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Vol. 20. Issue 2.
Pages 104-107 (February 2024)
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Vol. 20. Issue 2.
Pages 104-107 (February 2024)
Case Report
Pleural tuberculosis and endocarditis as complications of multifactorial origin in granulomatosis with polyangiitis: Clinical case report
Tuberculosis pleural y endocarditis como complicaciones de origen multifactorial en granulomatosis con poliangítis. Reporte de caso clinico
Jesús Anguamea-Maldonado
Corresponding author

Corresponding author.
, Eduardo Sanchez-Zazueta, Rene Vidal-Morales
Instituto Mexicano del Seguro Social, Hospital General Regional No. 1 Ciudad Obregón, Sonora, Departamento de Medicina Interna, Sonora, Mexico
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Table 1. Diagnostic criteria for granulomatosis, accompanied by polyangiitis. American College of Rheumatology / European Alliance of Associations for Rheumatology 2022.

We present the case of a 36-year-old woman with a history of granulomatosis with polyangiitis; chronic kidney disease; systemic arterial hypertension. Debut with dyspnea, weakness, and hemoptysis, she was suspected in atypical pneumonia, discarded, persisting with tachypnea, tachycardia, chest pain. The protocol for pulmonary tuberculosis was started with negative sputum samples, positive blood culture for S. haemolyticus, chest tomography with left pneumothorax and ipsilateral pleural effusion, exudate-type pleural fluid was obtained, acid-fast staining, negative PCR for M. tuberculosis; A follow-up echocardiogram was performed due to a new murmur, reporting valvular vegetation, concluding a diagnosis of pleural tuberculosis and endocarditis as complications of multifactorial origin associated with immunosuppression in granulomatosis with polyangiitis.

Granulomatosis with polyangiitis
Pleural tuberculosis

Se presenta el caso de femenino de 36 años con antecedentes de granulomatosis con poliangitis; enfermedad renal crónica e hipertensión arterial sistémica. Debutó con disnea, debilidad y hemoptisis, se sospechó en neumonía atípica, descartándose, persistiendo con taquipnea, taquicardia, dolor torácico. Se inició protocolo para tuberculosis pulmonar con muestras de esputo negativas, hemocultivo positivo para S. haemolyticus, tomografía de tórax con neumotórax izquierdo y derrame pleural ipsilateral, se obtuvo liquido pleural tipo exudado, tinción alcohol ácido resistente y PCR para M. tuberculosis negativas; se realizó ecocardiograma de rastreo por soplo de nueva aparición, reportando vegetación valvular, concluyendo diagnóstico de tuberculosis pleural y endocarditis como complicaciones de origen multifactorial asociado a inmunosupresión en granulomatosis con poliangitis.

Palabras clave:
Granulomatosis con poliangitis
Tuberculosis pleural


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