array:24 [
  "pii" => "S2173574317300394"
  "issn" => "21735743"
  "doi" => "10.1016/j.reumae.2016.04.008"
  "estado" => "S300"
  "fechaPublicacion" => "2017-09-01"
  "aid" => "915"
  "copyright" => "Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología"
  "copyrightAnyo" => "2016"
  "documento" => "simple-article"
  "crossmark" => 1
  "subdocumento" => "crp"
  "cita" => "Reumatol Clin. 2017;13:297-8"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 889
    "formatos" => array:3 [
      "EPUB" => 72
      "HTML" => 625
      "PDF" => 192
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S1699258X16300146"
      "issn" => "1699258X"
      "doi" => "10.1016/j.reuma.2016.04.002"
      "estado" => "S300"
      "fechaPublicacion" => "2017-09-01"
      "aid" => "915"
      "copyright" => "Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología"
      "documento" => "simple-article"
      "crossmark" => 1
      "subdocumento" => "crp"
      "cita" => "Reumatol Clin. 2017;13:297-8"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 41101
        "formatos" => array:3 [
          "EPUB" => 265
          "HTML" => 39048
          "PDF" => 1788
        ]
      ]
      "es" => array:13 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Caso cl&#237;nico</span>"
        "titulo" => "Vasculitis leucocitocl&#225;stica e infecci&#243;n&#46; A prop&#243;sito de un caso"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "297"
            "paginaFinal" => "298"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Leukocytoclastic vasculitis and infection&#46; Report of a case"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 673
                "Ancho" => 1500
                "Tamanyo" => 105545
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Forma vesiculoampollosa de vasculitis leucocitocl&#225;stica cut&#225;nea&#46; A&#41; Antes del tratamiento antibi&#243;tico&#46; B&#41; Despu&#233;s del tratamiento antibi&#243;tico&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Mar&#237;a Jose Moreno Mart&#237;nez, Deseada Palma S&#225;nchez, Elena Pe&#241;as Mart&#237;nez, Ana Haro Mart&#237;nez, Marta Mayor Gonz&#225;lez"
            "autores" => array:5 [
              0 => array:2 [
                "nombre" => "Mar&#237;a Jose"
                "apellidos" => "Moreno Mart&#237;nez"
              ]
              1 => array:2 [
                "nombre" => "Deseada"
                "apellidos" => "Palma S&#225;nchez"
              ]
              2 => array:2 [
                "nombre" => "Elena"
                "apellidos" => "Pe&#241;as Mart&#237;nez"
              ]
              3 => array:2 [
                "nombre" => "Ana"
                "apellidos" => "Haro Mart&#237;nez"
              ]
              4 => array:2 [
                "nombre" => "Marta"
                "apellidos" => "Mayor Gonz&#225;lez"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2173574317300394"
          "doi" => "10.1016/j.reumae.2016.04.008"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => false
            "ES2" => false
            "LATM" => false
          ]
          "gratuito" => false
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574317300394?idApp=UINPBA00004M"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X16300146?idApp=UINPBA00004M"
      "url" => "/1699258X/0000001300000005/v1_201708130010/S1699258X16300146/v1_201708130010/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2173574317300928"
    "issn" => "21735743"
    "doi" => "10.1016/j.reumae.2016.07.009"
    "estado" => "S300"
    "fechaPublicacion" => "2017-09-01"
    "aid" => "947"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Reumatolog&#237;a y Colegio Mexicano de Reumatolog&#237;a"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "sco"
    "cita" => "Reumatol Clin. 2017;13:299-300"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 987
      "formatos" => array:3 [
        "EPUB" => 44
        "HTML" => 776
        "PDF" => 167
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Images in Clinical Rheumatology</span>"
      "titulo" => "Van Neck-Odelberg Disease&#58; Another Cause of Limp in Childhood"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "299"
          "paginaFinal" => "300"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Enfermedad de Van Neck-Odelberg&#58; una causa m&#225;s de cojera en la infancia"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Fig&#46; 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 643
              "Ancho" => 1040
              "Tamanyo" => 88738
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Axial magnetic resonance imaging &#40;short tau inversion recovery&#41; of pelvis&#58; swelling of right ischiopubic synchondrosis&#44; with irregular margins&#46; Signal alteration in bone marrow and edema of the surrounding soft tissue&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Isla Morante Bolado, Marina Ortega Navaridas, Daniel Clemente Garulo, Juan Carlos L&#243;pez Robledillo"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Isla"
              "apellidos" => "Morante Bolado"
            ]
            1 => array:2 [
              "nombre" => "Marina"
              "apellidos" => "Ortega Navaridas"
            ]
            2 => array:2 [
              "nombre" => "Daniel"
              "apellidos" => "Clemente Garulo"
            ]
            3 => array:2 [
              "nombre" => "Juan Carlos"
              "apellidos" => "L&#243;pez Robledillo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S1699258X16300663"
        "doi" => "10.1016/j.reuma.2016.07.001"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X16300663?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574317300928?idApp=UINPBA00004M"
    "url" => "/21735743/0000001300000005/v1_201708230012/S2173574317300928/v1_201708230012/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173574317300576"
    "issn" => "21735743"
    "doi" => "10.1016/j.reumae.2017.04.001"
    "estado" => "S300"
    "fechaPublicacion" => "2017-09-01"
    "aid" => "922"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Reumatolog&#237;a y Colegio Mexicano de Reumatolog&#237;a"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "crp"
    "cita" => "Reumatol Clin. 2017;13:294-6"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 1052
      "formatos" => array:3 [
        "EPUB" => 63
        "HTML" => 759
        "PDF" => 230
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case Report</span>"
      "titulo" => "Relapsed Hydroxychloroquine Induced Thrombocytopenia in Systemic Lupus Erythematosus Patient"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "294"
          "paginaFinal" => "296"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Trombocitopenia recurrente inducida por hidroxicloroquina en ausencia de actividad del lupus eritematoso sist&#233;mico"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 578
              "Ancho" => 1524
              "Tamanyo" => 71373
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Changes in platelet counts in relation to exposure to hydroxychloroquine &#40;HCQ&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Vanesa Ant&#243;n V&#225;zquez, Luis Pascual, H&#233;ctor Corominas Macias, Isabel Gim&#233;nez Torrecilla"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Vanesa Ant&#243;n"
              "apellidos" => "V&#225;zquez"
            ]
            1 => array:2 [
              "nombre" => "Luis"
              "apellidos" => "Pascual"
            ]
            2 => array:2 [
              "nombre" => "H&#233;ctor"
              "apellidos" => "Corominas Macias"
            ]
            3 => array:2 [
              "nombre" => "Isabel"
              "apellidos" => "Gim&#233;nez Torrecilla"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S1699258X16300249"
        "doi" => "10.1016/j.reuma.2016.04.008"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X16300249?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574317300576?idApp=UINPBA00004M"
    "url" => "/21735743/0000001300000005/v1_201708230012/S2173574317300576/v1_201708230012/en/main.assets"
  ]
  "en" => array:20 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case report</span>"
    "titulo" => "Leukocytoclastic Vasculitis and Infection&#46; Report of a Case"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "297"
        "paginaFinal" => "298"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Mar&#237;a Jose Moreno Mart&#237;nez, Deseada Palma S&#225;nchez, Elena Pe&#241;as Mart&#237;nez, Ana Haro Mart&#237;nez, Marta Mayor Gonz&#225;lez"
        "autores" => array:5 [
          0 => array:4 [
            "nombre" => "Mar&#237;a Jose"
            "apellidos" => "Moreno Mart&#237;nez"
            "email" => array:1 [
              0 => "mjmorenomartinez&#64;gmail&#46;com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "Deseada"
            "apellidos" => "Palma S&#225;nchez"
          ]
          2 => array:2 [
            "nombre" => "Elena"
            "apellidos" => "Pe&#241;as Mart&#237;nez"
          ]
          3 => array:2 [
            "nombre" => "Ana"
            "apellidos" => "Haro Mart&#237;nez"
          ]
          4 => array:2 [
            "nombre" => "Marta"
            "apellidos" => "Mayor Gonz&#225;lez"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Hospital Rafael M&#233;ndez&#44; Lorca&#44; Murcia&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Vasculitis leucocitocl&#225;stica e infecci&#243;n&#46; A prop&#243;sito de un caso"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 673
            "Ancho" => 1500
            "Tamanyo" => 100367
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Vesiculobullous form of cutaneous leukocytoclastic vasculitis&#46; &#40;A&#41; Prior to antibiotic therapy&#46; &#40;B&#41; After antibiotic therapy&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Cutaneous vasculitides are inflammatory disorders affecting the wall of the vessels of the skin&#46; There can be a number of causes &#40;drug exposure&#44; infection&#44; neoplastic disease or systemic inflammatory disease&#41;&#44;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> and skin involvement may be its only manifestation&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Leukocytoclastic vasculitis is the most frequent cause of cutaneous vasculitis found in clinical practice&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> On occasion&#44; it can be associated with constitutional symptoms&#44; and thus be confused with systemic diseases and certain conditions like mycoplasma&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Ureaplasma</span>&#44; which belongs to the same family as <span class="elsevierStyleItalic">Mycoplasma</span>&#44; is associated&#44; in adults&#44; with genital infections like nongonococcal urethritis&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a></p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Clinical Observation</span><p id="par0020" class="elsevierStylePara elsevierViewall">We present the case of a 28-year-old man who had no significant previous medical history&#46; He presented at the emergency service with lesions in the skin on lower limbs and trunk that did not disappear when pressed by a finger&#46; The patient had no other systemic symptoms&#46; He did not have fever or signs of infection anywhere else&#44; except certain genital symptoms that were not well defined&#46; He denied the use of drugs&#44; sexual risk behavior and the consumption of any type of medication&#46; He had arthralgia but not arthritis and&#44; on the level of the skin&#44; he had flat&#44; erythematous&#44; nonpruritic lesions&#44; together with other bullous lesions &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; He underwent a skin biopsy which revealed leukocytoclastic vasculitis &#40;perivascular inflammatory infiltrate with predominance of neutrophils&#44; and nuclear dust&#44; fibrinoid degeneration and extravasated red blood cells&#59; subepidermal blisters with hemorrhagic and pustular content and focal epidermal necrosis&#41;&#46; The analytical study&#44; which involved acute-phase reactants&#44; complete blood count and biochemical and immunological data&#44; was normal&#46; A urine culture was negative&#44; as were serological tests for the hepatotropic viruses&#46; Colonies of <span class="elsevierStyleItalic">Ureaplasma urealyticum</span> were identified in the urethral exudate&#46; At admission&#44; treatment was begun with prednisone &#40;30<span class="elsevierStyleHsp" style=""></span>mg&#47;day&#41; and a nonsteroidal anti-inflammatory drug &#40;ibuprofen at 600<span class="elsevierStyleHsp" style=""></span>mg every 8<span class="elsevierStyleHsp" style=""></span>h&#41;&#46; This was followed by clinical improvement&#59; however&#44; it did not persist until antibiotic therapy was initiated with doxycycline&#44; in accordance with antibiogram indications for <span class="elsevierStyleItalic">Ureaplasma</span>&#46; Steroids were discontinued after 1 month and&#44; 6 months later&#44; the patient was asymptomatic without treatment&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Discussion</span><p id="par0025" class="elsevierStylePara elsevierViewall">Leukocytoclastic vasculitis is the most common cutaneous vasculitis&#46; Although in 50&#37; of the cases&#44; the cause is usually idiopathic&#44; the histopathological diagnosis enabled by biopsy should be established as soon as possible to rule out other possibilities such as systemic&#44; neoplastic or infectious diseases&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">1&#44;3&#8211;5</span></a> Nevertheless&#44; the term &#8220;leukocytoclastic vasculitis&#8221; does not specify the exact diagnosis&#46;<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">4&#44;5</span></a> In sexually active patients&#44; we cannot forget that sexually transmitted diseases&#44; which include <span class="elsevierStyleItalic">Ureaplasma</span> infection&#44; can be asymptomatic and are related to a wide variety of pathological settings&#44; one of which is leukocytoclastic vasculitis&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">With regard to the treatment of leukocytoclastic vasculitis&#44; the first situation that should be treated is the triggering factor&#44;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a><span class="elsevierStyleItalic">Ureaplasma</span> infection in our patient&#44; leaving immunosuppressive therapy for cases that are refractory or in which the involvement is severe&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a></p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Conclusions</span><p id="par0035" class="elsevierStylePara elsevierViewall">There are many factors that can be associated with leukocytoclastic vasculitis as triggers of the disease&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Infections are a frequent cause of cutaneous vasculitis and joint involvement&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">There are infections in which the symptoms are less evident that should be taken into account in the examination of our patients&#44; because there may be a causal relationship&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Ethical Disclosures</span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Protection of human and animal subjects</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors declare that no experiments were performed on humans or animals for this study&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Confidentiality of data</span><p id="par0055" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Right to privacy and informed consent</span><p id="par0060" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Conflicts of Interest</span><p id="par0065" class="elsevierStylePara elsevierViewall">The authors declare they have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:11 [
        0 => array:3 [
          "identificador" => "xres884942"
          "titulo" => "Abstract"
          "secciones" => array:1 [
            0 => array:1 [
              "identificador" => "abst0005"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec871142"
          "titulo" => "Keywords"
        ]
        2 => array:3 [
          "identificador" => "xres884943"
          "titulo" => "Resumen"
          "secciones" => array:1 [
            0 => array:1 [
              "identificador" => "abst0010"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec871141"
          "titulo" => "Palabras clave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Clinical Observation"
        ]
        6 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Discussion"
        ]
        7 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Conclusions"
        ]
        8 => array:3 [
          "identificador" => "sec0025"
          "titulo" => "Ethical Disclosures"
          "secciones" => array:3 [
            0 => array:2 [
              "identificador" => "sec0030"
              "titulo" => "Protection of human and animal subjects"
            ]
            1 => array:2 [
              "identificador" => "sec0035"
              "titulo" => "Confidentiality of data"
            ]
            2 => array:2 [
              "identificador" => "sec0040"
              "titulo" => "Right to privacy and informed consent"
            ]
          ]
        ]
        9 => array:2 [
          "identificador" => "sec0045"
          "titulo" => "Conflicts of Interest"
        ]
        10 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2016-01-25"
    "fechaAceptado" => "2016-04-08"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec871142"
          "palabras" => array:4 [
            0 => "Cutaneous vasculitis"
            1 => "Infection"
            2 => "<span class="elsevierStyleItalic">Ureaplasma urealyticum</span>"
            3 => "Leukocytoclastic vasculitis"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec871141"
          "palabras" => array:4 [
            0 => "Vasculitis cut&#225;nea"
            1 => "Infecci&#243;n"
            2 => "<span class="elsevierStyleItalic">Ureaplasma urealyticum</span>"
            3 => "Vasculitis leucocitocl&#225;stica"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Leukocytoclastic vasculitis is the most common cause of cutaneous vasculitis in clinical practice&#46; Its causes are various&#44; among which are certain infections&#46; We report the case of a man &#40;28 years old&#41; who debuted with vasculitic lesions in inferior members compatibles leukocytoclastic vasculitis on pathology&#46; The study of causation is the presence of a positive urethral discharge to <span class="elsevierStyleItalic">Ureaplasma urealyticum</span>&#44; dramatically improving lesions after treatment thereof&#46;</p></span>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">La vasculitis leucocitocl&#225;stica es la causa m&#225;s frecuente de vasculitis cut&#225;nea en la pr&#225;ctica cl&#237;nica&#46; Sus causas son diversas&#44; entre las que se encuentran ciertas infecciones&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Presentamos el caso de un var&#243;n de 28 a&#241;os que debuta con lesiones vascul&#237;ticas en miembros inferiores&#44; compatibles con una vasculitis leucocitocl&#225;stica en la anatom&#237;a patol&#243;gica&#46; En el estudio de causalidad se encuentra la presencia de un exudado uretral positivo a <span class="elsevierStyleItalic">Ureaplasma urealyticum</span>&#44; mejorando dr&#225;sticamente las lesiones tras el tratamiento del mismo&#46;</p></span>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Moreno Mart&#237;nez MJ&#44; Palma S&#225;nchez D&#44; Pe&#241;as Mart&#237;nez E&#44; Haro Mart&#237;nez A&#44; Mayor Gonz&#225;lez M&#46; Vasculitis leucocitocl&#225;stica e infecci&#243;n&#46; A prop&#243;sito de un caso&#46; Reumatol Clin&#46; 2017&#59;13&#58;297&#8211;298&#46;</p>"
      ]
    ]
    "multimedia" => array:1 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 673
            "Ancho" => 1500
            "Tamanyo" => 100367
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Vesiculobullous form of cutaneous leukocytoclastic vasculitis&#46; &#40;A&#41; Prior to antibiotic therapy&#46; &#40;B&#41; After antibiotic therapy&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Vasculitis cut&#225;neas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46; Pulido-P&#233;rez"
                            1 => "J&#46;A&#46; Avil&#233;s-Izquierdo"
                            2 => "R&#46; Su&#225;rez-Fern&#225;ndez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ad.2011.06.001"
                      "Revista" => array:6 [
                        "tituloSerie" => "Actas Dermosifiliogr"
                        "fecha" => "2012"
                        "volumen" => "103"
                        "paginaInicial" => "179"
                        "paginaFinal" => "191"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21839977"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:3 [
                  "comentario" => "Available from&#58; <span class="elsevierStyleInterRef" id="intr0010" href="http://www.ine.gov.ar/documentos/publicaciones/028.pdf">http&#58;&#47;&#47;www&#46;ine&#46;gov&#46;ar&#47;documentos&#47;publicaciones&#47;028&#46;pdf</span> &#91;accessed 18&#46;11&#46;15&#93;"
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Infecciones de transmisi&#243;n sexual por <span class="elsevierStyleItalic">Ureaplasma urealyticum</span> y <span class="elsevierStyleItalic">Mycoplasma hominis</span>"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46;M&#46; Zotta"
                            1 => "D&#46; G&#243;mez"
                            2 => "S&#46; Lavay&#233;n"
                            3 => "M&#46;G&#46; Galeano"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "SaludiCiencia"
                        "fecha" => "2013"
                        "volumen" => "20"
                        "paginaInicial" => "37"
                        "paginaFinal" => "40"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A practical approach to the diagnosis&#44; evaluation&#44; and management of cutaneous small-vessel vasculitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46;R&#46; Goeser"
                            1 => "V&#46; Laniosz"
                            2 => "D&#46;A&#46; Wetter"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s40257-014-0076-6"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Clin Dermatol"
                        "fecha" => "2014"
                        "volumen" => "15"
                        "paginaInicial" => "299"
                        "paginaFinal" => "306"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24756249"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous manifestations of vasculitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "L&#46; Xu"
                            1 => "E&#46; Esparza"
                            2 => "M&#46; Anadkat"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.semarthrit.2008.01.007"
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Arthritis Rheum"
                        "fecha" => "2009"
                        "volumen" => "38"
                        "paginaInicial" => "348"
                        "paginaFinal" => "360"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18355896"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Skin involvement in cutaneous and systemic vasculitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46;V&#46; Marzano"
                            1 => "P&#46; Vezzoli"
                            2 => "E&#46; Berti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.autrev.2012.08.005"
                      "Revista" => array:7 [
                        "tituloSerie" => "Autoimmun Rev"
                        "fecha" => "2013"
                        "volumen" => "12"
                        "paginaInicial" => "467"
                        "paginaFinal" => "476"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22959234"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0140673613616475"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735743/0000001300000005/v1_201708230012/S2173574317300394/v1_201708230012/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "67860"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case reports"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735743/0000001300000005/v1_201708230012/S2173574317300394/v1_201708230012/en/main.pdf?idApp=UINPBA00004M&text.app=https://reumatologiaclinica.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574317300394?idApp=UINPBA00004M"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Case report
Leukocytoclastic Vasculitis and Infection. Report of a Case
Vasculitis leucocitoclástica e infección. A propósito de un caso
María Jose Moreno Martínez
Corresponding author
mjmorenomartinez@gmail.com

Corresponding author.
, Deseada Palma Sánchez, Elena Peñas Martínez, Ana Haro Martínez, Marta Mayor González
Hospital Rafael Méndez, Lorca, Murcia, Spain
Read
8983
Times
was read the article
2196
Total PDF
6787
Total HTML
Share statistics
 array:24 [
  "pii" => "S2173574317300394"
  "issn" => "21735743"
  "doi" => "10.1016/j.reumae.2016.04.008"
  "estado" => "S300"
  "fechaPublicacion" => "2017-09-01"
  "aid" => "915"
  "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Reumatolog&#237;a y Colegio Mexicano de Reumatolog&#237;a"
  "copyrightAnyo" => "2016"
  "documento" => "simple-article"
  "crossmark" => 1
  "subdocumento" => "crp"
  "cita" => "Reumatol Clin. 2017;13:297-8"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 889
    "formatos" => array:3 [
      "EPUB" => 72
      "HTML" => 625
      "PDF" => 192
    ]
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S1699258X16300146"
      "issn" => "1699258X"
      "doi" => "10.1016/j.reuma.2016.04.002"
      "estado" => "S300"
      "fechaPublicacion" => "2017-09-01"
      "aid" => "915"
      "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Reumatolog&#237;a y Colegio Mexicano de Reumatolog&#237;a"
      "documento" => "simple-article"
      "crossmark" => 1
      "subdocumento" => "crp"
      "cita" => "Reumatol Clin. 2017;13:297-8"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 41101
        "formatos" => array:3 [
          "EPUB" => 265
          "HTML" => 39048
          "PDF" => 1788
        ]
      ]
      "es" => array:13 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Caso cl&#237;nico</span>"
        "titulo" => "Vasculitis leucocitocl&#225;stica e infecci&#243;n&#46; A prop&#243;sito de un caso"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "tieneResumen" => array:2 [
          0 => "es"
          1 => "en"
        ]
        "paginas" => array:1 [
          0 => array:2 [
            "paginaInicial" => "297"
            "paginaFinal" => "298"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Leukocytoclastic vasculitis and infection&#46; Report of a case"
          ]
        ]
        "contieneResumen" => array:2 [
          "es" => true
          "en" => true
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 673
                "Ancho" => 1500
                "Tamanyo" => 105545
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Forma vesiculoampollosa de vasculitis leucocitocl&#225;stica cut&#225;nea&#46; A&#41; Antes del tratamiento antibi&#243;tico&#46; B&#41; Despu&#233;s del tratamiento antibi&#243;tico&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Mar&#237;a Jose Moreno Mart&#237;nez, Deseada Palma S&#225;nchez, Elena Pe&#241;as Mart&#237;nez, Ana Haro Mart&#237;nez, Marta Mayor Gonz&#225;lez"
            "autores" => array:5 [
              0 => array:2 [
                "nombre" => "Mar&#237;a Jose"
                "apellidos" => "Moreno Mart&#237;nez"
              ]
              1 => array:2 [
                "nombre" => "Deseada"
                "apellidos" => "Palma S&#225;nchez"
              ]
              2 => array:2 [
                "nombre" => "Elena"
                "apellidos" => "Pe&#241;as Mart&#237;nez"
              ]
              3 => array:2 [
                "nombre" => "Ana"
                "apellidos" => "Haro Mart&#237;nez"
              ]
              4 => array:2 [
                "nombre" => "Marta"
                "apellidos" => "Mayor Gonz&#225;lez"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2173574317300394"
          "doi" => "10.1016/j.reumae.2016.04.008"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => false
            "ES2" => false
            "LATM" => false
          ]
          "gratuito" => false
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574317300394?idApp=UINPBA00004M"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X16300146?idApp=UINPBA00004M"
      "url" => "/1699258X/0000001300000005/v1_201708130010/S1699258X16300146/v1_201708130010/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2173574317300928"
    "issn" => "21735743"
    "doi" => "10.1016/j.reumae.2016.07.009"
    "estado" => "S300"
    "fechaPublicacion" => "2017-09-01"
    "aid" => "947"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Reumatolog&#237;a y Colegio Mexicano de Reumatolog&#237;a"
    "documento" => "article"
    "crossmark" => 1
    "subdocumento" => "sco"
    "cita" => "Reumatol Clin. 2017;13:299-300"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 987
      "formatos" => array:3 [
        "EPUB" => 44
        "HTML" => 776
        "PDF" => 167
      ]
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Images in Clinical Rheumatology</span>"
      "titulo" => "Van Neck-Odelberg Disease&#58; Another Cause of Limp in Childhood"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "299"
          "paginaFinal" => "300"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Enfermedad de Van Neck-Odelberg&#58; una causa m&#225;s de cojera en la infancia"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0010"
          "etiqueta" => "Fig&#46; 2"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr2.jpeg"
              "Alto" => 643
              "Ancho" => 1040
              "Tamanyo" => 88738
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">Axial magnetic resonance imaging &#40;short tau inversion recovery&#41; of pelvis&#58; swelling of right ischiopubic synchondrosis&#44; with irregular margins&#46; Signal alteration in bone marrow and edema of the surrounding soft tissue&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Isla Morante Bolado, Marina Ortega Navaridas, Daniel Clemente Garulo, Juan Carlos L&#243;pez Robledillo"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Isla"
              "apellidos" => "Morante Bolado"
            ]
            1 => array:2 [
              "nombre" => "Marina"
              "apellidos" => "Ortega Navaridas"
            ]
            2 => array:2 [
              "nombre" => "Daniel"
              "apellidos" => "Clemente Garulo"
            ]
            3 => array:2 [
              "nombre" => "Juan Carlos"
              "apellidos" => "L&#243;pez Robledillo"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S1699258X16300663"
        "doi" => "10.1016/j.reuma.2016.07.001"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X16300663?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574317300928?idApp=UINPBA00004M"
    "url" => "/21735743/0000001300000005/v1_201708230012/S2173574317300928/v1_201708230012/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173574317300576"
    "issn" => "21735743"
    "doi" => "10.1016/j.reumae.2017.04.001"
    "estado" => "S300"
    "fechaPublicacion" => "2017-09-01"
    "aid" => "922"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Reumatolog&#237;a y Colegio Mexicano de Reumatolog&#237;a"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "crp"
    "cita" => "Reumatol Clin. 2017;13:294-6"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 1052
      "formatos" => array:3 [
        "EPUB" => 63
        "HTML" => 759
        "PDF" => 230
      ]
    ]
    "en" => array:13 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Case Report</span>"
      "titulo" => "Relapsed Hydroxychloroquine Induced Thrombocytopenia in Systemic Lupus Erythematosus Patient"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "tieneResumen" => array:2 [
        0 => "en"
        1 => "es"
      ]
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "294"
          "paginaFinal" => "296"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Trombocitopenia recurrente inducida por hidroxicloroquina en ausencia de actividad del lupus eritematoso sist&#233;mico"
        ]
      ]
      "contieneResumen" => array:2 [
        "en" => true
        "es" => true
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 578
              "Ancho" => 1524
              "Tamanyo" => 71373
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Changes in platelet counts in relation to exposure to hydroxychloroquine &#40;HCQ&#41;&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Vanesa Ant&#243;n V&#225;zquez, Luis Pascual, H&#233;ctor Corominas Macias, Isabel Gim&#233;nez Torrecilla"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Vanesa Ant&#243;n"
              "apellidos" => "V&#225;zquez"
            ]
            1 => array:2 [
              "nombre" => "Luis"
              "apellidos" => "Pascual"
            ]
            2 => array:2 [
              "nombre" => "H&#233;ctor"
              "apellidos" => "Corominas Macias"
            ]
            3 => array:2 [
              "nombre" => "Isabel"
              "apellidos" => "Gim&#233;nez Torrecilla"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S1699258X16300249"
        "doi" => "10.1016/j.reuma.2016.04.008"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X16300249?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574317300576?idApp=UINPBA00004M"
    "url" => "/21735743/0000001300000005/v1_201708230012/S2173574317300576/v1_201708230012/en/main.assets"
  ]
  "en" => array:20 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Case report</span>"
    "titulo" => "Leukocytoclastic Vasculitis and Infection&#46; Report of a Case"
    "tieneTextoCompleto" => true
    "paginas" => array:1 [
      0 => array:2 [
        "paginaInicial" => "297"
        "paginaFinal" => "298"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Mar&#237;a Jose Moreno Mart&#237;nez, Deseada Palma S&#225;nchez, Elena Pe&#241;as Mart&#237;nez, Ana Haro Mart&#237;nez, Marta Mayor Gonz&#225;lez"
        "autores" => array:5 [
          0 => array:4 [
            "nombre" => "Mar&#237;a Jose"
            "apellidos" => "Moreno Mart&#237;nez"
            "email" => array:1 [
              0 => "mjmorenomartinez&#64;gmail&#46;com"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "<span class="elsevierStyleSup">&#42;</span>"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "Deseada"
            "apellidos" => "Palma S&#225;nchez"
          ]
          2 => array:2 [
            "nombre" => "Elena"
            "apellidos" => "Pe&#241;as Mart&#237;nez"
          ]
          3 => array:2 [
            "nombre" => "Ana"
            "apellidos" => "Haro Mart&#237;nez"
          ]
          4 => array:2 [
            "nombre" => "Marta"
            "apellidos" => "Mayor Gonz&#225;lez"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Hospital Rafael M&#233;ndez&#44; Lorca&#44; Murcia&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Vasculitis leucocitocl&#225;stica e infecci&#243;n&#46; A prop&#243;sito de un caso"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 673
            "Ancho" => 1500
            "Tamanyo" => 100367
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Vesiculobullous form of cutaneous leukocytoclastic vasculitis&#46; &#40;A&#41; Prior to antibiotic therapy&#46; &#40;B&#41; After antibiotic therapy&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0025">Introduction</span><p id="par0005" class="elsevierStylePara elsevierViewall">Cutaneous vasculitides are inflammatory disorders affecting the wall of the vessels of the skin&#46; There can be a number of causes &#40;drug exposure&#44; infection&#44; neoplastic disease or systemic inflammatory disease&#41;&#44;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> and skin involvement may be its only manifestation&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Leukocytoclastic vasculitis is the most frequent cause of cutaneous vasculitis found in clinical practice&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> On occasion&#44; it can be associated with constitutional symptoms&#44; and thus be confused with systemic diseases and certain conditions like mycoplasma&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall"><span class="elsevierStyleItalic">Ureaplasma</span>&#44; which belongs to the same family as <span class="elsevierStyleItalic">Mycoplasma</span>&#44; is associated&#44; in adults&#44; with genital infections like nongonococcal urethritis&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a></p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0030">Clinical Observation</span><p id="par0020" class="elsevierStylePara elsevierViewall">We present the case of a 28-year-old man who had no significant previous medical history&#46; He presented at the emergency service with lesions in the skin on lower limbs and trunk that did not disappear when pressed by a finger&#46; The patient had no other systemic symptoms&#46; He did not have fever or signs of infection anywhere else&#44; except certain genital symptoms that were not well defined&#46; He denied the use of drugs&#44; sexual risk behavior and the consumption of any type of medication&#46; He had arthralgia but not arthritis and&#44; on the level of the skin&#44; he had flat&#44; erythematous&#44; nonpruritic lesions&#44; together with other bullous lesions &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; He underwent a skin biopsy which revealed leukocytoclastic vasculitis &#40;perivascular inflammatory infiltrate with predominance of neutrophils&#44; and nuclear dust&#44; fibrinoid degeneration and extravasated red blood cells&#59; subepidermal blisters with hemorrhagic and pustular content and focal epidermal necrosis&#41;&#46; The analytical study&#44; which involved acute-phase reactants&#44; complete blood count and biochemical and immunological data&#44; was normal&#46; A urine culture was negative&#44; as were serological tests for the hepatotropic viruses&#46; Colonies of <span class="elsevierStyleItalic">Ureaplasma urealyticum</span> were identified in the urethral exudate&#46; At admission&#44; treatment was begun with prednisone &#40;30<span class="elsevierStyleHsp" style=""></span>mg&#47;day&#41; and a nonsteroidal anti-inflammatory drug &#40;ibuprofen at 600<span class="elsevierStyleHsp" style=""></span>mg every 8<span class="elsevierStyleHsp" style=""></span>h&#41;&#46; This was followed by clinical improvement&#59; however&#44; it did not persist until antibiotic therapy was initiated with doxycycline&#44; in accordance with antibiogram indications for <span class="elsevierStyleItalic">Ureaplasma</span>&#46; Steroids were discontinued after 1 month and&#44; 6 months later&#44; the patient was asymptomatic without treatment&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0035">Discussion</span><p id="par0025" class="elsevierStylePara elsevierViewall">Leukocytoclastic vasculitis is the most common cutaneous vasculitis&#46; Although in 50&#37; of the cases&#44; the cause is usually idiopathic&#44; the histopathological diagnosis enabled by biopsy should be established as soon as possible to rule out other possibilities such as systemic&#44; neoplastic or infectious diseases&#46;<a class="elsevierStyleCrossRefs" href="#bib0030"><span class="elsevierStyleSup">1&#44;3&#8211;5</span></a> Nevertheless&#44; the term &#8220;leukocytoclastic vasculitis&#8221; does not specify the exact diagnosis&#46;<a class="elsevierStyleCrossRefs" href="#bib0045"><span class="elsevierStyleSup">4&#44;5</span></a> In sexually active patients&#44; we cannot forget that sexually transmitted diseases&#44; which include <span class="elsevierStyleItalic">Ureaplasma</span> infection&#44; can be asymptomatic and are related to a wide variety of pathological settings&#44; one of which is leukocytoclastic vasculitis&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">With regard to the treatment of leukocytoclastic vasculitis&#44; the first situation that should be treated is the triggering factor&#44;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a><span class="elsevierStyleItalic">Ureaplasma</span> infection in our patient&#44; leaving immunosuppressive therapy for cases that are refractory or in which the involvement is severe&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a></p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0040">Conclusions</span><p id="par0035" class="elsevierStylePara elsevierViewall">There are many factors that can be associated with leukocytoclastic vasculitis as triggers of the disease&#46;</p><p id="par0040" class="elsevierStylePara elsevierViewall">Infections are a frequent cause of cutaneous vasculitis and joint involvement&#46;</p><p id="par0045" class="elsevierStylePara elsevierViewall">There are infections in which the symptoms are less evident that should be taken into account in the examination of our patients&#44; because there may be a causal relationship&#46;</p></span><span id="sec0025" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0045">Ethical Disclosures</span><span id="sec0030" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0050">Protection of human and animal subjects</span><p id="par0050" class="elsevierStylePara elsevierViewall">The authors declare that no experiments were performed on humans or animals for this study&#46;</p></span><span id="sec0035" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0055">Confidentiality of data</span><p id="par0055" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span><span id="sec0040" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0060">Right to privacy and informed consent</span><p id="par0060" class="elsevierStylePara elsevierViewall">The authors declare that no patient data appear in this article&#46;</p></span></span><span id="sec0045" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0065">Conflicts of Interest</span><p id="par0065" class="elsevierStylePara elsevierViewall">The authors declare they have no conflicts of interest&#46;</p></span></span>"
    "textoCompletoSecciones" => array:1 [
      "secciones" => array:11 [
        0 => array:3 [
          "identificador" => "xres884942"
          "titulo" => "Abstract"
          "secciones" => array:1 [
            0 => array:1 [
              "identificador" => "abst0005"
            ]
          ]
        ]
        1 => array:2 [
          "identificador" => "xpalclavsec871142"
          "titulo" => "Keywords"
        ]
        2 => array:3 [
          "identificador" => "xres884943"
          "titulo" => "Resumen"
          "secciones" => array:1 [
            0 => array:1 [
              "identificador" => "abst0010"
            ]
          ]
        ]
        3 => array:2 [
          "identificador" => "xpalclavsec871141"
          "titulo" => "Palabras clave"
        ]
        4 => array:2 [
          "identificador" => "sec0005"
          "titulo" => "Introduction"
        ]
        5 => array:2 [
          "identificador" => "sec0010"
          "titulo" => "Clinical Observation"
        ]
        6 => array:2 [
          "identificador" => "sec0015"
          "titulo" => "Discussion"
        ]
        7 => array:2 [
          "identificador" => "sec0020"
          "titulo" => "Conclusions"
        ]
        8 => array:3 [
          "identificador" => "sec0025"
          "titulo" => "Ethical Disclosures"
          "secciones" => array:3 [
            0 => array:2 [
              "identificador" => "sec0030"
              "titulo" => "Protection of human and animal subjects"
            ]
            1 => array:2 [
              "identificador" => "sec0035"
              "titulo" => "Confidentiality of data"
            ]
            2 => array:2 [
              "identificador" => "sec0040"
              "titulo" => "Right to privacy and informed consent"
            ]
          ]
        ]
        9 => array:2 [
          "identificador" => "sec0045"
          "titulo" => "Conflicts of Interest"
        ]
        10 => array:1 [
          "titulo" => "References"
        ]
      ]
    ]
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "fechaRecibido" => "2016-01-25"
    "fechaAceptado" => "2016-04-08"
    "PalabrasClave" => array:2 [
      "en" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Keywords"
          "identificador" => "xpalclavsec871142"
          "palabras" => array:4 [
            0 => "Cutaneous vasculitis"
            1 => "Infection"
            2 => "<span class="elsevierStyleItalic">Ureaplasma urealyticum</span>"
            3 => "Leukocytoclastic vasculitis"
          ]
        ]
      ]
      "es" => array:1 [
        0 => array:4 [
          "clase" => "keyword"
          "titulo" => "Palabras clave"
          "identificador" => "xpalclavsec871141"
          "palabras" => array:4 [
            0 => "Vasculitis cut&#225;nea"
            1 => "Infecci&#243;n"
            2 => "<span class="elsevierStyleItalic">Ureaplasma urealyticum</span>"
            3 => "Vasculitis leucocitocl&#225;stica"
          ]
        ]
      ]
    ]
    "tieneResumen" => true
    "resumen" => array:2 [
      "en" => array:2 [
        "titulo" => "Abstract"
        "resumen" => "<span id="abst0005" class="elsevierStyleSection elsevierViewall"><p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Leukocytoclastic vasculitis is the most common cause of cutaneous vasculitis in clinical practice&#46; Its causes are various&#44; among which are certain infections&#46; We report the case of a man &#40;28 years old&#41; who debuted with vasculitic lesions in inferior members compatibles leukocytoclastic vasculitis on pathology&#46; The study of causation is the presence of a positive urethral discharge to <span class="elsevierStyleItalic">Ureaplasma urealyticum</span>&#44; dramatically improving lesions after treatment thereof&#46;</p></span>"
      ]
      "es" => array:2 [
        "titulo" => "Resumen"
        "resumen" => "<span id="abst0010" class="elsevierStyleSection elsevierViewall"><p id="spar0010" class="elsevierStyleSimplePara elsevierViewall">La vasculitis leucocitocl&#225;stica es la causa m&#225;s frecuente de vasculitis cut&#225;nea en la pr&#225;ctica cl&#237;nica&#46; Sus causas son diversas&#44; entre las que se encuentran ciertas infecciones&#46;</p><p id="spar0015" class="elsevierStyleSimplePara elsevierViewall">Presentamos el caso de un var&#243;n de 28 a&#241;os que debuta con lesiones vascul&#237;ticas en miembros inferiores&#44; compatibles con una vasculitis leucocitocl&#225;stica en la anatom&#237;a patol&#243;gica&#46; En el estudio de causalidad se encuentra la presencia de un exudado uretral positivo a <span class="elsevierStyleItalic">Ureaplasma urealyticum</span>&#44; mejorando dr&#225;sticamente las lesiones tras el tratamiento del mismo&#46;</p></span>"
      ]
    ]
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; Moreno Mart&#237;nez MJ&#44; Palma S&#225;nchez D&#44; Pe&#241;as Mart&#237;nez E&#44; Haro Mart&#237;nez A&#44; Mayor Gonz&#225;lez M&#46; Vasculitis leucocitocl&#225;stica e infecci&#243;n&#46; A prop&#243;sito de un caso&#46; Reumatol Clin&#46; 2017&#59;13&#58;297&#8211;298&#46;</p>"
      ]
    ]
    "multimedia" => array:1 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 673
            "Ancho" => 1500
            "Tamanyo" => 100367
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0020" class="elsevierStyleSimplePara elsevierViewall">Vesiculobullous form of cutaneous leukocytoclastic vasculitis&#46; &#40;A&#41; Prior to antibiotic therapy&#46; &#40;B&#41; After antibiotic therapy&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0005"
          "bibliografiaReferencia" => array:5 [
            0 => array:3 [
              "identificador" => "bib0030"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Vasculitis cut&#225;neas"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46; Pulido-P&#233;rez"
                            1 => "J&#46;A&#46; Avil&#233;s-Izquierdo"
                            2 => "R&#46; Su&#225;rez-Fern&#225;ndez"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.ad.2011.06.001"
                      "Revista" => array:6 [
                        "tituloSerie" => "Actas Dermosifiliogr"
                        "fecha" => "2012"
                        "volumen" => "103"
                        "paginaInicial" => "179"
                        "paginaFinal" => "191"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/21839977"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:3 [
                  "comentario" => "Available from&#58; <span class="elsevierStyleInterRef" id="intr0010" href="http://www.ine.gov.ar/documentos/publicaciones/028.pdf">http&#58;&#47;&#47;www&#46;ine&#46;gov&#46;ar&#47;documentos&#47;publicaciones&#47;028&#46;pdf</span> &#91;accessed 18&#46;11&#46;15&#93;"
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Infecciones de transmisi&#243;n sexual por <span class="elsevierStyleItalic">Ureaplasma urealyticum</span> y <span class="elsevierStyleItalic">Mycoplasma hominis</span>"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:4 [
                            0 => "C&#46;M&#46; Zotta"
                            1 => "D&#46; G&#243;mez"
                            2 => "S&#46; Lavay&#233;n"
                            3 => "M&#46;G&#46; Galeano"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "SaludiCiencia"
                        "fecha" => "2013"
                        "volumen" => "20"
                        "paginaInicial" => "37"
                        "paginaFinal" => "40"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "A practical approach to the diagnosis&#44; evaluation&#44; and management of cutaneous small-vessel vasculitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "M&#46;R&#46; Goeser"
                            1 => "V&#46; Laniosz"
                            2 => "D&#46;A&#46; Wetter"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s40257-014-0076-6"
                      "Revista" => array:6 [
                        "tituloSerie" => "Am J Clin Dermatol"
                        "fecha" => "2014"
                        "volumen" => "15"
                        "paginaInicial" => "299"
                        "paginaFinal" => "306"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/24756249"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Cutaneous manifestations of vasculitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "L&#46; Xu"
                            1 => "E&#46; Esparza"
                            2 => "M&#46; Anadkat"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.semarthrit.2008.01.007"
                      "Revista" => array:6 [
                        "tituloSerie" => "Semin Arthritis Rheum"
                        "fecha" => "2009"
                        "volumen" => "38"
                        "paginaInicial" => "348"
                        "paginaFinal" => "360"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18355896"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Skin involvement in cutaneous and systemic vasculitis"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "A&#46;V&#46; Marzano"
                            1 => "P&#46; Vezzoli"
                            2 => "E&#46; Berti"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/j.autrev.2012.08.005"
                      "Revista" => array:7 [
                        "tituloSerie" => "Autoimmun Rev"
                        "fecha" => "2013"
                        "volumen" => "12"
                        "paginaInicial" => "467"
                        "paginaFinal" => "476"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/22959234"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0140673613616475"
                          "estado" => "S300"
                          "issn" => "01406736"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735743/0000001300000005/v1_201708230012/S2173574317300394/v1_201708230012/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "67860"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Case reports"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735743/0000001300000005/v1_201708230012/S2173574317300394/v1_201708230012/en/main.pdf?idApp=UINPBA00004M&text.app=https://reumatologiaclinica.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574317300394?idApp=UINPBA00004M"
]
Article information
ISSN: 21735743
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 November 12 17 29
2024 October 87 57 144
2024 September 131 49 180
2024 August 132 63 195
2024 July 114 45 159
2024 June 126 43 169
2024 May 149 55 204
2024 April 123 35 158
2024 March 111 41 152
2024 February 108 30 138
2024 January 124 28 152
2023 December 85 26 111
2023 November 120 14 134
2023 October 117 30 147
2023 September 149 38 187
2023 August 124 20 144
2023 July 144 33 177
2023 June 141 25 166
2023 May 119 22 141
2023 April 90 19 109
2023 March 120 52 172
2023 February 129 31 160
2023 January 170 17 187
2022 December 113 40 153
2022 November 157 26 183
2022 October 128 37 165
2022 September 112 40 152
2022 August 149 38 187
2022 July 93 49 142
2022 June 85 34 119
2022 May 130 51 181
2022 April 152 60 212
2022 March 141 51 192
2022 February 167 28 195
2022 January 142 48 190
2021 December 133 56 189
2021 November 90 40 130
2021 October 64 55 119
2021 September 77 40 117
2021 August 64 36 100
2021 July 62 35 97
2021 June 89 35 124
2021 May 105 42 147
2021 April 317 81 398
2021 March 150 38 188
2021 February 78 17 95
2021 January 95 31 126
2020 December 79 18 97
2020 November 70 29 99
2020 October 50 23 73
2020 September 82 28 110
2020 August 54 20 74
2020 July 39 12 51
2020 June 66 29 95
2020 May 52 17 69
2020 April 40 25 65
2020 March 12 5 17
2020 February 1 0 1
2019 February 1 0 1
2018 May 5 0 5
2018 April 70 7 77
2018 March 103 10 113
2018 February 44 5 49
2018 January 47 7 54
2017 December 43 12 55
2017 November 50 18 68
2017 October 73 33 106
2017 September 95 31 126
2017 August 37 21 58
2017 July 13 10 23
2017 June 21 13 34
2017 May 12 11 23
2017 April 9 13 22
2017 March 1 1 2
Show all

Follow this link to access the full text of the article

Idiomas
Reumatología Clínica (English Edition)
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?