TY - JOUR T1 - Association between fibromyalgia syndrome clinical severity and body composition. A principal component analysis JO - Reumatología Clínica T2 - AU - Álvarez-Nemegyei,José AU - Pacheco-Pantoja,Elda Leonor AU - Olán-Centeno,Lililana Judith AU - Angulo-Ramírez,Angélica AU - Rodríguez-Magaña,Fernanda Elizabeth AU - Aranda-Muiña,José Fernando SN - 1699258X M3 - 10.1016/j.reuma.2021.09.004 DO - 10.1016/j.reuma.2021.09.004 UR - https://reumatologiaclinica.org/es-association-between-fibromyalgia-syndrome-clinical-articulo-S1699258X21002254 AB - IntroductionThe type of body composition modulates the severity of some musculoskeletal conditions, in fibromyalgia syndrome (FMS), this type of association remains relatively unexplored. ObjectiveTo analyze the association between the type of body composition and FMS using Principal Component Analysis (PCA). The FMS clinical outcome measures were: Symptom Severity Scale (SSS), Widespread Pain Index (WPI; and Fibromyalgia Impact Questionnaire (FIQ). MethodsForty-three women with FMS (ACR 2010 criteria) were clinically and anthropometrically evaluated. The anthropometric data were integrated into two indicators using a PCA methodology (PCA-Fat and PCA-muscle). Additionally, the patients were classified into high and low categories for each clinical indicator, which were used as dependent variables in binomial logistic regression (BLR) models. ResultsWe found a positive correlation between PCA-Fat with WPI (r=0.326, P=.043) and FIQ (r=0.325, P=.044), and negative correlation (r=−0.384, P=.013) between PCA-muscle and SSS. In the BLR analysis, PCA-Fat was a significant predictor for high WPI (OR=2.477, P=.038); while for high SSS, PCA-muscle (OR=0.303, P=.009) was an inversely significant predictor. ConclusionsThe results suggest that the volume of fat mass can negatively modulate the severity of FMS. We propose that the evaluation of body composition should be a basic element for the clinical approach of patients with FMS. ER -