Lupus mesenteric vasculitis: Clinical features and associated factors for the recurrence and prognosis of disease
Section snippets
Patients
A retrospective review of the medical records between January 2002 and December 2011 was performed at the First Affiliated Hospital of Sun Yat-sen University. All together, 3823 patients were classified as having SLE who fulfilled at least 4 of the 1997 American College of Rheumatology (ACR) revised classification criteria for SLE [7]. Among these SLE patients, 97 had a dual simultaneous diagnosis of LMV according to the following inclusion criteria [8], [9]: (1) clinical evidence of
Clinical and demographic characteristics
Table 1 shows the clinical and demographic characteristics of the patients. Among the 97 patients with LMV, 47 (48.5%) presented with acute abdominal pain as the initial symptom of SLE. The median time between the onset of SLE and LMV was 0.5 months (ranging from 0 to 240 months). Abdominal pain was the most common symptom (88/97, 90.7%) and abdominal distension was the most common physical sign (68/97, 70.1%). CT scans indicated enteritis, and cystitis occurred concomitantly with lupus in 22
Discussion
The manifestation of LMV varies from mild, nonspecific symptoms to severe abdominal pain mimicking acute surgical abdomen. Its prevalence ranges from 0.2% to 9.7% in SLE patients and from 29% to 65% in patients presenting with acute abdominal pain [4]. In the current study, the prevalence of LMV was 2.5% of hospitalized lupus patients and 49.5% among those initially presented with acute abdominal pain, which was in accordance with other reports [2], [3], [6], [24]. The median SLE duration was
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This work was supported by the Guangdong Provincial Science and Technology Foundations, China (2009B030801098, 2011B050300009, 2008B080703015, 2005B30701001, and 2007B031500007); Guangdong Natural Science Foundation (S2012010009075); and National Natural Science Foundations of China (81102270 and 81102270).