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        "resumen" => "<p class="elsevierStyleSimplePara elsevierViewall">La crisis renal es una de las complicaciones m&#225;s graves de la esclerosis sist&#233;mica y se presenta en el 10&#37; de los pacientes&#46; Esta complicaci&#243;n se caracteriza por hipertensi&#243;n maligna&#44; hiperreninemia&#44; azoemia&#44; anemia hemol&#237;tica microangi&#243;tica e insuficiencia renal&#46; En la patogenia de la afecci&#243;n renal&#44; el principal mecanismo es el da&#241;o endotelial &#40;engrosamiento de los vasos arteriales&#41;&#44; hipoperfusi&#243;n renal que conduce a hiperplasia del aparato yuxtaglomerular y liberaci&#243;n de renina&#46; Las alteraciones histopatol&#243;gicas en el ri&#241;&#243;n son similares a las observadas en otras formas de hipertensi&#243;n maligna&#46; La crisis renal&#44; complicaci&#243;n anteriormente fatal&#44; actualmente se trata con &#233;xito mediante los inhibidores de la enzima de conversi&#243;n de la angiotensina&#46;</p>"
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