Clinical research studyComorbidities of Gout and Hyperuricemia in the US General Population: NHANES 2007-2008
Section snippets
Study Population
The NHANES studies are designed to assess the health and nutritional status of adults and children in the US. These studies are based on a representative sample of the noninstitutionalized US civilian population that is selected using a multistage, stratified sampling design. The survey is unique in that it combines interviews, physical examinations, and various laboratory data. After a home interview, participants were invited to attend examination sessions where blood and urine specimens were
Comorbidities of Gout in the US in 2007-2008
In the NHANES 2007-2008, the mean age was 47 years, 48.2% of subjects were male, and 69.4% were white. Overall, 3.9% of US adults reported a physician or health professional diagnosis of gout. Among these individuals with gout, 74% (6.1 million) had hypertension, 71% (5.5 million) had chronic kidney disease stage ≥2, 53% (4.3 million) were obese, 26% (2.1 million) had diabetes, 24% (2.0 million) had nephrolithiasis, 14% (1.2 million) had myocardial infarction, 11% (0.9 million) had heart
Discussion
In this recent, nationally representative sample of US men and women, we found that the prevalence of comorbidities of gout was substantial. Approximately 74% of US adults with gout had hypertension, 71% had chronic kidney disease stage ≥2, 53% were obese, 26% had diabetes, 24% had nephrolithiasis, 14% had a myocardial infarction, and 11% had heart failure. These prevalences were 2-3 times higher than among those without gout. Correspondingly, we found that with increasing levels of
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Funding: This research was supported by Takeda Pharmaceuticals International, Inc.
Conflict of Interest: Dr Zhu has nothing to disclose. Dr Pandya is an employee of Takeda Pharmaceuticals International, Inc. Dr Choi has received research funding for other projects from Takeda Pharmaceuticals and has served on advisory boards for Takeda Pharmaceuticals, URL Pharma, and Savient Pharmaceuticals.
Authorship: All authors had access to the data and a role in writing the manuscript.