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in left rotator muscles&#44; as well as in the gluteus maximus&#44; where the area of myositis was greater and was accompanied by a small central abscess&#46; Thus&#44; empirical antibiotic therapy with ceftriaxone and cloxacillin was begun&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">When methicillin-sensitive <span class="elsevierStyleItalic">Staphylococcus aureus</span> was isolated from the blood sample collected in the emergency department&#44; ceftriaxone was discontinued&#44; whereas cloxacillin administration was maintained&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Echocardiography revealed no evidence of endocarditis&#46; One month later&#44; follow-up MRI &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41; showed that subchondral bone edema persisted on both the sacral and iliac sides of left sacroiliac joint&#44; indicating the persistence of sacroiliitis&#59; in contrast&#44; the area of myositis and the abscess in gluteus maximus had disappeared&#44; a foreseeable finding&#44; given the short time elapsed since the first MRI&#46; The patient continued to improve&#44; both in clinical and analytical terms&#44; with antibiotic therapy&#44; which was maintained for 6 weeks&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Discussion</span><p id="par0025" class="elsevierStylePara elsevierViewall">Both infectious sacroiliitis and gluteal abscesses are uncommon conditions&#44; representing less than 1&#37; of all the cases of septic arthritis&#46;<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">1&#44;2</span></a> The clinical diagnosis is usually difficult&#44; as the classical signs are fever and pain&#44; with functional incapacity of the affected joint&#46;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">3&#44;4</span></a> In this case&#44; as in the majority of the published series&#44; the causative agent was <span class="elsevierStyleItalic">S&#46; aureus</span>&#46;<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">1&#8211;10</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">The risk factors most frequently identified in the cases of this type of joint infection reported in the literature are&#58; intravenous drug use&#44; pregnancy&#44; trauma&#44; endocarditis&#44; hemoglobinopathies&#44; immunosuppression&#44; and skin&#44; respiratory tract or genitourinary infections&#46;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">5</span></a> According to different series&#44; no predisposing agents or risk factors are identified in 40&#37;&#8211;44&#37; of the cases&#46;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">3&#44;5&#44;6</span></a> In our patient&#44; intraurethral administration of alprostadil is a plausible candidate as the route of infection responsible for the bacteremia&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Abscess management usually involves drainage by needle aspiration or surgery&#46;<a class="elsevierStyleCrossRefs" href="#bib0090"><span class="elsevierStyleSup">8&#8211;10</span></a> However&#44; there have been reports of complete resolution with antibiotic therapy alone&#44;<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">10</span></a> as in the case we present here&#46; To date&#44; there are no established guidelines for the duration of antibiotic therapy&#44; but most authors opt for a minimum of 6 weeks&#44; which can be extended depending on the clinical status of the patient&#46;<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">1&#44;3&#8211;5&#44;7&#8211;10</span></a></p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Ethical Disclosures</span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Protection of human and animal subjects</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors declare that the procedures followed were in accordance with the regulations of the relevant clinical research ethics committee and with those of the Code of Ethics of the World Medical Association &#40;Declaration of Helsinki&#41;&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Confidentiality of data</span><p id="par0045" class="elsevierStylePara elsevierViewall">The authors declare that they have followed the protocols of their work center on the publication of patient data&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Right to privacy and informed consent</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors have obtained the written informed consent of the patients or subjects mentioned in the article&#46; The corresponding author is in possession of this document&#46;</p></span></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Conflicts of Interest</span><p id="par0055" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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Images in Clinical Rheumatology
Sacroiliitis and Gluteal Abscess Secondary to Staphylococcus aureus Infection
Sacroilitis y absceso glúteo secundarios a infección por Staphylococcus aureus
Maria Llop Vilaltella
Corresponding author
mariallop@hotmail.com

Corresponding author.
, Valentina Maldonado Romero, Carlos Guillén Astete, Carlos de la Puente Bujidos, Celia de Casanova Peña
Servicio de Reumatología, Hospital Universitario Ramón y Cajal, Madrid, Spain
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and a procalcitonin level of 1&#46;18<span class="elsevierStyleHsp" style=""></span>ng&#47;ml &#40;&#60;0&#46;25&#41;&#44; without leukocytosis or left shift&#46; Abdominopelvic computed tomography &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41; detected the presence of cortical erosions&#44; predominantly on the lower half of the iliac side of left sacroiliac joint&#44; associated with subchondral sclerosis&#44; all of which is compatible with the radiological diagnosis of left-sided sacroiliitis&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Pelvic magnetic resonance imaging &#40;MRI&#41; &#40;<a class="elsevierStyleCrossRef" href="#fig0010">Fig&#46; 2</a>&#41; revealed subchondral bone edema on both the sacral and iliac sides of left sacroiliac joint&#44; as well as subtle signal hyperintensity in the articular interosseous space&#46; In addition&#44; myositis was observed in neighboring muscles&#44; in left rotator muscles&#44; as well as in the gluteus maximus&#44; where the area of myositis was greater and was accompanied by a small central abscess&#46; Thus&#44; empirical antibiotic therapy with ceftriaxone and cloxacillin was begun&#46;</p><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0015" class="elsevierStylePara elsevierViewall">When methicillin-sensitive <span class="elsevierStyleItalic">Staphylococcus aureus</span> was isolated from the blood sample collected in the emergency department&#44; ceftriaxone was discontinued&#44; whereas cloxacillin administration was maintained&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">Echocardiography revealed no evidence of endocarditis&#46; One month later&#44; follow-up MRI &#40;<a class="elsevierStyleCrossRef" href="#fig0015">Fig&#46; 3</a>&#41; showed that subchondral bone edema persisted on both the sacral and iliac sides of left sacroiliac joint&#44; indicating the persistence of sacroiliitis&#59; in contrast&#44; the area of myositis and the abscess in gluteus maximus had disappeared&#44; a foreseeable finding&#44; given the short time elapsed since the first MRI&#46; The patient continued to improve&#44; both in clinical and analytical terms&#44; with antibiotic therapy&#44; which was maintained for 6 weeks&#46;</p><elsevierMultimedia ident="fig0015"></elsevierMultimedia></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Discussion</span><p id="par0025" class="elsevierStylePara elsevierViewall">Both infectious sacroiliitis and gluteal abscesses are uncommon conditions&#44; representing less than 1&#37; of all the cases of septic arthritis&#46;<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">1&#44;2</span></a> The clinical diagnosis is usually difficult&#44; as the classical signs are fever and pain&#44; with functional incapacity of the affected joint&#46;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">3&#44;4</span></a> In this case&#44; as in the majority of the published series&#44; the causative agent was <span class="elsevierStyleItalic">S&#46; aureus</span>&#46;<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">1&#8211;10</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">The risk factors most frequently identified in the cases of this type of joint infection reported in the literature are&#58; intravenous drug use&#44; pregnancy&#44; trauma&#44; endocarditis&#44; hemoglobinopathies&#44; immunosuppression&#44; and skin&#44; respiratory tract or genitourinary infections&#46;<a class="elsevierStyleCrossRef" href="#bib0075"><span class="elsevierStyleSup">5</span></a> According to different series&#44; no predisposing agents or risk factors are identified in 40&#37;&#8211;44&#37; of the cases&#46;<a class="elsevierStyleCrossRefs" href="#bib0065"><span class="elsevierStyleSup">3&#44;5&#44;6</span></a> In our patient&#44; intraurethral administration of alprostadil is a plausible candidate as the route of infection responsible for the bacteremia&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Abscess management usually involves drainage by needle aspiration or surgery&#46;<a class="elsevierStyleCrossRefs" href="#bib0090"><span class="elsevierStyleSup">8&#8211;10</span></a> However&#44; there have been reports of complete resolution with antibiotic therapy alone&#44;<a class="elsevierStyleCrossRef" href="#bib0100"><span class="elsevierStyleSup">10</span></a> as in the case we present here&#46; To date&#44; there are no established guidelines for the duration of antibiotic therapy&#44; but most authors opt for a minimum of 6 weeks&#44; which can be extended depending on the clinical status of the patient&#46;<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">1&#44;3&#8211;5&#44;7&#8211;10</span></a></p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Ethical Disclosures</span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Protection of human and animal subjects</span><p id="par0040" class="elsevierStylePara elsevierViewall">The authors declare that the procedures followed were in accordance with the regulations of the relevant clinical research ethics committee and with those of the Code of Ethics of the World Medical Association &#40;Declaration of Helsinki&#41;&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Confidentiality of data</span><p id="par0045" class="elsevierStylePara elsevierViewall">The authors declare that they have followed the protocols of their work center on the publication of patient data&#46;</p></span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Right to privacy and informed consent</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors have obtained the written informed consent of the patients or subjects mentioned in the article&#46; The corresponding author is in possession of this document&#46;</p></span></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Conflicts of Interest</span><p id="par0055" class="elsevierStylePara elsevierViewall">The authors declare that they have no conflicts of interest&#46;</p></span></span>"
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Idiomas
Reumatología Clínica (English Edition)
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