TY - JOUR T1 - Esophageal symptoms and their lack of association with high-resolution manometry in systemic sclerosis patients JO - Reumatología Clínica (English Edition) T2 - AU - Arana-Guajardo,Ana Cecilia AU - Barrera-Torres,Gustavo AU - Villarreal-Alarcón,Miguel Ángel AU - Vega-Morales,David AU - Esquivel-Valerio,Jorge Antonio SN - 21735743 M3 - 10.1016/j.reumae.2017.09.005 DO - 10.1016/j.reumae.2017.09.005 UR - https://reumatologiaclinica.org/en-esophageal-symptoms-their-lack-association-articulo-S2173574319300425 AB - BackgroundThe esophageal involvement in systemic sclerosis (SSc) causes impact in the morbidity and mortality. High resolution manometry assesses esophageal involvement. Our aim was to categorize esophageal motor disorder in patients with SSc by HRM. MethodsWe carried out an observational, descriptive and cross-sectional study. All patients underwent HRM as well as semi-structured interviews to assess frequency and severity of upper GI symptoms. Patients also completed the gastroesophageal reflux questionnaire (Carlsson–Dent). ResultsWe included 19 patients with SSc, 1 with morphea, and 1 with scleroderma sine scleroderma. Dysphagia and heartburn were the most frequent symptoms (61% each). We found an abnormal HRM in 15 (71.4%) patients. We found no statistically significant association between clinical or demographic variables and an abnormal HRM, or between any upper GI symptom and HRM findings. ConclusionWe observed a high prevalence of esophageal symptoms and of HRM abnormalities. However, there was no clear association between symptomatology and HRM findings. HRM does not seem to accurately predict upper GI symptomatology. ER -