TY - JOUR T1 - Systemic lupus erythematosus myocarditis after COVID-19 vaccination JO - Reumatología Clínica T2 - AU - Sogbe,Miguel AU - Blanco-Di Matteo,Andrés AU - Di Frisco,I. Madeleine AU - Bastidas,Juan Fernando AU - Salterain,Nahikari AU - Gavira,Juan José SN - 1699258X M3 - 10.1016/j.reuma.2022.06.003 DO - 10.1016/j.reuma.2022.06.003 UR - https://reumatologiaclinica.org/es-systemic-lupus-erythematosus-myocarditis-after-articulo-S1699258X22001553 AB - IntroductionCases of acute myocarditis have been after administration of the BNT162b2 and Ad26.COV2.S vaccine. ObjectiveDescribe another possible mechanism of myocarditis after COVID-19 vaccination. Case presentationWe describe the clinical case of a 72-year-old female with pleuritic chest pain one week after the third of the BNT162b2 mRNA vaccine. Serological tests for cardiotropic pathogens were negative, and autoimmunity screening was positive with anti-nuclear antibody (ANA) in 1:160 dilution, Anti-double-stranded DNA (anti-dsDNA), and anti-histone antibodies. 18F-fluoro-deoxy-glucose (FDG) positron emission tomography/computed tomography (PET/CT) showed a focal myocardial and pericardial inflammatory process in the cardiac apex. Results and discussionSystemic lupus erythematosus (SLE) diagnosis was made with myocardial affection. As far as we know, this is the first report of a case of lupus myocarditis after the COVID-19 vaccine. ConclusionGiven the pathogenic rationales, the association between SLE and myocarditis should be considered. ER -