array:23 [
  "pii" => "S2173574309701327"
  "issn" => "21735743"
  "doi" => "10.1016/S2173-5743(09)70132-7"
  "estado" => "S300"
  "fechaPublicacion" => "2009-11-01"
  "aid" => "70132"
  "copyright" => "Sociedad Española de Reumatología and Colegio Mexicano de Reumatología"
  "copyrightAnyo" => "2009"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "fla"
  "cita" => "Reumatol Clin. 2009;5:244-7"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 2152
    "formatos" => array:3 [
      "EPUB" => 42
      "HTML" => 1432
      "PDF" => 678
    ]
  ]
  "itemSiguiente" => array:18 [
    "pii" => "S2173574309701339"
    "issn" => "21735743"
    "doi" => "10.1016/S2173-5743(09)70133-9"
    "estado" => "S300"
    "fechaPublicacion" => "2009-11-01"
    "aid" => "70133"
    "copyright" => "Sociedad Española de Reumatología and Colegio Mexicano de Reumatología"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "fla"
    "cita" => "Reumatol Clin. 2009;5:248-51"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2072
      "formatos" => array:3 [
        "EPUB" => 43
        "HTML" => 1491
        "PDF" => 538
      ]
    ]
    "en" => array:10 [
      "idiomaDefecto" => true
      "titulo" => "Influence of the natural history of disease on a previous diagnosis in patients with gout"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "248"
          "paginaFinal" => "251"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Influencia de la historia natural de la enfermedad en el diagnóstico previo en pacientes con gota"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Fernando Pérez Ruiz, Jesús Ruiz López, Ana María Herrero Beites"
          "autores" => array:3 [
            0 => array:2 [
              "nombre" => "Fernando"
              "apellidos" => "Pérez Ruiz"
            ]
            1 => array:2 [
              "nombre" => "Jesús"
              "apellidos" => "Ruiz López"
            ]
            2 => array:2 [
              "nombre" => "Ana María"
              "apellidos" => "Herrero Beites"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574309701339?idApp=UINPBA00004M"
    "url" => "/21735743/0000000500000006/v1_201305061600/S2173574309701339/v1_201305061600/en/main.assets"
  ]
  "itemAnterior" => array:18 [
    "pii" => "S2173574309701315"
    "issn" => "21735743"
    "doi" => "10.1016/S2173-5743(09)70131-5"
    "estado" => "S300"
    "fechaPublicacion" => "2009-11-01"
    "aid" => "70131"
    "copyright" => "Sociedad Española de Reumatología and Colegio Mexicano de Reumatología"
    "documento" => "simple-article"
    "crossmark" => 0
    "subdocumento" => "edi"
    "cita" => "Reumatol Clin. 2009;5:241-3"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 1707
      "formatos" => array:3 [
        "EPUB" => 43
        "HTML" => 1253
        "PDF" => 411
      ]
    ]
    "en" => array:8 [
      "idiomaDefecto" => true
      "titulo" => "Economic evaluation of health interventions: the opportunity cost of not evaluating"
      "tienePdf" => "en"
      "tieneTextoCompleto" => 0
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "241"
          "paginaFinal" => "243"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Evaluación económica de intervenciones sanitarias: el coste de oportunidad de no evaluar"
        ]
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Jaume Puig-Junoy, Juan Oliva"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "Jaume"
              "apellidos" => "Puig-Junoy"
            ]
            1 => array:2 [
              "nombre" => "Juan"
              "apellidos" => "Oliva"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574309701315?idApp=UINPBA00004M"
    "url" => "/21735743/0000000500000006/v1_201305061600/S2173574309701315/v1_201305061600/en/main.assets"
  ]
  "en" => array:14 [
    "idiomaDefecto" => true
    "titulo" => "The joint hypermobility syndrome in a Cuban juvenile population"
    "tieneTextoCompleto" => 0
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "244"
        "paginaFinal" => "247"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Francisco M. Menéndez Alejo, Damaris Díaz Lazaga, Verena Torrez Cárdenas, Vicente Martínez Rodríguez"
        "autores" => array:4 [
          0 => array:4 [
            "nombre" => "Francisco M."
            "apellidos" => "Menéndez Alejo"
            "email" => array:2 [
              0 => "framenendez@infomed.sld.cu"
              1 => "menendez@infomed.sld.cu"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "Damaris"
            "apellidos" => "D&#237;az Lazaga"
          ]
          2 => array:2 [
            "nombre" => "Verena"
            "apellidos" => "Torrez C&#225;rdenas"
          ]
          3 => array:2 [
            "nombre" => "Vicente"
            "apellidos" => "Mart&#237;nez Rodr&#237;guez"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:1 [
            "entidad" => "Hospital General Docente Aleida Fernandez Chardiet&#44; Departamento de Cl&#237;nicas&#44; Servicio de Reumatolog&#237;a&#44; G&#252;ines&#44; Habana&#44; Cuba"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "S&#237;ndrome de hipermovilidad articular en una poblaci&#243;n juvenil cubana"
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2008-06-02"
    "fechaAceptado" => "2008-12-12"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec112222"
          "palabras" => array:5 [
            0 => "Joint hypermobility syndrome"
            1 => "Young population"
            2 => "Dysautonomia"
            3 => "Chronicle pain"
            4 => "Hematomas"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec112223"
          "palabras" => array:5 [
            0 => "S&#237;ndrome de hipermovilidad articular"
            1 => "Poblaci&#243;n joven"
            2 => "Disautonom&#237;a"
            3 => "Dolor cr&#243;nico"
            4 => "Hematomas"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">In order to review the rise in joint hypermobility syndrome&#44; identify the patterns associated with this diagnosis and correlate its most relevant symptoms&#44; we did a descriptive transversal analytic study in a group of 280 young people of both genders between 15 and 17 years of age&#46; A survey was carried out by the authors in order to get reach these objectives&#46; The data were analyzed by means of descriptive statistics and processed with the Epidat3&#46;1 software package&#46; Results are shown in charts&#46;</p> <span class="elsevierStyleSectionTitle">Results</span><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">The joint hypermobility syndrome &#40;JHS&#41; was diagnosed in 32 people &#40;11&#46;4&#37; of the population studied&#41; with mean age 15&#46;7 years&#44; predominance in the female sex and in the white skin group &#40;P<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>&#46;01&#41;&#46; Fifty-three point one percent of those patients with hypermobility presented skin lesions associated to hereditary diseases of the connective tissue&#59; among them the most relevant clinical sign was the presence of hematomas &#40;P<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;003&#41;&#46; Symptoms of dysautonomia were associated to JHS &#40;P<span class="elsevierStyleHsp" style=""></span>&#8804;<span class="elsevierStyleHsp" style=""></span>&#46;05&#41; and correlated positively with the presence of hematomas&#46; Moderate and severe chronic pain was also a feature of patients with the syndrome &#40;P<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>&#46;001&#41; and was correlated in a positive manner to the hematomas&#46;</p> <span class="elsevierStyleSectionTitle">Conclusions</span><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Vascular affection as demonstrated by the formation of hematomas was the skin lesion more important among young people with JHS in this study&#46; These lesions can be representative of the syndrome and a translate a larger damage at the connective tissue level&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Para investigar la frecuencia de aparici&#243;n del s&#237;ndrome de hipermovilidad articular &#40;SHA&#41;&#44; identificar los cuadros asociados a este diagn&#243;stico y correlacionar los s&#237;ntomas m&#225;s significativos&#44; se realiz&#243; un estudio descriptivo-anal&#237;tico en un grupo de 280 j&#243;venes de ambos sexos con edades comprendidas entre los 15 y los 17 a&#241;os&#46; Para la obtenci&#243;n de los objetivos se elabor&#243; por parte de los autores un modelo de encuesta&#46; Los datos se procesaron por estad&#237;stica descriptiva utilizando el programa Epidat 3&#46;1&#46; Los resultados se muestran en tablas confeccionadas al efecto&#46;</p> <span class="elsevierStyleSectionTitle">Resultados</span><p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">El SHA se diagnostic&#243; en 32 individuos &#40;11&#44;4&#37; de los encuestados&#41; con una media de edad de 15 a&#241;os&#44; predominio en el sexo femenino y en el grupo de poblaci&#243;n con color de piel blanca &#40;p<span class="elsevierStyleHsp" style=""></span>&#60;<span class="elsevierStyleHsp" style=""></span>0&#44;01&#41;&#46; El 53&#44;1&#37; de los hiperm&#243;viles present&#243; lesiones cut&#225;neas de las asociadas a las enfermedades hereditarias del tejido conjuntivo y&#44; entre ellas&#44; la presencia de los hematomas result&#243; significativa &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;003&#41;&#46; Los s&#237;ntomas de disautonom&#237;a se asociaron al SHA &#40;p<span class="elsevierStyleHsp" style=""></span>&#8804;<span class="elsevierStyleHsp" style=""></span>0&#44;05&#41; y se correlacionaron positivamente con los hematomas&#46; El dolor cr&#243;nico moderado y grave apareci&#243; en los individuos con el s&#237;ndrome &#40;p<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>0&#44;001&#41; y tambi&#233;n se correlacion&#243; en forma positiva con los hematomas&#46;</p> <span class="elsevierStyleSectionTitle">Conclusiones</span><p id="spar0030" class="elsevierStyleSimplePara elsevierViewall">La afectaci&#243;n vascular demostrada por la formaci&#243;n de hematomas fue el tipo de lesi&#243;n cut&#225;nea m&#225;s frecuente entre los hiperm&#243;viles j&#243;venes&#59; esta lesi&#243;n podr&#237;a estar representando una forma m&#225;s sintom&#225;tica del s&#237;ndrome y una mayor profundidad de da&#241;o a nivel de tejido conjuntivo&#46;</p>"
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:30 [
            0 => array:3 [
              "identificador" => "bib1"
              "etiqueta" => "1&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Klippel Dieppe Ferry"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "Primary Care Rheumatology"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "fecha" => "2000"
                        "editorial" => "Harcourt Publisher Limited"
                        "editorialLocalizacion" => "Mosby"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib2"
              "etiqueta" => "2&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Benign joint hypermobility in childhood"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "K&#46;J&#46; Murray"
                            1 => "P&#46; Woo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Rheumatology"
                        "fecha" => "2001"
                        "volumen" => "40"
                        "paginaInicial" => "489"
                        "paginaFinal" => "491"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11371655"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib3"
              "etiqueta" => "3&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Joint hypermobility and genetic collagen disorders&#58; Are they related&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46; Grahame"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Arch Disc Child"
                        "fecha" => "1999"
                        "volumen" => "80"
                        "paginaInicial" => "188"
                        "paginaFinal" => "191"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib4"
              "etiqueta" => "4&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Assessment of hypermobility"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "P&#46; Beighton"
                            1 => "R&#46; Grahame"
                            2 => "H&#46; Bird"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:5 [
                        "edicion" => "3rd ed&#46;"
                        "titulo" => "Hypermobility of joint"
                        "fecha" => "1999"
                        "editorial" => "Springer-Verlag"
                        "editorialLocalizacion" => "London"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib5"
              "etiqueta" => "5&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pain&#44; distress and joint hyperlaxity"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "R&#46; Grahame"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Joint Bone Spine"
                        "fecha" => "2000"
                        "volumen" => "67"
                        "paginaInicial" => "157"
                        "paginaFinal" => "163"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10875311"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib6"
              "etiqueta" => "6&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Is joint hypermobility related to anxiety in a non clinical population also&#63;"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "A&#46; Bulbena"
                            1 => "A&#46; Agullo"
                            2 => "G&#46; Pailhez"
                            3 => "R&#46; Martin-Santos"
                            4 => "M&#46; Porta"
                            5 => "J&#46; Guitar"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1176/appi.psy.45.5.432"
                      "Revista" => array:6 [
                        "tituloSerie" => "Psychosomatics"
                        "fecha" => "2004"
                        "volumen" => "45"
                        "paginaInicial" => "432"
                        "paginaFinal" => "437"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15345789"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            6 => array:3 [
              "identificador" => "bib7"
              "etiqueta" => "7&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Joint hypermobility in patient&#39;s with fibromialgya syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "M&#46; Acasuso D&#237;az"
                            1 => "E&#46; Collantes Estevez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:7 [
                        "tituloSerie" => "Arthritis Care Res"
                        "fecha" => "1998"
                        "volumen" => "11"
                        "paginaInicial" => "39"
                        "paginaFinal" => "42"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/9534492"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S152169420800051X"
                          "estado" => "S300"
                          "issn" => "15216942"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            7 => array:3 [
              "identificador" => "bib8"
              "etiqueta" => "8&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Hiperlaxitud e hipermovilidad articular en adolescentes"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "F&#46; Men&#233;ndez Alejo"
                            1 => "I&#46; Men&#233;ndez Alejo"
                            2 => "M&#46; Rodr&#237;guez Hern&#225;ndez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Mex Pediatr"
                        "fecha" => "1994"
                        "volumen" => "61"
                        "paginaInicial" => "188"
                        "paginaFinal" => "191"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            8 => array:3 [
              "identificador" => "bib9"
              "etiqueta" => "9&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The revised &#40;Brighton 1998&#41; criteria for the diagnosis of benign joint hypermobility syndrome BJHS"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "R&#46; Grahame"
                            1 => "H&#46;A&#46; Bird"
                            2 => "A&#46; Child"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Rheumatol"
                        "fecha" => "2000"
                        "volumen" => "27"
                        "paginaInicial" => "1777"
                        "paginaFinal" => "1779"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10914867"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            9 => array:3 [
              "identificador" => "bib10"
              "etiqueta" => "10&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Programa para an&#225;lisis epidemiol&#243;gico de datos tabulados"
                      "autores" => array:1 [
                        0 => array:2 [
                          "colaboracion" => "EPIDAT"
                          "etal" => false
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Libro" => array:3 [
                        "titulo" => "Versi&#243;n 3&#46;1"
                        "fecha" => "2006"
                        "editorial" => "OPS&#47;OMS"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            10 => array:3 [
              "identificador" => "bib11"
              "etiqueta" => "11&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "De la laxitud a la hipermovilidad articular"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "F&#46; Men&#233;ndez Alejo"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Revista Cubana de Reumatolog&#237;a"
                        "fecha" => "2005"
                        "volumen" => "VII"
                        "paginaInicial" => "7"
                        "paginaFinal" => "13"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            11 => array:3 [
              "identificador" => "bib12"
              "etiqueta" => "12&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Estudio de algunos rangos de movilidad articular y prevalencia del s&#237;ndrome benigno de hipermovilidad articular en estudiantes sanos de un colegio secundario de ciudad nueva"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46; Vera Carpio"
                            1 => "E&#46; Vera B&#233;jar"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Chil Reumat"
                        "fecha" => "1996"
                        "volumen" => "4"
                        "paginaInicial" => "13"
                        "paginaFinal" => "18"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            12 => array:3 [
              "identificador" => "bib13"
              "etiqueta" => "13&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "General joint laxity in 1845 Swedish school children of different ages and genders specific distribution"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46; Jansson"
                            1 => "K&#46;T&#46; Saarto"
                            2 => "S&#46; Werner"
                            3 => "P&#46; Reustrom"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Acts Paediatric"
                        "fecha" => "2004"
                        "volumen" => "93"
                        "paginaInicial" => "1202"
                        "paginaFinal" => "1205"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            13 => array:3 [
              "identificador" => "bib14"
              "etiqueta" => "14&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Joint hypermobility in south Indian children"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "V&#46; Subramanyan"
                            1 => "K&#46;U&#46; Janaki"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Indian Paediatr"
                        "fecha" => "1996"
                        "volumen" => "33"
                        "paginaInicial" => "771"
                        "paginaFinal" => "772"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            14 => array:3 [
              "identificador" => "bib15"
              "etiqueta" => "15&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Joint hypermobility syndrome among undergraduate students"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "B&#46;C&#46; Didia"
                            1 => "D&#46;V&#46; Dapper"
                            2 => "S&#46; Boboye"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "East Afr MED J"
                        "fecha" => "2002"
                        "volumen" => "79"
                        "paginaInicial" => "80"
                        "paginaFinal" => "81"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12380882"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            15 => array:3 [
              "identificador" => "bib16"
              "etiqueta" => "16&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Laxitud articular&#58; prevalencia y relaci&#243;n con dolor musculoesquel&#233;tico"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "J&#46; Inocencio-Arocena"
                            1 => "I&#46; Oca&#241;a Casas"
                            2 => "L&#46; Benito Ortiz"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Anales Pediatria"
                        "fecha" => "2004"
                        "volumen" => "61"
                        "paginaInicial" => "162"
                        "paginaFinal" => "166"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            16 => array:3 [
              "identificador" => "bib17"
              "etiqueta" => "17&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "The prevalence of joint hypermobility among high school students"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "V&#46; Seckin"
                            1 => "B&#46;S&#46; Tur"
                            2 => "O&#46; Yilmaz"
                            3 => "I&#46; Yaqci"
                            4 => "H&#46; Bodur"
                            5 => "T&#46; Aracil"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00296-003-0434-9"
                      "Revista" => array:6 [
                        "tituloSerie" => "Rheumatol Int"
                        "fecha" => "2005"
                        "volumen" => "25"
                        "paginaInicial" => "260"
                        "paginaFinal" => "263"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/14745505"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            17 => array:3 [
              "identificador" => "bib18"
              "etiqueta" => "18&#46;"
              "referencia" => array:1 [
                0 => array:1 [
                  "referenciaCompleta" => "La laxitud articular&#46; In&#58; Rotes Querol J&#46; Reumatolog&#237;a cl&#237;nica&#46; Barcelona&#58; Espaxs&#59; 1983&#46; p&#46; 5"
                ]
              ]
            ]
            18 => array:3 [
              "identificador" => "bib19"
              "etiqueta" => "19&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Prognosis of non-specific musculoesqueletal pain in preadolescents&#58; A prospective 4 years follow-up study of adolescence"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A&#46; El&#8211;Metwally"
                            1 => "J&#46;J&#46; Salminen"
                            2 => "A&#46; Auvinen"
                            3 => "H&#46; Kautianen"
                            4 => "M&#46; Mikkelson"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.pain.2009.05.026"
                      "Revista" => array:6 [
                        "tituloSerie" => "Pain"
                        "fecha" => "2004"
                        "paginaInicial" => "110"
                        "paginaFinal" => "113"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/19560271"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0091674901976651"
                          "estado" => "S300"
                          "issn" => "00916749"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            19 => array:3 [
              "identificador" => "bib20"
              "etiqueta" => "20&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pain and musculoskeletal pain syndromes in adolescents"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "A&#46;L&#46; Zapata"
                            1 => "A&#46;J&#46; Moraes"
                            2 => "C&#46; Leone"
                            3 => "U&#46; Doria Filho"
                            4 => "C&#46;A&#46; Silva"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Adolescent Health"
                        "fecha" => "2006"
                        "volumen" => "38"
                        "paginaInicial" => "769"
                        "paginaFinal" => "771"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            20 => array:3 [
              "identificador" => "bib21"
              "etiqueta" => "21&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pediatric generalized joint hypermobility with and without musculoskeletal complaints&#58; A localized or systemic disorders"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "R&#46;H&#46; Engelber"
                            1 => "R&#46;A&#46; Bank"
                            2 => "R&#46;J&#46; Sackers"
                            3 => "P&#46;J&#46; Helder"
                            4 => "F&#46; Beemer"
                            5 => "C&#46; Uiterwal"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Pediatrics"
                        "fecha" => "2003"
                        "volumen" => "3"
                        "paginaInicial" => "248"
                        "paginaFinal" => "254"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            21 => array:3 [
              "identificador" => "bib22"
              "etiqueta" => "22&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Tenascin-x&#44; a candidate gene for BJHS and hypermobility type Ehler&#8211;Danlos syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46;C&#46; Zweers"
                            1 => "M&#46; Kusharekova"
                            2 => "J&#46; Schalkwijk"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1136/ard.2004.026559"
                      "Revista" => array:7 [
                        "tituloSerie" => "Ann Rheum Dis"
                        "fecha" => "2005"
                        "volumen" => "64"
                        "paginaInicial" => "504"
                        "paginaFinal" => "505"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/15708907"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S1699258X12001350"
                          "estado" => "S300"
                          "issn" => "1699258X"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            22 => array:3 [
              "identificador" => "bib23"
              "etiqueta" => "23&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Joint hypermobility and skin elasticity&#58; The hereditary disorders of connective tissue"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "A&#46;J&#46; Hakim"
                            1 => "A&#46; Sahota"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.clindermatol.2006.07.013"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Dermatol"
                        "fecha" => "2006"
                        "volumen" => "24"
                        "paginaInicial" => "521"
                        "paginaFinal" => "523"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17113970"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            23 => array:3 [
              "identificador" => "bib24"
              "etiqueta" => "24&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Importancia de la hipermovilidad articular como causa frecuente de morbilidad&#44; no solo musculoesquel&#233;tica sino tambi&#233;n sist&#233;mica&#58; criterios diagn&#243;sticos"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "J&#46; Bravo Silva"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Rev Chil Reumatol"
                        "fecha" => "2003"
                        "volumen" => "19"
                        "paginaInicial" => "33"
                        "paginaFinal" => "38"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            24 => array:3 [
              "identificador" => "bib25"
              "etiqueta" => "25&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Dysautonomia in the joint hypermobility syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "Y&#46; Gazit"
                            1 => "A&#46;M&#46; Nahir"
                            2 => "R&#46; Grahame"
                            3 => "G&#46; Jacob"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Med"
                        "fecha" => "2003"
                        "volumen" => "115"
                        "paginaInicial" => "33"
                        "paginaFinal" => "40"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12867232"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            25 => array:3 [
              "identificador" => "bib26"
              "etiqueta" => "26&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Autonomic dysfunction in multiple sclerosis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:2 [
                            0 => "C&#46;A&#46; Haensch"
                            1 => "J&#46; Jorq"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "J Neurol"
                        "fecha" => "2006"
                        "volumen" => "253"
                        "paginaInicial" => "13"
                        "paginaFinal" => "19"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            26 => array:3 [
              "identificador" => "bib27"
              "etiqueta" => "27&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Autonomic symptoms during childhood partial epileptic seizures"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46; Fogarasi"
                            1 => "J&#46; Janszky"
                            2 => "I&#46; Tuxhorn"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Epilepsic"
                        "fecha" => "2006"
                        "volumen" => "47"
                        "paginaInicial" => "584"
                        "paginaFinal" => "588"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            27 => array:3 [
              "identificador" => "bib28"
              "etiqueta" => "28&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Fibromialgya as a sympathetically maintened pain syndrome"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46; Mart&#237;nez Lavin"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Current Pain and Headache Report"
                        "fecha" => "2004"
                        "volumen" => "8"
                        "paginaInicial" => "385"
                        "paginaFinal" => "389"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            28 => array:3 [
              "identificador" => "bib29"
              "etiqueta" => "29&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Vascular tone in adolescens with autonomic vascular dysfunction of hypotensive tipe according to the data of tetrapolar rheovasography"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "V&#46;M&#46; Buriak"
                            1 => "I&#46;V&#46; Prokhorov"
                            2 => "O&#46;M&#46; Plisa"
                            3 => "B&#46;I&#46; Rozhonov"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "Lik Sprava"
                        "fecha" => "2003"
                        "volumen" => "7"
                        "paginaInicial" => "45"
                        "paginaFinal" => "48"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18668711"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            29 => array:3 [
              "identificador" => "bib30"
              "etiqueta" => "30&#46;"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Epidemiology of general joint hypermovility and basis for the proposed criteria for the benign joint hypermobility syndrome&#58; Review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "L&#46; Rewvig"
                            1 => "D&#46;U&#46; Jensen"
                            2 => "R&#46;C&#46; Ward"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:6 [
                        "tituloSerie" => "J Rheumatol"
                        "fecha" => "2007"
                        "volumen" => "34"
                        "paginaInicial" => "804"
                        "paginaFinal" => "809"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17407233"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735743/0000000500000006/v1_201305061600/S2173574309701327/v1_201305061600/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "17338"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Original Article"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735743/0000000500000006/v1_201305061600/S2173574309701327/v1_201305061600/en/main.pdf?idApp=UINPBA00004M&text.app=https://reumatologiaclinica.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574309701327?idApp=UINPBA00004M"
]
Share
Journal Information
Vol. 5. Issue 6.
Pages 244-247 (November - December 2009)
Share
Share
Download PDF
More article options
Vol. 5. Issue 6.
Pages 244-247 (November - December 2009)
Full text access
The joint hypermobility syndrome in a Cuban juvenile population
Síndrome de hipermovilidad articular en una población juvenil cubana
Visits
5112
Francisco M. Menéndez Alejo
Corresponding author
, Damaris Díaz Lazaga, Verena Torrez Cárdenas, Vicente Martínez Rodríguez
Hospital General Docente Aleida Fernandez Chardiet, Departamento de Clínicas, Servicio de Reumatología, Güines, Habana, Cuba
This item has received
Article information
Abstract

In order to review the rise in joint hypermobility syndrome, identify the patterns associated with this diagnosis and correlate its most relevant symptoms, we did a descriptive transversal analytic study in a group of 280 young people of both genders between 15 and 17 years of age. A survey was carried out by the authors in order to get reach these objectives. The data were analyzed by means of descriptive statistics and processed with the Epidat3.1 software package. Results are shown in charts.

Results

The joint hypermobility syndrome (JHS) was diagnosed in 32 people (11.4% of the population studied) with mean age 15.7 years, predominance in the female sex and in the white skin group (P<.01). Fifty-three point one percent of those patients with hypermobility presented skin lesions associated to hereditary diseases of the connective tissue; among them the most relevant clinical sign was the presence of hematomas (P=.003). Symptoms of dysautonomia were associated to JHS (P.05) and correlated positively with the presence of hematomas. Moderate and severe chronic pain was also a feature of patients with the syndrome (P=.001) and was correlated in a positive manner to the hematomas.

Conclusions

Vascular affection as demonstrated by the formation of hematomas was the skin lesion more important among young people with JHS in this study. These lesions can be representative of the syndrome and a translate a larger damage at the connective tissue level.

Keywords:
Joint hypermobility syndrome
Young population
Dysautonomia
Chronicle pain
Hematomas
Resumen

Para investigar la frecuencia de aparición del síndrome de hipermovilidad articular (SHA), identificar los cuadros asociados a este diagnóstico y correlacionar los síntomas más significativos, se realizó un estudio descriptivo-analítico en un grupo de 280 jóvenes de ambos sexos con edades comprendidas entre los 15 y los 17 años. Para la obtención de los objetivos se elaboró por parte de los autores un modelo de encuesta. Los datos se procesaron por estadística descriptiva utilizando el programa Epidat 3.1. Los resultados se muestran en tablas confeccionadas al efecto.

Resultados

El SHA se diagnosticó en 32 individuos (11,4% de los encuestados) con una media de edad de 15 años, predominio en el sexo femenino y en el grupo de población con color de piel blanca (p<0,01). El 53,1% de los hipermóviles presentó lesiones cutáneas de las asociadas a las enfermedades hereditarias del tejido conjuntivo y, entre ellas, la presencia de los hematomas resultó significativa (p=0,003). Los síntomas de disautonomía se asociaron al SHA (p0,05) y se correlacionaron positivamente con los hematomas. El dolor crónico moderado y grave apareció en los individuos con el síndrome (p=0,001) y también se correlacionó en forma positiva con los hematomas.

Conclusiones

La afectación vascular demostrada por la formación de hematomas fue el tipo de lesión cutánea más frecuente entre los hipermóviles jóvenes; esta lesión podría estar representando una forma más sintomática del síndrome y una mayor profundidad de daño a nivel de tejido conjuntivo.

Palabras clave:
Síndrome de hipermovilidad articular
Población joven
Disautonomía
Dolor crónico
Hematomas
Full text is only aviable in PDF
References
[1.]
Primary Care Rheumatology.
Klippel Dieppe Ferry.
Harcourt Publisher Limited, (2000),
[2.]
K.J. Murray, P. Woo.
Benign joint hypermobility in childhood.
Rheumatology, 40 (2001), pp. 489-491
[3.]
R. Grahame.
Joint hypermobility and genetic collagen disorders: Are they related?.
Arch Disc Child, 80 (1999), pp. 188-191
[4.]
P. Beighton, R. Grahame, H. Bird.
Assessment of hypermobility.
Hypermobility of joint, 3rd ed., Springer-Verlag, (1999),
[5.]
R. Grahame.
Pain, distress and joint hyperlaxity.
Joint Bone Spine, 67 (2000), pp. 157-163
[6.]
A. Bulbena, A. Agullo, G. Pailhez, R. Martin-Santos, M. Porta, J. Guitar, et al.
Is joint hypermobility related to anxiety in a non clinical population also?.
Psychosomatics, 45 (2004), pp. 432-437
[7.]
M. Acasuso Díaz, E. Collantes Estevez.
Joint hypermobility in patient's with fibromialgya syndrome.
Arthritis Care Res, 11 (1998), pp. 39-42
[8.]
F. Menéndez Alejo, I. Menéndez Alejo, M. Rodríguez Hernández.
Hiperlaxitud e hipermovilidad articular en adolescentes.
Rev Mex Pediatr, 61 (1994), pp. 188-191
[9.]
R. Grahame, H.A. Bird, A. Child.
The revised (Brighton 1998) criteria for the diagnosis of benign joint hypermobility syndrome BJHS.
J Rheumatol, 27 (2000), pp. 1777-1779
[10.]
EPIDAT.
Programa para análisis epidemiológico de datos tabulados.
Versión 3.1, OPS/OMS, (2006),
[11.]
F. Menéndez Alejo.
De la laxitud a la hipermovilidad articular.
Revista Cubana de Reumatología, VII (2005), pp. 7-13
[12.]
C. Vera Carpio, E. Vera Béjar.
Estudio de algunos rangos de movilidad articular y prevalencia del síndrome benigno de hipermovilidad articular en estudiantes sanos de un colegio secundario de ciudad nueva.
Rev Chil Reumat, 4 (1996), pp. 13-18
[13.]
A. Jansson, K.T. Saarto, S. Werner, P. Reustrom.
General joint laxity in 1845 Swedish school children of different ages and genders specific distribution.
Acts Paediatric, 93 (2004), pp. 1202-1205
[14.]
V. Subramanyan, K.U. Janaki.
Joint hypermobility in south Indian children.
Indian Paediatr, 33 (1996), pp. 771-772
[15.]
B.C. Didia, D.V. Dapper, S. Boboye.
Joint hypermobility syndrome among undergraduate students.
East Afr MED J, 79 (2002), pp. 80-81
[16.]
J. Inocencio-Arocena, I. Ocaña Casas, L. Benito Ortiz.
Laxitud articular: prevalencia y relación con dolor musculoesquelético.
Anales Pediatria, 61 (2004), pp. 162-166
[17.]
V. Seckin, B.S. Tur, O. Yilmaz, I. Yaqci, H. Bodur, T. Aracil.
The prevalence of joint hypermobility among high school students.
Rheumatol Int, 25 (2005), pp. 260-263
[18.]
La laxitud articular. In: Rotes Querol J. Reumatología clínica. Barcelona: Espaxs; 1983. p. 5
[19.]
A. El–Metwally, J.J. Salminen, A. Auvinen, H. Kautianen, M. Mikkelson.
Prognosis of non-specific musculoesqueletal pain in preadolescents: A prospective 4 years follow-up study of adolescence.
[20.]
A.L. Zapata, A.J. Moraes, C. Leone, U. Doria Filho, C.A. Silva.
Pain and musculoskeletal pain syndromes in adolescents.
J Adolescent Health, 38 (2006), pp. 769-771
[21.]
R.H. Engelber, R.A. Bank, R.J. Sackers, P.J. Helder, F. Beemer, C. Uiterwal.
Pediatric generalized joint hypermobility with and without musculoskeletal complaints: A localized or systemic disorders.
Pediatrics, 3 (2003), pp. 248-254
[22.]
M.C. Zweers, M. Kusharekova, J. Schalkwijk.
Tenascin-x, a candidate gene for BJHS and hypermobility type Ehler–Danlos syndrome.
Ann Rheum Dis, 64 (2005), pp. 504-505
[23.]
A.J. Hakim, A. Sahota.
Joint hypermobility and skin elasticity: The hereditary disorders of connective tissue.
Clin Dermatol, 24 (2006), pp. 521-523
[24.]
J. Bravo Silva.
Importancia de la hipermovilidad articular como causa frecuente de morbilidad, no solo musculoesquelética sino también sistémica: criterios diagnósticos.
Rev Chil Reumatol, 19 (2003), pp. 33-38
[25.]
Y. Gazit, A.M. Nahir, R. Grahame, G. Jacob.
Dysautonomia in the joint hypermobility syndrome.
Am J Med, 115 (2003), pp. 33-40
[26.]
C.A. Haensch, J. Jorq.
Autonomic dysfunction in multiple sclerosis.
J Neurol, 253 (2006), pp. 13-19
[27.]
A. Fogarasi, J. Janszky, I. Tuxhorn.
Autonomic symptoms during childhood partial epileptic seizures.
Epilepsic, 47 (2006), pp. 584-588
[28.]
M. Martínez Lavin.
Fibromialgya as a sympathetically maintened pain syndrome.
Current Pain and Headache Report, 8 (2004), pp. 385-389
[29.]
V.M. Buriak, I.V. Prokhorov, O.M. Plisa, B.I. Rozhonov.
Vascular tone in adolescens with autonomic vascular dysfunction of hypotensive tipe according to the data of tetrapolar rheovasography.
Lik Sprava, 7 (2003), pp. 45-48
[30.]
L. Rewvig, D.U. Jensen, R.C. Ward.
Epidemiology of general joint hypermovility and basis for the proposed criteria for the benign joint hypermobility syndrome: Review of the literature.
J Rheumatol, 34 (2007), pp. 804-809
Copyright © 2009. Sociedad Española de Reumatología and Colegio Mexicano de Reumatología
Download PDF
Idiomas
Reumatología Clínica (English Edition)
Article options
Tools
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?