TY - JOUR T1 - Two-year Incidence of Psoriasis, Uveitis and Inflammatory Bowel Disease in Patients With Spondyloarthritis: A Study in the AQUILES Cohort JO - Reumatología Clínica (English Edition) T2 - AU - García-Vicuña,Rosario AU - Zarco,Pedro AU - González,Carlos M. AU - Vanaclocha,Francisco AU - Marín-Jiménez,Ignacio AU - Cea-Calvo,Luis SN - 21735743 M3 - 10.1016/j.reumae.2015.03.011 DO - 10.1016/j.reumae.2015.03.011 UR - https://reumatologiaclinica.org/en-two-year-incidence-psoriasis-uveitis-inflammatory-articulo-S2173574315000532 AB - ObjectivesTo describe the 2-year incidence of new extra-articular manifestations (uveitis, psoriasis, inflammatory bowel disease) in a cohort of patients with spondyloarthritis included in the AQUILES study. PatientsOver a period of 2 years, 513 patients with spondyloarthritis (62.5% males, mean age 48 years) diagnosed with ankylosing spondylitis (AS) (55.6%), psoriatic arthritis (25.3%), undifferentiated spondyloarthritis (16.2%), enteropathic arthritis (2.5%), and other diseases (0.4%) were followed. New diagnoses were based on reports of the corresponding specialists (ophthalmologists, dermatologists, gastroenterologists). ResultsDuring the 2-year follow-up, 22 new diagnoses of the extra-articular manifestations were established, with a cumulative incidence of 4.3% (95% confidence interval 2.4–6.1) and an incidence rate of 17 cases per 10,000 patient-year. Uveitis was the most frequent diagnosis (cumulative incidence 3.1%), predominantly in patients with AS. In the multivariate analysis, the diagnosis of AS was the only predictive variable associated to the development of new extra-articular disease. ConclusionsIn patients with spondyloarthritis, the 2-year global incidence of uveitis, psoriasis and inflammatory bowel disease (IMID) was 4.3%, particularly due to new diagnoses of uveitis in patients with AS. ER -