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Available online 12 November 2024
Psychosis as a manifestation in systemic lupus erythematosus: treatment and long-term results. Number of cases
Psicosis como manifestación en el lupus eritematoso sistémico: tratamiento y resultados a largo plazo. Serie de casos
Maria Joselin Rodarte-Gallegos
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drajoss_reuma@outlook.com

Corresponding author.
, Ma. Azucena Ramos-Sánchez, Yadhira Mejia-Holguin, Ariana Maia Becerra-Márquez, Luciano Ortiz-Treviño
Unidad Médica de Alta Especialidad no. 25, Departamento de Reumatología, Instituto Mexicano del Seguro Social, Monterrey, Nuevo León, Mexico
Received 07 May 2024. Accepted 13 September 2024
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Table 1. Clinical and demographic characteristics of 5 women with psychiatric lupus.
Abstract

We present a case series of 5 patients with psychosis associated with SLE according to the ACR 1999 criteria. It presented as an initial clinical manifestation, clinically they had visual and auditory hallucinations, all the patients were women, average age 25 years, the accompanying manifestations were mostly mucocutaneous, articular and renal. Two patients presented antiphospholipid syndromes. The remission induction treatment was based on pulses of steroids and cyclophosphamide with a complete response in 4/5 patients, maintenance was left with mycophenolic acid and azathioprine.

Keywords:
Lupus
Neuropsychiatric lupus
Psychosis
Resumen

Presentamos una serie de casos de 5 pacientes con psicosis asociados a LES según los criterios ACR 1999. Se presentó como manifestación clínica inicial, clínicamente tenían alucinaciones visuales y auditivas, todas las pacientes fueron mujeres, edad promedio 25 años, las manifestaciones acompañantes fueron en su mayoría mucocutáneo, articular y renal. Dos pacientes presentaban síndromes antifosfolípidos. El tratamiento de inducción a la remisión se baso en pulsos de esteroides y ciclofosfamida con respuesta completa 4/5 pacientes, el mantenimiento se dejó con ácido micofenólico y azatioprina.

Palabras clave:
Lupus
Lupus neuropsiquiátrico
Psicosis

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