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        "titulo" => "Abstract"
        "resumen" => "<span class="elsevierStyleSectionTitle">Objective</span><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">To study the clinical and epidemiological characteristics of all adults patients as having synovial sarcoma in the Hospital Xeral-Calde &#40;Lugo&#41; between 2002 and 2006&#46;</p> <span class="elsevierStyleSectionTitle">Patients and method</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">We conducted a retrospective study of the case records of all adults patients diagnosed with synovial sarcoma from January 2002 through December 2006&#46; Patients were considered to be adults if they were more than 18&#46; In all cases a tissue-biopsy sample showing synovial sarcoma was required&#46; The Hospital Xeral-Calde is the only referral center for a population of almost 250 000 people&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Four cases &#40;3 women&#41; met the classification criteria for this study&#46; The mean age was 35 years old &#40;range&#44; 22&#8211;41&#41;&#46;</p><p id="spar0115" class="elsevierStyleSimplePara elsevierViewall">The most common presentation was a palpable mass &#40;mean&#44; 6&#46;7<span class="elsevierStyleHsp" style=""></span>cm&#41; associated with pain in lower extremities&#46; The mean delay for the diagnosis was 17 months&#44; but in one case has been noted as long as 2&#46;5 years&#46; Unlike the neck synovial sarcoma case&#44; a long delay in the diagnosis implied a major tumor size and a higher histological stage&#46;</p><p id="spar0125" class="elsevierStyleSimplePara elsevierViewall">The mean follow-up was 25&#46;5 months&#59; one patient died 1&#46;5 years after the diagnosis&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">The overall annual incidence rate of synovial sarcoma in the Lugo region between January 2002 and 2006 for the population older than 18 years was a minimum estimate 0&#46;32&#47;10&#46;5 Better physician awareness may contribute to the progressive increase in the recognition of this condition&#44; especially in young people presenting with palpable mass&#46; A long delay at the diagnosis implied a poor prognosis&#46;</p>"
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        "resumen" => "<span class="elsevierStyleSectionTitle">Objetivo</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">Estudiar las caracter&#237;sticas epidemiol&#243;gicas y cl&#237;nicas de todos los pacientes adultos diagnosticados de sarcoma sinovial &#40;SS&#41; en el per&#237;odo de 2002 a 2006 en el Hospital Xeral-Calde de Lugo&#46;</p> <span class="elsevierStyleSectionTitle">Pacientes y m&#233;todo</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">Estudio retrospectivo de todos los pacientes mayores de 18 a&#241;os diagnosticados mediante estudio de anatom&#237;a patol&#243;gica de SS desde enero de 2002 hasta diciembre de 2006&#46; Este hospital da asistencia sanitaria a 250&#46;000 habitantes&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0035" class="elsevierStyleSimplePara elsevierViewall">Un total de 4 casos &#40;3 mujeres&#41; cumpl&#237;an los criterios establecidos para este estudio&#44; con edades comprendidas entre los 22 y los 41 a&#241;os &#40;media de 35 a&#241;os&#41;&#46;</p><p id="spar0235" class="elsevierStyleSimplePara elsevierViewall">El motivo de consulta fue tumoraci&#243;n &#40;media de 6&#44;7cm&#41; y dolor predominantemente en las extremidades inferiores&#46; El retraso diagn&#243;stico promedio fue de 17 meses&#44; aunque en alg&#250;n caso se lleg&#243; a los 2&#44;5 a&#241;os&#46; Excepto para el caso de SS de localizaci&#243;n cervical&#44; un mayor retraso al diagn&#243;stico se correlacion&#243; con un mayor tama&#241;o del tumor y un estadio m&#225;s avanzado&#46;</p><p id="spar0335" class="elsevierStyleSimplePara elsevierViewall">El seguimiento medio de los enfermos fue de 25&#44;5 meses&#46; Un paciente falleci&#243; al cabo de un a&#241;o y medio del diagn&#243;stico&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0040" class="elsevierStyleSimplePara elsevierViewall">El promedio de incidencia m&#237;nima estimada de los SS en mayores de 18 a&#241;os en el &#225;rea de Lugo fue de 0&#44;32 por cada 105 habitantes al a&#241;o&#46; A pesar de su baja incidencia&#44; ante una persona joven que presenta una masa&#44; a veces dolorosa&#44; en las extremidades inferiores&#44; debe incluirse el SS en el diagn&#243;stico diferencial&#46; Un mayor &#237;ndice de sospecha por parte de los m&#233;dicos puede evitar un diagn&#243;stico tard&#237;o&#46;</p>"
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Vol. 5. Issue 5.
Pages 194-196 (September - October 2009)
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Vol. 5. Issue 5.
Pages 194-196 (September - October 2009)
Original article
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Synovial sarcomas in Lugo between 2002–2006
Sarcomas sinoviales en el área sanitaria de Lugo en el período de 2002 a 2006
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4636
Manuel Bravo-Péreza, Susana López-Lópezb, Alberto Miranda-Filloyc, Luisa Ibáñez-Martína, Luis Quevedo-Garcíaa, Carlos García-Porruac,
Corresponding author
cgporrua@hotmail.com

Corresponding author.
a Servicio de Cirugía Ortopédica y Traumatología, Hospital Xeral-Calde, Lugo, Spain
b Servicio de Urgencias, Hospital Xeral-Calde, Lugo, Spain
c Sección de Reumatología, Hospital Xeral-Calde, Lugo, Spain
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Article information
Abstract
Objective

To study the clinical and epidemiological characteristics of all adults patients as having synovial sarcoma in the Hospital Xeral-Calde (Lugo) between 2002 and 2006.

Patients and method

We conducted a retrospective study of the case records of all adults patients diagnosed with synovial sarcoma from January 2002 through December 2006. Patients were considered to be adults if they were more than 18. In all cases a tissue-biopsy sample showing synovial sarcoma was required. The Hospital Xeral-Calde is the only referral center for a population of almost 250 000 people.

Results

Four cases (3 women) met the classification criteria for this study. The mean age was 35 years old (range, 22–41).

The most common presentation was a palpable mass (mean, 6.7cm) associated with pain in lower extremities. The mean delay for the diagnosis was 17 months, but in one case has been noted as long as 2.5 years. Unlike the neck synovial sarcoma case, a long delay in the diagnosis implied a major tumor size and a higher histological stage.

The mean follow-up was 25.5 months; one patient died 1.5 years after the diagnosis.

Conclusions

The overall annual incidence rate of synovial sarcoma in the Lugo region between January 2002 and 2006 for the population older than 18 years was a minimum estimate 0.32/10.5 Better physician awareness may contribute to the progressive increase in the recognition of this condition, especially in young people presenting with palpable mass. A long delay at the diagnosis implied a poor prognosis.

Keywords:
Synovial sarcoma
Clinical features
Follow-up
Mortalit
Resumen
Objetivo

Estudiar las características epidemiológicas y clínicas de todos los pacientes adultos diagnosticados de sarcoma sinovial (SS) en el período de 2002 a 2006 en el Hospital Xeral-Calde de Lugo.

Pacientes y método

Estudio retrospectivo de todos los pacientes mayores de 18 años diagnosticados mediante estudio de anatomía patológica de SS desde enero de 2002 hasta diciembre de 2006. Este hospital da asistencia sanitaria a 250.000 habitantes.

Resultados

Un total de 4 casos (3 mujeres) cumplían los criterios establecidos para este estudio, con edades comprendidas entre los 22 y los 41 años (media de 35 años).

El motivo de consulta fue tumoración (media de 6,7cm) y dolor predominantemente en las extremidades inferiores. El retraso diagnóstico promedio fue de 17 meses, aunque en algún caso se llegó a los 2,5 años. Excepto para el caso de SS de localización cervical, un mayor retraso al diagnóstico se correlacionó con un mayor tamaño del tumor y un estadio más avanzado.

El seguimiento medio de los enfermos fue de 25,5 meses. Un paciente falleció al cabo de un año y medio del diagnóstico.

Conclusiones

El promedio de incidencia mínima estimada de los SS en mayores de 18 años en el área de Lugo fue de 0,32 por cada 105 habitantes al año. A pesar de su baja incidencia, ante una persona joven que presenta una masa, a veces dolorosa, en las extremidades inferiores, debe incluirse el SS en el diagnóstico diferencial. Un mayor índice de sospecha por parte de los médicos puede evitar un diagnóstico tardío.

Palabras clave:
Sarcoma sinovial
Características clínicas
Pronóstico
Mortalidad
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Copyright © 2009. Sociedad Española de Reumatología and Colegio Mexicano de Reumatología
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