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Original Article
Effectiveness and safety of tocilizumab in monotherapy in biologic-naïve and non-naïve patients with rheumatoid arthritis in a real-world setting
Eficacia y seguridad de tocilizumab en monoterapia en pacientes con artritis reumatoide naive y no naive a biológicos en un entorno del mundo real
Sara Marsal Barrila, Mª Auxiliadora Martin-Martinezb,
Corresponding author
xily_mm@yahoo.com

Corresponding author.
, Francisco Javier Blanco-Garciac, Antonio Fernández-Nebrod, Rosario García de Vicuñae, Jesús Tornero-Molinaf,g, Fernando Sánchez-Alonsob, Marta Novella-Navarroh, Alejandro Escudero-Contrerasi, Juan José Alegre-Sanchoj, Ana Urruticoechea-Aranak, Maria Sagrario Bustabad-Reyesl, Pilar Trenor-Larrazm, Trinidad Pérez-Sandovaln, Maria Isabel Tevar-Sánchezo, Jesús T. Sánchez-Costab, Enrique Raya-Álvarezp
a Rheumatology Department, Hospital Universitario Vall d’Hebron, Passeig de la Vall d’Hebron, 119, 129, 08035 Barcelona, Spain
b Research Unit of Spanish Society of Rheumatology, Calle Marqués del Duero, 5 Primero A, 28001 Madrid, Spain
c Rheumatology Department, Complejo Hospitalario Universitario A Coruña, As Xubias, 84, 15006 A Coruña, Spain
d Rheumatology Department, Biomedical Research Institute of Málaga (IBIMA), Hospital Universitario Regional de Málaga, Av. de Carlos Haya, 84, 29010 Málaga, Spain
e Rheumatology Department, Hospital Universitario La Princesa, Calle de Diego de León, 62, 28006, Madrid, Spain
f Rheumatology Department, Hospital Universitario de Guadalajara, Calle Donante de Sangre, S/N, 19002 Guadalajara, Spain
g Medicine and Medical Specialties Departament, University of Alcalá, Campus Universitario - C/ 19, Av. de Madrid, Km 33,600, 28871 Alcalá de Henares, Madrid, Spain
h Rheumatology Department, Hospital Universitario de Torrejón, Calle Mateo Inurria, s/n, 28850 Torrejón de Ardoz, Madrid, Spain
i Rheumatology Department, Hospital Universitario Reina Sofia, Córdoba. Av. Menéndez Pidal, s/n, 14004, Córdoba, Spain
j Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Av. de Gaspar Aguilar, 90, 46017 Valencia, Spain
k Rheumatology Department, Hospital Can Misses, Carrer de Corona, s/n, 07800 Ibiza, Islas Baleares, Spain
l Rheumatology Department, Hospital Universitario de Canarias, Carretera Cuesta Taco, 0, 38320 Santa Cruz de Tenerife, Islas Canarias, Spain
m Rheumatology Department, Hospital Clínico Universitario de Valencia, Av. de Blasco Ibáñez, 17, 46010 Valencia, Spain
n Rheumatoloy Department, Complejo Asistencial Universitario de León, Calle Altos de nava, s/n, 24001 León, Spain
o Rheumatoloy Department, Hospital Vega Baja, Ctra. Orihuela – Almoradí S/N, 03314 San Bartolomé, Orihuela, Spain
p Rheumatoloy Department, Hospital Universitario San Cecilio, Av. de la Investigación, s/n, 18016 Granada, Spain
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