagnosed with MG two years ago and currently treated with piridostigmyne. The patient developed acute proximal weakness, shoulder pain and elevated creatine-kinase (CK). He also developed generalized facial erythema and Gottron's papules. Laboratory tests showed positive antinuclear and anti-Mi2 antibodies. Further analysis confirmed CK levels above 1000U/l. The clinical management of the patient and the therapeutic implications derived from the coexistence of both entities are discussed. ER -