Article information
Abstract
A 31-year-old woman with a prior history of an overlap syndrome of systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) developed fever, pericarditis with pericardial effusion and a rapidly progressive fatal interstitial lung disease. Diagnostic test and procedures, differential diagnosis and therapeutic approach are discussed.
Keywords:
Interstitial lung disease
Pericarditis
Overlap syndrome
Resumen
Paciente de 31 años, con historia de síndrome de superposición de lupus eritematoso sistémico y esclerosis sistémica que desarrolla un cuadro caracterizado por fiebre, pericarditis con derrame pericárdico y enfermedad pulmonar rápidamente progresiva y fatal. Se discuten aspectos diagnósticos e indicaciones terapéuticas.
Palabras clave:
Enfermedad intersticial pulmonar
Pericarditis
Síndrome de superposición
Full text is only aviable in PDF
References
[1.]
P. Gourh, F.C. Arnett, F.K. Tan, S. Assassi, D. Divecha, G. Paz, et al.
Association of TNFSF4 (OX40L) polymorphisms with susceptibility to systemic sclerosis.
Ann Rheum Dis., 69 (2010), pp. 550-555
[2.]
Y. Allanore, P. Dieude, C. Boileau.
Genetic background of systemic sclerosis: autoimmune genes take centre stage.
Rheumatology (Oxford)., 49 (2010), pp. 203-210
[3.]
B. Rueda, M.V. Reddy, M.A. González-Gay, A. Balsa, D. Pascual-Salcedo, I.F. Petersson, et al.
Analysis of IRF5 gene functional polymorphisms in rheumatoid arthritis.
Arthritis Rheum., 54 (2006), pp. 3815-3819
[4.]
S.V. Kozyrev, A.K. Abelson, J. Wojcik, A. Zaghlool, M.V. Linga Reddy, E. Sánchez, et al.
Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus.
Nat Genet., 40 (2008), pp. 211-216
[5.]
M. Cutolo, C. Pizzorni, M.E. Secchi, A. Sulli.
Capillaroscopy.
Best Pract Res Clin Rheumatol, 22 (2008), pp. 1093-1108
[6.]
E. Rosato, F. Borghese, S. Pisarri, F. Salsano.
Laser Doppler perfusión imaging is useful in the study of Raynaud's phenomenon and improves the capillaroscopic diagnosis.
J Rheumatol., 36 (2009), pp. 2257-2263
[7.]
K.O. Leslie, S. Trahan, J. Gruden.
Pulmonary pathology of the rheumatic diseases.
Semin Respir Crit Care Med., 28 (2007), pp. 369-378
[8.]
M.E. Falagas, K.G. Manta, G.I. Betsi, G. Pappas.
Infection-related morbidity and mortality in patients with connective tissue diseases: a systematic review.
Clin Rheumatol., 26 (2007), pp. 663-670
[9.]
J.J. Swigris, A. Fischer, J. Gillis, J. Gilles, R.T. Meehan, K.K. Brown.
Pulmonary and thrombotic manifestations of systemic lupus erythematosus.
Chest., 133 (2008), pp. 271-280
[10.]
J.S. Román, F.J. Hernández, M.J. Palma, C.O. Medina.
Diagnosis and treatment of pulmonary hypertension.
Rev Clin Esp., 208 (2008), pp. 142-155
[11.]
J. Pope.
An update in pulmonary hypertension in systemic lupus erythematosus−do we need to know about it?.
Lupus., 17 (2008), pp. 274-277
[12.]
F. Capron.
New classification of interstitial lung disease.
Rev Pneumol Clin., 61 (2005), pp. 133-140
[13.]
S.V. Kocheril, B.E. Appleton, E.C. Somers, E.A. Kazerooni, K.R. Flaherty, F.J. Martínez, et al.
Comparison of disease progression and mortality of connective tissue diseaserelated interstitial lung disease and idiopathic interstitial pneumonia.
Arthritis Rheum., 53 (2005), pp. 549-557
[14.]
K.M. Antoniou, G. Margaritopoulos, F. Economidou, N.M. Siafakas.
Pivotal clinical dilemmas in collagen vascular diseases associated with interstitial lung involvement.
Eur Respir J., 33 (2009), pp. 882-896
[15.]
A. Fischer, J.J. Swigris, S.D. Groshong, C.D. Cool, H. Sahin, D.A. Lynch, et al.
Clinically significant interstitial lung disease in limited scleroderma: histopathology, clinical features, and survival.
Chest., 134 (2008), pp. 601-605
[16.]
D.A. Lynch, W.D. Travis, N.L. Müller, J.R. Galvin, D.M. Hansell, P.A. Grenier, et al.
Idiopathic interstitial pneumonias: CT features.
Radiology., 236 (2005), pp. 10-21
[17.]
W.T. Miller Jr., R.M. Shah.
Isolated diffuse ground-glass opacity in thoracic CT: causes and clinical presentations.
AJR Am J Roentgenol., 184 (2005), pp. 613-622
[18.]
S. Chandra, S.J. Shah, T. Thenappan, S.L. Archer, S. Rich, M. Gomberg-Maitland.
Carbon monoxide diffusing capacity and mortality in pulmonary arterial hypertension.
J Heart Lung Transplant., (2009),
[19.]
O.C. Meyer, N. Fertig, M. Lucas, N. Somogyi, T.A. Medsger Jr..
Disease subsets, antinuclear antibody profile, and clinical features in 127 French and 247 US adult patients with systemic sclerosis.
J Rheumatol., 34 (2007), pp. 104-109
[20.]
J.M. Pego-Reigosa, D.A. Medeiros, D.A. Isenberg.
Respiratory manifestations of systemic lupus erythematosus: old and new concepts.
Best Pract Res Clin Rheumatol., 23 (2009), pp. 469-480
[21.]
S.P. Toya, G.E. Tzelepis.
Association of the shrinking lung syndrome in systemic lupus erythematosus with pleurisy: a systematic review.
Semin Arthritis Rheum., 39 (2009), pp. 30-37
[22.]
R. Cervera, M.A. Khamashta, J. Font, G.D. Sebastiani, A. Gil, P. Lavilla, et al.
The European Working Party on Systemic Lupus Erythematosus: Systemic lupus erythematosus: clinical and immunologic patterns of disease expression in a cohort of 1,000 patients.
Medicine (Baltimore)., 72 (1993), pp. 113-124
[23.]
B.A. Pons-Estel, L.J. Catoggio, M.H. Cardiel, E.R. Soriano, S. Gentiletti, A.R. Villa, Grupo Latinoamericano de Estudio del Lupus, et al.
The GLADEL multinational Latin American prospective inception cohort of 1,214 patients with systemic lupus erythematosus: ethnic and disease heterogeneity among «Hispanics».
Medicine (Baltimore)., 83 (2004), pp. 1-17
[24.]
J. Rojas-Serrano, J. Pedroza, J. Regalado, J. Robledo, E. Reyes, J. Sifuentes-Osornio, et al.
High prevalence of infections in patients with systemic lupus erythematosus and pulmonary haemorrhage.
Lupus., 17 (2008), pp. 295-299
Copyright © 2011. Sociedad Española de Reumatología and Colegio Mexicano de Reumatología
