Estadísticas

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    "titulo" => "Neurobehcet&#39;s&#46; Comment&#58; &#8220;Neuro-Beh&#231;et Disease in the Central University Hospital of Asturias&#8221;"
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        "titulo" => "Neurobehcet&#39;s&#46; Comentario&#58; &#8220;La enfermedad de Neuro-Beh&#231;et en el Hospital Universitario Central de Asturias&#8221;"
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">We read with great interest the manuscript by Charca-Benavente et al&#46;&#44; about a frequency and profile of patients with neuro-Beh&#231;et&#39;s disease at the Central University Hospital of Asturias over a period of 37 years&#46;<a class="elsevierStyleCrossRef" href="#bib0020"><span class="elsevierStyleSup">1</span></a> We have the following comments&#46;</p><p id="par0010" class="elsevierStylePara elsevierViewall">Neurological manifestations&#44; found in 10&#8211;30&#37; of the patients with Behcet disease&#44; are recognized in the medical literature as Neurobeh&#231;et &#40;NB&#41;&#44; were described for the first time in 1941 by Knapp&#44; and in 1954 Cavara &#38; D&#769;Ermo coined the term NB&#44; and include migraine-like headache&#44; aseptic meningoencephalitis&#44; encephalopathy&#44; dementia&#44; seizures&#44; cranial nerve and bulbar palsy&#44; movement disorders&#44; cerebellar ataxia&#44; myelopathy&#44; neurosensorial hearing loss&#44; stroke&#44; psychiatric disturbances&#44; and a multiple sclerosis-like picture&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">2</span></a> They usually manifest within 5 years of onset&#46; Neurological complications progress to severe disability&#44; with a high mortality rate&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">3</span></a> Although this broad spectrum of manifestations is widely recognized&#44; myositis is rare&#46;</p><p id="par0015" class="elsevierStylePara elsevierViewall">However&#44; in the study by Charca-Benavente et al&#46;&#44; despite a considerable period of analysis&#44; it strikes us that there were no cases of muscle involvement&#44; so we would like to know to what the authors attribute this data&#46;</p><p id="par0020" class="elsevierStylePara elsevierViewall">The authors should have addressed the neuromuscular manifestations of NB&#46;BD must be considered as a differential diagnosis of localized or generalized inflammatory muscle disorders especially when findings of multiple tissue and organ lesions or any symptom of the characteristic triad are present&#46; Given the multisystemic nature of the syndrome&#44; it&#39;s not surprising the report of &#8220;unusual&#8221; manifestations that will further expand the wide spectrum of NB&#46;<a class="elsevierStyleCrossRef" href="#bib0025"><span class="elsevierStyleSup">2</span></a></p><p id="par0025" class="elsevierStylePara elsevierViewall">We are grateful to the authors for the excellent article addressing a relevant topic within BD&#44; allowing discussion to contribute with knowledge&#46;</p></span>"
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