array:24 [
  "pii" => "S2173574318301709"
  "issn" => "21735743"
  "doi" => "10.1016/j.reumae.2018.12.002"
  "estado" => "S300"
  "fechaPublicacion" => "2019-09-01"
  "aid" => "1141"
  "copyright" => "Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología"
  "copyrightAnyo" => "2017"
  "documento" => "simple-article"
  "crossmark" => 1
  "subdocumento" => "cor"
  "cita" => "Reumatol Clin. 2019;15:e74"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 1
    "HTML" => 1
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S1699258X17302644"
      "issn" => "1699258X"
      "doi" => "10.1016/j.reuma.2017.10.005"
      "estado" => "S300"
      "fechaPublicacion" => "2019-09-01"
      "aid" => "1141"
      "copyright" => "Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología"
      "documento" => "simple-article"
      "crossmark" => 1
      "subdocumento" => "cor"
      "cita" => "Reumatol Clin. 2019;15:e74"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 605
        "formatos" => array:3 [
          "EPUB" => 55
          "HTML" => 248
          "PDF" => 302
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Carta al Editor</span>"
        "titulo" => "Evaluaci&#243;n de un paciente con trastornos de la articulaci&#243;n temporomandibular en la enfermedad &#243;sea de Paget"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:1 [
            "paginaInicial" => "e74"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Evaluation of a Patient With Temporomandibular Joint Disorders in Paget&#39;s Disease of Bone"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 625
                "Ancho" => 750
                "Tamanyo" => 30080
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">TAC en la que se aprecian deformidad condilar con osteoesclerosis&#44; aplanamiento y osteofitos&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Jos&#233; Dario S&#225;nchez L&#243;pez, Paolo Cariati, Miguel Angel P&#233;rez de Perceval Tara"
            "autores" => array:3 [
              0 => array:2 [
                "nombre" => "Jos&#233; Dario"
                "apellidos" => "S&#225;nchez L&#243;pez"
              ]
              1 => array:2 [
                "nombre" => "Paolo"
                "apellidos" => "Cariati"
              ]
              2 => array:2 [
                "nombre" => "Miguel Angel"
                "apellidos" => "P&#233;rez de Perceval Tara"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2173574318301709"
          "doi" => "10.1016/j.reumae.2018.12.002"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => false
            "ES2" => false
            "LATM" => false
          ]
          "gratuito" => false
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574318301709?idApp=UINPBA00004M"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X17302644?idApp=UINPBA00004M"
      "url" => "/1699258X/0000001500000005/v1_201910230648/S1699258X17302644/v1_201910230648/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2173574318301692"
    "issn" => "21735743"
    "doi" => "10.1016/j.reumae.2018.12.001"
    "estado" => "S300"
    "fechaPublicacion" => "2019-09-01"
    "aid" => "1138"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Reumatolog&#237;a y Colegio Mexicano de Reumatolog&#237;a"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "cor"
    "cita" => "Reumatol Clin. 2019;15:e75-e77"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2
      "HTML" => 2
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "Study of Apoptosis and Intercellular Adhesion in Oral Mucosa of Patients With Osteonecrosis Induced by Biphosphonates"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "e75"
          "paginaFinal" => "e77"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Estudio de apoptosis y adhesi&#243;n intercelular en mucosa oral de pacientes con osteonecrosis inducida por bifosfonatos"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1340
              "Ancho" => 1500
              "Tamanyo" => 515122
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Immunohistochemical apoptosis profile of oral mucosa in patients with osteonecrosis induced by BP&#46; &#40;A&#41; Microphotographs &#40;40&#215;&#41; showing nuclear expression of Bax in epithelium&#44; mainly in the basal and parabasal layer&#46; &#40;B&#41; Microphotographs &#40;40&#215;&#41; showing nuclear expression of Bax in spiny epithelium strata&#46; &#40;C and D&#41; Absence of the expression of Bcl-2 &#40;C&#41; and survivin &#40;D&#41; in oral mucosa epithelium&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Mariana Villarroel-Dorrego, Mar&#237;a Elena Romero, Orlando Reyes, Vanesa Pereira-Prado, Ronell Bologna-Molina"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "Mariana"
              "apellidos" => "Villarroel-Dorrego"
            ]
            1 => array:2 [
              "nombre" => "Mar&#237;a Elena"
              "apellidos" => "Romero"
            ]
            2 => array:2 [
              "nombre" => "Orlando"
              "apellidos" => "Reyes"
            ]
            3 => array:2 [
              "nombre" => "Vanesa"
              "apellidos" => "Pereira-Prado"
            ]
            4 => array:2 [
              "nombre" => "Ronell"
              "apellidos" => "Bologna-Molina"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S1699258X1730253X"
        "doi" => "10.1016/j.reuma.2017.10.002"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X1730253X?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574318301692?idApp=UINPBA00004M"
    "url" => "/21735743/0000001500000005/v1_201910260908/S2173574318301692/v1_201910260908/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173574319301054"
    "issn" => "21735743"
    "doi" => "10.1016/j.reumae.2017.10.005"
    "estado" => "S300"
    "fechaPublicacion" => "2019-09-01"
    "aid" => "1144"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Reumatolog&#237;a y Colegio Mexicano de Reumatolog&#237;a"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "cor"
    "cita" => "Reumatol Clin. 2019;15:e72-e73"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 1
      "HTML" => 1
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "Linear atrophy and hypopigmentation after intralesional corticosteroid injection"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "e72"
          "paginaFinal" => "e73"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Atrofia e hipopigmentaci&#243;n lineal cut&#225;nea por inyecci&#243;n intraarticular de corticosteroide"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1180
              "Ancho" => 1400
              "Tamanyo" => 214991
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#8211;C&#41; Hypopigmented atrophic patch on the elbow&#44; with linear extension along the upper arm&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Ignacio Hern&#225;ndez Arag&#252;&#233;s, C&#46; Ana Villanueva &#193;lvarez-Santullano, Ricardo Su&#225;rez Fern&#225;ndez, Ana Pulido P&#233;rez"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Ignacio"
              "apellidos" => "Hern&#225;ndez Arag&#252;&#233;s"
            ]
            1 => array:2 [
              "nombre" => "C&#46; Ana"
              "apellidos" => "Villanueva &#193;lvarez-Santullano"
            ]
            2 => array:2 [
              "nombre" => "Ricardo"
              "apellidos" => "Su&#225;rez Fern&#225;ndez"
            ]
            3 => array:2 [
              "nombre" => "Ana"
              "apellidos" => "Pulido P&#233;rez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S1699258X1730267X"
        "doi" => "10.1016/j.reuma.2017.10.008"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X1730267X?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574319301054?idApp=UINPBA00004M"
    "url" => "/21735743/0000001500000005/v1_201910260908/S2173574319301054/v1_201910260908/en/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
    "titulo" => "Evaluation of a Patient With Temporomandibular Joint Disorders in Paget&#39;s Disease of Bone"
    "tieneTextoCompleto" => true
    "saludo" => "Dear Editor&#44;"
    "paginas" => array:1 [
      0 => array:1 [
        "paginaInicial" => "e74"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Jos&#233; Dario S&#225;nchez L&#243;pez, Paolo Cariati, Miguel Angel P&#233;rez de Perceval Tara"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "Jos&#233; Dario"
            "apellidos" => "S&#225;nchez L&#243;pez"
            "email" => array:1 [
              0 => "josed.sanchez.sspa@juntadeandalucia.es"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "&#42;"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "Paolo"
            "apellidos" => "Cariati"
          ]
          2 => array:2 [
            "nombre" => "Miguel Angel"
            "apellidos" => "P&#233;rez de Perceval Tara"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Cirug&#237;a Oral y Maxilofacial&#44; Hospital Universitario Virgen de las Nieves&#44; Granada&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Evaluaci&#243;n de un paciente con trastornos de la articulaci&#243;n temporomandibular en la enfermedad &#243;sea de Paget"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 625
            "Ancho" => 750
            "Tamanyo" => 30080
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">CT scan showing condylar deformity with osteosclerosis&#44; flattening and osteophytes&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Paget&#39;s disease of bone &#40;PDB&#41; is a chronic process characterised by an increase in bone remodelling&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> Its clinical presentation varies and may consist of asymptomatic cases detected by an increase in serum levels of alkaline phosphatase &#40;AP&#41; or coincidental radiological findings&#44; or even bone pain and bone deformity&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">First line treatment is aimed at reducing pain &#40;NSAIDS&#44; paracetamol&#44; COX-2 inhibitors&#41; and later to reducing the speed of bone turnover &#40;calcitonin and bisphosphonates &#91;BP&#93;&#46;&#41;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">3</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">The aim of this clinical case is to show an unusual presentation in TMJ within the context of a PDB&#44; and also to show what treatment may be followed&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">We present the case of a 72-year-old patient who was diagnosed with a monostotic variant of PDB &#40;affecting the ulna&#41; of 5-year duration&#44; which was initially treated with analgesics &#40;NSAIDS&#44; paracetamol&#44; COX-2 inhibitors&#41; and later with oral alendronate at a dose of 40<span class="elsevierStyleHsp" style=""></span>mg quarterly together with vitamin D &#40;400<span class="elsevierStyleHsp" style=""></span>U&#41; and Calcium &#40;1&#46;5<span class="elsevierStyleHsp" style=""></span>g&#41; supplements&#46; The patient was referred to our department suffering from pain &#40;VAS<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>7&#47;10&#41; in the right temporomandibular Joint &#40;TMJ&#41; and a reduction of oral opening &#40;&#60;2&#46;5<span class="elsevierStyleHsp" style=""></span>cm&#41;&#46; The examination was completed with computerised axial tomography &#40;CAT&#41; which revealed condylar deformity with osteosclerosis and osteophytes &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; The diagnosis made was arthropathy of the TMJ and was initially treated with a jaw release splint&#44; rehabilitation exercises&#44; analgesic treatment and muscle relaxants&#46; Following periodic three-monthly check-ups after a year of treatment a reduction in pain was noted &#40;VAS&#58; 3&#47;10&#41; and an increase in joint function with oral opening above 3<span class="elsevierStyleHsp" style=""></span>cm&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">Involvement of the jawbones and specifically of the TMJ in PDB is a rare occurrence&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">4</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Despite not verifying jawbone involvement&#44; and without being able to rule out other causes &#40;osteoarthritis&#44; arthritis&#41;&#44; due to the absence of previous events&#44; this case was suggestive of an isolated involvement of the TMJ provoked by continuous stress to which the articular condyles are subjected as a consequence of mastication&#44; leading to degenerative phenomena with episodes of bone remodelling&#46; However&#44; confirmation of this hypothesis would require the undertaking of more specific tests &#40;bone scintigraphy&#41;&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Clinical signs of improvement globally appreciated corroborate the current trend<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">5&#44;6</span></a> that treatment with second and third generation BPs &#40;pamidronate&#44; alendronate&#44; risedronate&#44; zoledronate&#41; are more effective than calcitonin and etidronate for serum and degenerative disease control&#46;</p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; S&#225;nchez L&#243;pez JD&#44; Cariati P&#44; P&#233;rez de Perceval Tara MA&#46; Evaluaci&#243;n de un paciente con trastornos de la articulaci&#243;n temporomandibular en la enfermedad &#243;sea de Paget&#46; Reumatol Clin&#46; 2019&#59;15&#58;e74&#46;</p>"
      ]
    ]
    "multimedia" => array:1 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 625
            "Ancho" => 750
            "Tamanyo" => 30080
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">CT scan showing condylar deformity with osteosclerosis&#44; flattening and osteophytes&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:6 [
            0 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pathogenesis and management of Paget&#39;s disease of bone"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;H&#46; Ralston"
                            1 => "A&#46;L&#46; Langston"
                            2 => "I&#46;R&#46; Reid"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S0140-6736(08)61035-1"
                      "Revista" => array:7 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "2008"
                        "volumen" => "372"
                        "paginaInicial" => "155"
                        "paginaFinal" => "163"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18620951"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0022202X15000512"
                          "estado" => "S300"
                          "issn" => "0022202X"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Paget&#39;s disease of bone"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46;P&#46; Whyte"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJMcp060278"
                      "Revista" => array:7 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "2006"
                        "volumen" => "355"
                        "paginaInicial" => "593"
                        "paginaFinal" => "600"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16899779"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0022202X17313076"
                          "estado" => "S300"
                          "issn" => "0022202X"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical and genetic advances in Pagets disease of bone&#58; a review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "N&#46; Alonso"
                            1 => "I&#46; Calero-Paniagua"
                            2 => "J&#46; del Pino-Montes"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s12018-016-9226-0"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Rev Bone Miner Metab"
                        "fecha" => "2017"
                        "volumen" => "15"
                        "paginaInicial" => "37"
                        "paginaFinal" => "48"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28255281"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Discopathy and osteoarthritis of temporomandibular joint in a patient with Paget disease and osteoporosis&#46; A case report"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "T&#46; Badel"
                            1 => "D&#46; Podoreski"
                            2 => "S&#46; Kraljevic"
                            3 => "J&#46; Keros"
                            4 => "L&#46; Krapac"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Bone"
                        "fecha" => "2009"
                        "volumen" => "44"
                        "paginaInicial" => "339"
                        "paginaFinal" => "350"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Paget&#39;s disease of bone&#58; an endocrine society clinical practice guideline"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46;R&#46; Singer"
                            1 => "H&#46;G&#46; Bone 3rd"
                            2 => "D&#46;J&#46; Hosking"
                            3 => "K&#46;W&#46; Lyles"
                            4 => "M&#46;H&#46; Murad"
                            5 => "I&#46;R&#46; Reid"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1210/jc.2014-2910"
                      "Revista" => array:7 [
                        "tituloSerie" => "J Clin Endocrinol Metab"
                        "fecha" => "2014"
                        "volumen" => "99"
                        "paginaInicial" => "4408"
                        "paginaFinal" => "4422"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25406796"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0022202X15000664"
                          "estado" => "S300"
                          "issn" => "0022202X"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparison of different intravenous bisphosphonate regimens for Paget&#39;s disease of bone"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "D&#46;L&#46; Merlotti"
                            1 => "G&#46; Gennari"
                            2 => "F&#46; Martini"
                            3 => "V&#46; Valleggi"
                            4 => "A&#46; de Paola"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1359/jbmr.070704"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Bone Miner Res"
                        "fecha" => "2007"
                        "volumen" => "22"
                        "paginaInicial" => "1510"
                        "paginaFinal" => "1517"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17605632"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735743/0000001500000005/v1_201910260908/S2173574318301709/v1_201910260908/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "8400"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Letters to the Editor"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735743/0000001500000005/v1_201910260908/S2173574318301709/v1_201910260908/en/main.pdf?idApp=UINPBA00004M&text.app=https://reumatologiaclinica.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574318301709?idApp=UINPBA00004M"
]
Share
Journal Information

Statistics

Follow this link to access the full text of the article

Letter to the Editor
Evaluation of a Patient With Temporomandibular Joint Disorders in Paget's Disease of Bone
Evaluación de un paciente con trastornos de la articulación temporomandibular en la enfermedad ósea de Paget
José Dario Sánchez López
Corresponding author
, Paolo Cariati, Miguel Angel Pérez de Perceval Tara
Servicio de Cirugía Oral y Maxilofacial, Hospital Universitario Virgen de las Nieves, Granada, Spain
Read
3911
Times
was read the article
1530
Total PDF
2381
Total HTML
Share statistics
 array:24 [
  "pii" => "S2173574318301709"
  "issn" => "21735743"
  "doi" => "10.1016/j.reumae.2018.12.002"
  "estado" => "S300"
  "fechaPublicacion" => "2019-09-01"
  "aid" => "1141"
  "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Reumatolog&#237;a y Colegio Mexicano de Reumatolog&#237;a"
  "copyrightAnyo" => "2017"
  "documento" => "simple-article"
  "crossmark" => 1
  "subdocumento" => "cor"
  "cita" => "Reumatol Clin. 2019;15:e74"
  "abierto" => array:3 [
    "ES" => false
    "ES2" => false
    "LATM" => false
  ]
  "gratuito" => false
  "lecturas" => array:2 [
    "total" => 1
    "HTML" => 1
  ]
  "Traduccion" => array:1 [
    "es" => array:19 [
      "pii" => "S1699258X17302644"
      "issn" => "1699258X"
      "doi" => "10.1016/j.reuma.2017.10.005"
      "estado" => "S300"
      "fechaPublicacion" => "2019-09-01"
      "aid" => "1141"
      "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Reumatolog&#237;a y Colegio Mexicano de Reumatolog&#237;a"
      "documento" => "simple-article"
      "crossmark" => 1
      "subdocumento" => "cor"
      "cita" => "Reumatol Clin. 2019;15:e74"
      "abierto" => array:3 [
        "ES" => true
        "ES2" => true
        "LATM" => true
      ]
      "gratuito" => true
      "lecturas" => array:2 [
        "total" => 605
        "formatos" => array:3 [
          "EPUB" => 55
          "HTML" => 248
          "PDF" => 302
        ]
      ]
      "es" => array:11 [
        "idiomaDefecto" => true
        "cabecera" => "<span class="elsevierStyleTextfn">Carta al Editor</span>"
        "titulo" => "Evaluaci&#243;n de un paciente con trastornos de la articulaci&#243;n temporomandibular en la enfermedad &#243;sea de Paget"
        "tienePdf" => "es"
        "tieneTextoCompleto" => "es"
        "paginas" => array:1 [
          0 => array:1 [
            "paginaInicial" => "e74"
          ]
        ]
        "titulosAlternativos" => array:1 [
          "en" => array:1 [
            "titulo" => "Evaluation of a Patient With Temporomandibular Joint Disorders in Paget&#39;s Disease of Bone"
          ]
        ]
        "contieneTextoCompleto" => array:1 [
          "es" => true
        ]
        "contienePdf" => array:1 [
          "es" => true
        ]
        "resumenGrafico" => array:2 [
          "original" => 0
          "multimedia" => array:7 [
            "identificador" => "fig0005"
            "etiqueta" => "Figura 1"
            "tipo" => "MULTIMEDIAFIGURA"
            "mostrarFloat" => true
            "mostrarDisplay" => false
            "figura" => array:1 [
              0 => array:4 [
                "imagen" => "gr1.jpeg"
                "Alto" => 625
                "Ancho" => 750
                "Tamanyo" => 30080
              ]
            ]
            "descripcion" => array:1 [
              "es" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">TAC en la que se aprecian deformidad condilar con osteoesclerosis&#44; aplanamiento y osteofitos&#46;</p>"
            ]
          ]
        ]
        "autores" => array:1 [
          0 => array:2 [
            "autoresLista" => "Jos&#233; Dario S&#225;nchez L&#243;pez, Paolo Cariati, Miguel Angel P&#233;rez de Perceval Tara"
            "autores" => array:3 [
              0 => array:2 [
                "nombre" => "Jos&#233; Dario"
                "apellidos" => "S&#225;nchez L&#243;pez"
              ]
              1 => array:2 [
                "nombre" => "Paolo"
                "apellidos" => "Cariati"
              ]
              2 => array:2 [
                "nombre" => "Miguel Angel"
                "apellidos" => "P&#233;rez de Perceval Tara"
              ]
            ]
          ]
        ]
      ]
      "idiomaDefecto" => "es"
      "Traduccion" => array:1 [
        "en" => array:9 [
          "pii" => "S2173574318301709"
          "doi" => "10.1016/j.reumae.2018.12.002"
          "estado" => "S300"
          "subdocumento" => ""
          "abierto" => array:3 [
            "ES" => false
            "ES2" => false
            "LATM" => false
          ]
          "gratuito" => false
          "lecturas" => array:1 [
            "total" => 0
          ]
          "idiomaDefecto" => "en"
          "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574318301709?idApp=UINPBA00004M"
        ]
      ]
      "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X17302644?idApp=UINPBA00004M"
      "url" => "/1699258X/0000001500000005/v1_201910230648/S1699258X17302644/v1_201910230648/es/main.assets"
    ]
  ]
  "itemSiguiente" => array:19 [
    "pii" => "S2173574318301692"
    "issn" => "21735743"
    "doi" => "10.1016/j.reumae.2018.12.001"
    "estado" => "S300"
    "fechaPublicacion" => "2019-09-01"
    "aid" => "1138"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Reumatolog&#237;a y Colegio Mexicano de Reumatolog&#237;a"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "cor"
    "cita" => "Reumatol Clin. 2019;15:e75-e77"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 2
      "HTML" => 2
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "Study of Apoptosis and Intercellular Adhesion in Oral Mucosa of Patients With Osteonecrosis Induced by Biphosphonates"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "e75"
          "paginaFinal" => "e77"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Estudio de apoptosis y adhesi&#243;n intercelular en mucosa oral de pacientes con osteonecrosis inducida por bifosfonatos"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1340
              "Ancho" => 1500
              "Tamanyo" => 515122
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">Immunohistochemical apoptosis profile of oral mucosa in patients with osteonecrosis induced by BP&#46; &#40;A&#41; Microphotographs &#40;40&#215;&#41; showing nuclear expression of Bax in epithelium&#44; mainly in the basal and parabasal layer&#46; &#40;B&#41; Microphotographs &#40;40&#215;&#41; showing nuclear expression of Bax in spiny epithelium strata&#46; &#40;C and D&#41; Absence of the expression of Bcl-2 &#40;C&#41; and survivin &#40;D&#41; in oral mucosa epithelium&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Mariana Villarroel-Dorrego, Mar&#237;a Elena Romero, Orlando Reyes, Vanesa Pereira-Prado, Ronell Bologna-Molina"
          "autores" => array:5 [
            0 => array:2 [
              "nombre" => "Mariana"
              "apellidos" => "Villarroel-Dorrego"
            ]
            1 => array:2 [
              "nombre" => "Mar&#237;a Elena"
              "apellidos" => "Romero"
            ]
            2 => array:2 [
              "nombre" => "Orlando"
              "apellidos" => "Reyes"
            ]
            3 => array:2 [
              "nombre" => "Vanesa"
              "apellidos" => "Pereira-Prado"
            ]
            4 => array:2 [
              "nombre" => "Ronell"
              "apellidos" => "Bologna-Molina"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S1699258X1730253X"
        "doi" => "10.1016/j.reuma.2017.10.002"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X1730253X?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574318301692?idApp=UINPBA00004M"
    "url" => "/21735743/0000001500000005/v1_201910260908/S2173574318301692/v1_201910260908/en/main.assets"
  ]
  "itemAnterior" => array:19 [
    "pii" => "S2173574319301054"
    "issn" => "21735743"
    "doi" => "10.1016/j.reumae.2017.10.005"
    "estado" => "S300"
    "fechaPublicacion" => "2019-09-01"
    "aid" => "1144"
    "copyright" => "Elsevier Espa&#241;a&#44; S&#46;L&#46;U&#46; and Sociedad Espa&#241;ola de Reumatolog&#237;a y Colegio Mexicano de Reumatolog&#237;a"
    "documento" => "simple-article"
    "crossmark" => 1
    "subdocumento" => "cor"
    "cita" => "Reumatol Clin. 2019;15:e72-e73"
    "abierto" => array:3 [
      "ES" => false
      "ES2" => false
      "LATM" => false
    ]
    "gratuito" => false
    "lecturas" => array:2 [
      "total" => 1
      "HTML" => 1
    ]
    "en" => array:11 [
      "idiomaDefecto" => true
      "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
      "titulo" => "Linear atrophy and hypopigmentation after intralesional corticosteroid injection"
      "tienePdf" => "en"
      "tieneTextoCompleto" => "en"
      "paginas" => array:1 [
        0 => array:2 [
          "paginaInicial" => "e72"
          "paginaFinal" => "e73"
        ]
      ]
      "titulosAlternativos" => array:1 [
        "es" => array:1 [
          "titulo" => "Atrofia e hipopigmentaci&#243;n lineal cut&#225;nea por inyecci&#243;n intraarticular de corticosteroide"
        ]
      ]
      "contieneTextoCompleto" => array:1 [
        "en" => true
      ]
      "contienePdf" => array:1 [
        "en" => true
      ]
      "resumenGrafico" => array:2 [
        "original" => 0
        "multimedia" => array:7 [
          "identificador" => "fig0005"
          "etiqueta" => "Fig&#46; 1"
          "tipo" => "MULTIMEDIAFIGURA"
          "mostrarFloat" => true
          "mostrarDisplay" => false
          "figura" => array:1 [
            0 => array:4 [
              "imagen" => "gr1.jpeg"
              "Alto" => 1180
              "Ancho" => 1400
              "Tamanyo" => 214991
            ]
          ]
          "descripcion" => array:1 [
            "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">&#40;A&#8211;C&#41; Hypopigmented atrophic patch on the elbow&#44; with linear extension along the upper arm&#46;</p>"
          ]
        ]
      ]
      "autores" => array:1 [
        0 => array:2 [
          "autoresLista" => "Ignacio Hern&#225;ndez Arag&#252;&#233;s, C&#46; Ana Villanueva &#193;lvarez-Santullano, Ricardo Su&#225;rez Fern&#225;ndez, Ana Pulido P&#233;rez"
          "autores" => array:4 [
            0 => array:2 [
              "nombre" => "Ignacio"
              "apellidos" => "Hern&#225;ndez Arag&#252;&#233;s"
            ]
            1 => array:2 [
              "nombre" => "C&#46; Ana"
              "apellidos" => "Villanueva &#193;lvarez-Santullano"
            ]
            2 => array:2 [
              "nombre" => "Ricardo"
              "apellidos" => "Su&#225;rez Fern&#225;ndez"
            ]
            3 => array:2 [
              "nombre" => "Ana"
              "apellidos" => "Pulido P&#233;rez"
            ]
          ]
        ]
      ]
    ]
    "idiomaDefecto" => "en"
    "Traduccion" => array:1 [
      "es" => array:9 [
        "pii" => "S1699258X1730267X"
        "doi" => "10.1016/j.reuma.2017.10.008"
        "estado" => "S300"
        "subdocumento" => ""
        "abierto" => array:3 [
          "ES" => true
          "ES2" => true
          "LATM" => true
        ]
        "gratuito" => true
        "lecturas" => array:1 [
          "total" => 0
        ]
        "idiomaDefecto" => "es"
        "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S1699258X1730267X?idApp=UINPBA00004M"
      ]
    ]
    "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574319301054?idApp=UINPBA00004M"
    "url" => "/21735743/0000001500000005/v1_201910260908/S2173574319301054/v1_201910260908/en/main.assets"
  ]
  "en" => array:15 [
    "idiomaDefecto" => true
    "cabecera" => "<span class="elsevierStyleTextfn">Letter to the Editor</span>"
    "titulo" => "Evaluation of a Patient With Temporomandibular Joint Disorders in Paget&#39;s Disease of Bone"
    "tieneTextoCompleto" => true
    "saludo" => "Dear Editor&#44;"
    "paginas" => array:1 [
      0 => array:1 [
        "paginaInicial" => "e74"
      ]
    ]
    "autores" => array:1 [
      0 => array:4 [
        "autoresLista" => "Jos&#233; Dario S&#225;nchez L&#243;pez, Paolo Cariati, Miguel Angel P&#233;rez de Perceval Tara"
        "autores" => array:3 [
          0 => array:4 [
            "nombre" => "Jos&#233; Dario"
            "apellidos" => "S&#225;nchez L&#243;pez"
            "email" => array:1 [
              0 => "josed.sanchez.sspa@juntadeandalucia.es"
            ]
            "referencia" => array:1 [
              0 => array:2 [
                "etiqueta" => "&#42;"
                "identificador" => "cor0005"
              ]
            ]
          ]
          1 => array:2 [
            "nombre" => "Paolo"
            "apellidos" => "Cariati"
          ]
          2 => array:2 [
            "nombre" => "Miguel Angel"
            "apellidos" => "P&#233;rez de Perceval Tara"
          ]
        ]
        "afiliaciones" => array:1 [
          0 => array:2 [
            "entidad" => "Servicio de Cirug&#237;a Oral y Maxilofacial&#44; Hospital Universitario Virgen de las Nieves&#44; Granada&#44; Spain"
            "identificador" => "aff0005"
          ]
        ]
        "correspondencia" => array:1 [
          0 => array:3 [
            "identificador" => "cor0005"
            "etiqueta" => "&#8270;"
            "correspondencia" => "Corresponding author&#46;"
          ]
        ]
      ]
    ]
    "titulosAlternativos" => array:1 [
      "es" => array:1 [
        "titulo" => "Evaluaci&#243;n de un paciente con trastornos de la articulaci&#243;n temporomandibular en la enfermedad &#243;sea de Paget"
      ]
    ]
    "resumenGrafico" => array:2 [
      "original" => 0
      "multimedia" => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 625
            "Ancho" => 750
            "Tamanyo" => 30080
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">CT scan showing condylar deformity with osteosclerosis&#44; flattening and osteophytes&#46;</p>"
        ]
      ]
    ]
    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">Paget&#39;s disease of bone &#40;PDB&#41; is a chronic process characterised by an increase in bone remodelling&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">1</span></a> Its clinical presentation varies and may consist of asymptomatic cases detected by an increase in serum levels of alkaline phosphatase &#40;AP&#41; or coincidental radiological findings&#44; or even bone pain and bone deformity&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">2</span></a></p><p id="par0010" class="elsevierStylePara elsevierViewall">First line treatment is aimed at reducing pain &#40;NSAIDS&#44; paracetamol&#44; COX-2 inhibitors&#41; and later to reducing the speed of bone turnover &#40;calcitonin and bisphosphonates &#91;BP&#93;&#46;&#41;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">3</span></a></p><p id="par0015" class="elsevierStylePara elsevierViewall">The aim of this clinical case is to show an unusual presentation in TMJ within the context of a PDB&#44; and also to show what treatment may be followed&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">We present the case of a 72-year-old patient who was diagnosed with a monostotic variant of PDB &#40;affecting the ulna&#41; of 5-year duration&#44; which was initially treated with analgesics &#40;NSAIDS&#44; paracetamol&#44; COX-2 inhibitors&#41; and later with oral alendronate at a dose of 40<span class="elsevierStyleHsp" style=""></span>mg quarterly together with vitamin D &#40;400<span class="elsevierStyleHsp" style=""></span>U&#41; and Calcium &#40;1&#46;5<span class="elsevierStyleHsp" style=""></span>g&#41; supplements&#46; The patient was referred to our department suffering from pain &#40;VAS<span class="elsevierStyleHsp" style=""></span>&#61;<span class="elsevierStyleHsp" style=""></span>7&#47;10&#41; in the right temporomandibular Joint &#40;TMJ&#41; and a reduction of oral opening &#40;&#60;2&#46;5<span class="elsevierStyleHsp" style=""></span>cm&#41;&#46; The examination was completed with computerised axial tomography &#40;CAT&#41; which revealed condylar deformity with osteosclerosis and osteophytes &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>&#41;&#46; The diagnosis made was arthropathy of the TMJ and was initially treated with a jaw release splint&#44; rehabilitation exercises&#44; analgesic treatment and muscle relaxants&#46; Following periodic three-monthly check-ups after a year of treatment a reduction in pain was noted &#40;VAS&#58; 3&#47;10&#41; and an increase in joint function with oral opening above 3<span class="elsevierStyleHsp" style=""></span>cm&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0025" class="elsevierStylePara elsevierViewall">Involvement of the jawbones and specifically of the TMJ in PDB is a rare occurrence&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">4</span></a></p><p id="par0030" class="elsevierStylePara elsevierViewall">Despite not verifying jawbone involvement&#44; and without being able to rule out other causes &#40;osteoarthritis&#44; arthritis&#41;&#44; due to the absence of previous events&#44; this case was suggestive of an isolated involvement of the TMJ provoked by continuous stress to which the articular condyles are subjected as a consequence of mastication&#44; leading to degenerative phenomena with episodes of bone remodelling&#46; However&#44; confirmation of this hypothesis would require the undertaking of more specific tests &#40;bone scintigraphy&#41;&#46;</p><p id="par0035" class="elsevierStylePara elsevierViewall">Clinical signs of improvement globally appreciated corroborate the current trend<a class="elsevierStyleCrossRefs" href="#bib0055"><span class="elsevierStyleSup">5&#44;6</span></a> that treatment with second and third generation BPs &#40;pamidronate&#44; alendronate&#44; risedronate&#44; zoledronate&#41; are more effective than calcitonin and etidronate for serum and degenerative disease control&#46;</p></span>"
    "pdfFichero" => "main.pdf"
    "tienePdf" => true
    "NotaPie" => array:1 [
      0 => array:2 [
        "etiqueta" => "&#9734;"
        "nota" => "<p class="elsevierStyleNotepara" id="npar0005">Please cite this article as&#58; S&#225;nchez L&#243;pez JD&#44; Cariati P&#44; P&#233;rez de Perceval Tara MA&#46; Evaluaci&#243;n de un paciente con trastornos de la articulaci&#243;n temporomandibular en la enfermedad &#243;sea de Paget&#46; Reumatol Clin&#46; 2019&#59;15&#58;e74&#46;</p>"
      ]
    ]
    "multimedia" => array:1 [
      0 => array:7 [
        "identificador" => "fig0005"
        "etiqueta" => "Fig&#46; 1"
        "tipo" => "MULTIMEDIAFIGURA"
        "mostrarFloat" => true
        "mostrarDisplay" => false
        "figura" => array:1 [
          0 => array:4 [
            "imagen" => "gr1.jpeg"
            "Alto" => 625
            "Ancho" => 750
            "Tamanyo" => 30080
          ]
        ]
        "descripcion" => array:1 [
          "en" => "<p id="spar0005" class="elsevierStyleSimplePara elsevierViewall">CT scan showing condylar deformity with osteosclerosis&#44; flattening and osteophytes&#46;</p>"
        ]
      ]
    ]
    "bibliografia" => array:2 [
      "titulo" => "References"
      "seccion" => array:1 [
        0 => array:2 [
          "identificador" => "bibs0015"
          "bibliografiaReferencia" => array:6 [
            0 => array:3 [
              "identificador" => "bib0035"
              "etiqueta" => "1"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Pathogenesis and management of Paget&#39;s disease of bone"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "S&#46;H&#46; Ralston"
                            1 => "A&#46;L&#46; Langston"
                            2 => "I&#46;R&#46; Reid"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1016/S0140-6736(08)61035-1"
                      "Revista" => array:7 [
                        "tituloSerie" => "Lancet"
                        "fecha" => "2008"
                        "volumen" => "372"
                        "paginaInicial" => "155"
                        "paginaFinal" => "163"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/18620951"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0022202X15000512"
                          "estado" => "S300"
                          "issn" => "0022202X"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            1 => array:3 [
              "identificador" => "bib0040"
              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Paget&#39;s disease of bone"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:1 [
                            0 => "M&#46;P&#46; Whyte"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1056/NEJMcp060278"
                      "Revista" => array:7 [
                        "tituloSerie" => "N Engl J Med"
                        "fecha" => "2006"
                        "volumen" => "355"
                        "paginaInicial" => "593"
                        "paginaFinal" => "600"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/16899779"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0022202X17313076"
                          "estado" => "S300"
                          "issn" => "0022202X"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            2 => array:3 [
              "identificador" => "bib0045"
              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Clinical and genetic advances in Pagets disease of bone&#58; a review"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:3 [
                            0 => "N&#46; Alonso"
                            1 => "I&#46; Calero-Paniagua"
                            2 => "J&#46; del Pino-Montes"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1007/s12018-016-9226-0"
                      "Revista" => array:6 [
                        "tituloSerie" => "Clin Rev Bone Miner Metab"
                        "fecha" => "2017"
                        "volumen" => "15"
                        "paginaInicial" => "37"
                        "paginaFinal" => "48"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/28255281"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            3 => array:3 [
              "identificador" => "bib0050"
              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Discopathy and osteoarthritis of temporomandibular joint in a patient with Paget disease and osteoporosis&#46; A case report"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "T&#46; Badel"
                            1 => "D&#46; Podoreski"
                            2 => "S&#46; Kraljevic"
                            3 => "J&#46; Keros"
                            4 => "L&#46; Krapac"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Bone"
                        "fecha" => "2009"
                        "volumen" => "44"
                        "paginaInicial" => "339"
                        "paginaFinal" => "350"
                      ]
                    ]
                  ]
                ]
              ]
            ]
            4 => array:3 [
              "identificador" => "bib0055"
              "etiqueta" => "5"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Paget&#39;s disease of bone&#58; an endocrine society clinical practice guideline"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
                            0 => "F&#46;R&#46; Singer"
                            1 => "H&#46;G&#46; Bone 3rd"
                            2 => "D&#46;J&#46; Hosking"
                            3 => "K&#46;W&#46; Lyles"
                            4 => "M&#46;H&#46; Murad"
                            5 => "I&#46;R&#46; Reid"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1210/jc.2014-2910"
                      "Revista" => array:7 [
                        "tituloSerie" => "J Clin Endocrinol Metab"
                        "fecha" => "2014"
                        "volumen" => "99"
                        "paginaInicial" => "4408"
                        "paginaFinal" => "4422"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/25406796"
                            "web" => "Medline"
                          ]
                        ]
                        "itemHostRev" => array:3 [
                          "pii" => "S0022202X15000664"
                          "estado" => "S300"
                          "issn" => "0022202X"
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
            5 => array:3 [
              "identificador" => "bib0060"
              "etiqueta" => "6"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Comparison of different intravenous bisphosphonate regimens for Paget&#39;s disease of bone"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:5 [
                            0 => "D&#46;L&#46; Merlotti"
                            1 => "G&#46; Gennari"
                            2 => "F&#46; Martini"
                            3 => "V&#46; Valleggi"
                            4 => "A&#46; de Paola"
                          ]
                        ]
                      ]
                    ]
                  ]
                  "host" => array:1 [
                    0 => array:2 [
                      "doi" => "10.1359/jbmr.070704"
                      "Revista" => array:6 [
                        "tituloSerie" => "J Bone Miner Res"
                        "fecha" => "2007"
                        "volumen" => "22"
                        "paginaInicial" => "1510"
                        "paginaFinal" => "1517"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/17605632"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
    ]
  ]
  "idiomaDefecto" => "en"
  "url" => "/21735743/0000001500000005/v1_201910260908/S2173574318301709/v1_201910260908/en/main.assets"
  "Apartado" => array:4 [
    "identificador" => "8400"
    "tipo" => "SECCION"
    "en" => array:2 [
      "titulo" => "Letters to the Editor"
      "idiomaDefecto" => true
    ]
    "idiomaDefecto" => "en"
  ]
  "PDF" => "https://static.elsevier.es/multimedia/21735743/0000001500000005/v1_201910260908/S2173574318301709/v1_201910260908/en/main.pdf?idApp=UINPBA00004M&text.app=https://reumatologiaclinica.org/"
  "EPUB" => "https://multimedia.elsevier.es/PublicationsMultimediaV1/item/epub/S2173574318301709?idApp=UINPBA00004M"
]
Article information
ISSN: 21735743
Original language: English
The statistics are updated each day
Year/Month Html Pdf Total
2024 October 39 16 55
2024 September 45 30 75
2024 August 60 50 110
2024 July 57 32 89
2024 June 52 29 81
2024 May 35 22 57
2024 April 44 22 66
2024 March 39 26 65
2024 February 28 25 53
2024 January 44 18 62
2023 December 39 28 67
2023 November 53 34 87
2023 October 33 35 68
2023 September 64 38 102
2023 August 35 18 53
2023 July 43 20 63
2023 June 38 22 60
2023 May 41 21 62
2023 April 30 7 37
2023 March 56 25 81
2023 February 44 22 66
2023 January 44 10 54
2022 December 53 18 71
2022 November 40 21 61
2022 October 44 30 74
2022 September 42 30 72
2022 August 38 39 77
2022 July 35 29 64
2022 June 50 28 78
2022 May 38 42 80
2022 April 49 40 89
2022 March 46 43 89
2022 February 59 29 88
2022 January 46 37 83
2021 December 37 42 79
2021 November 41 38 79
2021 October 53 53 106
2021 September 35 34 69
2021 August 38 29 67
2021 July 28 24 52
2021 June 28 29 57
2021 May 48 35 83
2021 April 80 77 157
2021 March 46 38 84
2021 February 42 17 59
2021 January 40 23 63
2020 December 32 20 52
2020 November 85 13 98
2020 October 80 19 99
2020 September 32 26 58
2020 August 29 20 49
2020 July 26 13 39
2020 June 26 14 40
2020 May 28 13 41
2020 April 20 16 36
2020 March 3 1 4
2019 November 1 0 1
Show all

Follow this link to access the full text of the article

Idiomas
Reumatología Clínica (English Edition)
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?