Severe flare of Behcet's disease with intense mucucutaneous manifestations
Brote severo de la enfermedad de Behçet con manifestaciones mucocutáneas intensas
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Martín, Elisabeth Mateo, Carlos Monteagudo, Esperanza Jordá" "autores" => array:4 [ 0 => array:4 [ "nombre" => "José M." "apellidos" => "Martín" "email" => array:1 [ 0 => "jmmart@eresmas.com" ] "referencia" => array:2 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">¿</span>" "identificador" => "cor0005" ] ] ] 1 => array:3 [ "nombre" => "Elisabeth" "apellidos" => "Mateo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] ] ] 2 => array:3 [ "nombre" => "Carlos" "apellidos" => "Monteagudo" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] ] 3 => array:3 [ "nombre" => "Esperanza" "apellidos" => "Jordá" "referencia" => array:1 [ 0 => array:2 [ "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] ] ] ] "afiliaciones" => array:3 [ 0 => array:3 [ "entidad" => "Servicios de Dermatología, Hospital Clínico Universitario, Valencia, Spain" "etiqueta" => "<span class="elsevierStyleSup">a</span>" "identificador" => "aff0005" ] 1 => array:3 [ "entidad" => "Medicina Interna, Hospital General Universitario, Valencia, Spain" "etiqueta" => "<span class="elsevierStyleSup">b</span>" "identificador" => "aff0010" ] 2 => array:3 [ "entidad" => "Anatomía Patológica, Hospital Clínico Universitario, Valencia, Spain" "etiqueta" => "<span class="elsevierStyleSup">c</span>" "identificador" => "aff0015" ] ] "correspondencia" => array:1 [ 0 => array:3 [ "identificador" => "cor0005" "etiqueta" => "⁎" "correspondencia" => "Corresponding author." ] ] ] ] "titulosAlternativos" => array:1 [ "es" => array:1 [ "titulo" => "Brote severo de la enfermedad de Behçet con manifestaciones mucocutáneas intensas" ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2009-11-02" "fechaAceptado" => "2010-05-05" "PalabrasClave" => array:2 [ "en" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Keywords" "identificador" => "xpalclavsec112568" "palabras" => array:2 [ 0 => "Cytomegalovirus" 1 => "Behcet's disease" ] ] ] "es" => array:1 [ 0 => array:4 [ "clase" => "keyword" "titulo" => "Palabras clave" "identificador" => "xpalclavsec112569" "palabras" => array:2 [ 0 => "Citomegalovirus" 1 => "Enfermedad de Behçet" ] ] ] ] "tieneResumen" => true "resumen" => array:2 [ "en" => array:2 [ "titulo" => "Abstract" "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Behcet's disease is a multisystemic inflammatory disease with various manifestations at the skin level, especially in the form of acne-like lesions or erythema nodosum. Susceptibility to this disease is strongly linked to the presence of the HLA_B51 allele, although certain environmental factors such as infectious agents have also been implicated in its pathogenesis. We present the case of a patient with Behcet's disease who developed a severe flare characterized by lesions similar to those seen in Sweet's syndrome. Histologically we observed granulomatous vasculitis.</p>" ] "es" => array:2 [ "titulo" => "Resumen" "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">La enfermedad de Behcet es un trastorno inflamatorio multisistemico que se manifiesta de forma muy variada a nivel cutaneo, especialmente en forma de lesiones acneiformes o de eritema nodoso. La susceptibilidad a padecer esta enfermedad se halla fuertemente ligada con la presencia del alelo HLA-B51, aunque determinados factores ambientales como agentes infecciosos tambien se han implicado en la patogenesis. Presentamos el caso de una paciente con una enfermedad de Behcet que desarrollo un brote severo con lesiones cutaneas analogas a las que se aprecian en el sindrome de Sweet. Histologicamente se apreciaron fenomenos de vasculitis granulomatosa.</p>" ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:12 [ 0 => array:3 [ "identificador" => "bib1" "etiqueta" => "1." "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "Behçet's disease" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:4 [ 0 => "T. Sakane" 1 => "M. Takeno" 2 => "N. Suzuki" 3 => "G. 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| 2016 July | 15 | 12 | 27 |
| 2016 April | 1 | 0 | 1 |
| 2016 February | 2 | 0 | 2 |
| 2016 January | 4 | 0 | 4 |
| 2015 December | 5 | 0 | 5 |
| 2015 October | 2 | 11 | 13 |
| 2015 September | 1 | 0 | 1 |
| 2015 August | 1 | 0 | 1 |
| 2015 July | 15 | 4 | 19 |
| 2015 June | 23 | 43 | 66 |
| 2015 May | 33 | 18 | 51 |
| 2015 April | 27 | 17 | 44 |
| 2015 March | 12 | 17 | 29 |
| 2015 February | 24 | 20 | 44 |
| 2015 January | 18 | 26 | 44 |
| 2014 December | 23 | 17 | 40 |
| 2014 November | 16 | 17 | 33 |
| 2014 October | 20 | 10 | 30 |
| 2014 September | 14 | 10 | 24 |
| 2014 August | 20 | 19 | 39 |
| 2014 July | 20 | 12 | 32 |
| 2014 June | 54 | 17 | 71 |
| 2014 May | 39 | 24 | 63 |
| 2014 April | 26 | 15 | 41 |
| 2014 March | 36 | 21 | 57 |
| 2014 February | 25 | 15 | 40 |
| 2014 January | 26 | 21 | 47 |
| 2013 December | 29 | 15 | 44 |
| 2013 November | 21 | 13 | 34 |
| 2013 October | 34 | 17 | 51 |
| 2013 September | 23 | 14 | 37 |
| 2013 August | 31 | 29 | 60 |
| 2013 July | 26 | 19 | 45 |
| 2013 June | 24 | 26 | 50 |
| 2013 May | 21 | 13 | 34 |
| 2013 April | 24 | 8 | 32 |
| 2013 March | 20 | 15 | 35 |
| 2013 February | 16 | 14 | 30 |
| 2013 January | 11 | 13 | 24 |
| 2012 December | 18 | 10 | 28 |
| 2012 November | 7 | 14 | 21 |
| 2012 October | 14 | 8 | 22 |
| 2012 September | 9 | 5 | 14 |
| 2012 June | 1 | 0 | 1 |
| 2012 April | 5 | 0 | 5 |
| 2012 March | 1 | 0 | 1 |
| 2012 February | 2 | 0 | 2 |
| 2012 January | 3 | 0 | 3 |
| 2011 December | 6 | 0 | 6 |
| 2011 November | 6 | 0 | 6 |
| 2011 October | 2 | 0 | 2 |
| 2011 September | 1 | 0 | 1 |
| 2011 August | 3 | 0 | 3 |
| 2011 July | 2 | 0 | 2 |
| 2011 June | 3 | 0 | 3 |
| 2011 May | 2 | 0 | 2 |
| 2011 April | 2 | 0 | 2 |
| 2011 March | 3 | 0 | 3 |
| 2011 February | 2 | 0 | 2 |
| 2011 January | 4 | 0 | 4 |
| 2010 December | 13 | 0 | 13 |
Show all
