Journal Information
Vol. 21. Issue 10.
(December 2025)
Share
Download PDF
More article options
Visits
3
Vol. 21. Issue 10.
(December 2025)
Original article
Diffuse idiopathic skeletal hyperostosis in patients with prediabetes
Hiperostosis esquelética idiopática difusa en pacientes con prediabetes
Visits
3
Ayfer Altıntasa, Emre Ali Acarb, Sadettin Uslub,
Corresponding author
sadouslu@gmail.com

Corresponding author.
, Ihsan Sebnem Orgücc, Zeliha Hekimsoyd, Timur Pirildarb
a Department of Internal Medicine, Celal Bayar University School of Medicine, Manisa, Turkey
b Department of Internal Medicine, Division of Rheumatology, Celal Bayar University School of Medicine, Manisa, Turkey
c Department of Radiology, Celal Bayar University School of Medicine, Manisa, Turkey
d Department of Internal Medicine, Division of Endocrinology and Metabolism, Celal Bayar University School of Medicine, Manisa, Turkey
This item has received
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Tables (2)
Table 1. Demographic and clinical characteristics of the study group.
Tables
Table 2. Demographic and clinical findings of patients with and without DISH.
Tables
Show moreShow less
Abstract
Objective

To investigate the frequency of diffuse idiopathic skeletal hyperostosis (DISH) in patients with prediabetes.

Material and methods

A total of 166 prediabetic patients were prospectively evaluated, of whom 67 with symptoms suggestive of DISH underwent thoracic and lumbar radiography. DISH was diagnosed according to Resnick and Niwayama criteria. Demographic, clinical and laboratory data were analyzed.

Results

DISH was diagnosed in 9 patients (13.4% of symptomatic; 5.4% overall). Patients with DISH were older and more frequently hypertensive compared to those without DISH (p=0.004 and p=0.047, respectively). Other parameters such as body mass index, fasting glucose, and smoking showed higher trends in the DISH group but did not reach statistical significance.

Conclusion

This is the first study to examine DISH in a prediabetic population. Our findings suggest a possible association between DISH and prediabetic status, although further studies are needed to confirm this relationship.

Keywords:
Diffuse idiopathic skeletal hyperostosis (DISH)
Prediabetes
Radiograph
Resumen
Objetivo

Investigar la frecuencia de la hiperostosis esquelética idiopática difusa (DISH, por sus siglas en inglés) en pacientes con prediabetes.

Material y métodos

Se evaluaron prospectivamente un total de 166 pacientes con prediabetes, de los cuales 67 con síntomas sugestivos de DISH fueron sometidos a radiografías torácicas y lumbares. El diagnóstico de DISH se estableció según los criterios de Resnick y Niwayama. Se analizaron los datos demográficos, clínicos y de laboratorio.

Resultados

Se diagnosticó DISH en 9 pacientes (13,4% de los sintomáticos; 5,4% del total). Los pacientes con DISH eran de mayor edad y presentaban con mayor frecuencia hipertensión en comparación con aquellos sin DISH (p=0,004 y p=0,047, respectivamente). Otros parámetros como el índice de masa corporal, la glucemia en ayunas y el tabaquismo mostraron una tendencia más elevada en el grupo con DISH, aunque sin alcanzar significación estadística.

Conclusión

Este es el primer estudio que examina la DISH en una población con prediabetes. Nuestros hallazgos sugieren una posible asociación entre la DISH y el estado prediabético, aunque se necesitan más estudios para confirmar esta relación.

Palabras clave:
Hiperostosis esquelética idiopática difusa (DISH)
Prediabetes
Radiografía

Article

These are the options to access the full texts of the publication Reumatología Clínica (English Edition)
Member
If you are member of Sociedad Española de Reumatología (SER) or the Colegio Mexicano de Reumatología (CMR):
Please go to the member area of SER or CMR and log in.
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

Reumatología Clínica (English Edition)

Purchase
Purchase article

Purchasing article the PDF version will be downloaded

Purchase now
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
Email
Idiomas
Reumatología Clínica (English Edition)
Article options
Tools