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Vol. 6. Issue 6.
Pages 303-305 (November - December 2010)
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Vol. 6. Issue 6.
Pages 303-305 (November - December 2010)
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Severe flare of Behcet's disease with intense mucucutaneous manifestations
Brote severo de la enfermedad de Behçet con manifestaciones mucocutáneas intensas
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José M. Martína,
Corresponding author
jmmart@eresmas.com

Corresponding author.
, Elisabeth Mateob, Carlos Monteagudoc, Esperanza Jordáa
a Servicios de Dermatología, Hospital Clínico Universitario, Valencia, Spain
b Medicina Interna, Hospital General Universitario, Valencia, Spain
c Anatomía Patológica, Hospital Clínico Universitario, Valencia, Spain
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Abstract

Behcet's disease is a multisystemic inflammatory disease with various manifestations at the skin level, especially in the form of acne-like lesions or erythema nodosum. Susceptibility to this disease is strongly linked to the presence of the HLA_B51 allele, although certain environmental factors such as infectious agents have also been implicated in its pathogenesis. We present the case of a patient with Behcet's disease who developed a severe flare characterized by lesions similar to those seen in Sweet's syndrome. Histologically we observed granulomatous vasculitis.

Keywords:
Cytomegalovirus
Behcet's disease
Resumen

La enfermedad de Behcet es un trastorno inflamatorio multisistemico que se manifiesta de forma muy variada a nivel cutaneo, especialmente en forma de lesiones acneiformes o de eritema nodoso. La susceptibilidad a padecer esta enfermedad se halla fuertemente ligada con la presencia del alelo HLA-B51, aunque determinados factores ambientales como agentes infecciosos tambien se han implicado en la patogenesis. Presentamos el caso de una paciente con una enfermedad de Behcet que desarrollo un brote severo con lesiones cutaneas analogas a las que se aprecian en el sindrome de Sweet. Histologicamente se apreciaron fenomenos de vasculitis granulomatosa.

Palabras clave:
Citomegalovirus
Enfermedad de Behçet
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