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Case Report
Available online 25 December 2021
Crohn’s disease in a patient with systemic onset juvenile idiopathic arthritis. Association or associated side effect of treatment?
Enfermedad de Crohn en paciente con artritis idiopática juvenil de inicio sistémico: ¿asociación o complicación asociada al tratamiento?
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Laura Martín Pedraza,
Corresponding author
pedraz88@hotmail.com

Corresponding author.
, Rocío Galindo Zavalaa, Javier Blasco Alonsob, Víctor Manuel Navas Lópezb, Esmeralda Núñez Cuadrosa
a Sección de Reumatología Pediátrica, UGC Pediatría, Hospital Regional Universitario de Málaga, Málaga, Spain
b Sección de Gastroenterología y Nutrición Infantil, UGC Pediatría, Hospital Regional Universitario de Málaga, Málaga, Spain
Received 07 May 2021. Accepted 10 June 2021
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Table 1. Paediatric series of JIAs with subsequent development of IBD.
Abstract

The progression of systemic-onset juvenile idiopathic arthritis (JIAs) to the different forms of presentation of inflammatory bowel disease is extremely rare. We present the first report of a patient with SJIA that progressed to Crohn’s disease in which mutations have been detected in genes responsible for the adequate regulation of the innate immune system.

Keywords:
Crohn’s disease
Systemic-onset juvenile idiopathic arthritis
Paediatrics
Resumen

La evolución de la artritis idiopática juvenil de inicio sistémico (AIJs) hacia las diferentes formas de presentación de enfermedad inflamatoria intestinal es extremadamente infrecuente. Presentamos la que, hasta ahora, es la primera comunicación de un paciente con AIJs con evolución a enfermedad de Crohn en el que se han detectado mutaciones en genes responsables de la adecuada regulación del sistema inmune innato.

Palabras clave:
Enfermedad de Crohn
Artritis idiopática juvenil de inicio sistémico
Pediatría

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