Publish in this journal
Journal Information
Vol. 8. Issue 4.
Pages 230 (July - August 2012)
Vol. 8. Issue 4.
Pages 230 (July - August 2012)
Letter to the Editor
DOI: 10.1016/j.reumae.2012.06.015
Full text access
Update of the Consensus on Osteoporosis of the Spanish Society of Rheumatology: A Lost Opportunity
Actualización del Consenso de Osteoporosis de la Sociedad Española de Reumatología: una oportunidad perdida
Visits
...
M. Pilar Aguado Acína,??
Corresponding author
paguado.hulp@salud.madrid.org

Corresponding author.
, Mónica Vázquez Díazb
a Servicio de Reumatología, Hospital Universitario La Paz, Madrid, Spain
b Servicio de Reumatología, Hospital Universitario Ramón y Cajal, Madrid, Spain
Article information
Full Text
Bibliography
Download PDF
Statistics
Full Text
To the Editor,

For some years we have experienced major conceptual changes in the field of osteoporosis. A better understanding of the epidemiology of fragility fractures, the identification of predictive risk factors and the safety of approved drugs, along with the marketing of new ones with more sophisticated mechanisms of action, have made a huge difference in addressing this disease in all countries. In this sense, the Spanish Society of Rheumatology has promoted the Osteoporosis Consensus update conducted in 2006 and published in the November issue of this journal1 as a reference to assist in treatment decisions. We are the country that consumes the greatest number of drugs for osteoporosis2 and incidence of hip fractures has not decreased in these years.3,4 Therefore, developing a consensus document from our partnership with “explicit” recommendations based on the best available and/or “implied” evidence, supported by common sense and experience of the experts is an a priori necessary initiative and a unique opportunity to gain leadership in the knowledge and management of this condition.

However, the consensus document does not meet the expectations offered in its introduction and objectives, which is advertised as a consensus but becomes “corporate thinking” and end up in the discussion as an “update”. But if we go on reading the text, apart from terminological considerations (not least because it involves different methodologies) the uncertainty increases and the key issues on which recommendations are made are treated as shallow and contradictory.

By way of example, in the section on risk assessment it talks about high and moderate risk factors (Table 1). High risk of fracture is considered when there are 2 high risk factors, but at what age? Then FRAX is postulated as the most recommended tool for calculating the risk of fracture, considering more than 15% specific for osteoporosis fracture risk (densitometric?). The authors then suggest a high fracture risk profile of greater than 20%. Calculated with the FRAX or if not, what? It concludes with the recommendation for the use of FRAX when performing densitometry, or when establishing a treatment. Is it not the other way around?

As for densitometry (DEXA), the indication is still considered as a separate recommendation, when it should already be integrated in the assessment of risk.5 Is the decrease in bone mineral density not a risk factor, with a known gradient of risk, covered in the FRAX?6

DEXA is recommended in early menopause as a first indication (considered by the panelists as a moderate risk factor), plus the presence of a major risk factor. Should we assume that smoking would also be another risk factor? The document does not explain why this and not another “moderate” or referenced in the bibliography risk factor is chosen specifically. Finally, the vagueness of consensus regarding the request by the patient enough for the indication of DEXA is also striking, if not disturbing.

With regard to treatment, it not only indicates is indicted in densitometric osteoporosis, but it is also advised for treatment of young women with “intense” osteopenia and major risk factors. What treatment is approved for the new term of “intense” osteopenia?

Recommendations are established for first and second line drugs, but no criteria are specified in cases where performance is the same (Effectiveness? Security? Cost?), as well as in the case of drugs for prevention and/or treatment. It states that “Calcitonin can be administered preemptively...”, while “Raloxifene is recommended as a second line treatment...”. In all age groups? Why when calcitonin has shown that it offers no proven prevention compared to raloxifene?

I could go on and on, because the “new” Osteoporosis Consensus of the SER reflects corporate influence, but does not collect, nor even attempt to address the uncertainties that we face as rheumatologists every day in our practice. Far from achieving uniformity in the management of our patients, it invites variability and an “anything goes” attitude, especially in a specialty, with rigorous concerns and with a disease so prevalent.

References
[1]
L. Pérez Edo, A. Alonso Ruiz, D. Roig Vilaseca, A. García Vadillo, N. Guañabens Gay, P. Peris, et al.
Actualización 2011 del consenso Sociedad Española de Reumatología de osteoporosis.
Reumatol Clin, 7 (2011), pp. 357-379
[2]
M. Richards.
Extent and causes of international variations in drug usage. A report for the Secretary of State for Health by Professor Sir Mike Richards CBE.
Central Office of Information, (2010),
[3]
M.M. Guerra, J.B. Rodriguez, E. Puga, M.A. Charle, C.S. Gómes, A. Preligueiro, et al.
Incidencia de la fractura de cadera osteoporótica en Galicia en relación con la dispensación de medicamentos con indicación en su prevención y tratamiento.
Aten Primaria, 43 (2011), pp. 82-88
[4]
I. Etxebarria, J. Mar, A. Arrospide, E. Esnal.
¿De verdad estamos reduciendo las fracturas de cadera? Análisis de la incidencia de fracturas de cadera en la Comunidad Autónoma Vasca.
SEIOMM, (2010),
[5]
J.A. Kanis, A. Oden, O. Johnell, H. Johansson, C. De Laet, J. Brown, et al.
The use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women.
Osteoporos Ont, 18 (2007), pp. 1033-1046
[6]
D.A. Marshall, O. Johnell, H. Wedel.
Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures.
BMJ, 18 (1986), pp. 1254-1259

Please cite this article as: Aguado Acín MP, Vázquez Díaz M. Actualización del Consenso de Osteoporosis de la Sociedad Española de Reumatología: una oportunidad perdida. Reumatol Clin. 2012;8:230.

Copyright © 2012. Elsevier España, S.L.. All rights reserved
Idiomas
Reumatología Clínica (English Edition)

Subscribe to our newsletter

Article options
Tools
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?

es en
Política de cookies Cookies policy
Utilizamos cookies propias y de terceros para mejorar nuestros servicios y mostrarle publicidad relacionada con sus preferencias mediante el análisis de sus hábitos de navegación. Si continua navegando, consideramos que acepta su uso. Puede cambiar la configuración u obtener más información aquí. To improve our services and products, we use "cookies" (own or third parties authorized) to show advertising related to client preferences through the analyses of navigation customer behavior. Continuing navigation will be considered as acceptance of this use. You can change the settings or obtain more information by clicking here.