TY - JOUR T1 - Use of Immunomodulatory Drugs at a Uveitis Clinic JO - Reumatología Clínica (English Edition) T2 - AU - Millán-Longo,Claudia AU - Peiteado,Diana AU - Schlincker,Armelle AU - Hidalgo,Ventura AU - Pieren,Amara AU - Balsa,Alejandro AU - de Miguel,Eugenio SN - 21735743 M3 - 10.1016/j.reumae.2017.09.004 DO - 10.1016/j.reumae.2017.09.004 UR - https://reumatologiaclinica.org/en-use-immunomodulatory-drugs-at-uveitis-articulo-S2173574318301102 AB - ObjectiveThe treatment of noninfectious uveitis includes steroids and immunomodulatory drugs, the use of which has increased in the last few years, and the options have been enriched with the development of new treatments. However, clear therapeutic guidelines and protocols have not been developed. The purpose is to analyse the response to the drugs used and the characteristics of the patients treated at a multidisciplinary uveitis clinic. Material and methodsObservational and retrospective study of the patients attended to from January 2012 to December 2015. Infectious, posttraumatic and postoperative uveitis, as well as masquerade syndrome, were excluded. ResultsTwo hundred six patients were included. Overall, 58.80% had uveitis without association of systemic disease, mostly idiopathic uveitis, and 35.65% had uveitis with systemic involvement, mainly related to spondyloarthritis. Uveitis without systemic association and anterior uveitis achieved disease control with local treatment more frequently than others (P=.002 and P<.001, respectively). In all, 49.76% of the patients required systemic treatment. Among those treated with immunomodulators, 53.26% needed a second drug and 31.52% needed a third drug. Women required immunomodulators more often than men (P=.042). Methotrexate was the most widely used immunomodulator. Posterior uveitis responded less favourably to the second immunomodulator than anterior uveitis (P=.006). ConclusionsAlmost half of the patients needed an immunomodulatory drug and some of them required successive drug changes. Intermediate uveitis was the most treatment-refractory uveitis. ER -