array:24 [
  "pii" => "S2173574313000063"
  "issn" => "21735743"
  "doi" => "10.1016/j.reumae.2013.01.003"
  "estado" => "S300"
  "fechaPublicacion" => "2013-09-01"
  "aid" => "503"
  "copyright" => "Elsevier España, S.L.. All rights reserved"
  "copyrightAnyo" => "2012"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "sco"
  "cita" => "Reumatol Clin. 2013;9:316-8"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 1158
    "formatos" => array:3 [
      "EPUB" => 63
      "HTML" => 928
      "PDF" => 167
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S1699258X12002483"
      "issn" => "1699258X"
      "doi" => "10.1016/j.reuma.2012.08.001"
      "estado" => "S300"
      "fechaPublicacion" => "2013-09-01"
      "aid" => "503"
      "copyright" => "Elsevier España, S.L."
      "documento" => "article"
      "crossmark" => 0
      "subdocumento" => "sco"
      "cita" => "Reumatol Clin. 2013;9:316-8"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 8836
        "formatos" => array:3 [
          "EPUB" => 163
          "HTML" => 6903
          "PDF" => 1770
        ]
      ]
      "es" => array:13 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Caso cl&#237;nico</span>"
        "titulo" => "Displasia progresiva seudorreumatoide&#46; Desorden gen&#233;tico raro que simula artritis idiop&#225;tica juvenil"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "316"
            "paginaFinal" => "318"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Pseudorheumatoid dysplasia&#46; A rare genetic disorder simulating juvenile idiopathic arthritis"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0015"
            "etiqueta" => "Figura 3"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr3.jpeg"
                "Alto" => 1021
                "Ancho" => 1300
                "Tamanyo" => 145375
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">a y b&#41; Cuerpos vertebrales tor&#225;cicos y lumbares aplanados&#44; con irregularidades en mesetas vertebrales &#40;platispondilia&#41;&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Carolina Duarte-Salazar, Concepci&#243;n Guadalupe Santill&#225;n-Chapa, Elisa Mart&#237;nez-Coria, Norma Marin-Arriaga, Antonio Miranda-Duarte"
            "autores" => array:5 [
              0 => array:2 [
                "nombre" => "Carolina"
                "apellidos" => "Duarte-Salazar"
              ]
              1 => array:2 [
                "nombre" => "Concepci&#243;n Guadalupe"
                "apellidos" => "Santill&#225;n-Chapa"
              ]
              2 => array:2 [
                "nombre" => "Elisa"
                "apellidos" => "Mart&#237;nez-Coria"
              ]
              3 => array:2 [
                "nombre" => "Norma"
                "apellidos" => "Marin-Arriaga"
              ]
              4 => array:2 [
                "nombre" => "Antonio"
                "apellidos" => "Miranda-Duarte"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2173574313000063"
          "doi" => "10.1016/j.reumae.2013.01.003"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => false
            "ES2" => false
            "LATM" => false
          ]
          "gratuito" => false
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574313000063?idApp=UINPBA00004M"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X12002483?idApp=UINPBA00004M"
      "url" => "/1699258X/0000000900000005/v1_201308061043/S1699258X12002483/v1_201308061043/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2173574313000713"
    "issn" => "21735743"
    "doi" => "10.1016/j.reumae.2012.09.005"
    "estado" => "S300"
    "fechaPublicacion" => "2013-09-01"
    "aid" => "518"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "sco"
    "cita" => "Reumatol Clin. 2013;9:319-21"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 3150
      "formatos" => array:3 [
        "EPUB" => 52
        "HTML" => 2898
        "PDF" => 200
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case Report</span>"
      "titulo" => "What Meralgia Paresthetica can Hide&#58; Renal Tumor as an Infrequent Cause"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "319"
          "paginaFinal" => "321"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Lo que puede esconder una meralgia parest&#233;sica&#58; tumor renal como causa infrecuente"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 777
              "Ancho" => 900
              "Tamanyo" => 125371
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">CT scan where a 79<span class="elsevierStyleHsp" style=""></span>mm mass is seen in the upper pole of the left kidney&#44; with a necrotic center and possible sources of perirenal fat invasion at the top corner&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Marco Aurelio Ram&#237;rez Huaranga, Andr&#233;s Ariza Hern&#225;ndez, Claudia Carolina Ramos Rodr&#237;guez, Jes&#250;s Gonz&#225;lez Garc&#237;a"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Marco Aurelio"
              "apellidos" => "Ram&#237;rez Huaranga"
            ]
            1 => array:2 [
              "nombre" => "Andr&#233;s"
              "apellidos" => "Ariza Hern&#225;ndez"
            ]
            2 => array:2 [
              "nombre" => "Claudia Carolina"
              "apellidos" => "Ramos Rodr&#237;guez"
            ]
            3 => array:2 [
              "nombre" => "Jes&#250;s"
              "apellidos" => "Gonz&#225;lez Garc&#237;a"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S1699258X13000041"
        "doi" => "10.1016/j.reuma.2012.09.007"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X13000041?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574313000713?idApp=UINPBA00004M"
    "url" => "/21735743/0000000900000005/v2_201403300049/S2173574313000713/v2_201403300049/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173574313000920"
    "issn" => "21735743"
    "doi" => "10.1016/j.reumae.2013.02.004"
    "estado" => "S300"
    "fechaPublicacion" => "2013-09-01"
    "aid" => "558"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "ssu"
    "cita" => "Reumatol Clin. 2013;9:303-15"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 3829
      "formatos" => array:3 [
        "EPUB" => 50
        "HTML" => 3316
        "PDF" => 463
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Review Article</span>"
      "titulo" => "Osteoimmunology&#58; The Study of the Relationship Between the Immune System and Bone Tissue"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "303"
          "paginaFinal" => "315"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Osteoinmunolog&#237;a&#58; el estudio de la relaci&#243;n entre el sistema inmune y el tejido &#243;seo"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Fig&#46; 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 1588
              "Ancho" => 3197
              "Tamanyo" => 292177
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Molecular signals with a key role in osteoblast differentiation and activation&#46; MyoD&#58; myogenic differentiation 1 protein&#59; PPAR&#947;&#58; peroxisome proliferator-activated receptor gamma&#59; Sox9&#58; sex determining region Y-box 9&#46; Rest of abbreviations&#58; see Term glossary in <a class="elsevierStyleCrossRef" href="#sec0100">Annex 1</a>&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Luis Arboleya, Santos Casta&#241;eda"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "Luis"
              "apellidos" => "Arboleya"
            ]
            1 => array:2 [
              "nombre" => "Santos"
              "apellidos" => "Casta&#241;eda"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S1699258X13000855"
        "doi" => "10.1016/j.reuma.2013.02.008"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X13000855?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574313000920?idApp=UINPBA00004M"
    "url" => "/21735743/0000000900000005/v2_201403300049/S2173574313000920/v2_201403300049/en/main.assets"
  ]
  "en" => array:20 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case Report</span>"
    "titulo" => "Pseudorheumatoid Dysplasia&#46; A Rare Genetic Disorder Simulating Juvenile Idiopathic Arthritis"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "316"
        "paginaFinal" => "318"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Carolina Duarte-Salazar, Concepci&#243;n Guadalupe Santill&#225;n-Chapa, Elisa Mart&#237;nez-Coria, Norma Marin-Arriaga, Antonio Miranda-Duarte"
        "autores" => array:5 [
          0 => array:4 [
            "nombre" => "Carolina"
            "apellidos" => "Duarte-Salazar"
            "email" => array:1 [
              0 => "cduartes&#64;prodigy&#46;net&#46;mx"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Concepci&#243;n Guadalupe"
            "apellidos" => "Santill&#225;n-Chapa"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Elisa"
            "apellidos" => "Mart&#237;nez-Coria"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Norma"
            "apellidos" => "Marin-Arriaga"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">d</span>"
                "identificador" => "aff0020"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "Antonio"
            "apellidos" => "Miranda-Duarte"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">e</span>"
                "identificador" => "aff0025"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:5 [
          0 => array:3 [
            "entidad" => "Servicio de Reumatolog&#237;a&#44; Instituto Nacional de Rehabilitaci&#243;n&#44; Mexico City&#44; Mexico"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Rehabilitaci&#243;n Pedi&#225;trica&#44; Instituto Nacional de Rehabilitaci&#243;n&#44; Mexico City&#44; Mexico"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Servicio de Tomograf&#237;a Axial Computarizada&#44; Instituto Nacional de Rehabilitaci&#243;n&#44; Mexico City&#44; Mexico"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
          3 => array:3 [
            "entidad" => "Servicio de Radiolog&#237;a&#44; Instituto Nacional de Rehabilitaci&#243;n&#44; Mexico City&#44; Mexico"
            "etiqueta" => "d"
            "identificador" => "aff0020"
          ]
          4 => array:3 [
            "entidad" => "Servicio de Gen&#233;tica&#44; Instituto Nacional de Rehabilitaci&#243;n&#44; Mexico City&#44; Mexico"
            "etiqueta" => "e"
            "identificador" => "aff0025"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Displasia progresiva seudorreumatoide&#46; Desorden gen&#233;tico raro que simula artritis idiop&#225;tica juvenil"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Fig&#46; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 1019
            "Ancho" => 1297
            "Tamanyo" => 144472
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">&#40;a and b&#41; Flattened thoracic and lumbar vertebral bodies with irregularities of their surfaces &#40;platyspondylia&#41;&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Pseudorheumatoid progressive dysplasia &#40;PRPD&#41; is a hereditary&#44; non-inflammatory skeletal disorder&#44; autosomal&#44; and recessive&#44; associated to the WISP3&#46; It is characterized by joint pain and effusion and progressively involves the hips&#44; knees&#44; wrists&#44; and fingers&#46; A reduction in joint mobility and multiple contractures lead to severe disability&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Case Report</span><p id="par0010" class="elsevierStylePara elsevierViewall">A 13-year-old male patient presented pain of the right hip and left knee which had started when he was 13&#46; Five months later he presented swelling of both knees and the interphalangeal joints of the right hand&#46; The patient referred a history of difficulty walking since he was 3 years of age&#46; Upon examination we found a normal teenager with abnormal gait&#44; spinal scoliosis&#44; and kyphosis of the thoracic spine&#46; Mobility of the lumbar spine&#44; coxofemoral joints&#44; knees&#44; ankles&#44; and interphalangeal joints were severely limited&#46; X-rays of the hands and feet &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>a and b&#41;&#44; hips and knees &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>a and b&#41; revealed diffuse osteopenia&#44; tubular widening of the epiphysis and loss of joint space&#44; without erosive lesions&#59; X-rays of the hip and knees also showed degenerative changes&#44; with widening of the femoral heads&#46; Thoracic and lumbar vertebrae were flattened and had an irregular surface &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>a and b&#41;&#46; C reactive protein and erythrosedimentation rate were normal&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Discussion</span><p id="par0015" class="elsevierStylePara elsevierViewall">PRPD clinically simulates early stages of JIA<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;2</span></a>&#59; however&#44; the evidence used to establish the diagnosis of bone dysplasia is non-inflammatory joint involvement and characteristic radiological findings&#44; such as the presence of enlarged epiphyses&#44; generalized osteoporosis&#44; and platyspondylia&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">This disease is caused by mutations in the WISP 3 gene&#44; essential for normal growth and postnatal skeletal and joint cartilage homeostasis&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> Therefore&#44; in contrast to most of the skeletal dysplasias&#44; prenatal skeletal growth and morphogenesis not altered in PRPD and affected individuals are asymptomatic during the first year of life&#46; Subsequently&#44; patients have progressive loss of joint cartilage and severe degenerative changes&#46;<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4&#44;5</span></a></p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Ethical Responsibilities</span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Protection of Persons and Animals</span><p id="par0025" class="elsevierStylePara elsevierViewall">No experiments were performed on humans or animals&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Data Confidentiality</span><p id="par0030" class="elsevierStylePara elsevierViewall">No patient data appear in this article&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Right to Privacy and Informed Consent</span><p id="par0035" class="elsevierStylePara elsevierViewall">No patient data appear in this article&#46;</p></span></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Conflicts of Interest</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to make&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:10 [
        0 => array:2 [
          "identificador" => "xres326512"
          "titulo" => "Abstract"
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec308017"
          "titulo" => "Keywords"
        ]
        2 => array:2 [
          "identificador" => "xres326511"
          "titulo" => "Resumen"
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec308016"
          "titulo" => "Palabras clave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Case Report"
        ]
        6 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Discussion"
        ]
        7 => array:3 [
          "identificador" => "sec0020"
          "titulo" => "Ethical Responsibilities"
          "secciones" => array:3 [
            0 => array:2 [
              "identificador" => "sec0025"
              "titulo" => "Protection of Persons and Animals"
            ]
            1 => array:2 [
              "identificador" => "sec0030"
              "titulo" => "Data Confidentiality"
            ]
            2 => array:2 [
              "identificador" => "sec0035"
              "titulo" => "Right to Privacy and Informed Consent"
            ]
          ]
        ]
        8 => array:2 [
          "identificador" => "sec0040"
          "titulo" => "Conflicts of Interest"
        ]
        9 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2012-04-16"
    "fechaAceptado" => "2012-08-01"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec308017"
          "palabras" => array:3 [
            0 => "Progressive pseudorheumatoid dysplasia"
            1 => "Juvenile idiopathic arthritis"
            2 => "Platyspondylia"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec308016"
          "palabras" => array:3 [
            0 => "Displasia progresiva seudorreumatoide"
            1 => "Artritis idiop&#225;tica juvenil"
            2 => "Platispondilia"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">We present the case of a teenage patient with progressive pseudorheumatoid dysplasia&#44; an autosomal recessive disorder that may be initially misdiagnosed as juvenile idiopathic arthritis&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Adolescente con displasia progresiva seudorreumatoide&#44; desorden autos&#243;mico recesivo que puede ser diagnosticado inicialmente como artritis idiop&#225;tica juvenil&#46;</p>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara">Please&#44; cite this article as&#58; Duarte-Salazar C&#44; et al&#46; Displasia progresiva seudorreumatoide&#46; Desorden gen&#233;tico raro que simula artritis idiop&#225;tica juvenil&#46; Reumatol Clin&#46; 2013&#59;9&#58;316&#8211;321&#46;</p>"
      ]
    ]
    "multimedia" => array:3 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 505
            "Ancho" => 1298
            "Tamanyo" => 73209
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">&#40;a and b&#41; Hand and feet X-rays show osteopenia&#44; tubular epiphyseal widening and loss of joint space&#44; without erosions&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 482
            "Ancho" => 1299
            "Tamanyo" => 75188
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">&#40;a and b&#41; Coxofemoral and knee X-rays show severe degenerative changes&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Fig&#46; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 1019
            "Ancho" => 1297
            "Tamanyo" => 144472
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">&#40;a and b&#41; Flattened thoracic and lumbar vertebral bodies with irregularities of their surfaces &#40;platyspondylia&#41;&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An eleven year old female Turkish patient with progressive pseudorheumatoid displasia mimicking juvenile idiopathic arthritis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "S&#46; Balci"
                            1 => "E&#46; Aypar"
                            2 => "O&#46; Kasapcopur"
                            3 => "B&#46; T&#252;ys&#252;z"
                            4 => "N&#46; Arisoy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Clin Exp Rheumatol"
                        "fecha" => "2001"
                        "volumen" => "19"
                        "paginaInicial" => "759"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11791657"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical and radiological diagnosis of progressive pseudorheumatoid dysplasia in two sisters with severe polyarthropathy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46; Kaya"
                            1 => "S&#46; Ozogocmen"
                            2 => "A&#46; Kiris"
                            3 => "I&#46; Ciftci"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Clin Rheumatol"
                        "fecha" => "2005"
                        "volumen" => "24"
                        "paginaInicial" => "660"
                        "paginaFinal" => "664"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical&#44; radiographic&#44; and genetic diagnosis of progressive pseudorheumatoid dysplasia in a patient with severe polyarthropathy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "S&#46; Ehl"
                            1 => "M&#46; Uhl"
                            2 => "R&#46; Berner"
                            3 => "L&#46; Bonafe"
                            4 => "A&#46; Superti-Furga"
                            5 => "A&#46; Kirchhoff"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00296-003-0341-0"
                      "Revista" => array:6 [
                        "tituloSerie" => "Rheumatol Int"
                        "fecha" => "2004"
                        "volumen" => "24"
                        "paginaInicial" => "53"
                        "paginaFinal" => "56"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12819927"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mutations in the CCN gene family members WISP3 cause progressive pseudorheumatoid dysplasia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46;R&#46; Hurvitz"
                            1 => "W&#46;M&#46; Suwairi"
                            2 => "W&#46; Van Hul"
                            3 => "H&#46; El-Shanti"
                            4 => "A&#46; Superti-Furga"
                            5 => "J&#46; Roudier"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1038/12699"
                      "Revista" => array:6 [
                        "tituloSerie" => "Nat Genet"
                        "fecha" => "1999"
                        "volumen" => "23"
                        "paginaInicial" => "94"
                        "paginaFinal" => "98"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10471507"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Patients with progressive pseudo-rheumatoid dysplasia&#58; from clinical diagnosis to molecular studies"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46; Ye"
                            1 => "H&#46;W&#46; Zhang"
                            2 => "W&#46;J&#46; Qiu"
                            3 => "L&#46;S&#46; Han"
                            4 => "Y&#46;F&#46; Zhang"
                            5 => "Z&#46;W&#46; Gong"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3892/mmr.2011.619"
                      "Revista" => array:6 [
                        "tituloSerie" => "Mol Med Rep"
                        "fecha" => "2012"
                        "volumen" => "5"
                        "paginaInicial" => "190"
                        "paginaFinal" => "195"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21993478"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735743/0000000900000005/v2_201403300049/S2173574313000063/v2_201403300049/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "17376"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Case Report"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735743/0000000900000005/v2_201403300049/S2173574313000063/v2_201403300049/en/main.pdf?idApp=UINPBA00004M&text.app=https://reumatologiaclinica.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574313000063?idApp=UINPBA00004M"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Case Report
Pseudorheumatoid Dysplasia. A Rare Genetic Disorder Simulating Juvenile Idiopathic Arthritis
Displasia progresiva seudorreumatoide. Desorden genético raro que simula artritis idiopática juvenil
Carolina Duarte-Salazara,
Corresponding author
cduartes@prodigy.net.mx

Corresponding author.
, Concepción Guadalupe Santillán-Chapab, Elisa Martínez-Coriac, Norma Marin-Arriagad, Antonio Miranda-Duartee
a Servicio de Reumatología, Instituto Nacional de Rehabilitación, Mexico City, Mexico
b Servicio de Rehabilitación Pediátrica, Instituto Nacional de Rehabilitación, Mexico City, Mexico
c Servicio de Tomografía Axial Computarizada, Instituto Nacional de Rehabilitación, Mexico City, Mexico
d Servicio de Radiología, Instituto Nacional de Rehabilitación, Mexico City, Mexico
e Servicio de Genética, Instituto Nacional de Rehabilitación, Mexico City, Mexico
Read
6591
Times
was read the article
2002
Total PDF
4589
Total HTML
Share statistics
 array:24 [
  "pii" => "S2173574313000063"
  "issn" => "21735743"
  "doi" => "10.1016/j.reumae.2013.01.003"
  "estado" => "S300"
  "fechaPublicacion" => "2013-09-01"
  "aid" => "503"
  "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;. All rights reserved"
  "copyrightAnyo" => "2012"
  "documento" => "article"
  "crossmark" => 0
  "subdocumento" => "sco"
  "cita" => "Reumatol Clin. 2013;9:316-8"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 1158
    "formatos" => array:3 [
      "EPUB" => 63
      "HTML" => 928
      "PDF" => 167
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S1699258X12002483"
      "issn" => "1699258X"
      "doi" => "10.1016/j.reuma.2012.08.001"
      "estado" => "S300"
      "fechaPublicacion" => "2013-09-01"
      "aid" => "503"
      "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;"
      "documento" => "article"
      "crossmark" => 0
      "subdocumento" => "sco"
      "cita" => "Reumatol Clin. 2013;9:316-8"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 8836
        "formatos" => array:3 [
          "EPUB" => 163
          "HTML" => 6903
          "PDF" => 1770
        ]
      ]
      "es" => array:13 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Caso cl&#237;nico</span>"
        "titulo" => "Displasia progresiva seudorreumatoide&#46; Desorden gen&#233;tico raro que simula artritis idiop&#225;tica juvenil"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "316"
            "paginaFinal" => "318"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Pseudorheumatoid dysplasia&#46; A rare genetic disorder simulating juvenile idiopathic arthritis"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0015"
            "etiqueta" => "Figura 3"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr3.jpeg"
                "Alto" => 1021
                "Ancho" => 1300
                "Tamanyo" => 145375
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">a y b&#41; Cuerpos vertebrales tor&#225;cicos y lumbares aplanados&#44; con irregularidades en mesetas vertebrales &#40;platispondilia&#41;&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Carolina Duarte-Salazar, Concepci&#243;n Guadalupe Santill&#225;n-Chapa, Elisa Mart&#237;nez-Coria, Norma Marin-Arriaga, Antonio Miranda-Duarte"
            "autores" => array:5 [
              0 => array:2 [
                "nombre" => "Carolina"
                "apellidos" => "Duarte-Salazar"
              ]
              1 => array:2 [
                "nombre" => "Concepci&#243;n Guadalupe"
                "apellidos" => "Santill&#225;n-Chapa"
              ]
              2 => array:2 [
                "nombre" => "Elisa"
                "apellidos" => "Mart&#237;nez-Coria"
              ]
              3 => array:2 [
                "nombre" => "Norma"
                "apellidos" => "Marin-Arriaga"
              ]
              4 => array:2 [
                "nombre" => "Antonio"
                "apellidos" => "Miranda-Duarte"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2173574313000063"
          "doi" => "10.1016/j.reumae.2013.01.003"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => false
            "ES2" => false
            "LATM" => false
          ]
          "gratuito" => false
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574313000063?idApp=UINPBA00004M"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X12002483?idApp=UINPBA00004M"
      "url" => "/1699258X/0000000900000005/v1_201308061043/S1699258X12002483/v1_201308061043/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2173574313000713"
    "issn" => "21735743"
    "doi" => "10.1016/j.reumae.2012.09.005"
    "estado" => "S300"
    "fechaPublicacion" => "2013-09-01"
    "aid" => "518"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "sco"
    "cita" => "Reumatol Clin. 2013;9:319-21"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 3150
      "formatos" => array:3 [
        "EPUB" => 52
        "HTML" => 2898
        "PDF" => 200
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case Report</span>"
      "titulo" => "What Meralgia Paresthetica can Hide&#58; Renal Tumor as an Infrequent Cause"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "319"
          "paginaFinal" => "321"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Lo que puede esconder una meralgia parest&#233;sica&#58; tumor renal como causa infrecuente"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 777
              "Ancho" => 900
              "Tamanyo" => 125371
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">CT scan where a 79<span class="elsevierStyleHsp" style=""></span>mm mass is seen in the upper pole of the left kidney&#44; with a necrotic center and possible sources of perirenal fat invasion at the top corner&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Marco Aurelio Ram&#237;rez Huaranga, Andr&#233;s Ariza Hern&#225;ndez, Claudia Carolina Ramos Rodr&#237;guez, Jes&#250;s Gonz&#225;lez Garc&#237;a"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Marco Aurelio"
              "apellidos" => "Ram&#237;rez Huaranga"
            ]
            1 => array:2 [
              "nombre" => "Andr&#233;s"
              "apellidos" => "Ariza Hern&#225;ndez"
            ]
            2 => array:2 [
              "nombre" => "Claudia Carolina"
              "apellidos" => "Ramos Rodr&#237;guez"
            ]
            3 => array:2 [
              "nombre" => "Jes&#250;s"
              "apellidos" => "Gonz&#225;lez Garc&#237;a"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S1699258X13000041"
        "doi" => "10.1016/j.reuma.2012.09.007"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X13000041?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574313000713?idApp=UINPBA00004M"
    "url" => "/21735743/0000000900000005/v2_201403300049/S2173574313000713/v2_201403300049/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173574313000920"
    "issn" => "21735743"
    "doi" => "10.1016/j.reumae.2013.02.004"
    "estado" => "S300"
    "fechaPublicacion" => "2013-09-01"
    "aid" => "558"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;"
    "documento" => "article"
    "crossmark" => 0
    "subdocumento" => "ssu"
    "cita" => "Reumatol Clin. 2013;9:303-15"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 3829
      "formatos" => array:3 [
        "EPUB" => 50
        "HTML" => 3316
        "PDF" => 463
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Review Article</span>"
      "titulo" => "Osteoimmunology&#58; The Study of the Relationship Between the Immune System and Bone Tissue"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "303"
          "paginaFinal" => "315"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Osteoinmunolog&#237;a&#58; el estudio de la relaci&#243;n entre el sistema inmune y el tejido &#243;seo"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Fig&#46; 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 1588
              "Ancho" => 3197
              "Tamanyo" => 292177
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Molecular signals with a key role in osteoblast differentiation and activation&#46; MyoD&#58; myogenic differentiation 1 protein&#59; PPAR&#947;&#58; peroxisome proliferator-activated receptor gamma&#59; Sox9&#58; sex determining region Y-box 9&#46; Rest of abbreviations&#58; see Term glossary in <a class="elsevierStyleCrossRef" href="#sec0100">Annex 1</a>&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Luis Arboleya, Santos Casta&#241;eda"
          "autores" => array:2 [
            0 => array:2 [
              "nombre" => "Luis"
              "apellidos" => "Arboleya"
            ]
            1 => array:2 [
              "nombre" => "Santos"
              "apellidos" => "Casta&#241;eda"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S1699258X13000855"
        "doi" => "10.1016/j.reuma.2013.02.008"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X13000855?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574313000920?idApp=UINPBA00004M"
    "url" => "/21735743/0000000900000005/v2_201403300049/S2173574313000920/v2_201403300049/en/main.assets"
  ]
  "en" => array:20 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case Report</span>"
    "titulo" => "Pseudorheumatoid Dysplasia&#46; A Rare Genetic Disorder Simulating Juvenile Idiopathic Arthritis"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "316"
        "paginaFinal" => "318"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Carolina Duarte-Salazar, Concepci&#243;n Guadalupe Santill&#225;n-Chapa, Elisa Mart&#237;nez-Coria, Norma Marin-Arriaga, Antonio Miranda-Duarte"
        "autores" => array:5 [
          0 => array:4 [
            "nombre" => "Carolina"
            "apellidos" => "Duarte-Salazar"
            "email" => array:1 [
              0 => "cduartes&#64;prodigy&#46;net&#46;mx"
            ]
            "referencia" => array:2 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">a</span>"
                "identificador" => "aff0005"
              ]
              1 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">¿</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:3 [
            "nombre" => "Concepci&#243;n Guadalupe"
            "apellidos" => "Santill&#225;n-Chapa"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">b</span>"
                "identificador" => "aff0010"
              ]
            ]
          ]
          2 => array:3 [
            "nombre" => "Elisa"
            "apellidos" => "Mart&#237;nez-Coria"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">c</span>"
                "identificador" => "aff0015"
              ]
            ]
          ]
          3 => array:3 [
            "nombre" => "Norma"
            "apellidos" => "Marin-Arriaga"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">d</span>"
                "identificador" => "aff0020"
              ]
            ]
          ]
          4 => array:3 [
            "nombre" => "Antonio"
            "apellidos" => "Miranda-Duarte"
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">e</span>"
                "identificador" => "aff0025"
              ]
            ]
          ]
        ]
        "afiliaciones" => array:5 [
          0 => array:3 [
            "entidad" => "Servicio de Reumatolog&#237;a&#44; Instituto Nacional de Rehabilitaci&#243;n&#44; Mexico City&#44; Mexico"
            "etiqueta" => "a"
            "identificador" => "aff0005"
          ]
          1 => array:3 [
            "entidad" => "Servicio de Rehabilitaci&#243;n Pedi&#225;trica&#44; Instituto Nacional de Rehabilitaci&#243;n&#44; Mexico City&#44; Mexico"
            "etiqueta" => "b"
            "identificador" => "aff0010"
          ]
          2 => array:3 [
            "entidad" => "Servicio de Tomograf&#237;a Axial Computarizada&#44; Instituto Nacional de Rehabilitaci&#243;n&#44; Mexico City&#44; Mexico"
            "etiqueta" => "c"
            "identificador" => "aff0015"
          ]
          3 => array:3 [
            "entidad" => "Servicio de Radiolog&#237;a&#44; Instituto Nacional de Rehabilitaci&#243;n&#44; Mexico City&#44; Mexico"
            "etiqueta" => "d"
            "identificador" => "aff0020"
          ]
          4 => array:3 [
            "entidad" => "Servicio de Gen&#233;tica&#44; Instituto Nacional de Rehabilitaci&#243;n&#44; Mexico City&#44; Mexico"
            "etiqueta" => "e"
            "identificador" => "aff0025"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Displasia progresiva seudorreumatoide&#46; Desorden gen&#233;tico raro que simula artritis idiop&#225;tica juvenil"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Fig&#46; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 1019
            "Ancho" => 1297
            "Tamanyo" => 144472
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">&#40;a and b&#41; Flattened thoracic and lumbar vertebral bodies with irregularities of their surfaces &#40;platyspondylia&#41;&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Pseudorheumatoid progressive dysplasia &#40;PRPD&#41; is a hereditary&#44; non-inflammatory skeletal disorder&#44; autosomal&#44; and recessive&#44; associated to the WISP3&#46; It is characterized by joint pain and effusion and progressively involves the hips&#44; knees&#44; wrists&#44; and fingers&#46; A reduction in joint mobility and multiple contractures lead to severe disability&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Case Report</span><p id="par0010" class="elsevierStylePara elsevierViewall">A 13-year-old male patient presented pain of the right hip and left knee which had started when he was 13&#46; Five months later he presented swelling of both knees and the interphalangeal joints of the right hand&#46; The patient referred a history of difficulty walking since he was 3 years of age&#46; Upon examination we found a normal teenager with abnormal gait&#44; spinal scoliosis&#44; and kyphosis of the thoracic spine&#46; Mobility of the lumbar spine&#44; coxofemoral joints&#44; knees&#44; ankles&#44; and interphalangeal joints were severely limited&#46; X-rays of the hands and feet &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>a and b&#41;&#44; hips and knees &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>a and b&#41; revealed diffuse osteopenia&#44; tubular widening of the epiphysis and loss of joint space&#44; without erosive lesions&#59; X-rays of the hip and knees also showed degenerative changes&#44; with widening of the femoral heads&#46; Thoracic and lumbar vertebrae were flattened and had an irregular surface &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>a and b&#41;&#46; C reactive protein and erythrosedimentation rate were normal&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Discussion</span><p id="par0015" class="elsevierStylePara elsevierViewall">PRPD clinically simulates early stages of JIA<a class="elsevierStyleCrossRefs" href="#bib0005"><span class="elsevierStyleSup">1&#44;2</span></a>&#59; however&#44; the evidence used to establish the diagnosis of bone dysplasia is non-inflammatory joint involvement and characteristic radiological findings&#44; such as the presence of enlarged epiphyses&#44; generalized osteoporosis&#44; and platyspondylia&#46;<a class="elsevierStyleCrossRef" href="#bib0015"><span class="elsevierStyleSup">3</span></a></p><p id="par0020" class="elsevierStylePara elsevierViewall">This disease is caused by mutations in the WISP 3 gene&#44; essential for normal growth and postnatal skeletal and joint cartilage homeostasis&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">4</span></a> Therefore&#44; in contrast to most of the skeletal dysplasias&#44; prenatal skeletal growth and morphogenesis not altered in PRPD and affected individuals are asymptomatic during the first year of life&#46; Subsequently&#44; patients have progressive loss of joint cartilage and severe degenerative changes&#46;<a class="elsevierStyleCrossRefs" href="#bib0020"><span class="elsevierStyleSup">4&#44;5</span></a></p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Ethical Responsibilities</span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Protection of Persons and Animals</span><p id="par0025" class="elsevierStylePara elsevierViewall">No experiments were performed on humans or animals&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Data Confidentiality</span><p id="par0030" class="elsevierStylePara elsevierViewall">No patient data appear in this article&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Right to Privacy and Informed Consent</span><p id="par0035" class="elsevierStylePara elsevierViewall">No patient data appear in this article&#46;</p></span></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle">Conflicts of Interest</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors have no conflicts of interest to make&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:10 [
        0 => array:2 [
          "identificador" => "xres326512"
          "titulo" => "Abstract"
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec308017"
          "titulo" => "Keywords"
        ]
        2 => array:2 [
          "identificador" => "xres326511"
          "titulo" => "Resumen"
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec308016"
          "titulo" => "Palabras clave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Case Report"
        ]
        6 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Discussion"
        ]
        7 => array:3 [
          "identificador" => "sec0020"
          "titulo" => "Ethical Responsibilities"
          "secciones" => array:3 [
            0 => array:2 [
              "identificador" => "sec0025"
              "titulo" => "Protection of Persons and Animals"
            ]
            1 => array:2 [
              "identificador" => "sec0030"
              "titulo" => "Data Confidentiality"
            ]
            2 => array:2 [
              "identificador" => "sec0035"
              "titulo" => "Right to Privacy and Informed Consent"
            ]
          ]
        ]
        8 => array:2 [
          "identificador" => "sec0040"
          "titulo" => "Conflicts of Interest"
        ]
        9 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2012-04-16"
    "fechaAceptado" => "2012-08-01"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec308017"
          "palabras" => array:3 [
            0 => "Progressive pseudorheumatoid dysplasia"
            1 => "Juvenile idiopathic arthritis"
            2 => "Platyspondylia"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec308016"
          "palabras" => array:3 [
            0 => "Displasia progresiva seudorreumatoide"
            1 => "Artritis idiop&#225;tica juvenil"
            2 => "Platispondilia"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">We present the case of a teenage patient with progressive pseudorheumatoid dysplasia&#44; an autosomal recessive disorder that may be initially misdiagnosed as juvenile idiopathic arthritis&#46;</p>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Adolescente con displasia progresiva seudorreumatoide&#44; desorden autos&#243;mico recesivo que puede ser diagnosticado inicialmente como artritis idiop&#225;tica juvenil&#46;</p>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara">Please&#44; cite this article as&#58; Duarte-Salazar C&#44; et al&#46; Displasia progresiva seudorreumatoide&#46; Desorden gen&#233;tico raro que simula artritis idiop&#225;tica juvenil&#46; Reumatol Clin&#46; 2013&#59;9&#58;316&#8211;321&#46;</p>"
      ]
    ]
    "multimedia" => array:3 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 505
            "Ancho" => 1298
            "Tamanyo" => 73209
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">&#40;a and b&#41; Hand and feet X-rays show osteopenia&#44; tubular epiphyseal widening and loss of joint space&#44; without erosions&#46;</p>"
        ]
      ]
      1 => array:7 [
        "identificador" => "fig0010"
        "etiqueta" => "Fig&#46; 2"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr2.jpeg"
            "Alto" => 482
            "Ancho" => 1299
            "Tamanyo" => 75188
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">&#40;a and b&#41; Coxofemoral and knee X-rays show severe degenerative changes&#46;</p>"
        ]
      ]
      2 => array:7 [
        "identificador" => "fig0015"
        "etiqueta" => "Fig&#46; 3"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr3.jpeg"
            "Alto" => 1019
            "Ancho" => 1297
            "Tamanyo" => 144472
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0025" class="elsevierStyleSimplePara elsevierViewall">&#40;a and b&#41; Flattened thoracic and lumbar vertebral bodies with irregularities of their surfaces &#40;platyspondylia&#41;&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0005"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "An eleven year old female Turkish patient with progressive pseudorheumatoid displasia mimicking juvenile idiopathic arthritis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "S&#46; Balci"
                            1 => "E&#46; Aypar"
                            2 => "O&#46; Kasapcopur"
                            3 => "B&#46; T&#252;ys&#252;z"
                            4 => "N&#46; Arisoy"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Clin Exp Rheumatol"
                        "fecha" => "2001"
                        "volumen" => "19"
                        "paginaInicial" => "759"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/11791657"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0010"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical and radiological diagnosis of progressive pseudorheumatoid dysplasia in two sisters with severe polyarthropathy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "A&#46; Kaya"
                            1 => "S&#46; Ozogocmen"
                            2 => "A&#46; Kiris"
                            3 => "I&#46; Ciftci"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Clin Rheumatol"
                        "fecha" => "2005"
                        "volumen" => "24"
                        "paginaInicial" => "660"
                        "paginaFinal" => "664"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0015"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical&#44; radiographic&#44; and genetic diagnosis of progressive pseudorheumatoid dysplasia in a patient with severe polyarthropathy"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "S&#46; Ehl"
                            1 => "M&#46; Uhl"
                            2 => "R&#46; Berner"
                            3 => "L&#46; Bonafe"
                            4 => "A&#46; Superti-Furga"
                            5 => "A&#46; Kirchhoff"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s00296-003-0341-0"
                      "Revista" => array:6 [
                        "tituloSerie" => "Rheumatol Int"
                        "fecha" => "2004"
                        "volumen" => "24"
                        "paginaInicial" => "53"
                        "paginaFinal" => "56"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/12819927"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0020"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mutations in the CCN gene family members WISP3 cause progressive pseudorheumatoid dysplasia"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
                            0 => "J&#46;R&#46; Hurvitz"
                            1 => "W&#46;M&#46; Suwairi"
                            2 => "W&#46; Van Hul"
                            3 => "H&#46; El-Shanti"
                            4 => "A&#46; Superti-Furga"
                            5 => "J&#46; Roudier"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1038/12699"
                      "Revista" => array:6 [
                        "tituloSerie" => "Nat Genet"
                        "fecha" => "1999"
                        "volumen" => "23"
                        "paginaInicial" => "94"
                        "paginaFinal" => "98"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/10471507"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0025"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Patients with progressive pseudo-rheumatoid dysplasia&#58; from clinical diagnosis to molecular studies"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "J&#46; Ye"
                            1 => "H&#46;W&#46; Zhang"
                            2 => "W&#46;J&#46; Qiu"
                            3 => "L&#46;S&#46; Han"
                            4 => "Y&#46;F&#46; Zhang"
                            5 => "Z&#46;W&#46; Gong"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.3892/mmr.2011.619"
                      "Revista" => array:6 [
                        "tituloSerie" => "Mol Med Rep"
                        "fecha" => "2012"
                        "volumen" => "5"
                        "paginaInicial" => "190"
                        "paginaFinal" => "195"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21993478"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735743/0000000900000005/v2_201403300049/S2173574313000063/v2_201403300049/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "17376"
    "tipo" => "SECCION"
    "es" => array:2 [
      "titulo" => "Case Report"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "es"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735743/0000000900000005/v2_201403300049/S2173574313000063/v2_201403300049/en/main.pdf?idApp=UINPBA00004M&text.app=https://reumatologiaclinica.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574313000063?idApp=UINPBA00004M"
]
Article information
ISSN: 21735743
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 14 11 25
2024 October 63 37 100
2024 September 67 17 84
2024 August 88 29 117
2024 July 59 26 85
2024 June 67 33 100
2024 May 69 28 97
2024 April 68 33 101
2024 March 93 37 130
2024 February 46 33 79
2024 January 40 27 67
2023 December 70 38 108
2023 November 62 57 119
2023 October 62 33 95
2023 September 83 41 124
2023 August 41 16 57
2023 July 76 24 100
2023 June 51 23 74
2023 May 72 21 93
2023 April 52 9 61
2023 March 88 27 115
2023 February 64 33 97
2023 January 81 42 123
2022 December 85 31 116
2022 November 90 32 122
2022 October 81 47 128
2022 September 84 31 115
2022 August 93 50 143
2022 July 87 53 140
2022 June 69 36 105
2022 May 96 47 143
2022 April 49 56 105
2022 March 58 58 116
2022 February 70 31 101
2022 January 65 33 98
2021 December 56 45 101
2021 November 88 46 134
2021 October 66 53 119
2021 September 96 46 142
2021 August 88 39 127
2021 July 68 44 112
2021 June 87 36 123
2021 May 62 32 94
2021 April 117 72 189
2021 March 97 18 115
2021 February 53 23 76
2021 January 56 18 74
2020 December 49 21 70
2020 November 44 22 66
2020 October 40 10 50
2020 September 27 34 61
2020 August 25 20 45
2020 July 27 24 51
2020 June 31 22 53
2020 May 36 8 44
2020 April 26 13 39
2020 March 19 9 28
2020 January 1 0 1
2019 November 2 0 2
2019 October 1 0 1
2019 September 2 0 2
2019 July 1 0 1
2019 May 2 0 2
2019 April 2 0 2
2019 March 4 0 4
2019 February 3 0 3
2019 January 5 0 5
2018 December 2 0 2
2018 May 5 0 5
2018 April 81 5 86
2018 March 79 7 86
2018 February 23 4 27
2018 January 21 4 25
2017 December 31 10 41
2017 November 37 7 44
2017 October 32 5 37
2017 September 28 8 36
2017 August 28 10 38
2017 July 22 11 33
2017 June 47 8 55
2017 May 40 10 50
2017 April 34 7 41
2017 March 32 5 37
2017 February 26 6 32
2017 January 34 9 43
2016 December 66 10 76
2016 November 45 9 54
2016 October 53 15 68
2016 September 65 7 72
2016 August 52 5 57
2016 July 22 5 27
Show all

Follow this link to access the full text of the article

Idiomas
Reumatología Clínica (English Edition)
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?