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Vol. 2. Núm. S3.
Esclerosis sistémica
Páginas S16-S19 (noviembre 2006)
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Vol. 2. Núm. S3.
Esclerosis sistémica
Páginas S16-S19 (noviembre 2006)
Esclerosis sistémica
Acceso a texto completo
Afección pulmonar en la esclerosis sistémica. Alveolitis, fibrosis e hipertensión arterial pulmonar
Pulmonary involvement in systemic sclerosis. Alveolitis, fibrosis and pulmonar arterial hypertension
Visitas
41482
Carmen Navarro
Autor para correspondencia
mcnavigo@yahoo.com

Correspondencia: Dra. C. Navarro. Instituto Nacional de Enfermedades Respiratorias. Calzada de Tlalpan 4502. Sección XVI. 14080 Tlalpan. México DF. México.
Subdirección de Investigación Clínica. Instituto Nacional de Enfermedades Respiratorias. Tlalpan. México DF. México
Este artículo ha recibido
Información del artículo
Resumen

La enfermedad pulmonar está presente en la mayoría de los pacientes con esclerodermia y actualmente es la principal causa de mortalidad. Dos tipos de daño predominan en estos pacientes: la enfermedad pulmonary intersticial y la hipertensión arterial pulmonar. Las dos son difíciles de diagnosticar en forma temprana; sin embargo, la búsqueda intencionada de alteraciones pulmonares mediante el uso de herramientas diagnósticas, como pruebas inmunológicas, pruebas de función respiratoria, tomografía de alta resolución, lavado bronquioloalveolar, ecocardiografía, cateterismo cardíaco o biopsia pulmonar, ayuda a detectar el grado de afección y permite instituir un tratamiento específico del órgano. Los avances en el uso de inmunomoduladores, vasodilatadores y otros fármacos emergentes ofrecen nuevas expectativas a los enfermos con esclerosis sistémica progesiva.

Palabras clave:
Enfermedad pulmonar intersticial
Hipertensión arterial pulmonar
Esclerosis sistémica progresiva

Pulmonary involvement in systemic sclerosis. Alveolitis, fibrosis and pulmonar arterial hypertension Lung disease is present in most of the patients with systemic sclerosis and is now the most important cause of mortality. Interstitial lung disease and pulmonary hypertension are, so far, the main disorders found and both are difficult to detect at the earliest stages. However, diagnostic tools such as immunological test, lung function test, high resolution CT, bronchoalveolar lavage, echocardiography, right-side cardiac catheterization, or lung biopsy are necessary to accurately evaluate the clinical status and allow to improve the management organ-specific ad hoc. Progress in immunological and vascular therapies as well as other emergence drugs offer new expectations to scleroderma patients.

Key words:
Interstitial lung disease
Pulmonary hypertension
Progressive systemic sclerosis
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Copyright © 2006. Elsevier España S.L. Barcelona
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