Journal Information
Vol. 15. Issue 5.
Pages e74 (September - October 2019)
Vol. 15. Issue 5.
Pages e74 (September - October 2019)
Letter to the Editor
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Evaluation of a Patient With Temporomandibular Joint Disorders in Paget's Disease of Bone
Evaluación de un paciente con trastornos de la articulación temporomandibular en la enfermedad ósea de Paget
José Dario Sánchez López
Corresponding author
, Paolo Cariati, Miguel Angel Pérez de Perceval Tara
Servicio de Cirugía Oral y Maxilofacial, Hospital Universitario Virgen de las Nieves, Granada, Spain
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Dear Editor,

Paget's disease of bone (PDB) is a chronic process characterised by an increase in bone remodelling.1 Its clinical presentation varies and may consist of asymptomatic cases detected by an increase in serum levels of alkaline phosphatase (AP) or coincidental radiological findings, or even bone pain and bone deformity.2

First line treatment is aimed at reducing pain (NSAIDS, paracetamol, COX-2 inhibitors) and later to reducing the speed of bone turnover (calcitonin and bisphosphonates [BP].)3

The aim of this clinical case is to show an unusual presentation in TMJ within the context of a PDB, and also to show what treatment may be followed.

We present the case of a 72-year-old patient who was diagnosed with a monostotic variant of PDB (affecting the ulna) of 5-year duration, which was initially treated with analgesics (NSAIDS, paracetamol, COX-2 inhibitors) and later with oral alendronate at a dose of 40mg quarterly together with vitamin D (400U) and Calcium (1.5g) supplements. The patient was referred to our department suffering from pain (VAS=7/10) in the right temporomandibular Joint (TMJ) and a reduction of oral opening (<2.5cm). The examination was completed with computerised axial tomography (CAT) which revealed condylar deformity with osteosclerosis and osteophytes (Fig. 1). The diagnosis made was arthropathy of the TMJ and was initially treated with a jaw release splint, rehabilitation exercises, analgesic treatment and muscle relaxants. Following periodic three-monthly check-ups after a year of treatment a reduction in pain was noted (VAS: 3/10) and an increase in joint function with oral opening above 3cm.

Fig. 1.

CT scan showing condylar deformity with osteosclerosis, flattening and osteophytes.


Involvement of the jawbones and specifically of the TMJ in PDB is a rare occurrence.4

Despite not verifying jawbone involvement, and without being able to rule out other causes (osteoarthritis, arthritis), due to the absence of previous events, this case was suggestive of an isolated involvement of the TMJ provoked by continuous stress to which the articular condyles are subjected as a consequence of mastication, leading to degenerative phenomena with episodes of bone remodelling. However, confirmation of this hypothesis would require the undertaking of more specific tests (bone scintigraphy).

Clinical signs of improvement globally appreciated corroborate the current trend5,6 that treatment with second and third generation BPs (pamidronate, alendronate, risedronate, zoledronate) are more effective than calcitonin and etidronate for serum and degenerative disease control.

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Please cite this article as: Sánchez López JD, Cariati P, Pérez de Perceval Tara MA. Evaluación de un paciente con trastornos de la articulación temporomandibular en la enfermedad ósea de Paget. Reumatol Clin. 2019;15:e74.

Copyright © 2017. Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología
Reumatología Clínica (English Edition)
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