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Case Report
DOI: 10.1016/j.reumae.2017.08.012
Available online 13 September 2019
Gonococcal arthritis and C2 deficiency
Artritis gonocócica y déficit de C2
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Diego Benavent Núñeza,
Corresponding author
d_benavent@hotmail.com

Corresponding author.
, Carolina Tornero Marína, Gema Bonilla Hernána, Adela García Pereab, Alejandro Balsa Criadoa, Alicia Rico Nietob
a Servicio de Reumatología, Hospital Universitario La Paz, Madrid, Spain
b Servicio de Microbiología, Hospital Universitario La Paz, Madrid, Spain
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Received 17 March 2017. Accepted 10 August 2017
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Abstract

Disseminated gonococcal infection is a rare presentation of the sexually transmitted pathogen, Neisseria gonorrhoeae. Here, we report the case of a 64-year-old woman with disseminated gonococcal infection, which started with symptoms of oligoarthritis and malaise. Neisseria gonorrhoeae was identified in the carpal synovial fluid. The follow-up study revealed an absence of total hemolytic complement and complement C2 was not detected. Being relatively common, C2 deficiency has been associated with disseminated gonococcal infection in a few cases. We present a new case and discuss those previously published.

Keywords:
Disseminated gonococcal infection
Gonococcus
Complement
Sternoclavicular arthritis
Resumen

La enfermedad gonocócica diseminada es una manifestación infrecuente de la afectación por Neisseria gonorrhoeae, que presenta una clínica variada y no bien definida, siendo la afectación articular un hallazgo característico. Presentamos el caso de una mujer de 64 años con enfermedad gonocócica diseminada de inicio agudo, que comenzó con deterioro generalizado y oligoartritis. Se realizó artrocentesis de carpo, obteniéndose un líquido sinovial de aspecto purulento, cuyo estudio microbiológico identificó Neisseira gonorrhoeae. En el estudio se objetivó un complemento hemolítico total (CH50) de cero, no detectándose la fracción C2 del complemento. Son muy pocos los casos descritos en la literatura de enfermedad gonocócica diseminada asociada a déficit de C2. Presentamos un nuevo caso y revisamos los previamente publicados.

Palabras clave:
Enfermedad gonocócica diseminada
Gonococo
Complemento
Artritis esternoclavicular

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