array:23 [
  "pii" => "S2173574309700814"
  "issn" => "21735743"
  "doi" => "10.1016/S2173-5743(09)70081-4"
  "estado" => "S300"
  "fechaPublicacion" => "2009-01-01"
  "aid" => "70081"
  "copyright" => "Sociedad Española de Reumatología and Colegio Mexicano de Reumatología"
  "copyrightAnyo" => "2009"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Reumatol Clin. 2009;5:13-7"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 2096
    "formatos" => array:3 [
      "EPUB" => 44
      "HTML" => 1531
      "PDF" => 521
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S2173574309700826"
    "issn" => "21735743"
    "doi" => "10.1016/S2173-5743(09)70082-6"
    "estado" => "S300"
    "fechaPublicacion" => "2009-01-01"
    "aid" => "70082"
    "copyright" => "Sociedad Española de Reumatología and Colegio Mexicano de Reumatología"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Reumatol Clin. 2009;5:18-22"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 3021
      "formatos" => array:3 [
        "EPUB" => 45
        "HTML" => 1777
        "PDF" => 1199
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Polyarticular Septic Arthritis: Analysis of 19 Cases"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "18"
          "paginaFinal" => "22"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Artritis séptica politópica: análisis de 19 casos"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Lourdes Mateo Soria, Alejandro Olivé Marqués, Elisabet García Casares, Emma García Melchor, Susana Holgado Pérez, Xavier Tena Marsà"
          "autores" => array:6 [
            0 => array:2 [
              "nombre" => "Lourdes"
              "apellidos" => "Mateo Soria"
            ]
            1 => array:2 [
              "nombre" => "Alejandro"
              "apellidos" => "Olivé Marqués"
            ]
            2 => array:2 [
              "nombre" => "Elisabet"
              "apellidos" => "García Casares"
            ]
            3 => array:2 [
              "nombre" => "Emma"
              "apellidos" => "García Melchor"
            ]
            4 => array:2 [
              "nombre" => "Susana"
              "apellidos" => "Holgado Pérez"
            ]
            5 => array:2 [
              "nombre" => "Xavier"
              "apellidos" => "Tena Marsà"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574309700826?idApp=UINPBA00004M"
    "url" => "/21735743/0000000500000001/v1_201305061551/S2173574309700826/v1_201305061551/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S2173574309700802"
    "issn" => "21735743"
    "doi" => "10.1016/S2173-5743(09)70080-2"
    "estado" => "S300"
    "fechaPublicacion" => "2009-01-01"
    "aid" => "70080"
    "copyright" => "Sociedad Española de Reumatología and Colegio Mexicano de Reumatología"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Reumatol Clin. 2009;5:3-12"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2671
      "formatos" => array:3 [
        "EPUB" => 44
        "HTML" => 1689
        "PDF" => 938
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Appropriate Use of Non-steroidal Anti-inflammatory Drugs in Rheumatology: Guidelines From the Spanish Society of Rheumatology and the Mexican College of Rheumatology"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "3"
          "paginaFinal" => "12"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Uso apropiado de los antiinflamatorios no esteroideos en reumatología: documento de consenso de la Sociedad Española de Reumatología y el Colegio Mexicano de Reumatología"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Gerardo Bori Segura, Blanca Hernández Cruz, Milena Gobbo, Ángel Lanas Arbeloa, Mario Salazar Páramo, Leobardo Terán Estrada, José Federico Díaz González, Rolando Espinosa Morales, Federico Galván Villegas, Luis Alberto García Rodríguez, José María Álvaro-Gracia Álvaro, Hilario Ávila Armengol, Loreto Carmona, Javier Rivera Redondo, Lucio Ventura Ríos"
          "autores" => array:15 [
            0 => array:2 [
              "nombre" => "Gerardo"
              "apellidos" => "Bori Segura"
            ]
            1 => array:2 [
              "nombre" => "Blanca"
              "apellidos" => "Hernández Cruz"
            ]
            2 => array:2 [
              "nombre" => "Milena"
              "apellidos" => "Gobbo"
            ]
            3 => array:2 [
              "nombre" => "Ángel"
              "apellidos" => "Lanas Arbeloa"
            ]
            4 => array:2 [
              "nombre" => "Mario"
              "apellidos" => "Salazar Páramo"
            ]
            5 => array:2 [
              "nombre" => "Leobardo"
              "apellidos" => "Terán Estrada"
            ]
            6 => array:2 [
              "nombre" => "José Federico"
              "apellidos" => "Díaz González"
            ]
            7 => array:2 [
              "nombre" => "Rolando"
              "apellidos" => "Espinosa Morales"
            ]
            8 => array:2 [
              "nombre" => "Federico"
              "apellidos" => "Galván Villegas"
            ]
            9 => array:2 [
              "nombre" => "Luis Alberto"
              "apellidos" => "García Rodríguez"
            ]
            10 => array:2 [
              "nombre" => "José María"
              "apellidos" => "Álvaro-Gracia Álvaro"
            ]
            11 => array:2 [
              "nombre" => "Hilario"
              "apellidos" => "Ávila Armengol"
            ]
            12 => array:2 [
              "nombre" => "Loreto"
              "apellidos" => "Carmona"
            ]
            13 => array:2 [
              "nombre" => "Javier"
              "apellidos" => "Rivera Redondo"
            ]
            14 => array:2 [
              "nombre" => "Lucio"
              "apellidos" => "Ventura Ríos"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574309700802?idApp=UINPBA00004M"
    "url" => "/21735743/0000000500000001/v1_201305061551/S2173574309700802/v1_201305061551/en/main.assets"
  ]
  "en" => array:14 [
    "idiomaDefecto" => true
    "titulo" => "Osteopenia in Primary Health Care Patients: Do We Need to Be More Rigorous?"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "13"
        "paginaFinal" => "17"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Antoni Serra Torres, Salvador Sitjar Martínez de Sas, Josep Miquel Sotoca Momblona, Laia Alemany Vilches, Bibiana Contreras Raris, Jordi Hoyo Sánchez"
        "autores" => array:6 [
          0 => array:3 [
            "nombre" => "Antoni"
            "apellidos" => "Serra Torres"
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          1 => array:4 [
            "nombre" => "Salvador Sitjar"
            "apellidos" => "Mart&#237;nez de Sas"
            "email" => array:1 [
              0 => "ssitjar&#64;clinic&#46;ub&#46;es"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Josep Miquel"
            "apellidos" => "Sotoca Momblona"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Laia"
            "apellidos" => "Alemany Vilches"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "Bibiana"
            "apellidos" => "Contreras Raris"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
          5 => array:3 [
            "nombre" => "Jordi"
            "apellidos" => "Hoyo S&#225;nchez"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:2 [
          0 => array:3 [
            "entidad" => "CAP Les Corts&#44; Barcelona&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">a</span>"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "CS Marines-UBS Can Picafort&#44; Mallorca&#44; Illes Balears&#44; Spain"
            "etiqueta" => "<span class="elsevierStyleSup">b</span>"
            "identificador" => "aff0010"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Osteopenia en atenci&#243;n primaria&#58; &#191;debemos ser m&#225;s rigurosos&#63;"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2008-03-07"
    "fechaAceptado" => "2008-06-02"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec111970"
          "palabras" => array:5 [
            0 => "Osteoporosis"
            1 => "Preventive measures"
            2 => "Calcium compounds"
            3 => "Therapeutic use"
            4 => "Patient compliance"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec111971"
          "palabras" => array:5 [
            0 => "Osteoporosis"
            1 => "Medidas preventivas"
            2 => "Calcio"
            3 => "Uso terap&#233;utico"
            4 => "Cumplimiento"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Aim</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To describe the treatment prescribed to osteopenic women seen at an urban primary health care centre and the treatment compliance of those patients with a prescription of calcium and&#47;or vitamin D&#46;</p> <span class="elsevierStyleSectionTitle">Materials and method</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Cross-sectional study&#44; osteopenic women diagnosed by bone densitometry between February 2005 and January 2006 &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>121&#41;&#46; Clinical history review&#58; demographic information&#59; previous clinical history of bone fracture&#44; type of fracture&#59; parental history of fractures&#59; tobacco use&#59; osteoporosisrelated medication or disease&#59; dietary and sun exposure assessment&#59; calcium&#44; vitamin D and raloxifene&#47; biphosphonates prescription&#59; mean daily dose of calcium and vitamin D supplements collected at the pharmacy by patients&#46; Analysis of treatment prescription and compliance according to the information collected was performed&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Mean age&#44; 61&#46;9 &#40;9&#46;1&#41; years&#59; 90&#46;7&#37; post-menopausic&#46; The dietary assessment was performed in 30&#46;5&#37; of the women included in the study&#46; The drug prescription was as follows&#58; calcium 74&#46;6&#37;&#44; vitamin D 68&#46;6&#37;&#44; and raloxifene&#47;biphosphonates 16&#46;1&#37;&#46; All drug prescriptions were associated with lower T-score values&#46; The patient&#39;s compliance of calcium supplements has been calculated as mean of 423&#46;8 &#40;321&#46;7&#41; mg&#47;day&#44; and 343&#46;1 &#40;225&#46;9&#41; IU of vitamin D&#59; with no association with any of the studied variables&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">We identified greater drug prescription in those patients with a lower T-score&#46; The clinical history of previous fracture did not show association with drug prescription nor a better compliance&#46; There was a lack of information about relevant issues in the clinical history of the osteopenic women included in the study&#46; The patient&#39;s compliance of calcium and vitamin-D supplements is very variable&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Describir el tratamiento prescrito a mujeres osteop&#233;nicas atendidas en un centro de atenci&#243;n primaria urbano y el cumplimiento de las pacientes que reciben prescripci&#243;n de calcio o vitamina D&#46;</p> <span class="elsevierStyleSectionTitle">Material y m&#233;todos</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Estudio transversal en mujeres con osteopenia diagnosticada por densitometr&#237;a &#243;sea &#40;DMO&#41; entre febrero de 2005 y enero de 2006 &#40;n<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>118&#41;&#46; Comprobaci&#243;n en la historia cl&#237;nica de&#58; informaci&#243;n demogr&#225;fica&#59; antecedentes de fractura&#44; tipo&#59; antecedentes familiares de fractura&#59; h&#225;bito tab&#225;quico&#59; toma de f&#225;rmacos o antecedente de enfermedad cr&#243;nica relacionados con disminuci&#243;n de DMO&#59; valoraci&#243;n&#47; consejo diet&#233;tico&#44; valoraci&#243;n de exposici&#243;n solar&#59; prescripci&#243;n de calcio&#44; vitamina D y raloxifeno&#47; bisfosfonatos&#59; dosis diaria media de calcio y vitamina D recogida por las pacientes de la farmacia&#46; An&#225;lisis de la prescripci&#243;n de f&#225;rmacos y del cumplimiento en funci&#243;n de las variables recogidas&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Media de edad&#44; 61&#44;9<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>9&#44;1 a&#241;os&#59; el 90&#44;7&#37; posmenop&#225;usicas&#46; La valoraci&#243;n&#47;consejo diet&#233;tico se encontr&#243; en el 30&#44;5&#37;&#46; La prescripci&#243;n de f&#225;rmacos fue&#58; calcio&#44; 74&#44;6&#37;&#59; vitamina D&#44; 68&#44;6&#37;&#44; y raloxifeno&#47; bisfosfonato&#44; 16&#44;1&#37;&#46; La prescripci&#243;n de todos los f&#225;rmacos se asoci&#243; a valores m&#225;s bajos de T-score&#46; El cumplimiento medio de las mujeres se estim&#243; en 423&#44;8<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>321&#44;7 mg Ca&#47;d&#237;a&#44; y 343&#44;1<span class="elsevierStyleHsp" style=""></span>&#177;<span class="elsevierStyleHsp" style=""></span>225&#44;9 UI de vitamina D&#44; sin relaci&#243;n significativa con ninguna de las variables estudiadas&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">Se identifica una mayor prescripci&#243;n de los tratamientos farmacol&#243;gicos en pacientes con valores de T-score menores&#46; El antecedente personal de fractura no se asocia a la prescripci&#243;n de f&#225;rmacos ni al mejor cumplimiento por las pacientes&#46; En la historia cl&#237;nica de las mujeres osteop&#233;nicas hay una falta de registro de aspectos relevantes&#46; El cumplimiento de los suplementos de calcio y vitamina D es muy variable&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:17 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "World Health Organisation&#46; Assessment of fractures risk in screening for osteoporosis&#46; WHO technical report series 843&#46; Geneva&#58; WHO&#59; 1994&#46;"
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Study of bone mineral density in lumbar spine and femoral neck in a spanish population"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "M&#46; D&#237;az Curiel"
                            1 => "J&#46;L&#46; Carrasco de la Pe&#241;a"
                            2 => "J&#46; Honorato P&#233;rez"
                            3 => "R&#46; P&#233;rez Cano"
                            4 => "A&#46; Rapado"
                            5 => "I&#46; Ru&#237;z Mart&#237;nez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Osteoporos Int"
                        "fecha" => "1997"
                        "volumen" => "7"
                        "paginaInicial" => "59"
                        "paginaFinal" => "64"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9102065"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalencia de osteoporosis determinada por densitometr&#237;a en la poblaci&#243;n femenina espa&#241;ola"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; D&#237;az Curiel"
                            1 => "J&#46;J&#46; Garc&#237;a"
                            2 => "J&#46;L&#46; Carrasco"
                            3 => "J&#46; Honorato"
                            4 => "R&#46; P&#233;rez Cano"
                            5 => "A&#46; Rapado"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "2001"
                        "volumen" => "116"
                        "paginaInicial" => "86"
                        "paginaFinal" => "88"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prevalencia de osteopenia y osteoporosis en mujeres posmenop&#225;usicas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "J&#46; Reyes-Balaguer"
                            1 => "J&#46; Moreno-Olmos"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Aten Primaria"
                        "fecha" => "2005"
                        "volumen" => "35"
                        "paginaInicial" => "342"
                        "paginaFinal" => "347"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15871793"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The effectiveness of bone density measurement and associated treatments for prevention of fractures&#46; An international collaborative review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "D&#46; Hailey"
                            1 => "L&#46; Sampietro-Colom"
                            2 => "D&#46; Marshall"
                            3 => "R&#46; Rico"
                            4 => "A&#46; Granados"
                            5 => "J&#46; Asua"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Int J Technol Assess Health Care"
                        "fecha" => "1998"
                        "volumen" => "14"
                        "paginaInicial" => "237"
                        "paginaFinal" => "254"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9611900"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S187399460700075X"
                          "estado" => "S300"
                          "issn" => "18739946"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Actividades preventivas en el climaterio"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "A&#46; L&#243;pez Garc&#237;a-Franco"
                            1 => "P&#46; Alonso-Coello"
                            2 => "E&#46; Bail&#243;n Bu&#241;oz"
                            3 => "J&#46; Landa-Go&#241;i"
                            4 => "M&#46; Fuentes- Pujol"
                            5 => "J&#46; Ojuel-Solsona"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Aten Primaria"
                        "fecha" => "2005"
                        "volumen" => "36"
                        "numero" => "Suppl 2"
                        "paginaInicial" => "102"
                        "paginaFinal" => "130"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Interim report and recommendations of the World Health Organization Task-Force for osteoporosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "H&#46;K&#46; Genant"
                            1 => "C&#46; Cooper"
                            2 => "G&#46; Poor"
                            3 => "I&#46; Reid"
                            4 => "G&#46; Ehrlich"
                            5 => "D&#46; Kanis"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Osteoporos Int"
                        "fecha" => "1999"
                        "volumen" => "10"
                        "paginaInicial" => "259"
                        "paginaFinal" => "264"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10692972"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "WHO&#46; Scientific group on the assessment of osteoporosis at primary health care level&#46; Summary Meeting Report&#44; Brussels&#44; Belgium&#44; May 5-7&#44; 2004&#46; World Health Organisation&#44; 2007&#46; Available from&#58; <a class="elsevierStyleInterRef" href="http://www.who.int/entity/chp/topics/Osteoporosis.pdf">www&#46;who&#46;int&#47;entity&#47;chp&#47;topics&#47;Osteoporosis&#46;pdf</a>&#46;"
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Closing the osteoporosis management gap in primary care&#58; A secondary prevention of fracture programme"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "E&#46; Brankin"
                            1 => "C&#46; Mitchell"
                            2 => "R&#46; Munro"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1185/030079905X38150"
                      "Revista" => array:7 [
                        "tituloSerie" => "Curr Med Res Opin"
                        "fecha" => "2005"
                        "volumen" => "21"
                        "paginaInicial" => "475"
                        "paginaFinal" => "482"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15899094"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S1873994607000761"
                          "estado" => "S300"
                          "issn" => "18739946"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Risk assessment&#46; Physician&#39;s Guide for the prevention and treatment of osteoporosis&#46; Washington&#58; National Osteoporosis Foundation&#59; 2003&#46;"
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Preventing osteoporosis-related fractures&#58; an overview"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46; Gass"
                            1 => "B&#46; Dawson-Hugues"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.amjmed.2006.09.011"
                      "Revista" => array:7 [
                        "tituloSerie" => "Am J Med"
                        "fecha" => "2006"
                        "volumen" => "119"
                        "numero" => "Suppl 1"
                        "paginaInicial" => "S3"
                        "paginaFinal" => "S11"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17113398"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Investigadores del proyecto ECOSAP&#46; Factores de riesgo de fractura osteopor&#243;tica en una serie de 5&#46; 195 mujeres mayores de 65 a&#241;os"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46; Gonz&#225;lez-Mac&#237;as"
                            1 => "F&#46; Mar&#237;n"
                            2 => "J&#46; Vila"
                            3 => "A&#46; D&#237;ez-P&#233;rez"
                            4 => "M&#46; Abizanda"
                            5 => "R&#46; &#193;lvarez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "2004"
                        "volumen" => "123"
                        "paginaInicial" => "85"
                        "paginaFinal" => "89"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dietary calcium intake among women attending primary care clinics in Wisconsin"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46; Schrager"
                            1 => "M&#46; Girard"
                            2 => "M&#46; Mundt"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Wisc Med J"
                        "fecha" => "2006"
                        "volumen" => "104"
                        "paginaInicial" => "47"
                        "paginaFinal" => "50"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Shea B&#44; Wells G&#44; Cranney A&#44; Zytaruk N&#44; Robinson V&#44; Griffith L&#44; et al&#46; The Osteoporosis Methodology Group&#44; and the Osteoporosis Research Advisory Group&#46; Suplementos de calcio para la p&#233;rdida &#243;sea en mujeres postmenop&#225;usicas &#91;Cochrane review translated&#93;&#46; In&#58; La Biblioteca Cochrane Plus&#44; 2006 N&#250;mero 1&#46;"
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "Avenell A&#44; Gillespie WJ&#44; Gillespie LD&#44; O&#8217;Connell DL&#46; Vitamina D y an&#225;logos para la prevenci&#243;n de fracturas asociadas con la osteoporosis senil y postmenop&#225;usica &#91;Cochrane review translated&#93;&#46; In&#58; La Biblioteca Cochrane Plus&#44; 2006 N&#250;mero 1&#46;"
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "&#91;Hypovitaminosis D associated to low sun exposure in the population over 64 years old&#93;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "M&#46; Vaqueiro"
                            1 => "M&#46; Bar&#233;"
                            2 => "E&#46; Anton"
                            3 => "E&#46; Andreu"
                            4 => "A&#46; Moya"
                            5 => "R&#46; Sampere"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Med Clin &#40;Barc&#41;"
                        "fecha" => "2007"
                        "volumen" => "129"
                        "paginaInicial" => "287"
                        "paginaFinal" => "291"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Amelioration of osteoporosis and hypovitaminosis D by sunlight exposure in hospitalized&#44; elderly women with Alzheimer&#39;s disease&#58; a randomized controlled trial"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "Y&#46; Sato"
                            1 => "J&#46; Iwamoto"
                            2 => "T&#46; Kanoko"
                            3 => "K&#46; Satoh"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1359/JBMR.050402"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Bone Miner Res"
                        "fecha" => "2005"
                        "volumen" => "20"
                        "paginaInicial" => "1327"
                        "paginaFinal" => "1333"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16007329"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735743/0000000500000001/v1_201305061551/S2173574309700814/v1_201305061551/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "17338"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Original Article"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735743/0000000500000001/v1_201305061551/S2173574309700814/v1_201305061551/en/main.pdf?idApp=UINPBA00004M&text.app=https://reumatologiaclinica.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574309700814?idApp=UINPBA00004M"
]
Share
Journal Information
Vol. 5. Issue 1.
Pages 13-17 (January - February 2009)
Share
Share
Download PDF
More article options
Vol. 5. Issue 1.
Pages 13-17 (January - February 2009)
Full text access
Osteopenia in Primary Health Care Patients: Do We Need to Be More Rigorous?
Osteopenia en atención primaria: ¿debemos ser más rigurosos?
Visits
5286
Antoni Serra Torresa,b, Salvador Sitjar Martínez de Sasa,
Corresponding author
ssitjar@clinic.ub.es

Corresponding author.
, Josep Miquel Sotoca Momblonaa, Laia Alemany Vilchesa, Bibiana Contreras Rarisa, Jordi Hoyo Sáncheza
a CAP Les Corts, Barcelona, Spain
b CS Marines-UBS Can Picafort, Mallorca, Illes Balears, Spain
This item has received
Article information
Abstract
Aim

To describe the treatment prescribed to osteopenic women seen at an urban primary health care centre and the treatment compliance of those patients with a prescription of calcium and/or vitamin D.

Materials and method

Cross-sectional study, osteopenic women diagnosed by bone densitometry between February 2005 and January 2006 (n=121). Clinical history review: demographic information; previous clinical history of bone fracture, type of fracture; parental history of fractures; tobacco use; osteoporosisrelated medication or disease; dietary and sun exposure assessment; calcium, vitamin D and raloxifene/ biphosphonates prescription; mean daily dose of calcium and vitamin D supplements collected at the pharmacy by patients. Analysis of treatment prescription and compliance according to the information collected was performed.

Results

Mean age, 61.9 (9.1) years; 90.7% post-menopausic. The dietary assessment was performed in 30.5% of the women included in the study. The drug prescription was as follows: calcium 74.6%, vitamin D 68.6%, and raloxifene/biphosphonates 16.1%. All drug prescriptions were associated with lower T-score values. The patient's compliance of calcium supplements has been calculated as mean of 423.8 (321.7) mg/day, and 343.1 (225.9) IU of vitamin D; with no association with any of the studied variables.

Conclusions

We identified greater drug prescription in those patients with a lower T-score. The clinical history of previous fracture did not show association with drug prescription nor a better compliance. There was a lack of information about relevant issues in the clinical history of the osteopenic women included in the study. The patient's compliance of calcium and vitamin-D supplements is very variable.

Keywords:
Osteoporosis
Preventive measures
Calcium compounds
Therapeutic use
Patient compliance
Resumen
Objetivo

Describir el tratamiento prescrito a mujeres osteopénicas atendidas en un centro de atención primaria urbano y el cumplimiento de las pacientes que reciben prescripción de calcio o vitamina D.

Material y métodos

Estudio transversal en mujeres con osteopenia diagnosticada por densitometría ósea (DMO) entre febrero de 2005 y enero de 2006 (n=118). Comprobación en la historia clínica de: información demográfica; antecedentes de fractura, tipo; antecedentes familiares de fractura; hábito tabáquico; toma de fármacos o antecedente de enfermedad crónica relacionados con disminución de DMO; valoración/ consejo dietético, valoración de exposición solar; prescripción de calcio, vitamina D y raloxifeno/ bisfosfonatos; dosis diaria media de calcio y vitamina D recogida por las pacientes de la farmacia. Análisis de la prescripción de fármacos y del cumplimiento en función de las variables recogidas.

Resultados

Media de edad, 61,9±9,1 años; el 90,7% posmenopáusicas. La valoración/consejo dietético se encontró en el 30,5%. La prescripción de fármacos fue: calcio, 74,6%; vitamina D, 68,6%, y raloxifeno/ bisfosfonato, 16,1%. La prescripción de todos los fármacos se asoció a valores más bajos de T-score. El cumplimiento medio de las mujeres se estimó en 423,8±321,7 mg Ca/día, y 343,1±225,9 UI de vitamina D, sin relación significativa con ninguna de las variables estudiadas.

Conclusiones

Se identifica una mayor prescripción de los tratamientos farmacológicos en pacientes con valores de T-score menores. El antecedente personal de fractura no se asocia a la prescripción de fármacos ni al mejor cumplimiento por las pacientes. En la historia clínica de las mujeres osteopénicas hay una falta de registro de aspectos relevantes. El cumplimiento de los suplementos de calcio y vitamina D es muy variable.

Palabras clave:
Osteoporosis
Medidas preventivas
Calcio
Uso terapéutico
Cumplimiento
Full text is only aviable in PDF
References
[1.]
World Health Organisation. Assessment of fractures risk in screening for osteoporosis. WHO technical report series 843. Geneva: WHO; 1994.
[2.]
M. Díaz Curiel, J.L. Carrasco de la Peña, J. Honorato Pérez, R. Pérez Cano, A. Rapado, I. Ruíz Martínez.
Study of bone mineral density in lumbar spine and femoral neck in a spanish population.
Osteoporos Int, 7 (1997), pp. 59-64
[3.]
M. Díaz Curiel, J.J. García, J.L. Carrasco, J. Honorato, R. Pérez Cano, A. Rapado, et al.
Prevalencia de osteoporosis determinada por densitometría en la población femenina española.
Med Clin (Barc), 116 (2001), pp. 86-88
[4.]
J. Reyes-Balaguer, J. Moreno-Olmos.
Prevalencia de osteopenia y osteoporosis en mujeres posmenopáusicas.
Aten Primaria, 35 (2005), pp. 342-347
[5.]
D. Hailey, L. Sampietro-Colom, D. Marshall, R. Rico, A. Granados, J. Asua.
The effectiveness of bone density measurement and associated treatments for prevention of fractures. An international collaborative review.
Int J Technol Assess Health Care, 14 (1998), pp. 237-254
[6.]
A. López García-Franco, P. Alonso-Coello, E. Bailón Buñoz, J. Landa-Goñi, M. Fuentes- Pujol, J. Ojuel-Solsona.
Actividades preventivas en el climaterio.
Aten Primaria, 36 (2005), pp. 102-130
[7.]
H.K. Genant, C. Cooper, G. Poor, I. Reid, G. Ehrlich, D. Kanis, et al.
Interim report and recommendations of the World Health Organization Task-Force for osteoporosis.
Osteoporos Int, 10 (1999), pp. 259-264
[8.]
WHO. Scientific group on the assessment of osteoporosis at primary health care level. Summary Meeting Report, Brussels, Belgium, May 5-7, 2004. World Health Organisation, 2007. Available from: www.who.int/entity/chp/topics/Osteoporosis.pdf.
[9.]
E. Brankin, C. Mitchell, R. Munro.
Closing the osteoporosis management gap in primary care: A secondary prevention of fracture programme.
Curr Med Res Opin, 21 (2005), pp. 475-482
[10.]
Risk assessment. Physician's Guide for the prevention and treatment of osteoporosis. Washington: National Osteoporosis Foundation; 2003.
[11.]
M. Gass, B. Dawson-Hugues.
Preventing osteoporosis-related fractures: an overview.
Am J Med, 119 (2006), pp. S3-S11
[12.]
J. González-Macías, F. Marín, J. Vila, A. Díez-Pérez, M. Abizanda, R. Álvarez, et al.
Investigadores del proyecto ECOSAP. Factores de riesgo de fractura osteoporótica en una serie de 5. 195 mujeres mayores de 65 años.
Med Clin (Barc), 123 (2004), pp. 85-89
[13.]
S. Schrager, M. Girard, M. Mundt.
Dietary calcium intake among women attending primary care clinics in Wisconsin.
Wisc Med J, 104 (2006), pp. 47-50
[14.]
Shea B, Wells G, Cranney A, Zytaruk N, Robinson V, Griffith L, et al. The Osteoporosis Methodology Group, and the Osteoporosis Research Advisory Group. Suplementos de calcio para la pérdida ósea en mujeres postmenopáusicas [Cochrane review translated]. In: La Biblioteca Cochrane Plus, 2006 Número 1.
[15.]
Avenell A, Gillespie WJ, Gillespie LD, O’Connell DL. Vitamina D y análogos para la prevención de fracturas asociadas con la osteoporosis senil y postmenopáusica [Cochrane review translated]. In: La Biblioteca Cochrane Plus, 2006 Número 1.
[16.]
M. Vaqueiro, M. Baré, E. Anton, E. Andreu, A. Moya, R. Sampere, et al.
[Hypovitaminosis D associated to low sun exposure in the population over 64 years old].
Med Clin (Barc), 129 (2007), pp. 287-291
[17.]
Y. Sato, J. Iwamoto, T. Kanoko, K. Satoh.
Amelioration of osteoporosis and hypovitaminosis D by sunlight exposure in hospitalized, elderly women with Alzheimer's disease: a randomized controlled trial.
J Bone Miner Res, 20 (2005), pp. 1327-1333
Copyright © 2009. Sociedad Española de Reumatología and Colegio Mexicano de Reumatología
Download PDF
Idiomas
Reumatología Clínica (English Edition)
Article options
Tools
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?