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noviembre - diciembre 2007 Síndrome nefrótico en esclerodermia
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Vol. 3. Núm. 6.
Páginas 270-272 (noviembre - diciembre 2007)
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Vol. 3. Núm. 6.
Páginas 270-272 (noviembre - diciembre 2007)
Casos clínicos
DOI: 10.1016/S1699-258X(07)73702-6
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Síndrome nefrótico en esclerodermia
Nephrotic Syndrome in Scleroderma
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María Luisa Velloso Feijoo
Autor para correspondencia
mlvelloso@gmail.com

Correspondencia: Dra. M.L. Velloso Feijoo. Avda. Ramón Carande, 7. Portal 4, 2.° A. 41013 Sevilla. España.
, Sergio Rodríguez Montero, Paz González Moreno, Lucía Mayordomo González, Eduardo Rejón Gieb, Jorge Fernández Alonso, José Luis Marenco de La Fuente
Sección de Reumatología. Hospital Universitario de Valme. Sevilla. España
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La afección renal es infrecuente en la esclerosis sistémica, a diferencia de otras colagenosis. La aparición de síndrome nefrótico se ha relacionado con el uso de fármacos, especialmente la D-penicilamina, o raramente como manifestación de amiloidosis secundaria, bastante infrecuente en la esclerosis sistémica. Presentamos un caso de síndrome nefrótico en una paciente con esclerosis sistémica, producido por una glomerulonefritis membranosa, descrito de forma excepcional en la literatura.

Palabras clave:
Esclerodermia difusa
Síndrome nefrótico
Glomerulonefritis membranosa

The renal affectation is infrequent in scleroderma, unlike other collagen diseases. The appearance of nephrotic syndrome has been related to the drug use, specially the D-penicilamine, or rarely as a manifestation of secondary amilodosis, quite infrequent in scleroderma. We report a case of nephrotic syndrome in a patient with systemic scleroderma, produced by a membranous glomerulonephritis, exceptionally described in literature.

Key words:
Difuse scleroderma
Nephrotic syndrome
Membranous glomerulonephritis
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Bibliografía
[1.]
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The relationship of hipertensión and renal failure in scleroderma (progresive systemic sclerosis) to structural and functional abnormalities of the renal cortical circulation.
Medicine, 53 (1974), pp. 1-46
Medline
[2.]
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Systemic sclerosis complicated with nephrotic síndrome: relevante with antiribosomal P antibody.
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S. Kondo, M. Tone, N. Teramoto, I. Katayama, H. Arai, K. Nishioka, et al.
Clinical studies of 15 cases of progressive systemic sclerosis associated with positive proteinuria and membranous glomerulonephritis.
Nippon Hifuka Gakkai Zasshi, 99 (1989), pp. 1105-1110
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A. Palma, A. Sanchez-Palencia, J.R. Armas, J.A. Milan, J. Fernandez-Sanz, F. Llach.
Progressive systemic scleroderma and nephrotic syndrome. An unusual association resulting in postpartum acute renal failure.
Arch Intern Med, 141 (1981), pp. 520-521
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Membranous nephritis in a patient with scleroderma: a case report.
Nephrol Dial Transplant, 11 (1996), pp. 363-364
Medline
Copyright © 2007. Elsevier España S.L Barcelona

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