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The cytopathology of this tissue shows active hemophagocytosis on the part of macrophages (hematoxylin-eosin staining, 1000×).</p>" ] ] ] "autores" => array:1 [ 0 => array:2 [ "autoresLista" => "Leslye F. Conde, Karla P. Aedo, Tatiana Miraval-Niño de Guzmán" "autores" => array:3 [ 0 => array:2 [ "nombre" => "Leslye F." "apellidos" => "Conde" ] 1 => array:2 [ "nombre" => "Karla P." 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Computed tomography of sacroiliac joints showing axial (B) and coronal (C) planes with areas of sclerosis (asterisks) and erosions (arrows) in both joint margins.</p>" ] ] ] "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 67-year-old woman presented with a 5-year history of mechanical thoracolumbar pain that responded satisfactorily to nonsteroidal anti-inflammatory agents. She had intermittent inflammatory low back pain since the age of 25 years, and 2 episodes of acute anterior uveitis at 30 and 32 years of age, respectively. She had 2 siblings who had been diagnosed as having human lymphocyte antigen (HLA)-B27-positive ankylosing spondylitis (AS). Physical examination revealed limited axial mobility (modified Schöber test: 2.5<span class="elsevierStyleHsp" style=""></span>cm) and chest expansion (2<span class="elsevierStyleHsp" style=""></span>cm), and bilateral positive sacroiliac maneuvers. The results of her analyses were normal (erythrocyte sedimentation rate 16<span class="elsevierStyleHsp" style=""></span>mm/h; C-reactive protein 2.6<span class="elsevierStyleHsp" style=""></span>mg/dL) and she was HLA-B27-positive. Thoracic spine radiographs showed bone bridges on right anterolateral aspect of 4 contiguous vertebrae (<a class="elsevierStyleCrossRef" href="#fig0005">Fig. 1</a>) compatible with Forestier-Rotés-Quérol disease, or diffuse idiopathic skeletal hyperostosis (DISH), and, in pelvis, bilateral grade 3 sacroiliitis (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>A). Computed tomography (CT) of the sacroiliac joints revealed sclerosis and erosions (<a class="elsevierStyleCrossRef" href="#fig0010">Fig. 2</a>B and C), confirming the coexistence of AS and DISH.</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><elsevierMultimedia ident="fig0010"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Ankylosing spondylitis and DISH have similar rates of new bone formation and functional limitations.<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">1,2</span></a> However, AS has an inflammatory basis, develops in individuals of less than 40 years of age, and is associated with HLA-B27 (90%), whereas DISH has a metabolic basis, appears in those over the age of 50, and is not associated with HLA-B27 (8%).<a class="elsevierStyleCrossRef" href="#bib0060"><span class="elsevierStyleSup">3</span></a> The type of vertebral bone formation also differs; AS is characterized by “typical syndesmophytes” that are vertical and narrow and originate in the annulus fibrosus, whereas DISH shows bone excrescences that begin in the anterior longitudinal ligament and paravertebral tissues, forming angles >45°.<a class="elsevierStyleCrossRefs" href="#bib0050"><span class="elsevierStyleSup">1,4</span></a> Diffuse idiopathic skeletal hyperostosis affects the sacroiliac joints in their most cranial portion (ligamentous), with vacuum phenomenon, joint space narrowing, sclerosis and even ankylosis, which can be confused with grade 4 sacroiliitis in plain radiographs (and CT is useful in these cases), but without inflammatory changes or erosions.<a class="elsevierStyleCrossRefs" href="#bib0060"><span class="elsevierStyleSup">3,5,6</span></a> These 2 disorders are not mutually exclusive and can coexist, although few cases have been reported (16 according to the literature).<a class="elsevierStyleCrossRefs" href="#bib0080"><span class="elsevierStyleSup">7–9</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Ethical Disclosures</span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Protection of human and animal subjects</span><p id="par0015" class="elsevierStylePara elsevierViewall">The authors declare that no experiments were performed on humans or animals for this study.</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Confidentiality of data</span><p id="par0020" class="elsevierStylePara elsevierViewall">The authors declare that they have followed the protocols of their work center on the publication of patient data.</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Right to privacy and informed consent</span><p id="par0025" class="elsevierStylePara elsevierViewall">The authors have obtained the written informed consent of the patients or subjects mentioned in the article. The corresponding author is in possession of this document.</p></span></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Conflicts of Interest</span><p id="par0030" class="elsevierStylePara elsevierViewall">The authors declare they have no conflicts of interest concerning the publication of this article.</p></span></span>" "textoCompletoSecciones" => array:1 [ "secciones" => array:3 [ 0 => array:3 [ "identificador" => "sec0005" "titulo" => "Ethical Disclosures" "secciones" => array:3 [ 0 => array:2 [ "identificador" => "sec0010" "titulo" => "Protection of human and animal subjects" ] 1 => array:2 [ "identificador" => "sec0015" "titulo" => "Confidentiality of data" ] 2 => array:2 [ "identificador" => "sec0020" "titulo" => "Right to privacy and informed consent" ] ] ] 1 => array:2 [ "identificador" => "sec0025" "titulo" => "Conflicts of Interest" ] 2 => array:1 [ "titulo" => "References" ] ] ] "pdfFichero" => "main.pdf" "tienePdf" => true "fechaRecibido" => "2016-03-01" "fechaAceptado" => "2016-03-24" "NotaPie" => array:1 [ 0 => array:2 [ "etiqueta" => "☆" "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as: Macía-Villa CC, Sifuentes-Giraldo WA, Medina-Luezas J. Presentación simultánea de espondilitis anquilosante e hiperostosis esquelética idiopática difusa (enfermedad de Forestier-Rotès-Quérol). Reumatol Clin. 2017;13:237–238.</p>" ] ] "multimedia" => array:2 [ 0 => array:7 [ "identificador" => "fig0005" "etiqueta" => "Fig. 1" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr1.jpeg" "Alto" => 1126 "Ancho" => 1501 "Tamanyo" => 165352 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Anteroposterior (A) and lateral (B) radiographs of thoracic spine showing the bone bridges in right anterolateral aspect of 4 contiguous vertebral bodies (white arrows) consistent with the diagnosis of diffuse idiopathic skeletal hyperostosis (DISH). The lateral radiograph also reveals that these bone bridges form angles of more than 45° with the vertebral border.</p>" ] ] 1 => array:7 [ "identificador" => "fig0010" "etiqueta" => "Fig. 2" "tipo" => "MULTIMEDIAFIGURA" "mostrarFloat" => true "mostrarDisplay" => false "figura" => array:1 [ 0 => array:4 [ "imagen" => "gr2.jpeg" "Alto" => 758 "Ancho" => 2667 "Tamanyo" => 206721 ] ] "descripcion" => array:1 [ "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Radiograph of pelvis (A) showing sclerosis, joint space narrowing and erosions in right sacroiliac joint and sclerosis and pseudo-widening on the left (bilateral grade 3 sacroiliitis). Computed tomography of sacroiliac joints showing axial (B) and coronal (C) planes with areas of sclerosis (asterisks) and erosions (arrows) in both joint margins.</p>" ] ] ] "bibliografia" => array:2 [ "titulo" => "References" "seccion" => array:1 [ 0 => array:2 [ "identificador" => "bibs0005" "bibliografiaReferencia" => array:9 [ 0 => array:3 [ "identificador" => "bib0050" "etiqueta" => "1" "referencia" => array:1 [ 0 => array:2 [ "contribucion" => array:1 [ 0 => array:2 [ "titulo" => "A comparison of new bone formation in patients with ankylosing spondylitis and patients with diffuse idiopathic skeletal hyperostosis: a retrospective cohort study over six years" "autores" => array:1 [ 0 => array:2 [ "etal" => false "autores" => array:5 [ 0 => "X. Baraliakos" 1 => "J. Listing" 2 => "J. Buschmann" 3 => "A. von der Recke" 4 => "J. 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Year/Month | Html | Total | |
---|---|---|---|
2024 November | 12 | 10 | 22 |
2024 October | 79 | 37 | 116 |
2024 September | 91 | 12 | 103 |
2024 August | 106 | 35 | 141 |
2024 July | 98 | 30 | 128 |
2024 June | 76 | 26 | 102 |
2024 May | 84 | 30 | 114 |
2024 April | 75 | 10 | 85 |
2024 March | 93 | 35 | 128 |
2024 February | 73 | 20 | 93 |
2024 January | 75 | 22 | 97 |
2023 December | 68 | 42 | 110 |
2023 November | 69 | 37 | 106 |
2023 October | 100 | 32 | 132 |
2023 September | 84 | 43 | 127 |
2023 August | 72 | 10 | 82 |
2023 July | 90 | 28 | 118 |
2023 June | 75 | 15 | 90 |
2023 May | 75 | 21 | 96 |
2023 April | 76 | 9 | 85 |
2023 March | 100 | 35 | 135 |
2023 February | 79 | 21 | 100 |
2023 January | 100 | 17 | 117 |
2022 December | 73 | 43 | 116 |
2022 November | 81 | 33 | 114 |
2022 October | 89 | 26 | 115 |
2022 September | 79 | 36 | 115 |
2022 August | 89 | 45 | 134 |
2022 July | 75 | 46 | 121 |
2022 June | 69 | 31 | 100 |
2022 May | 83 | 32 | 115 |
2022 April | 82 | 37 | 119 |
2022 March | 65 | 45 | 110 |
2022 February | 87 | 30 | 117 |
2022 January | 124 | 39 | 163 |
2021 December | 59 | 45 | 104 |
2021 November | 79 | 43 | 122 |
2021 October | 68 | 51 | 119 |
2021 September | 78 | 41 | 119 |
2021 August | 51 | 37 | 88 |
2021 July | 61 | 33 | 94 |
2021 June | 61 | 35 | 96 |
2021 May | 70 | 76 | 146 |
2021 April | 150 | 118 | 268 |
2021 March | 90 | 35 | 125 |
2021 February | 51 | 28 | 79 |
2021 January | 49 | 22 | 71 |
2020 December | 61 | 23 | 84 |
2020 November | 60 | 26 | 86 |
2020 October | 45 | 10 | 55 |
2020 September | 62 | 25 | 87 |
2020 August | 51 | 19 | 70 |
2020 July | 40 | 21 | 61 |
2020 June | 38 | 24 | 62 |
2020 May | 43 | 15 | 58 |
2020 April | 25 | 12 | 37 |
2020 March | 15 | 11 | 26 |
2019 February | 1 | 0 | 1 |
2018 December | 2 | 0 | 2 |
2018 May | 5 | 1 | 6 |
2018 April | 87 | 6 | 93 |
2018 March | 143 | 9 | 152 |
2018 February | 51 | 11 | 62 |
2018 January | 46 | 2 | 48 |
2017 December | 54 | 11 | 65 |
2017 November | 42 | 9 | 51 |
2017 October | 44 | 11 | 55 |
2017 September | 52 | 12 | 64 |
2017 August | 69 | 24 | 93 |
2017 July | 53 | 33 | 86 |
2017 June | 19 | 14 | 33 |
2017 May | 31 | 15 | 46 |
2017 April | 12 | 14 | 26 |
2017 March | 10 | 17 | 27 |
2017 February | 1 | 4 | 5 |