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eosinophilic granulomatosis with polyangiitis&#44; giant cell arteritis&#44; Behcet&#39;s disease&#44; polyarteritis nodosa&#41;&#44; granulomatous diseases &#40;sarcoidosis&#44; Crohn&#39;s disease&#41;&#44; IgG4 related disease and Sjogren&#39;s syndrome&#46; These can be differentiated by serology and biopsy&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a> LM responds well to hydroxychloroquine with or without steroids&#46; Surgery may worsen it&#44; hence an accurate diagnosis is essential&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Contributor information</span><p id="par0015" class="elsevierStylePara elsevierViewall">RR &#38; SJ&#58; Identified and managed the case&#44; write the manuscript&#46; AC&#58; Identified and managed the case and reviewed the manuscript&#46; 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                            4 => "J&#46; David"
                            5 => "M&#46; Labelle"
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                      "Revista" => array:5 [
                        "tituloSerie" => "Eur J Radiol"
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                        "paginaFinal" => "131"
                      ]
                    ]
                  ]
                ]
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                      "titulo" => "Idiopathic granulomatous mastitis&#58; etiology&#44; clinical manifestation diagnosis and treatment"
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                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/35437114"
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              "referencia" => array:1 [
                0 => array:2 [
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                      "titulo" => "Mastitis in autoimmune diseases&#58; review of the literature diagnostic pathway&#44; and pathophysiological key players"
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                        "paginaInicial" => "958"
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                    ]
                  ]
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              ]
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Images in Clinical Rheumatology
Lupus Mastitis
Mastitis lúpica
Rashmi Roongta, Samir Joshi, Arghya Chattopadhyay
Autor para correspondencia
dr.a.chattopadhyay@gmail.com

Corresponding author.
, Alakendu Ghosh
Department of Clinical Immunology and Rheumatology, Institute of Postgraduate Medical Education and Research, Kolkata, West Bengal, India
Leído
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    "textoCompleto" => "<span class="elsevierStyleSections"><p id="par0005" class="elsevierStylePara elsevierViewall">A 45-year-old-woman presented with a non-pruritic&#44; maculopapular rash over her face&#44; chest&#44; and back for four months and a gradually progressive&#44; painful swelling of the right breast and right upper limb for the last two months&#46; There was no fever&#44; loss of weight or appetite&#44; or B-symptoms&#46; On examination&#44; an extensive rash was present on the face&#44; chest&#44; and back with discoid lesions over the ears&#46; The right breast and upper limb were erythematous&#44; swollen&#44; indurated&#44; and tender with peau d&#8217;orange changes &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>A&#41;&#46; There was no axillary or cervical lymphadenopathy&#46; Her hemogram was unremarkable and other investigations revealed positive anti-nuclear antibody &#40;ANA&#41;&#44; low complements&#44; and SS-A&#44; Ro-52&#44; and Ribosomal P positivity on ANA blot&#46; Ultrasound revealed diffuse dermal edema&#44; patent axillary and subclavian veins and no masses&#46; Skin biopsy from the rash showed interface dermatitis&#46; Because of a typical rash&#44; positive ANA&#44; and interface dermatitis on biopsy&#44; oral prednisolone&#44; and hydroxychloroquine was started for lupus-related mastitis and acute cutaneous lupus erythematosus rash&#46; There was rapid improvement in the breast and arm swelling over four weeks &#40;<a class="elsevierStyleCrossRef" href="#fig0005">Fig&#46; 1</a>B&#41;&#46;</p><elsevierMultimedia ident="fig0005"></elsevierMultimedia><p id="par0010" class="elsevierStylePara elsevierViewall">Lupus Mastitis &#40;LM&#41; is lupus panniculitis involving the mammary gland&#46; It is seen at a mean age of 40 years in patients with pre-established lupus and is associated with discoid lupus erythematosus&#46; It is rare with less than 50 documented cases&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> It presents as subcutaneous mass &#40;clinically and radiographically&#41; with skin changes and should be differentiated from infection and malignancy&#44; especially inflammatory breast carcinoma&#46; Irregular&#44; asymmetric masses&#44; coarse calcifications &#40;suggesting fat necrosis&#41;&#44; and fibrosis are seen on imaging&#46; Hyaline fat necrosis is the typical histological hallmark of LM&#46; Periseptal&#47;lobular panniculitis&#44; lobular lymphocytic infiltrates and microcalcifications are also seen&#46;<a class="elsevierStyleCrossRef" href="#bib0030"><span class="elsevierStyleSup">1</span></a> Bilateral lesions should prompt a workup for non-Hodgkin&#39;s lymphoma&#46;<a class="elsevierStyleCrossRef" href="#bib0035"><span class="elsevierStyleSup">2</span></a> Breast abscess and diabetic mastopathy should be considered in appropriate clinical situations&#46; Idiopathic Granulomatous Mastitis &#40;IGM&#41; is a close differential diagnosis with a possible autoimmune etiology but it rarely has calcifications on imaging and biopsy reveals non-caseating granulomas&#46;<a class="elsevierStyleCrossRef" href="#bib0040"><span class="elsevierStyleSup">3</span></a> Other connective tissue diseases causing mastitis are vasculitides &#40;granulomatosis with polyangiitis&#44; eosinophilic granulomatosis with polyangiitis&#44; giant cell arteritis&#44; Behcet&#39;s disease&#44; polyarteritis nodosa&#41;&#44; granulomatous diseases &#40;sarcoidosis&#44; Crohn&#39;s disease&#41;&#44; IgG4 related disease and Sjogren&#39;s syndrome&#46; These can be differentiated by serology and biopsy&#46;<a class="elsevierStyleCrossRef" href="#bib0045"><span class="elsevierStyleSup">4</span></a> LM responds well to hydroxychloroquine with or without steroids&#46; Surgery may worsen it&#44; hence an accurate diagnosis is essential&#46;<a class="elsevierStyleCrossRef" href="#bib0050"><span class="elsevierStyleSup">5</span></a></p><span id="sec0005" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0005">Contributor information</span><p id="par0015" class="elsevierStylePara elsevierViewall">RR &#38; SJ&#58; Identified and managed the case&#44; write the manuscript&#46; AC&#58; Identified and managed the case and reviewed the manuscript&#46; AG&#58; Identified the case and reviewed the manuscript&#46;</p></span><span id="sec0010" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0010">Patient consent</span><p id="par0020" class="elsevierStylePara elsevierViewall">Written consent has been obtained from the patient for this publication&#46;</p></span><span id="sec0015" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0015">Financial disclosures&#47;funding sources</span><p id="par0025" class="elsevierStylePara elsevierViewall">None of the authors have any financial disclosure or funding sources&#46;</p></span><span id="sec0020" class="elsevierStyleSection elsevierViewall"><span class="elsevierStyleSectionTitle" id="sect0020">Conflicts of interest</span><p id="par0030" class="elsevierStylePara elsevierViewall">None of the authors have any conflicts of interest to disclose&#46;</p></span></span>"
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                          "autores" => array:3 [
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                        "paginaInicial" => "901"
                        "paginaFinal" => "906"
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              "etiqueta" => "2"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
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                      "titulo" => "Lupus mastitis as a first manifestation of systemic disease&#58; about two cases with a review of the literature"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
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                            1 => "L&#46; Lalonde"
                            2 => "L&#46;M&#46; Sanchez"
                            3 => "J&#46; Richard-Chesnay"
                            4 => "J&#46; David"
                            5 => "M&#46; Labelle"
                          ]
                        ]
                      ]
                    ]
                  ]
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                    0 => array:1 [
                      "Revista" => array:5 [
                        "tituloSerie" => "Eur J Radiol"
                        "fecha" => "2017"
                        "volumen" => "92"
                        "paginaInicial" => "124"
                        "paginaFinal" => "131"
                      ]
                    ]
                  ]
                ]
              ]
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              "etiqueta" => "3"
              "referencia" => array:1 [
                0 => array:2 [
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                    0 => array:2 [
                      "titulo" => "Idiopathic granulomatous mastitis&#58; etiology&#44; clinical manifestation diagnosis and treatment"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => false
                          "autores" => array:6 [
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                            1 => "X&#46; Liu"
                            2 => "Q&#46; Meng"
                            3 => "X&#46; Han"
                            4 => "H&#46; Zhang"
                            5 => "Y&#46; Lv"
                          ]
                        ]
                      ]
                    ]
                  ]
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                        "fecha" => "2021"
                        "paginaInicial" => "1"
                        "paginaFinal" => "12"
                        "link" => array:1 [
                          0 => array:2 [
                            "url" => "https://www.ncbi.nlm.nih.gov/pubmed/35437114"
                            "web" => "Medline"
                          ]
                        ]
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "etiqueta" => "4"
              "referencia" => array:1 [
                0 => array:2 [
                  "contribucion" => array:1 [
                    0 => array:2 [
                      "titulo" => "Mastitis in autoimmune diseases&#58; review of the literature diagnostic pathway&#44; and pathophysiological key players"
                      "autores" => array:1 [
                        0 => array:2 [
                          "etal" => true
                          "autores" => array:6 [
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                            2 => "P&#46; Van de Perre"
                            3 => "I&#46; Millet"
                            4 => "A&#46;T&#46;J&#46; Maria"
                            5 => "J&#46; Morel"
                          ]
                        ]
                      ]
                    ]
                  ]
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                        "tituloSerie" => "J Clin Med"
                        "fecha" => "2020"
                        "volumen" => "9"
                        "paginaInicial" => "958"
                      ]
                    ]
                  ]
                ]
              ]
            ]
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              "etiqueta" => "5"
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                          "autores" => array:4 [
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                            3 => "A&#46; Irish"
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                  ]
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                      "Revista" => array:3 [
                        "tituloSerie" => "BMJ Case Rep"
                        "fecha" => "2011"
                        "paginaInicial" => "2011"
                      ]
                    ]
                  ]
                ]
              ]
            ]
          ]
        ]
      ]
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Información del artículo
ISSN: 1699258X
Idioma original: Inglés
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2024 Octubre 63 50 113
2024 Septiembre 67 34 101
2024 Agosto 88 55 143
2024 Julio 50 37 87
2024 Junio 61 36 97
2024 Mayo 68 45 113
2024 Abril 52 37 89
2024 Marzo 37 41 78
2024 Febrero 33 35 68
2024 Enero 37 28 65
2023 Diciembre 30 34 64
2023 Noviembre 56 47 103
2023 Octubre 41 34 75
2023 Septiembre 49 47 96
2023 Agosto 85 19 104
2023 Julio 51 32 83
2023 Junio 54 36 90
2023 Mayo 50 31 81
2023 Abril 37 28 65
2023 Marzo 43 51 94
2023 Febrero 37 34 71
2023 Enero 23 31 54
2022 Diciembre 69 44 113
2022 Noviembre 49 47 96
2022 Octubre 6 10 16
2022 Septiembre 1 0 1
2022 Julio 4 4 8
2022 Junio 11 0 11
2022 Mayo 2 2 4
2021 Octubre 1 0 1
2021 Septiembre 2 0 2
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Reumatología Clínica
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